10 research outputs found
Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)
- Author
- A Hemadasa N.
- Abadia-Forcen M. T.
- Abawi L.
- Abd-Elsalam S.
- Abdallah H.
- Abdel-Elsalam W.
- Abdelkarim M.
- Abdelsaid K Abdul Aal Y.
- Abdul S. R.
- Abdulmula A.
- Aboazamazem H.
- Aboelkhair A.
- Aboulqasim I.
- Abusannuga M.
- Acosta Buitrago L. M.
- Adekoya A.
- Adepoju O.
- Adeyeye A.
- Adeyeye A.
- Adeyeye A.
- Adi H.
- Adu-Peprah E.
- Aeed M.
- Afzal A.
- Afzal M.
- Agrawal M. K.
- Agresta F.
- Aguayo J. C.
- Aguirre N.
- Ahari D.
- Ahari D.
- Ahmad A.
- Ahmed A.
- Ahmed M.
- Ahmed Mohammed Al-Mahdi S.
- Ahmed W.
- Ahmed W. U.
- Ahn J. H.
- Aizza G.
- Akhter Rahman M. M.
- Akinmade A.
- Al Athath S.
- Al Dahabrh S.
- Al Gasi A. E. J.
- Al Madhloum Al Suwaidi F.
- Al Shafie A.
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- Al-Ameri S.
- Al-Ardah M.
- Al-Naggar H.
- Al-Naggar H.
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- Alalawi Y.
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- Albashri M.
- Alberts V.
- Albirnawi H.
- Alcaraz A.
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- Aldenfria A.
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- Aleksic L.
- Alexandrou A.
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- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Get PDFBackground: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
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- Publication date
- 18/01/2024
- Field of study
No full textThe impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y.
- Abad-Gurumeta A.
- Abad-Motos A.
- Abadia M.
- Abassy J.
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
Get PDFThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery
Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)
- Author
- A Hemadasa N.
- Abadía-Forcen M. T.
- Abawi L.
- Abd-Elsalam S.
- Abdallah H.
- Abdel-Elsalam W.
- Abdelkarim M.
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- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
No full textBackground: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
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- Özçelik M.F.
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- Şanli A.N.
- Publication venue
- Publication date
- 01/01/2024
- Field of study
No full textBackground: Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods: The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results: A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion: Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Isaac John
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- Ntirenganya Faustin
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- Owen H
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- Papadopoulos V
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- Pockney P
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- Ângelo M
- Älgå A
- Çelebi F
- Çolak E
- Öfner D
- Öhlberger L
- Özant A
- Özçay N
- Öğücü H
- Überrück L
- Ćoza I
- Ławnicka A
- Žatecký J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
Get PDFAimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Global Incidence and Risk Factors Associated With Postoperative Urinary Retention Following Elective Inguinal Hernia Repair
- Author
- Ali
- A. Rady Ahmed Hassan
- Aamir Faiqa B.
- Ababneh Hazim Sameer Mohammad
- Abaidalla Ahmed Faraj
- Abd Al-Fattah Mohammed
- Abd El-razik Sally Ahmed
- Abdelfattah Mohamed S.
- Abdelgalil Mahmoud Shaban
- Abdelhaleem Ibrahim A.
- Abdelmageed Abdelfatah A.
- Abdelwahid Elharith H.
- Abdulhamid Salaheddin M.
- Abdullah Areeba
- Abdullah Mohammad A.
- Abdullah Weaam M.
- Abdulmonem Aya Abdulilah
- Abdulwahed Eman A.
- Abelevich Alexander
- Abo Ghanima Shymaa M.
- Abotaleb Khadega
- Abozid Anwaar
- Abu Jayyab Mustafa A.
- Abu Reyash Tamara K.
- Abu-Arish Hamdoon
- Abu-Ismail Luai
- Abubakr Muhammad
- Abufaraj Mohammad
- Abuleil Amro
- Abuzeid Issa A.
- Adesunkanmi Abdul Hafiz O.
- Adeyeye Ademola Adetoyese
- Adinolfi Elvira
- Adwin Zainal Z.
- Afeikhena Ehis
- Agalianos Christos
- Ahmad Abrar
- Ahmad Hasan Y.
- Ahmad Shahzaib
- Ahmad Sharifa
- Ahmed Fathil Ida Nadiah
- Ahmed Samar G.
- Ahmed Shaheer
- Ahonkhai Irele Ifijeh
- Aimon Sibgha
- Aiolfi Alberto
- Ajekwu Samuel Chibuzo
- Aketch Martin Safari
- Akhtar Aamena
- Akhtar Hamza
- Akram Muhammad U.
