The very large G-protein coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles

Sensory hair bundles in the inner ear are composed of stereocilia that can be interconnected by a variety of different link types, including tip links, horizontal top connectors, shaft connectors, and ankle links. The ankle link antigen is an epitope specifically associated with ankle links and the calycal processes of photoreceptors in chicks. Mass spectrometry and immunoblotting were used to identify this antigen as the avian ortholog of the very large G-protein-coupled receptor VLGR1, the product of the Usher syndrome USH2C (Mass1) locus. Like ankle links, Vlgr1 is expressed transiently around the base of developing hair bundles in mice. Ankle links fail to form in the cochleae of mice carrying a targeted mutation in Vlgr1 (Vlgr1/del7TM), and the bundles become disorganized just after birth. FM1-43 [N-(3-triethylammonium)propyl)-4-(4-(dibutylamino)styryl) pyridinium dibromide] dye loading and whole-cell recordings indicate mechanotransduction is impaired in cochlear, but not vestibular, hair cells of early postnatal Vlgr1/del7TM mutant mice. Auditory brainstem recordings and distortion product measurements indicate that these mice are severely deaf by the third week of life. Hair cells from the basal half of the cochlea are lost in 2-month-old Vlgr1/del7TM mice, and retinal function is mildly abnormal in aged mutants. Our results indicate that Vlgr1 is required for formation of the ankle link complex and the normal development of cochlear hair bundles

Aldebaran's angular diameter: how well do we know it?

The bright, well-known K5 giant Aldebaran, alpha Tau, is probably the star with the largest number of direct angular diameter determinations, achieved over a long time by several authors using various techniques. In spite of this wealth of data, or perhaps as a direct result of it, there is not a very good agreement on a single angular diameter value. This is particularly unsettling if one considers that Aldebaran is also used as a primary calibrator for some angular resolution methods, notably for optical and infrared long baseline interferometry. Directly connected to Aldebaran's angular diameter and its uncertainties is its effective temperature, which also has been used for several empirical calibrations. Among the proposed explanations for the elusiveness of an accurate determination of the angular diameter of Aldebaran are the possibility of temporal variations as well as a possible dependence of the angular diameter on the wavelength. We present here a few, very accurate new determinations obtained by means of lunar occultations and long baseline interferometry. We derive an average value of 19.96+-0.03 milliarcseconds for the uniform disk diameter. The corresponding limb-darkened value is 20.58+-0.03 milliarcseconds, or 44.2+-0.9 R(sun). We discuss this result, in connection with previous determinations and with possible problems that may affect such measurements.Comment: 8 pages, 4 figures, accepted for publication in A&

The Coevality of Young Binary Systems

Multiple star systems are commonly assumed to form coevally; they thus provide the anchor for most calibrations of stellar evolutionary models. In this paper we study the binary population of the Taurus-Auriga association, using the component positions in an HR diagram in order to quantify the frequency and degree of coevality in young binary systems. After identifying and rejecting the systems that are known to be affected by systematic errors (due to further multiplicity or obscuration by circumstellar material), we find that the relative binary ages, |Delta log(tau)|, have an overall dispersion of sigma~0.40 dex. Random pairs of Taurus members are coeval only to within sigma~0.58 dex, indicating that Taurus binaries are indeed more coeval than the association as a whole. However, the distribution of |Delta log(tau)| suggests two populations, with ~2/3 of the sample appearing coeval to within the errors (sigma~0.16 dex) and the other ~1/3 distributed in an extended tail reaching |Delta log(tau)|~0.4-0.9 dex. To explain the finding of a multi-peaked distribution, we suggest that the tail of the differential age distribution includes unrecognized hierarchical multiples, stars seen in scattered light, or stars with disk contamination; additional followup is required to rule out or correct for these explanations. The relative coevality of binary systems does not depend significantly on the system mass, mass ratio, or separation. Indeed, any pair of Taurus members wider than ~10' (~0.7 pc) shows the full age spread of the association.Comment: 23 pages, 11 figures; accepted to Ap

How large should whales be?

The evolution and distribution of species body sizes for terrestrial mammals is well-explained by a macroevolutionary tradeoff between short-term selective advantages and long-term extinction risks from increased species body size, unfolding above the 2g minimum size induced by thermoregulation in air. Here, we consider whether this same tradeoff, formalized as a constrained convection-reaction-diffusion system, can also explain the sizes of fully aquatic mammals, which have not previously been considered. By replacing the terrestrial minimum with a pelagic one, at roughly 7000g, the terrestrial mammal tradeoff model accurately predicts, with no tunable parameters, the observed body masses of all extant cetacean species, including the 175,000,000g Blue Whale. This strong agreement between theory and data suggests that a universal macroevolutionary tradeoff governs body size evolution for all mammals, regardless of their habitat. The dramatic sizes of cetaceans can thus be attributed mainly to the increased convective heat loss is water, which shifts the species size distribution upward and pushes its right tail into ranges inaccessible to terrestrial mammals. Under this macroevolutionary tradeoff, the largest expected species occurs where the rate at which smaller-bodied species move up into large-bodied niches approximately equals the rate at which extinction removes them.Comment: 7 pages, 3 figures, 2 data table

