77 research outputs found

    Biosensors and CMOS Interface Circuits

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    abstract: Analysing and measuring of biological or biochemical processes are of utmost importance for medical, biological and biotechnological applications. Point of care diagnostic system, composing of biosensors, have promising applications for providing cheap, accurate and portable diagnosis. Owing to these expanding medical applications and advances made by semiconductor industry biosensors have seen a tremendous growth in the past few decades. Also emergence of microfluidics and non-invasive biosensing applications are other marker propellers. Analyzing biological signals using transducers is difficult due to the challenges in interfacing an electronic system to the biological environment. Detection limit, detection time, dynamic range, specificity to the analyte, sensitivity and reliability of these devices are some of the challenges in developing and integrating these devices. Significant amount of research in the field of biosensors has been focused on improving the design, fabrication process and their integration with microfluidics to address these challenges. This work presents new techniques, design and systems to improve the interface between the electronic system and the biological environment. This dissertation uses CMOS circuit design to improve the reliability of these devices. Also this work addresses the challenges in designing the electronic system used for processing the output of the transducer, which converts biological signal into electronic signal.Dissertation/ThesisM.S. Electrical Engineering 201

    Adaptation in Standard CMOS Processes with Floating Gate Structures and Techniques

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    We apply adaptation into ordinary circuits and systems to achieve high performance, high quality results. Mismatch in manufactured VLSI devices has been the main limiting factor in quality for many analog and mixed-signal designs. Traditional compensation methods are generally costly. A few examples include enlarging the device size, averaging signals, and trimming with laser. By applying floating gate adaptation to standard CMOS circuits, we demonstrate here that we are able to trim CMOS comparator offset to a precision of 0.7mV, reduce CMOS image sensor fixed-pattern noise power by a factor of 100, and achieve 5.8 effective number of bits (ENOB) in a 6-bit flash analog-to-digital converter (ADC) operating at 750MHz. The adaptive circuits generally exhibit special features in addition to an improved performance. These special features are generally beyond the capabilities of traditional CMOS design approaches and they open exciting opportunities in novel circuit designs. Specifically, the adaptive comparator has the ability to store an accurate arbitrary offset, the image sensor can be set up to memorize previously captured scenes like a human retina, and the ADC can be configured to adapt to the incoming analog signal distribution and perform an efficient signal conversion that minimizes distortion and maximizes output entropy

    KAVUAKA: a low-power application-specific processor architecture for digital hearing aids

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    The power consumption of digital hearing aids is very restricted due to their small physical size and the available hardware resources for signal processing are limited. However, there is a demand for more processing performance to make future hearing aids more useful and smarter. Future hearing aids should be able to detect, localize, and recognize target speakers in complex acoustic environments to further improve the speech intelligibility of the individual hearing aid user. Computationally intensive algorithms are required for this task. To maintain acceptable battery life, the hearing aid processing architecture must be highly optimized for extremely low-power consumption and high processing performance.The integration of application-specific instruction-set processors (ASIPs) into hearing aids enables a wide range of architectural customizations to meet the stringent power consumption and performance requirements. In this thesis, the application-specific hearing aid processor KAVUAKA is presented, which is customized and optimized with state-of-the-art hearing aid algorithms such as speaker localization, noise reduction, beamforming algorithms, and speech recognition. Specialized and application-specific instructions are designed and added to the baseline instruction set architecture (ISA). Among the major contributions are a multiply-accumulate (MAC) unit for real- and complex-valued numbers, architectures for power reduction during register accesses, co-processors and a low-latency audio interface. With the proposed MAC architecture, the KAVUAKA processor requires 16 % less cycles for the computation of a 128-point fast Fourier transform (FFT) compared to related programmable digital signal processors. The power consumption during register file accesses is decreased by 6 %to 17 % with isolation and by-pass techniques. The hardware-induced audio latency is 34 %lower compared to related audio interfaces for frame size of 64 samples.The final hearing aid system-on-chip (SoC) with four KAVUAKA processor cores and ten co-processors is integrated as an application-specific integrated circuit (ASIC) using a 40 nm low-power technology. The die size is 3.6 mm2. Each of the processors and co-processors contains individual customizations and hardware features with a varying datapath width between 24-bit to 64-bit. The core area of the 64-bit processor configuration is 0.134 mm2. The processors are organized in two clusters that share memory, an audio interface, co-processors and serial interfaces. The average power consumption at a clock speed of 10 MHz is 2.4 mW for SoC and 0.6 mW for the 64-bit processor.Case studies with four reference hearing aid algorithms are used to present and evaluate the proposed hardware architectures and optimizations. The program code for each processor and co-processor is generated and optimized with evolutionary algorithms for operation merging,instruction scheduling and register allocation. The KAVUAKA processor architecture is com-pared to related processor architectures in terms of processing performance, average power consumption, and silicon area requirements