- Aktas Ahmed
- Al Bastaki Aysha
- AL Hamoud Mohammad A.
- Al Sagheir Eman
- Al Shareeda Mohamad
- Al-Aydi Tala
- Al-Dhaheri Manal Jamal
- Al-Eryani Fatima
- Al-Eryani Salwa
- Al-Hajj Al-Fakih Wadhah Ahmed
- Al-Juaifari Maytham A.
- Al-Kubaisy Manolia
- Al-Nagdy Mohamed
- Al-Naggar Hamza
- Al-Saba'a Yousef K.
- Al-Shami Khayry
- Al-Shehari Mohammed
- AL-Wajeeh Ghadeer
- Alaa Sherif
- Alabad Madian
- Alabd Husayn M.
- Alahmad Ziad
- Alam Mansoor
- Alameen Hind
- Alaniz Alday Maria Jimena
- Alannaz Omar
- Alansary Marwa N.
- Alarabi Rehab
- Alasawdeh Hadeel
- Albaraesi Mohammed N.
- Alberca Páramo Ana
- Alberich Prats Marta
- Aldawoody Hogir I. R.
- Aldressi Wafa
- Alemad Shada
- Alfa Yakubu
- Alghareeb Rafah
- Alhaj Ahmad
- Alharazin Mohammed
- Alhasan Hasan
- Ali Ali
- Ali Ebrahim M.
- Ali Farjad
- Ali Wasaq
- Aliskander Fater
- Aljaber Ahmad
- Aljamal Sarah
- Alkahlout Dana M.
- Alkaseek Akram Mohammed
- Alkomi Saja
- Allen-Brough Chelsea
- Almasarweh Sami A.
- Almokdad Fares Kh.
- Almugaddami Ayman
- Aloulou Mohammad
- Alozai Muhammad Ilyas
- Alqassab Mohammed K.
- AlQatta Wail M.
- Alrayes Bourhan M. H.
- Alsayadi Ramzi
- Alshaikh Bushra Hussein
- Alshareea Entisar
- Alsmail Mohamed H.
- Alsori Mohamed
- Alvarado-Hurtado Ricardo
- Alvarez Cuiñas Ana
- Alvarez-Lozada Luis Adrian
- Alwis Weerakkodige Mithun Chamindaka
- Amer Fatima M.
- Amnaina Mohamed G.
- Anastasi Alessandro
- Andreuccetti Jacopo
- Andrews Emmet
- Anele Christopher Obinna
- Antonaya Rubia Eva
- Antonopoulou Maria Ioanna
- Antropoli Carmine
- Anwar Muhammad Idrees
- Apelian Shant N.
- Aprea Giovanni
- Arbi Fawad M.
- Arnaout Ahmad Y.
- Arnaout Khaled
- Arrambide-Garza Francisco J.
- Arthur Thomas
- Asghar Tofique
- Ashfersh Mohamed
- Asif Aiza
- Askar Aamal
- Asla Amir F.
- Asla Amir Fathi
- Atatra Khalil O.
- Attiya Omar
- Auchterlonie Rowan
- Avellaneda Nicolás L.
- Awad Ahmed K.
- Awadi Sajeda
- Awwad Amjad H.
- Ayaz Ali Amrat
- Azzam Muayad
- Bagaglini Giulia
- Bagrjancev Maxim
- Bahroun Sumayyah G.
- Baili Efstratia
- Bakeer Hibah Bileid
- Bakhtiar Mahnoor
- Balasubramanian Ishwarya
- Baldini Edoardo
- Balla Andrea
- Balluerca Alba María
- Balogun Simon Adewale
- Bandara Ginimal Bandaralage Kavinda Deshapriya
- Bani Hani Mohammad
- Barka Sharf
- Barnes Tracey
- Barry Kevin
- Bashir Muhammed
- Bazaev Andrey
- Bean Orlagh
- Bennett Kathleen E.
- Biala Marwa
- Biancafarina Alessia
- Biel Arrufat Alex
- Bissett Ian P.
- Boccia Olivia
- Boland Michael R.
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- Bona Davide
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- Borreca Riccardo
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- Bouliaris Konstantinos
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- Breen Kieran J.
- Bsisu Isam
- Butt Adam U. A.
- Cagigal Ortega Elima
- Calabrò Marcello
- Camuera González Maite
- Can Şahin Melike Zeynep
- Canonico Giuseppe
- Cantürk Nuh Zafer
- Capolupo Gabriella T.
