Low-cost wearable sensor based on a D-shaped plastic optical fiber for respiration monitoring

A low cost, wearable textile-based respiratory sensing system is proposed and experimentally demonstrated. A highly sensitive D-shaped plastic optical fiber (POF) sensor that responds to bending is integrated into an elastic band structure to form a respiratory sensing system. The curvature sensing experiments were conducted on the D-shaped POF sensor, which has a coefficient of determination (R2) of 0.9977. The system can be used to monitor not only the respiratory rate (RR) of the human body under different movement states (resting, walking and running), but also the RR of steady and unsteady respiratory signals due to different physiological states. In addition, using the proposed signal processing technique, the interference of motion noise can be removed and the influence of body movement on the sensor response can be eliminated. The advantages of the system are its low cost, compactness and simplicity in design. Thus, the application of the proposed respiratory sensing system provides a simple and inexpensive optical solution for wearable health

Biosensors for Diagnosis and Monitoring

Biosensor technologies have received a great amount of interest in recent decades, and this has especially been the case in recent years due to the health alert caused by the COVID-19 pandemic. The sensor platform market has grown in recent decades, and the COVID-19 outbreak has led to an increase in the demand for home diagnostics and point-of-care systems. With the evolution of biosensor technology towards portable platforms with a lower cost on-site analysis and a rapid selective and sensitive response, a larger market has opened up for this technology. The evolution of biosensor systems has the opportunity to change classic analysis towards real-time and in situ detection systems, with platforms such as point-of-care and wearables as well as implantable sensors to decentralize chemical and biological analysis, thus reducing industrial and medical costs. This book is dedicated to all the research related to biosensor technologies. Reviews, perspective articles, and research articles in different biosensing areas such as wearable sensors, point-of-care platforms, and pathogen detection for biomedical applications as well as environmental monitoring will introduce the reader to these relevant topics. This book is aimed at scientists and professionals working in the field of biosensors and also provides essential knowledge for students who want to enter the field

Review of fiber-optic pressure sensors for biomedical and biomechanical applications

As optical fibers revolutionize the way data is carried in telecommunications, the same is happening in the world of sensing. Fiber-optic sensors (FOS) rely on the principle of changing the properties of light that propagate in the fiber due to the effect of a specific physical or chemical parameter. We demonstrate the potentialities of this sensing concept to assess pressure in biomedical and biomechanical applications. FOSs are introduced after an overview of conventional sensors that are being used in the field. Pointing out their limitations, particularly as minimally invasive sensors, is also the starting point to argue FOSs are an alternative or a substitution technology. Even so, this technology will be more or less effective depending on the efforts to present more affordable turnkey solutions and peer-reviewed papers reporting in vivo experiments and clinical trials.info:eu-repo/semantics/publishedVersio

Sensing Systems for Respiration Monitoring: A Technical Systematic Review

Respiratory monitoring is essential in sleep studies, sport training, patient monitoring, or health at work, among other applications. This paper presents a comprehensive systematic review of respiration sensing systems. After several systematic searches in scientific repositories, the 198 most relevant papers in this field were analyzed in detail. Different items were examined: sensing technique and sensor, respiration parameter, sensor location and size, general system setup, communication protocol, processing station, energy autonomy and power consumption, sensor validation, processing algorithm, performance evaluation, and analysis software. As a result, several trends and the remaining research challenges of respiration sensors were identified. Long-term evaluations and usability tests should be performed. Researchers designed custom experiments to validate the sensing systems, making it difficult to compare results. Therefore, another challenge is to have a common validation framework to fairly compare sensor performance. The implementation of energy-saving strategies, the incorporation of energy harvesting techniques, the calculation of volume parameters of breathing, or the effective integration of respiration sensors into clothing are other remaining research efforts. Addressing these and other challenges outlined in the paper is a required step to obtain a feasible, robust, affordable, and unobtrusive respiration sensing system

MR fully compatible and safe FBG breathing sensor: A practical solution for respiratory triggering

This publication describes an original simple low-cost MR fully-compatible and safe fiber-optic breathing sensor (FOBS), which can be used for respiratory triggering and for monitoring the development of respiratory rate within the MR environment and can, thus, serve as prevention from the hyperventilation syndrome. The sensor is created by encapsulation of the Bragg grating into conventional nasal oxygen cannulas. The sensor is immune to minor patient movements, thus limiting movement artifacts to a minimum. Thanks to this fact it can be used for the retrospective/prospective respiratory gating. The sensor is immune to electromagnetic interference (EMI) and can thus be used in any magnetic field (1.5T, 3T, and 7T). The sensor prototype has been tested in both laboratory and real magnetic resonance (3T) environments relative to conventional pneumatic respiration references (PRR). The data measured were statistically evaluated using the objective Bland-Altman method (BAM) and the functionality of the proposed solution was confirmed. Respiratory Triggering functionality was confirmed by the radiologic doctors on the basis of analyzing images using the most used respiratory triggered T2 TSE 3D sequences and by objective method using the Blind/Referenceless Image Spatial Quality Evaluator (BRISQUE).Web of Science712302512301

Contribución al diseño de sensores vestibles y ambientales para medir la respiración y el salto vertical en adultos mayores y frágiles.