    Ultra-low power mixed-signal frontend for wearable EEGs

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    Electronics circuits are ubiquitous in daily life, aided by advancements in the chip design industry, leading to miniaturised solutions for typical day to day problems. One of the critical healthcare areas helped by this advancement in technology is electroencephalography (EEG). EEG is a non-invasive method of tracking a person's brain waves, and a crucial tool in several healthcare contexts, including epilepsy and sleep disorders. Current ambulatory EEG systems still suffer from limitations that affect their usability. Furthermore, many patients admitted to emergency departments (ED) for a neurological disorder like altered mental status or seizures, would remain undiagnosed hours to days after admission, which leads to an elevated rate of death compared to other conditions. Conducting a thorough EEG monitoring in early-stage could prevent further damage to the brain and avoid high mortality. But lack of portability and ease of access results in a long wait time for the prescribed patients. All real signals are analogue in nature, including brainwaves sensed by EEG systems. For converting the EEG signal into digital for further processing, a truly wearable EEG has to have an analogue mixed-signal front-end (AFE). This research aims to define the specifications for building a custom AFE for the EEG recording and use that to review the suitability of the architectures available in the literature. Another critical task is to provide new architectures that can meet the developed specifications for EEG monitoring and can be used in epilepsy diagnosis, sleep monitoring, drowsiness detection and depression study. The thesis starts with a preview on EEG technology and available methods of brainwaves recording. It further expands to design requirements for the AFE, with a discussion about critical issues that need resolving. Three new continuous-time capacitive feedback chopped amplifier designs are proposed. A novel calibration loop for setting the accurate value for a pseudo-resistor, which is a crucial block in the proposed topology, is also discussed. This pseudoresistor calibration loop achieved the resistor variation of under 8.25%. The thesis also presents a new design of a curvature corrected bandgap, as well as a novel DDA based fourth-order Sallen-Key filter. A modified sensor frontend architecture is then proposed, along with a detailed analysis of its implementation. Measurement results of the AFE are finally presented. The AFE consumed a total power of 3.2A (including ADC, amplifier, filter, and current generation circuitry) with the overall integrated input-referred noise of 0.87V-rms in the frequency band of 0.5-50Hz. Measurement results confirmed that only the proposed AFE achieved all defined specifications for the wearable EEG system with the smallest power consumption than state-of-art architectures that meet few but not all specifications. The AFE also achieved a CMRR of 131.62dB, which is higher than any studied architectures.Open Acces

    Low-power CMOS digital-pixel Imagers for high-speed uncooled PbSe IR applications