- Carannante Filippo
- Carganico Giacomo
- Caricato Marco
- Carmignani Francesco
- Carrara Giulia
- Carroll Paul
- Castaldi Antonio
- Cavaliere Davide
- Cervera Celdrán Iria
- Chan Kin Yik
- Charalabopoulos Alexandros
- Chatzimavroudis Grigorios
- Chavarrías Torija Nuria
- Chawla Tabish
- Chong Nicole
- Chrysos Emmanuel
- Chua Irene
- Chubukova Natalia
- Clancy Cillian
- Clarizia Guglielmo
- Clementé Gastón A.
- Coello-González Alejandro
- Coffey Calvin
- Colás-Ruiz Enrique
- Conlon Eoin
- Conneely John B.
- Connelly Tara M.
- Constantine Ezeme
- Cook Holly
- Cooke Fiachra
- Corcione Francesco
- Creavin Ben
- Croghan Stefanie M.
- Dal Nawaz A.
- Daniyan Muhammad
- Danzi Michele
- Dar Kamran H.
- Daradkeh Hamza
- Dardour Mohammad
- Daula Muhammad I. H.
- Davey Matthew G.
- Davis Niall F.
- de la O-Escamilla Manuel E.
- De Luca Marcello
- De Marco Paolino
- De Palma Giovanni Domenico
- De Prizio Marco
- Dean Yomna
- Deeknah Abdulqudus
- Deiana Selene
- Del Castillo Díez Federico
- Demirli Atici Semra
- Dhannoon Amenah
- Di Franco Gregorio
- Diaz Peña Patricia
- Dillon Patrick
- Dominguez Carla M
- Dorovinis Panagiotis
- Durán-Castro Daniela G.
- Durrani Ahmed M.
- Dweik Raghad
- Earley Helen
- Ebada Mahmoud A.
- Edgerton Colston
- Egbuchulem Ifeanyichukwu Kelvin
- Egdeer Amin
- Ekhmaj Reyad
- El Assaad Yousra
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- El kady Abd Elrahman S.
- El Sherpiny Mohamed A.
- El Tahier Abdalla Omer Mohammad
- El-Deeb Amr M.
- El-Mansoury Tarek M.
- El-Taher Ahmed K.
- Elbadawy Merihan A.
- Eldeghedi Maher
- Elfeki Hossam
- Elgadi Tahani
- Elghadban Hosam
- Elhadi Muhammed
- Elhadi Muhammed
- Elhajdawe Fras A. D.
- Elliott Jessie A.
- Elliott Jessie A.
- Elsaadany Reem
- Elsadek Menan A.
- Elsayed Ahmed
- Elshami Mohamedraed
- Eltaeb Khalid F.
- Eltagani Eltahir
- Enjuto Martínez Diego T.
- Erman Myyas N.
- Estraviz- Mateos Begoña
- Ewedah Moataz
- Fabbri Nicolò
- Fahey Brian
- Fakhar Samra
- Fakoya Adegbolahan
- Farag Marina
- Farahat Sherif
- Farhan Emaan
- Farinelli Pablo Alberto
- Farooqui Fareeha
- Fayed Laila
- Fayed Notaila M.
- Fazal Mishaal
- Fazal Talha bin
- Feo Carlo V.
- Fernández-Vega Laura
- Fleming Christina A.
- Fleres Francesco
- Foley Niamh M.
- Fradelos Evangelos
- Frank Amy
- Fullard Anna
- Fullard Anna C.
- Furbetta Niccolò
- Galal-Eldin Sami
- Gallo Gaetano
- Galun Danijel
- García Domínguez Antonio
- García López de Goicoechea David
- Garrahy Darragh
- Garvin Joseph
- Ghaith Hazem S.
- Ghamri Nusr
- Ghanem Maha
- Ghannam Mohammad Maen
- Ghatwary Ahmed M.
- Ghazal Ahmad
- Ghmagh Reem
- Giacaman Yazan
- Gidiem Doaa
- Gil Barrionuevo Marta
- Gil Gomez Vicente
- Gill Sonia
- Ginestal Mariana
- Girardi Martina
- Giraudo Giorgio
- Gjam Fatima Z.
- Gomaty Jamal M.
- Gonzalez Guerreiro Judit
- Gonzalez-De Miguel Melania
- Gortázar de las Casas Sara
- Goya María M.
- Grande Michele
- Grassia Michele
- Grimaldi Luciano
- Grinlinton Megan
- Guadagni Simone
- Guboug Ali
- Guevara Martínez Jenny
- Guldogan Cem E.
