Seedling Establishment of Spartina alterniflora and Spartina patens on Dredged Materials in Texas

Effects of fertilizer, elevation, and tidal inundation on seedling establishment of Spartina alterniflora and Spartina patens were tested at a wave-protected sandy dredged material site, Galveston Bay, Texas. No seedlings that grew from sown seeds became established at elevations below 36 cm (msl) while the greatest number established in the upper tier. Seedlings of S. alterniflora were more numerous than S. patens in the upper and middle tiers. Naturally occurring seedlings of S. alterniflora, which apparently germinated from seeds produced on transplants in adjacent plots, established at all elevations of the site during winter. The average time of tidal inundation at a particular elevation was less during winter than spring. Thus, establishment of plants by seed at low intertidal elevations appears feasible only during low seasonal winter tides and with S. alterniflora. Fertilizers did not enhance growth, and high concentrations of fertilizer caused stress to some S. alterniflora seedlings

Higgs Boson Studies at the Tevatron

We combine searches by the CDF and D0 Collaborations for the standard model Higgs boson with mass in the range 90--200 GeV$/c^2$ produced in the gluon-gluon fusion, $WH$, $ZH$, $t{\bar{t}}H$, and vector boson fusion processes, and decaying in the $H\rightarrow b{\bar{b}}$, $H\rightarrow W^+W^-$, $H\rightarrow ZZ$, $H\rightarrow\tau^+\tau^-$, and $H\rightarrow \gamma\gamma$ modes. The data correspond to integrated luminosities of up to 10 fb$^{-1}$ and were collected at the Fermilab Tevatron in $p{\bar{p}}$ collisions at $\sqrt{s}=1.96$ TeV. The searches are also interpreted in the context of fermiophobic and fourth generation models. We observe a significant excess of events in the mass range between 115 and 140 GeV/$c^2$. The local significance corresponds to 3.0 standard deviations at $m_H=125$ GeV/$c^2$, consistent with the mass of the Higgs boson observed at the LHC, and we expect a local significance of 1.9 standard deviations. We separately combine searches for $H \to b\bar{b}$, $H \to W^+W^-$, $H\rightarrow\tau^+\tau^-$, and $H\rightarrow\gamma\gamma$. The observed signal strengths in all channels are consistent with the presence of a standard model Higgs boson with a mass of 125 GeV/$c^2$

LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis

Contains fulltext : 177057.pdf (publisher's version ) (Closed access)A genome-wide association study identified LMO1, which encodes an LIM-domain-only transcriptional cofactor, as a neuroblastoma susceptibility gene that functions as an oncogene in high-risk neuroblastoma. Here we show that dbetah promoter-mediated expression of LMO1 in zebrafish synergizes with MYCN to increase the proliferation of hyperplastic sympathoadrenal precursor cells, leading to a reduced latency and increased penetrance of neuroblastomagenesis. The transgenic expression of LMO1 also promoted hematogenous dissemination and distant metastasis, which was linked to neuroblastoma cell invasion and migration, and elevated expression levels of genes affecting tumor cell-extracellular matrix interaction, including loxl3, itga2b, itga3, and itga5. Our results provide in vivo validation of LMO1 as an important oncogene that promotes neuroblastoma initiation, progression, and widespread metastatic dissemination