3,965 research outputs found
Assessing the Effects of Myxobolus cerebralis and Other Environmental Factors on the Dynamics, Abundance, and Distribution of Trout Populations in the Logan River, Utah
The presence of nonnative trout and the recent introduction of Myxobolus cerebralis in the Logan River drainage pose a threat to the native Bonneville cutthroat trout population (Oncorhynchus clarki Utah). The variability in the response of susceptible trout populations to M. cerebralis, causing agent of whirling disease, suggests that environmental factors may influence the effects of the parasite in infected environments. I investigated the relationship between temperature, discharge, substrate size, nutrient concentration (nitrogen and phosphorus), periphyton (chlorophyll a), and the relative abundance of Tubifex tubifex to the distribution, and prevalence of M. cerebralis in wild salmonid populations and sentinel fish in the mainstem of the Logan River and two of its tributaries. In addition, I investigated the potential influence of biotic (e.g., food availability, M. cerebralis prevalence) and abiotic factors (e.g., temperature) on the distribution abundance, and condition of salmonid fishes.
Differences in mean temperature and discharge across sites explained most (\u3e70%) of the variability in prevalence of M. cerebralis observed along the Logan River. However, the prevalence of the parasite was not related to other factors that can influence its life cycle, such as productivity and substrate composition. The results also indicate that the fish fauna presents a longitudinal change reflected in a zonation pattern. Cutthroat trout dominates the headwaters and high-elevation reaches, while reaches at lower elevations of the mainstem and tributaries were dominated by brown trout. The transition between these species was consistent with changes in environmental characteristics. Cutthroat trout dominates the fish community in mainstream reaches with the lowest average minimum temperature and highest diel temperatures, and where small boulders and small cobbles are the predominant substrate.
This study provides insights of the abiotic and biotic factors that affect the distribution, abundance, and condition of salmonid populations along the Logan River. Identifying these factors is crucial to effectively manage this and other trout streams, where ensuring the conservation of native cutthroat trout populations is a priority. Further, I present baseline information of the potential linkages between environmental factors and M. cerebralis distribution and prevelance, which could be used to develop plans to minimize the potential negative effects of this parasite on wild salmonid populations
A theoretical study of the mechanism of rearrangement of dihydropyrimidines into pyrroles
Pyrimidines, pyrroles, cycloreversion,CO extrusion, Two possible mechanisms for the transformation of a 1,4-dihydropyrrolo[3,2-b]pyrrole derivative into a tetrasubstituted pyrrole have been studied theoretically and one of them has been found in reasonable accord with the experimental data. This mechanismis part of the very rare example of rearrangement of dihydropyrimidines into pyrroles
Correction: Understanding MAOS through computational chemistry
Correction for 'Understanding MAOS through computational chemistry' by P. Prieto et al., Chem. Soc. Rev., 2017, 46, 431–451
Unpolarized states and hidden polarization
We capitalize on a multipolar expansion of the polarisation density matrix,
in which multipoles appear as successive moments of the Stokes variables. When
all the multipoles up to a given order vanish, we can properly say that the
state is th-order unpolarized, as it lacks of polarization information to
that order. First-order unpolarized states coincide with the corresponding
classical ones, whereas unpolarized to any order tally with the quantum notion
of fully invariant states. In between these two extreme cases, there is a rich
variety of situations that are explored here. The existence of \textit{hidden}
polarisation emerges in a natural way in this context.Comment: 7 pages, 3 eps-color figures. Submitted to PRA. Comments welcome
Material properties from air puff corneal deformation by numerical simulations on model corneas
19 págs.; 11 figs.; 2 tabs.Objective To validate a new method for reconstructing corneal biomechanical properties from air puff corneal deformation images using hydrogel polymer model corneas and porcine corneas. Methods Air puff deformation imaging was performed on model eyes with artificial corneas made out of three different hydrogel materials with three different thicknesses and on porcine eyes, at constant intraocular pressure of 15 mmHg. The cornea air puff deformation was modeled using finite elements, and hyperelastic material parameters were determined through inverse modeling, minimizing the difference between the simulated and the measured central deformation amplitude and central-peripheral deformation ratio parameters. Uniaxial tensile tests were performed on the model cornea materials as well as on corneal strips, and the results were compared to stress-strain simulations assuming the reconstructed material parameters. Results The measured and simulated spatial and temporal profiles of the air puff deformation tests were in good agreement (< 7% average discrepancy). The simulated stress-strain curves of the studied hydrogel corneal materials fitted well the experimental stress-strain curves from uniaxial extensiometry, particularly in the 0-0.4 range. Equivalent Young?s moduli of the reconstructed material properties from air-puff were 0.31, 0.58 and 0.48 MPa for the three polymer materials respectively which differed < 1% from those obtained from extensiometry. The simulations of the same material but different thickness resulted in similar reconstructed material properties. The air-puff reconstructed average equivalent Young?s modulus of the porcine corneas was 1.3 MPa, within 18% of that obtained from extensiometry. Conclusions Air puff corneal deformation imaging with inverse finite element modeling can retrieve material properties of model hydrogel polymer corneas and real corneas, which are in good correspondence with those obtained from uniaxial extensiometry, suggesting that this is a promising technique to retrieve quantitative corneal biomechanical properties.This work was supported by the European Research Council under the European Union’s Seventh Framework Program ERC Advanced Grant agreement no. 294099 (erc.europa.eu) to SM; Comunidad de Madrid and EU Marie Curie COFUND program (FP7) 291820 (mvisionconsortium.org/) to NB; Ministerio de Economia y Competitividad Grant FIS2014-56643-R (www.mineco.gob.es) to SM; Ministerio de Economia y Competitividad Grant FIS2013-49544-EXP (www.mineco.gob.es) to CD; Ministerio de Economia y Competitividad FPI Fellowship BES-2015-072197 (www.idi.mineco.gob.es) to AdlH.Peer Reviewe
Global compliance with hepatitis b vaccine birth dose and factors related to timely schedule. A literature review
Objectives: Identify global barriers for delivery of hepatitis B vaccine birth dose. Methods: A search for cross sectional studies published between January 2001 and December 2017 was conducted using the following Mesh terms: "Vaccination"[Mesh], "Mass Vaccination"[Mesh], "Hepatitis B"[Mesh], "Hepatitis B virus"[Mesh], "Hepatitis B Surface Antigens"[Mesh]. Databases consulted included: PUBMED, SCIELO, EMBASE and BIREME. To evaluate the quality of studies, we used an adapted version of the Newcastle-Ottawa Quality Assessment Scale for cross sectional studies. Results: An initial list of 6,789 articles were generated by the combination of search terms. After reviewing titles and abstracts, they were reduced to 134 for full reading, and 22 studies were included in the barriers analysis. The region with more references was Western Pacific while eastern Mediterranean had the lowest. Being born outside of a health facility and weakness of outreach vaccination service seems to be the most important an cited factors related to underperformance of birth dose delivery. In developed countries, hospital policies on birth dose vaccination was the main factor associated to no vaccintion with the birth dose. Conclusions: New ways to deliver hepatitis B vaccines to neonates being born at home or outside health facilities should be envisaged and applied, if the goal of eliminating perinatal transmission of hepatitis B is to be achieved
PRM18 Review of Administration's Cost Assumption of Rotavirus and Pneumococcal Vaccines Cost-Effectiveness Analyses
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