Con el avance de la tecnología, se ha popularizado entre la población el uso de dispositivos para medir su estado de salud. Para lograr esto, se suelen utilizar dispositivos vestibles como los smartwatch y smartbands, dispositivos ambientales embebidos en los alrededores, e incluso dispositivos conectados a aplicaciones móviles. El uso de estas tecnologías también se ha popularizado entre los profesionales de la salud.Esta tesis se centra en el desarrollo de dispositivos para monitorizar la salud de adultos mayores y adultos frágiles. Se desarrollaron dos líneas de trabajo: en la primera se diseñó e implementó un sistema vestible para monitorizar en tiempo real la respiración de los usuarios; en la segunda se desarrolló un sistema ambiental capaz de medir la altura del salto vertical efectuado por los usuarios sobre él.Sistema vestible para monitorizar la respiración:- Dentro de esta línea de trabajo se investigó un nuevo sensor de respiración que venía a cubrir algunas lagunas existentes en el estado de la técnica: la integración de todos los elementos electrónicos del sistema en un encapsulado compacto, la liberación del diseño para su reutilización y mejora por parte de otros investigadores y el bajo coste de los elementos que componen el sistema, entre otros. El sistema vestible consiste en un dispositivo que se coloca alrededor del pecho mediante una cinta ajustable. Este sistema funciona mediante un sensor piezoresistivo que detecta las variaciones en el diámetro del pecho ocasionadas al inhalar y exhalar; las variaciones detectadas son enviadas de forma inalámbrica mediante Bluetooth a una estación de visualización elegida por el usuario (PC, Tablet o Smartphone). El sistema se encuentra embebido en un armazón impreso en 3D. Para validar el funcionamiento de este sistema, se realizaron pruebas con 21 voluntarios que efectuaron diferentes ritmos de respiración. Para obtener los ritmos respiratorios de cada señal generada, se utilizaron dos algoritmos. Estos algoritmos calculan el ritmo respiratorio al segmentar la señal original en ventanas de tiempo desde 6 hasta 30 segundos. Los resultados obtenidos muestran que, con una ventana de tiempo de 27 segundos, se obtiene el menor error para cada algoritmo (4,02% y 3,40 %).Sistema ambiental para medir el salto vertical:- Dentro de esta segunda línea de trabajo se investigó en un novedoso sistema ambiental para medir la altura del salto, lo que supuso una innovación respecto a los sensores utilizados actualmente para este fin. El sistema ambiental consiste en una plataforma que detecta objetos sobre ella mediante la presión, y mide el tiempo transcurrido desde que un objeto se retira y se coloca de nuevo. El sistema detecta los objetos mediante una matriz de sensores piezoresitivos (Force Sensitive Resistors - FSR realizados con velostat). Las dimensiones de la plataforma son 30 cm x 30 cm, área sobre la cual se distribuyen un total de 256 sensores FSR. El salto vertical se calcula mediante la fórmula de tiempo de vuelo, y el resultado es enviado mediante Bluetooth a un PC o Smartphone. Se realizaron dos experimentos: en el primero participaron un total de 38 voluntarios, con el objetivo de validar el funcionamiento del sistema con una cámara de alta velocidad como referencia (120 fps); en el segundo experimento se capturaron los datos en crudo de 15 voluntarios, con estos datos se emularon 10 frecuencias de muestreo (desde 20 Hz hasta 200 Hz) y se analizaron los efectos de utilizar frecuencias más bajas. Del primer experimento se obtuvo un error relativo medio de 1.98% con un coeficiente de determinación r2= 0,996. Del segundo experimento se determinó que las frecuencias de muestreo de 200 Hz y 100 Hz muestran un desempeño similar al mantener un error relativo por debajo del 5% en el 95% de las mediciones.Finalmente, este trabajo de tesis concluye indicando las principales aportaciones realizadas para cada una de las dos líneas de trabajo, así como el trabajo futuro que podría desarrollarse en cada una de ellas.<br /

