2,094 research outputs found
Some Effects of Extreme Shortening on Frog Skeletal Muscle
We have established that the sarcolemma of frog skeletal muscle is so firmly tied in at each sarcomere level near the M line, as well as near the Z line, that it is thrown into folds or festoons when the fibers shorten. The attachment is not broken even when the fibers shorten to 25% of optimum tension length. Such extreme shortening affects both the morphology and physiology of the muscle; the morphological change seems to be limited to the myofilaments. The physiological effects in frog sartorius muscle include an increase in resting oxygen consumption and changes in the relation between fiber length and isometric tension similar to those found in isolated muscle fibers
Intrinsic hole mobility and trapping in a regio-regular poly(thiophene)
The transport properties of high-performance thin-film transistors (TFT) made
with a regio-regular poly(thiophene) semiconductor (PQT-12) are reported. The
room-temperature field-effect mobility of the devices varied between 0.004
cm2/V s and 0.1 cm2/V s and was controlled through thermal processing of the
material, which modified the structural order. The transport properties of TFTs
were studied as a function of temperature. The field-effect mobility is
thermally activated in all films at T<200 K and the activation energy depends
on the charge density in the channel. The experimental data is compared to
theoretical models for transport, and we argue that a model based on the
existence of a mobility edge and an exponential distribution of traps provides
the best interpretation of the data. The differences in room-temperature
mobility are attributed to different widths of the shallow localized state
distribution at the edge of the valence band due to structural disorder in the
film. The free carrier mobility of the mobile states in the ordered regions of
the film is the same in all structural modifications and is estimated to be
between 1 and 4 cm2/V s.Comment: 20 pages, 8 figure
Oxidative phosphorylation. Halide-dependent and halide-independent effects of triorganotin and trioganolead compounds on mitochondrial functions
Erosive Wear Characterization of Materials for Lunar Construction
NASA s Apollo missions revealed that exhaust from the retrorockets of landing spacecraft may act to significantly accelerate lunar dust on the surface of the Moon. A recent study by Immer et al. (C. Immer, P.T. Metzger, P.E. Hintze, A. Nick, and R. Horan, Apollo 12 Lunar Module exhaust plume impingement on Lunar Surveyor III, Icarus, Vol. 211, pp. 1089-1102, 2011) investigated coupons returned to Earth from the Surveyor III lunar probe which were subjected to lunar dust impingement by the Apollo 12 Lunar Module landing. Their study revealed that even with indirect impingement, the spacecraft sustained erosive damage from the fast-moving lunar dust particles. In this work, results are presented from a series of erosive wear experiments performed on 6061 Aluminum using the JSC-1AF lunar dust simulant. Optical profilometry was used to investigate the surface after the erosion process. It was found that even short durations of lunar dust simulant impacting at low velocities produced substantial changes in the surface
"Kicking Up Some Dust": An Experimental Investigation Relating Lunar Dust Erosive Wear to Solar Power Loss
The exhaust from retrograde rockets fired by spacecraft landing on the Moon can accelerate lunar dust particles to high velocities. Information obtained from NASA's Apollo 12 mission confirmed that these high-speed dust particles can erode nearby structures. This erosive wear damage can affect the performance of optical components such as solar concentrators. Solar concentrators are objects which collect sunlight over large areas and focus the light into smaller areas for purposes such as heating and energy production. In this work, laboratory-scale solar concentrators were constructed and subjected to erosive wear by the JSC-1AF lunar dust simulant. The concentrators were focused on a photovoltaic cell and the degradation in electrical power due to the erosive wear was measured. It was observed that even moderate exposure to erosive wear from lunar dust simulant resulted in a 40 percent reduction in power production from the solar concentrators
Ab initio estimate of temperature dependence of electrical conductivity in a model amorphous material: hydrogenated amorphous silicon
We present an ab initio calculation of the DC conductivity of amorphous
silicon and hydrogenated amorphous silicon. The Kubo-Greenwood formula is used
to obtain the DC conductivity, by thermal averaging over extended dynamical
simulation. Its application to disordered solids is discussed. The conductivity
is computed for a wide range of temperatures and doping is explored in a naive
way by shifting the Fermi level. We observed the Meyer-Neldel rule for the
electrical conductivity with E_MNR = 0.06 eV and a temperature coefficient of
