118,271 research outputs found
Bayesian reconstruction of the cosmological large-scale structure: methodology, inverse algorithms and numerical optimization
We address the inverse problem of cosmic large-scale structure reconstruction
from a Bayesian perspective. For a linear data model, a number of known and
novel reconstruction schemes, which differ in terms of the underlying signal
prior, data likelihood, and numerical inverse extra-regularization schemes are
derived and classified. The Bayesian methodology presented in this paper tries
to unify and extend the following methods: Wiener-filtering, Tikhonov
regularization, Ridge regression, Maximum Entropy, and inverse regularization
techniques. The inverse techniques considered here are the asymptotic
regularization, the Jacobi, Steepest Descent, Newton-Raphson,
Landweber-Fridman, and both linear and non-linear Krylov methods based on
Fletcher-Reeves, Polak-Ribiere, and Hestenes-Stiefel Conjugate Gradients. The
structures of the up-to-date highest-performing algorithms are presented, based
on an operator scheme, which permits one to exploit the power of fast Fourier
transforms. Using such an implementation of the generalized Wiener-filter in
the novel ARGO-software package, the different numerical schemes are
benchmarked with 1-, 2-, and 3-dimensional problems including structured white
and Poissonian noise, data windowing and blurring effects. A novel numerical
Krylov scheme is shown to be superior in terms of performance and fidelity.
These fast inverse methods ultimately will enable the application of sampling
techniques to explore complex joint posterior distributions. We outline how the
space of the dark-matter density field, the peculiar velocity field, and the
power spectrum can jointly be investigated by a Gibbs-sampling process. Such a
method can be applied for the redshift distortions correction of the observed
galaxies and for time-reversal reconstructions of the initial density field.Comment: 40 pages, 11 figure
Diffusion Modeling with Domain-conditioned Prior Guidance for Accelerated MRI and qMRI Reconstruction
This study introduces a novel approach for image reconstruction based on a
diffusion model conditioned on the native data domain. Our method is applied to
multi-coil MRI and quantitative MRI reconstruction, leveraging the
domain-conditioned diffusion model within the frequency and parameter domains.
The prior MRI physics are used as embeddings in the diffusion model, enforcing
data consistency to guide the training and sampling process, characterizing MRI
k-space encoding in MRI reconstruction, and leveraging MR signal modeling for
qMRI reconstruction. Furthermore, a gradient descent optimization is
incorporated into the diffusion steps, enhancing feature learning and improving
denoising. The proposed method demonstrates a significant promise, particularly
for reconstructing images at high acceleration factors. Notably, it maintains
great reconstruction accuracy and efficiency for static and quantitative MRI
reconstruction across diverse anatomical structures. Beyond its immediate
applications, this method provides potential generalization capability, making
it adaptable to inverse problems across various domains
Accelerated High-Resolution Photoacoustic Tomography via Compressed Sensing
Current 3D photoacoustic tomography (PAT) systems offer either high image
quality or high frame rates but are not able to deliver high spatial and
temporal resolution simultaneously, which limits their ability to image dynamic
processes in living tissue. A particular example is the planar Fabry-Perot (FP)
scanner, which yields high-resolution images but takes several minutes to
sequentially map the photoacoustic field on the sensor plane, point-by-point.
However, as the spatio-temporal complexity of many absorbing tissue structures
is rather low, the data recorded in such a conventional, regularly sampled
fashion is often highly redundant. We demonstrate that combining variational
image reconstruction methods using spatial sparsity constraints with the
development of novel PAT acquisition systems capable of sub-sampling the
acoustic wave field can dramatically increase the acquisition speed while
maintaining a good spatial resolution: First, we describe and model two general
spatial sub-sampling schemes. Then, we discuss how to implement them using the
FP scanner and demonstrate the potential of these novel compressed sensing PAT
devices through simulated data from a realistic numerical phantom and through
measured data from a dynamic experimental phantom as well as from in-vivo
experiments. Our results show that images with good spatial resolution and
contrast can be obtained from highly sub-sampled PAT data if variational image
reconstruction methods that describe the tissues structures with suitable
sparsity-constraints are used. In particular, we examine the use of total
variation regularization enhanced by Bregman iterations. These novel
reconstruction strategies offer new opportunities to dramatically increase the
acquisition speed of PAT scanners that employ point-by-point sequential
scanning as well as reducing the channel count of parallelized schemes that use
detector arrays.Comment: submitted to "Physics in Medicine and Biology
Building Proteins in a Day: Efficient 3D Molecular Reconstruction
Discovering the 3D atomic structure of molecules such as proteins and viruses
is a fundamental research problem in biology and medicine. Electron
Cryomicroscopy (Cryo-EM) is a promising vision-based technique for structure
estimation which attempts to reconstruct 3D structures from 2D images. This
paper addresses the challenging problem of 3D reconstruction from 2D Cryo-EM
images. A new framework for estimation is introduced which relies on modern
stochastic optimization techniques to scale to large datasets. We also
introduce a novel technique which reduces the cost of evaluating the objective
function during optimization by over five orders or magnitude. The net result
is an approach capable of estimating 3D molecular structure from large scale
datasets in about a day on a single workstation.Comment: To be presented at IEEE Conference on Computer Vision and Pattern
Recognition (CVPR) 201
On sparsity averaging
Recent developments in Carrillo et al. (2012) and Carrillo et al. (2013)
introduced a novel regularization method for compressive imaging in the context
of compressed sensing with coherent redundant dictionaries. The approach relies
on the observation that natural images exhibit strong average sparsity over
multiple coherent frames. The associated reconstruction algorithm, based on an
analysis prior and a reweighted scheme, is dubbed Sparsity Averaging
Reweighted Analysis (SARA). We review these advances and extend associated
simulations establishing the superiority of SARA to regularization methods
based on sparsity in a single frame, for a generic spread spectrum acquisition
and for a Fourier acquisition of particular interest in radio astronomy.Comment: 4 pages, 3 figures, Proceedings of 10th International Conference on
Sampling Theory and Applications (SampTA), Code available at
https://github.com/basp-group/sopt, Full journal letter available at
http://arxiv.org/abs/arXiv:1208.233
High-throughput intensity diffraction tomography with a computational microscope
We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model, featuring slice-wise phase and absorption transfer functions using angled illumination. This new framework facilitates flexible and efficient data acquisition, enabling arbitrary sampling of the illumination angles. The reconstruction algorithm performs 3D synthetic aperture using a robust, computation and memory efficient slice-wise deconvolution to achieve resolution up to the incoherent limit. We demonstrate our technique with thick biological samples having both sparse 3D structures and dense cell clusters. We further investigate the limitation of our technique when imaging strongly scattering samples. Imaging performance and the influence of multiple scattering is evaluated using a 3D sample consisting of stacked phase and absorption resolution targets. This computational microscopy system is directly built on a standard commercial microscope with a simple LED array source add-on, and promises broad applications by leveraging the ubiquitous microscopy platforms with minimal hardware modifications
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