DEVELOPMENT OF PIEZOELECTRIC SENSORS AND METHODOLOGY FOR NONINVASIVE SIMULTANEOUS DETECTION OF MULTIPLE VITAL SIGNS

The activity of piezoelectric material linked the applied electric field with the strain generated that can be translated into geometrical variations. Flexible steel substrate exhibits fascinating mechanical properties which enable their integration into the emerging field of flexible microelectronics. This work presents an extended technique based on capacitance-voltage dependency to extract the geometrical variations in thin-film piezoelectric materials deposited on a flexible steel. A 50 μm flexible steel sheet has been sandwiched by two PZT film layers, each of 2.4 μm in thickness deposited by sputtering. An aluminum layer of 370 nm has been deposited above each PZT layer to form the electrical contact. The steel sheet represents the common electrode for both PZT structures. Gamry references 3000 analyzers were used to collect the capacitance-voltage measurements then estimating the piezoelectric charge constant. Experimental work has been validated by implementing the same method on a bulk piezoelectric film. Results have shown that the measured capacitance varies by 1% due to dielectric constant voltage dependency. On the other hand, 99% of capacitance variations depend on the change in physical dimensions of the sample via the piezoelectric effect. Further to that, this thesis explores the utilization of piezoelectric-based sensors to collect a corresponding representative signal from the chest surface. The subject typically needs to hold his or her breath to eliminate the respiration effect. This work further contributes to the extraction of the corresponding representative vital signs directly from the measured respiration signal. The contraction and expansion of the heart muscles, as well as the respiration activities, will induce a mechanical vibration across the chest wall. This vibration can be converted into an electrical output voltage via piezoelectric sensors. During breathing, the measured voltage signal is composed of the cardiac cycle activities modulated along with the respiratory cycle activity. The proposed technique employs the principles of piezoelectric and signal-processing methods to extract the corresponding signal of cardiac cycle activities from a breathing signal measured in real-time. All the results were validated step by step by a conventional apparatus, with good agreement observed

Sensores em fibra ótica para o estudo biomecânico do disco intervertebral

Doutoramento em Engenharia MecânicaO presente trabalho teve como objetivo principal estudar o comportamento mecânico do disco intervertebral recorrendo a sensores em fibra ótica. Na expetativa de efetuar o melhor enquadramento do tema foi efetuada uma revisão exaustiva das várias configurações de sensores em fibra ótica que têm vindo a ser utilizadas em aplicações biomédicas e biomecânicas, nomeadamente para medição de temperatura, deformação, força e pressão. Nesse âmbito, procurou-se destacar as potencialidades dos sensores em fibra ótica e apresentá-los como uma tecnologia alternativa ou até de substituição das tecnologias associadas a sensores convencionais. Tendo em vista a aplicação de sensores em fibra ótica no estudo do comportamento do disco intervertebral efetuou-se também uma revisão exaustiva da coluna vertebral e, particularmente, do conceito de unidade funcional. A par de uma descrição anatómica e funcional centrada no disco intervertebral, vértebras adjacentes e ligamentos espinais foram ainda destacadas as suas propriedades mecânicas e descritos os procedimentos mais usuais no estudo dessas propriedades. A componente experimental do presente trabalho descreve um conjunto de experiências efetuadas com unidades funcionais cadavéricas utilizando sensores convencionais e sensores em fibra ótica com vista à medição da deformação do disco intervertebral sob cargas compressivas uniaxiais. Inclui ainda a medição in vivo da pressão intradiscal num disco lombar de uma ovelha sob efeito de anestesia. Para esse efeito utilizou-se um sensor comercial em fibra ótica e desenvolveu-se a respetiva unidade de interrogação. Finalmente apresenta-se os resultados da investigação em curso que tem como objetivo propor e desenvolver protótipos de sensores em fibra ótica para aplicações biomédicas e biomecânicas. Nesse sentido, são apresentadas duas soluções de sensores interferométricos para medição da pressão em fluídos corporais.The present work aimed to study the mechanical behavior of the intervertebral disc using fiber optic sensors. To address the theme an exhaustive review of the various configurations of fiber optic sensors that have been used in biomechanical and biomedical applications, in particular for measuring temperature, strain, force and pressure, was conducted. In this context, an effort was made to highlight the advantages of fiber optic sensors and present them as an alternative or even a substitution technology to conventional sensors. In view of the application of fiber optic sensors to study intervertebral disc behavior an exhaustive review of the spine and, particularly, of the spinal motion segment was made. Along with an anatomical and functional description of the intervertebral disc, the adjacent vertebrae and spinal ligaments, their mechanical properties were also highlighted as well as the most common procedures and guidelines followed in the study of these properties. The experimental section of the present work describes a set of tests performed with cadaveric spinal motion segments using conventional and fiber optic sensors to assess strain of the intervertebral disc under uniaxial compressive loads. This section also includes an experience reporting in vivo pressures measured in the lumbar disc of a sheep under general anesthesia. In this case, a commercial fiber optic sensor and a purpose-built interrogation unit were used. Finally, the results of ongoing research aiming to develop fiber optic sensors prototypes for biomedical and biomechanical applications are presented. Thus, the proof of concept of two possible interferometric configurations intended for pressure measurement in body fluids was presented