resistance, TCR ~ -2.0% K^-1 for a-Si:H. In general, experimental trends are
reproduced by these calculations, and this suggests the possible utility of the
approach for modeling carrier transport in other disordered systems.Comment: 9 pages, 8 figures, submitted to PRB Comments: corrected typos,
referee's comments include
Detection of (1,3)-β-d-Glucan in Cerebrospinal Fluid in Histoplasma Meningitis
The diagnosis of central nervous system (CNS) histoplasmosis is often difficult. Although cerebrospinal fluid (CSF) (1,3)-β-d-glucan (BDG) is available as a biological marker for the diagnosis of fungal meningitis, there are limited data on its use for the diagnosis of Histoplasma meningitis. We evaluated CSF BDG detection, using the Fungitell assay, in patients with CNS histoplasmosis and controls. A total of 47 cases and 153 controls were identified. The control group included 13 patients with a CNS fungal infection other than histoplasmosis. Forty-nine percent of patients with CNS histoplasmosis and 43.8% of controls were immunocompromised. The median CSF BDG level was 85 pg/ml for cases, compared to <31 pg/ml for all controls (P < 0.05) and 82 pg/ml for controls with other causes of fungal meningitis (P = 0.27). The sensitivity for detection of BDG in CSF was 53.2%, whereas the specificity was 86.9% versus all controls and 46% versus other CNS fungal infections. CSF BDG levels of ≥80 pg/ml are neither sensitive nor specific to support a diagnosis of Histoplasma meningitis
RoboTAP: Target priorities for robotic microlensing observations
Context. The ability to automatically select scientifically-important transient events from an alert stream of many such events, and to conduct follow-up observations in response, will become increasingly important in astronomy. With wide-angle time domain surveys pushing to fainter limiting magnitudes, the capability to follow-up on transient alerts far exceeds our follow-up telescope resources, and effective target prioritization becomes essential. The RoboNet-II microlensing program is a pathfinder project, which has developed an automated target selection process (RoboTAP) for gravitational microlensing events, which are observed in real time using the Las Cumbres Observatory telescope network.
Aims. Follow-up telescopes typically have a much smaller field of view compared to surveys, therefore the most promising microlensing events must be automatically selected at any given time from an annual sample exceeding 2000 events. The main challenge is to select between events with a high planet detection sensitivity, with the aim of detecting many planets and characterizing planetary anomalies.
Methods. Our target selection algorithm is a hybrid system based on estimates of the planet detection zones around a microlens. It follows automatic anomaly alerts and respects the expected survey coverage of specific events.
Results. We introduce the RoboTAP algorithm, whose purpose is to select and prioritize microlensing events with high sensitivity to planetary companions. In this work, we determine the planet sensitivity of the RoboNet follow-up program and provide a working example of how a broker can be designed for a real-life transient science program conducting follow-up observations in response to alerts; we explore the issues that will confront similar programs being developed for the Large Synoptic Survey Telescope (LSST) and other time domain surveys
Electron Spin for Classical Information Processing: A Brief Survey of Spin-Based Logic Devices, Gates and Circuits
In electronics, information has been traditionally stored, processed and
communicated using an electron's charge. This paradigm is increasingly turning
out to be energy-inefficient, because movement of charge within an
information-processing device invariably causes current flow and an associated
dissipation. Replacing charge with the "spin" of an electron to encode
information may eliminate much of this dissipation and lead to more
energy-efficient "green electronics". This realization has spurred significant
research in spintronic devices and circuits where spin either directly acts as
the physical variable for hosting information or augments the role of charge.
In this review article, we discuss and elucidate some of these ideas, and
highlight their strengths and weaknesses. Many of them can potentially reduce
energy dissipation significantly, but unfortunately are error-prone and
unreliable. Moreover, there are serious obstacles to their technological
implementation that may be difficult to overcome in the near term.
This review addresses three constructs: (1) single devices or binary switches
that can be constituents of Boolean logic gates for digital information
processing, (2) complete gates that are capable of performing specific Boolean
logic operations, and (3) combinational circuits or architectures (equivalent
to many gates working in unison) that are capable of performing universal
computation.Comment: Topical Revie
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