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    This PhD dissertation describes the research and development of a new low-cost medium wavelength infrared MWIR monolithic imager technology for high-speed uncooled industrial applications. It takes the baton on the latest technological advances in the field of vapour phase deposition (VPD) PbSe-based medium wavelength IR (MWIR) detection accomplished by the industrial partner NIT S.L., adding fundamental knowledge on the investigation of novel VLSI analog and mixed-signal design techniques at circuit and system levels for the development of the readout integrated device attached to the detector. The work supports on the hypothesis that, by the use of the preceding design techniques, current standard inexpensive CMOS technologies fulfill all operational requirements of the VPD PbSe detector in terms of connectivity, reliability, functionality and scalability to integrate the device. The resulting monolithic PbSe-CMOS camera must consume very low power, operate at kHz frequencies, exhibit good uniformity and fit the CMOS read-out active pixels in the compact pitch of the focal plane, all while addressing the particular characteristics of the MWIR detector: high dark-to-signal ratios, large input parasitic capacitance values and remarkable mismatching in PbSe integration. In order to achieve these demands, this thesis proposes null inter-pixel crosstalk vision sensor architectures based on a digital-only focal plane array (FPA) of configurable pixel sensors. Each digital pixel sensor (DPS) cell is equipped with fast communication modules, self-biasing, offset cancellation, analog-to-digital converter (ADC) and fixed pattern noise (FPN) correction. In-pixel power consumption is minimized by the use of comprehensive MOSFET subthreshold operation. The main aim is to potentiate the integration of PbSe-based infra-red (IR)-image sensing technologies so as to widen its use, not only in distinct scenarios, but also at different stages of PbSe-CMOS integration maturity. For this purpose, we posit to investigate a comprehensive set of functional blocks distributed in two parallel approaches: • Frame-based “Smart” MWIR imaging based on new DPS circuit topologies with gain and offset FPN correction capabilities. This research line exploits the detector pitch to offer fully-digital programmability at pixel level and complete functionality with input parasitic capacitance compensation and internal frame memory. • Frame-free “Compact”-pitch MWIR vision based on a novel DPS lossless analog integrator and configurable temporal difference, combined with asynchronous communication protocols inside the focal plane. This strategy is conceived to allow extensive pitch compaction and readout speed increase by the suppression of in-pixel digital filtering, and the use of dynamic bandwidth allocation in each pixel of the FPA. In order make the electrical validation of first prototypes independent of the expensive PbSe deposition processes at wafer level, investigation is extended as well to the development of affordable sensor emulation strategies and integrated test platforms specifically oriented to image read-out integrated circuits. DPS cells, imagers and test chips have been fabricated and characterized in standard 0.15μm 1P6M, 0.35μm 2P4M and 2.5μm 2P1M CMOS technologies, all as part of research projects with industrial partnership. The research has led to the first high-speed uncooled frame-based IR quantum imager monolithically fabricated in a standard VLSI CMOS technology, and has given rise to the Tachyon series [1], a new line of commercial IR cameras used in real-time industrial, environmental and transportation control systems. The frame-free architectures investigated in this work represent a firm step forward to push further pixel pitch and system bandwidth up to the limits imposed by the evolving PbSe detector in future generations of the device.La present tesi doctoral descriu la recerca i el desenvolupament d'una nova tecnologia monolítica d'imatgeria infraroja de longitud d'ona mitja (MWIR), no refrigerada i de baix cost, per a usos industrials d'alta velocitat. El treball pren el relleu dels últims avenços assolits pel soci industrial NIT S.L. en el camp dels detectors MWIR de PbSe depositats en fase vapor (VPD), afegint-hi coneixement fonamental en la investigació de noves tècniques de disseny de circuits VLSI analògics i mixtes pel desenvolupament del dispositiu integrat de lectura unit al detector pixelat. Es parteix de la hipòtesi que, mitjançant l'ús de les esmentades tècniques de disseny, les tecnologies CMOS estàndard satisfan tots els requeriments operacionals del detector VPD PbSe respecte a connectivitat, fiabilitat, funcionalitat i escalabilitat per integrar de forma econòmica el dispositiu. La càmera PbSe-CMOS resultant ha de consumir molt baixa potència, operar a freqüències de kHz, exhibir bona uniformitat, i encabir els píxels actius CMOS de lectura en el pitch compacte del pla focal de la imatge, tot atenent a les particulars característiques del detector: altes relacions de corrent d'obscuritat a senyal, elevats valors de capacitat paràsita a l'entrada i dispersions importants en el procés de fabricació. Amb la finalitat de complir amb els requisits previs, es proposen arquitectures de sensors de visió de molt baix acoblament interpíxel basades en l'ús d'una matriu de pla focal (FPA) de píxels actius exclusivament digitals. Cada píxel sensor digital (DPS) està equipat amb mòduls de comunicació d'alta velocitat, autopolarització, cancel·lació de l'offset, conversió analògica-digital (ADC) i correcció del soroll de patró fixe (FPN). El consum en cada cel·la es minimitza fent un ús exhaustiu del MOSFET operant en subllindar. L'objectiu últim és potenciar la integració de les tecnologies de sensat d'imatge infraroja (IR) basades en PbSe per expandir-ne el seu ús, no només a diferents escenaris, sinó també en diferents estadis de maduresa de la integració PbSe-CMOS. En aquest sentit, es proposa investigar un conjunt complet de blocs funcionals distribuïts en dos enfocs paral·lels: - Dispositius d'imatgeria MWIR "Smart" basats en frames utilitzant noves topologies de circuit DPS amb correcció de l'FPN en guany i offset. Aquesta línia de recerca exprimeix el pitch del detector per oferir una programabilitat completament digital a nivell de píxel i plena funcionalitat amb compensació de la capacitat paràsita d'entrada i memòria interna de fotograma. - Dispositius de visió MWIR "Compact"-pitch "frame-free" en base a un novedós esquema d'integració analògica en el DPS i diferenciació temporal configurable, combinats amb protocols de comunicació asíncrons dins del pla focal. Aquesta estratègia es concep per permetre una alta compactació del pitch i un increment de la velocitat de lectura, mitjançant la supressió del filtrat digital intern i l'assignació dinàmica de l'ample de banda a cada píxel de l'FPA. Per tal d'independitzar la validació elèctrica dels primers prototips respecte a costosos processos de deposició del PbSe sensor a nivell d'oblia, la recerca s'amplia també al desenvolupament de noves estratègies d'emulació del detector d'IR i plataformes de test integrades especialment orientades a circuits integrats de lectura d'imatge. Cel·les DPS, dispositius d'imatge i xips de test s'han fabricat i caracteritzat, respectivament, en tecnologies CMOS estàndard 0.15 micres 1P6M, 0.35 micres 2P4M i 2.5 micres 2P1M, tots dins el marc de projectes de recerca amb socis industrials. Aquest treball ha conduït a la fabricació del primer dispositiu quàntic d'imatgeria IR d'alta velocitat, no refrigerat, basat en frames, i monolíticament fabricat en tecnologia VLSI CMOS estàndard, i ha donat lloc a Tachyon, una nova línia de càmeres IR comercials emprades en sistemes de control industrial, mediambiental i de transport en temps real.Postprint (published version