Evolutionary models for low-mass stars and brown dwarfs: uncertainties and limits at very young ages

We analyse pre-Main Sequence evolutionary tracks for low mass stars with masses m \le 1.4 \msol based on the Baraffe et al. (1998) input physics. We also extend the recent Chabrier et al. (2000) evolutionary models based on dusty atmosphere to young brown dwarfs down to one mass of Jupiter. We analyse current theoretical uncertainties due to molecular line lists, convection and initial conditions. Simple tests on initial conditions show the high uncertainties of models at ages \simle 1 Myr. We find a significant sensitivity of atmosphere profiles to the treatment of convection at low gravity and \te < 4000 K, whereas it vanishes as gravity increases. This effect adds another source of uncertainty on evolutionary tracks at very early phases. We show that at low surface gravity (\log g \simle 3.5,) the common picture of vertical Hayashi lines with constant \te is oversimplified. The effect of a variation of initial deuterium abundance is studied. We compare our models with evolutionary tracks available in the literature and discuss the main differences. We finally analyse to which extent current observations of young systems provide a good test for pre-Main Sequence tracks.Comment: 12 pages, Latex file, uses aa.cls, accepted for publication in A&

HST/STIS observations of the RW Aurigae bipolar jet: mapping the physical parameters close to the source

We present the results of new spectral diagnostic investigations applied to high-resolution long-slit spectra of the RW Aur bipolar jet obtained with HST/STIS. The spectra include the forbidden doublets [O I] 6300,6363 \AA, [S II] 6716,6731 \AA, and [N II] 6548, 6583 \AA that we utilized to determine electron density, electron temperature, hydrogen ionisation fraction, total hydrogen density, radial velocity and the mass outflow rate. We were able to extract the parameters as far as 3".9 in the red- and 2".1 in the blueshifted beam. The RW Aur jet appears to be the second densest outflow from a T Tauri star studied so far, but its other properties are quite similar to those found in other jets from young stars. The overall trend of the physical parameters along the first few arcseconds of the RW Aur jet is similar to that of HH 30 and DG Tau and this can reflect analogies in the mechanisms operating in that region, suggesting the same engine is accelerating the jets in the T Tauri stars with outflows. Our study of the RW Aur jet indicates for the first time that, despite the detected marked asymmetries in physical and kinematic properties between the two lobes, the mass outflow rates in the two lobes are similar. This appears to indicate that the central engine has constraining symmetries on both sides of the system, and that the observed asymmetries are probably due to different environmental conditions.Comment: 24 pages, 10 figures, accepted for publication in the Astronomy and Astrophysic

A Test of Pre-Main Sequence Evolutionary Models Across the Stellar/Substellar Boundary Based on Spectra of the Young Quadruple GG Tau

We present spatially separated optical spectra of the components of the young hierarchical quadruple GG Tau. Spectra of GG Tau Aa and Ab (separation 0".25 ~ 35 AU) were obtained with the Faint Object Spectrograph aboard the Hubble Space Telescope. Spectra of GG Tau Ba and Bb (separation 1".48 ~ 207 AU) were obtained with both the HIRES and the LRIS spectrographs on the W. M. Keck telescopes. The components of this mini-cluster, which span a wide range in spectral type (K7 - M7), are used to test both evolutionary models and the temperature scale for very young, low mass stars under the assumption of coeval formation. Of the evolutionary models tested, those of Baraffe et al. (1998, A&A, 337, 403) yield the most consistent ages when combined with a temperature scale intermediate between that of dwarfs and giants. The version of the Baraffe et al. models computed with a mixing length nearly twice the pressure scale height is of particular interest as it predicts masses for GG Tau Aa and Ab that are in agreement with their dynamical mass estimate. Using this evolutionary model and a coeval (at 1.5 Myrs) temperature scale, we find that the coldest component of the GG Tau system, GG Tau Bb, is substellar with a mass of 0.044 +/- 0.006 Msun. This brown dwarf companion is especially intriguing as it shows signatures of accretion, although this accretion is not likely to alter its mass significantly. GG Tau Bb is currently the lowest mass, spectroscopically confirmed companion to a T Tauri star, and is one of the coldest, lowest mass T Tauri objects in the Taurus-Auriga star forming region.Comment: 25 pages, 6 figures, accepted for publication in The Astrophysical Journa