A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

Perspectivas de la intensificación de procesos de adsorción empleando carbón activado para la remoción de contaminantes prioritarios del agua

This paper describes relevant topics involved in the intensification of adsorption processes for water treatment and purification using activated carbons. We have analyzed some key issues and challenges related to this research area giving emphasis to improve adsorption processes in multicomponent systems, which are relevant for water treatment under real-life conditions.En este trabajo se describen brevemente tópicos relevantes para la intensificación de procesos de adsorción para el tratamiento y purificación de agua empleando carbones activados. Se analizan las posibles implicaciones y retos que existen en esta área dando énfasis a mejoras para procesos de adsorción en sistemas multicomponentes, los cuales son relevantes para sistemas de tratamiento en condiciones reales de operación

A new synthesis route for bone chars using CO2 atmosphere and their application as fluoride adsorbents

This study describes a new synthesis route for bone chars using a CO2 atmosphere and their behavior as adsorbent for fluoride removal from water. Specifically, we have performed a detailed analysis of the adsorption properties of bone char samples obtained at different carbonization conditions and a comparative study with samples of bone char obtained via pyrolysis under nitrogen. Experimental results show that the nature of the gas atmosphere (CO2 versus N2) and the carbonization temperature play a major role to achieve an effective bone char for water defluoridation. In particular, the best adsorption properties of bone char for fluoride removal are obtained with those samples synthesized at 700 °C. Carbonization temperatures above 700 °C under CO2 atmosphere cause the dehydroxylation of the hydroxyapatite in the bone char, thus reducing its fluoride adsorption capacity. The maximum fluoride adsorption capacity for the bone char obtained in this study under CO2 atmosphere (i.e., 5.92 mg/g) is higher than those reported for commercial bone chars.Authors acknowledge the financial support provided by CONACYT, DGEST, Instituto Tecnológico de Aguascalientes and Universidad de Alicante

Physico-chemical characterization of metal-doped bone chars and their adsorption behavior for water defluoridation

New bone chars for fluoride adsorption from drinking water have been synthetized via metallic doping using aluminum and iron salts. A detailed statistical analysis of the metal doping process using the signal-to-noise ratios from Taguchi's experimental designs and its impact on the fluoride adsorption properties of modified bone chars have been performed. The best conditions, including the proper metallic salt, for metal doping were identified to improve the fluoride uptakes of modified bone chars. Results showed that the fluoride adsorption properties of bone chars can be enhanced up to 600% using aluminum sulfate for the surface modification. This aluminum-based adsorbent showed an adsorption capacity of 31 mg/g, which outperformed the fluoride uptakes reported for several adsorbents. Surface interactions involved in the defluoridation process were established using FTIR, DRX and XPS analysis. Defluoridation using the metal-doped bone chars occurred via an ion exchange process between fluoride ions and the hydroxyl groups on the adsorbent surface, whereas the Al(OH)xFy, FexFy, and CaF2 interactions could play also an important role in the removal process. These metal-doped adsorbents anticipate a promising behavior in water treatment, especially in developing countries where the efficiency – cost tradeoff is crucial for implementing new defluoridation technologies.Authors acknowledge the financial support provided by CONA-CYT, DGEST, Instituto Tecnológico de Aguascalientes (Mexico), Universidad de Alicante (Spain) and MINECO (Projects PCIN-2013-057 and MAT2013- 45008-P)

Müllerian anomalies prevalence diagnosed by hysteroscopy and laparoscopy in mexican infertile women: Results from a cohort study

Background: To evaluate the prevalence of Müllerian anomalies (MAs) in a cohort of infertile Mexican women candidates for infertility treatments (intrauterine insemination or IVF (In vitro fertilization) cycles). Methods: We performed a retrospective observational study on a cohort of consecutive women, who underwent hysteroscopy and laparoscopy as part of the basic infertility workup from 2002 to 2014, at our center. Our aim was to calculate the prevalence of MAs and each subtype. Results: A total of 4005 women were included in the study. The MA prevalence was 4.4% (95% CI; 3.8-5.1; n = 177). Among women with MAs, the prevalence of different MA types was: Septate uterus 54.2% (n = 96), arcuate uterus 15.8% (n = 28), bicornuate uterus 10.7% (n = 19), unicornuate uterus 8.5% (n = 15), didelphys uterus 6.2% (n = 11) and hypoplasia/agenesis 3.4% (n = 6), unclassifiable 1.1% (n = 2). Women with MAs who achieved pregnancy were: 33.3% (n = 59). The MA associated with the highest pregnancy rate was septate uterus after hysteroscopic correction, at 38.5% (37/96). Conclusions: The prevalence of MAs among infertile Mexican women can be considered as low, but not negligible. The septate uterus is the most common MA in women with infertility

A Phase III, Randomized, Clinical Trial of a 0.5% Timolol + 0.2% Brimonidine + 2.0% Dorzolamide Fixed Combination, Preservative-Free Ophthalmic Solution vs 0.5% Timolol + 0.2% Brimonidine + 2.0% Dorzolamide Fixed Combination in Patients with Controlled Primary Open-Angle Glaucoma

<p><b>Article full text</b></p> <p><br></p> <p>The full text of this article can be found here<b>. </b><a href="https://link.springer.com/article/10.1007/s40123-018-0128-8">https://link.springer.com/article/10.1007/s40123-018-0128-8</a></p><p></p> <p><br></p> <p><b>Provide enhanced content for this article</b></p> <p><br></p> <p>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <a href="http://www.medengine.com/Redeem/”mailto:[email protected]”"><b>[email protected]</b></a>.</p> <p><br></p> <p>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.</p> <p><br></p> <p>Other enhanced features include, but are not limited to:</p> <p><br></p> <p>• Slide decks</p> <p>• Videos and animations</p> <p>• Audio abstracts</p> <p>• Audio slides</p

<em>VNN1</em> Gene Expression Levels and the G-137T Polymorphism Are Associated with HDL-C Levels in Mexican Prepubertal Children

<div><h3>Background</h3><p><em>VNN1</em> gene expression levels and the G-137T polymorphism have been associated with high density lipoprotein cholesterol (HDL-C) levels in Mexican American adults. We aim to evaluate the contribution of <em>VNN1</em> gene expression and the G-137T variant to HDL-C levels and other metabolic traits in Mexican prepubertal children.</p> <h3>Methodology/Principal Findings</h3><p><em>VNN1</em> mRNA expression levels were quantified in peripheral blood leukocytes from 224 unrelated Mexican-Mestizo children aged 6–8 years (107 boys and 117 girls) and were genotyped for the G-137T variant (rs4897612). To account for population stratification, a panel of 10 ancestry informative markers was analyzed. After adjustment for admixture, the TT genotype was significantly associated with lower <em>VNN1</em> mRNA expression levels (<em>P</em> = 2.9 × 10⁻⁵), decreased HDL-C levels (β = −6.19, <em>P</em> = 0.028) and with higher body mass index (BMI) z-score (β = 0.48, <em>P</em> = 0.024) in the total sample. In addition, <em>VNN1</em> expression showed a positive correlation with HDL-C levels (r = 0.220; <em>P</em> = 0.017) and a negative correlation with BMI z-score (r = −0.225; <em>P</em> = 0.015) only in girls.</p> <h3>Conclusion/Significance</h3><p>Our data suggest that <em>VNN1</em> gene expression and the G-137T variant are associated with HDL-C levels in Mexican children, particularly in prepubertal girls.</p> </div