    Security Aspects of Printed Electronics Applications

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    Gedruckte Elektronik (Printed Electronics (PE)) ist eine neu aufkommende Technologie welche komplementär zu konventioneller Elektronik eingesetzt wird. Dessen einzigartigen Merkmale führten zu einen starken Anstieg von Marktanteilen, welche 2010 \$6 Milliarden betrugen, \$41 Milliarden in 2019 und in 2027 geschätzt \$153 Milliarden. Gedruckte Elektronik kombiniert additive Technologien mit funktionalen Tinten um elektronische Komponenten aus verschiedenen Materialien direkt am Verwendungsort, kosteneffizient und umweltfreundlich herzustellen. Die dabei verwendeten Substrate können flexibel, leicht, transparent, großflächig oder implantierbar sein. Dadurch können mit gedruckter Elektronik (noch) visionäre Anwendungen wie Smart-Packaging, elektronische Einmalprodukte, Smart Labels oder digitale Haut realisiert werden. Um den Fortschritt von gedruckten Elektronik-Technologien voranzutreiben, basierten die meisten Optimierungen hauptsächlich auf der Erhöhung von Produktionsausbeute, Reliabilität und Performance. Jedoch wurde auch die Bedeutung von Sicherheitsaspekten von Hardware-Plattformen in den letzten Jahren immer mehr in den Vordergrund gerückt. Da realisierte Anwendungen in gedruckter Elektronik vitale Funktionalitäten bereitstellen können, die sensible Nutzerdaten beinhalten, wie zum Beispiel in implantierten Geräten und intelligenten Pflastern zur Gesundheitsüberwachung, führen Sicherheitsmängel und fehlendes Produktvertrauen in der Herstellungskette zu teils ernsten und schwerwiegenden Problemen. Des Weiteren, wegen den charakteristischen Merkmalen von gedruckter Elektronik, wie zum Beispiel additive Herstellungsverfahren, hohe Strukturgröße, wenige Schichten und begrenzten Produktionsschritten, ist gedruckte Hardware schon per se anfällig für hardware-basierte Attacken wie Reverse-Engineering, Produktfälschung und Hardware-Trojanern. Darüber hinaus ist die Adoption von Gegenmaßnahmen aus konventionellen Technologien unpassend und ineffizient, da solche zu extremen Mehraufwänden in der kostengünstigen Fertigung von gedruckter Elektronik führen würden. Aus diesem Grund liefert diese Arbeit eine Technologie-spezifische Bewertung von Bedrohungen auf der Hardware-Ebene und dessen Gegenmaßnahmen in der Form von Ressourcen-beschränkten Hardware-Primitiven, um die Produktionskette und Funktionalitäten von gedruckter Elektronik-Anwendungen zu schützen. Der erste Beitrag dieser Dissertation ist ein vorgeschlagener Ansatz um gedruckte Physical Unclonable Functions (pPUF) zu entwerfen, welche Sicherheitsschlüssel bereitstellen um mehrere sicherheitsrelevante Gegenmaßnahmen wie Authentifizierung und Fingerabdrücke zu ermöglichen. Zusätzlich optimieren wir die multi-bit pPUF-Designs um den Flächenbedarf eines 16-bit-Schlüssels-Generators um 31\% zu verringern. Außerdem entwickeln wir ein Analyse-Framework basierend auf Monte Carlo-Simulationen für pPUFs, mit welchem wir Simulationen und Herstellungs-basierte Analysen durchführen können. Unsere Ergebnisse haben gezeigt, dass die pPUFs die notwendigen Eigenschaften besitzen um erfolgreich als Sicherheitsanwendung eingesetzt zu werden, wie Einzigartigkeit der Signatur und ausreichende Robustheit. Der Betrieb der gedruckten pPUFs war möglich bis zu sehr geringen Betriebsspannungen von nur 0.5 V. Im zweiten Beitrag dieser Arbeit stellen wir einen kompakten Entwurf eines gedruckten physikalischen Zufallsgenerator vor (True Random Number Generator (pTRNG)), welcher unvorhersehbare Schlüssel für kryptographische Funktionen und zufälligen "Authentication Challenges" generieren kann. Der pTRNG Entwurf verbessert Prozess-Variationen unter Verwendung von einer Anpassungsmethode von gedruckten Widerständen, ermöglicht durch die individuelle Konfigurierbarkeit von gedruckten Schaltungen, um die generierten Bits nur von Zufallsrauschen abhängig zu machen, und damit ein echtes Zufallsverhalten zu erhalten. Die Simulationsergebnisse legen nahe, dass die gesamten Prozessvariationen des TRNGs um das 110-fache verbessert werden, und der zufallsgenerierte Bitstream der TRNGs die "National Institute of Standards and Technology Statistical Test Suit"-Tests bestanden hat. Auch hier können wir nachweisen, dass die Betriebsspannungen der TRNGs von mehreren Volt zu nur 0.5 V lagen, wie unsere Charakterisierungsergebnisse der hergestellten TRNGs aufgezeigt haben. Der dritte Beitrag dieser Dissertation ist die Beschreibung der einzigartigen Merkmale von Schaltungsentwurf und Herstellung von gedruckter Elektronik, welche sehr verschieden zu konventionellen Technologien ist, und dadurch eine neuartige Reverse-Engineering (RE)-Methode notwendig macht. Hierfür stellen wir eine robuste RE-Methode vor, welche auf Supervised-Learning-Algorithmen für gedruckte Schaltungen basiert, um die Vulnerabilität gegenüber RE-Attacken zu demonstrieren. Die RE-Ergebnisse zeigen, dass die vorgestellte RE-Methode auf zahlreiche gedruckte Schaltungen ohne viel Komplexität oder teure Werkzeuge angewandt werden kann. Der letzte Beitrag dieser Arbeit ist ein vorgeschlagenes Konzept für eine "one-time programmable" gedruckte Look-up Table (pLUT), welche beliebige digitale Funktionen realisieren kann und Gegenmaßnahmen unterstützt wie Camouflaging, Split-Manufacturing und Watermarking um Attacken auf der Hardware-Ebene zu verhindern. Ein Vergleich des vorgeschlagenen pLUT-Konzepts mit existierenden Lösungen hat gezeigt, dass die pLUT weniger Flächen-bedarf, geringere worst-case Verzögerungszeiten und Leistungsverbrauch hat. Um die Konfigurierbarkeit der vorgestellten pLUT zu verifizieren, wurde es simuliert, hergestellt und programmiert mittels Tintenstrahl-gedruckter elektrisch leitfähiger Tinte um erfolgreich Logik-Gatter wie XNOR, XOR und AND zu realisieren. Die Simulation und Charakterisierungsergebnisse haben die erfolgreiche Funktionalität der pLUT bei Betriebsspannungen von nur 1 V belegt

    Integrated Circuits for Programming Flash Memories in Portable Applications

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    Smart devices such as smart grids, smart home devices, etc. are infrastructure systems that connect the world around us more than before. These devices can communicate with each other and help us manage our environment. This concept is called the Internet of Things (IoT). Not many smart nodes exist that are both low-power and programmable. Floating-gate (FG) transistors could be used to create adaptive sensor nodes by providing programmable bias currents. FG transistors are mostly used in digital applications like Flash memories. However, FG transistors can be used in analog applications, too. Unfortunately, due to the expensive infrastructure required for programming these transistors, they have not been economical to be used in portable applications. In this work, we present low-power approaches to programming FG transistors which make them a good candidate to be employed in future wireless sensor nodes and portable systems. First, we focus on the design of low-power circuits which can be used in programming the FG transistors such as high-voltage charge pumps, low-drop-out regulators, and voltage reference cells. Then, to achieve the goal of reducing the power consumption in programmable sensor nodes and reducing the programming infrastructure, we present a method to program FG transistors using negative voltages. We also present charge-pump structures to generate the necessary negative voltages for programming in this new configuration
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