- Gundogdu Emre
- Güler Sertaç Ata
- Güner 
- Hai Arrham
- Haider Sohaib
- Haij Manal Zain Mohammed
- Halwani M. Yasser
- Hamdan Alaa
- Hameed Fahd Mudassar
- Hamid Hytham K. S.
- Hanly Ann
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- Nelli Tommaso
- Ng Kin Cheung
- Nigri Giuseppe
- Nikolouzakis Taxiarchis K.
- Novikova Anastastia
- Nugent Emmeline
- null null
- O' Leary Peter D.
- O'Brien Stephen J.
- O'Riordain Michael
- Ogundoyin Olakoyode O
- Olagunju Naomi
- Olaisheh Habib
- Olayinka Mohammed Taofiq
- Omar Mohammed A.
- Omar Osama
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- Oqdeh Yahya F.
- Ortiz Rodriguez Carles
- Osman Osama S.
- Otaky Mohammad Baraa
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- Rashid Haroon
- Ratnayake Milidu V. B.
- Rehman Kiran
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- Ryan Odhran K.
- Saad Aalaa
- Saad Ahmad
- Saad Reem J.
- Sadek Kareem
- Saeed Abdullah B.
- Saeed Reham J. M.
- Sainz-Lete Aitor
- Sakr Ahmad
- Sakr Yara
- Salih Mugahid A.
- Salih Saniye
- Saracoglu Kemal Tolga
- Sarwar Muhammad Zeeshan
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- Shulman Natassia
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- Teker Kenan
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- Teng Roy
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- Thompson-Fawcett Mark W.
- Tolani Musliu Adetola
- Toomey Desmond
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- Toubasi Ahmad A.
- Toum Fthelrahman M.
- Ukrani Ronika Devi
- ul Haq Syed Atif
- Umer Farooq
- Uprak Tevfik Kıvılcım
- Ur Rehman Sheeraz
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- Valderrabano Gonzalez Santiago
- Vallet Fernandez Josep
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- Varghese Chris
- Vázquez-Melero Alba
- Vignati Barbara
- Vigutto Gabriele
- Wang Huaxi
- Waqar Usama
- Weeratunga George
- Winter Des C.
- Winter Des C.
- Wong Benjamin Ngie Xiong
- Xenaki Sofia
- Xu William
- Y. Aljabarein Osama
- Yaghoub Ali Abdulhafiz
- Yang Wah
- Yanishev Alexey
- Yaqoob Sadia
- Yaqub Aimen
- Yasin Fawzi Hesham
- Younes Eman
- Youssef Hadeer M. S.
- Zahid Muhammad
- Zahid Sufian M.
- Zahran Ahmed A. A. A
- Zalf Kamal
- Zarin Mohammad
- Zawahra Aya
- Zayat Hussein
- Zayat Mohammed A.
- Zevallos-Quiroz Julio
- Zheng Helen
- Zivanovic Marko
- Zwain Yasir A.
- Publication venue
- Publication date
- 01/01/2023
- Field of study
No full textImportance Postoperative urinary retention (POUR) is a well-recognized complication of inguinal hernia repair (IHR). A variable incidence of POUR has previously been reported in this context, and contradictory evidence surrounds potential risk factors.Objective To ascertain the incidence of, explore risk factors for, and determine the health service outcomes of POUR following elective IHR.Design, Setting, and Participants The Retention of Urine After Inguinal Hernia Elective Repair (RETAINER I) study, an international, prospective cohort study, recruited participants between March 1 and October 31, 2021. This study was conducted across 209 centers in 32 countries in a consecutive sample of adult patients undergoing elective IHR.Exposure Open or minimally invasive IHR by any surgical technique, under local, neuraxial regional, or general anesthesia.Main Outcomes and Measures The primary outcome was the incidence of POUR following elective IHR. Secondary outcomes were perioperative risk factors, management, clinical consequences, and health service outcomes of POUR. A preoperative International Prostate Symptom Score was measured in male patients.Results In total, 4151 patients (3882 male and 269 female; median [IQR] age, 56 [43-68] years) were studied. Inguinal hernia repair was commenced via an open surgical approach in 82.2% of patients (n = 3414) and minimally invasive surgery in 17.8% (n = 737). The primary form of anesthesia was general in 40.9% of patients (n = 1696), neuraxial regional in 45.8% (n = 1902), and local in 10.7% (n = 446). Postoperative urinary retention occurred in 5.8% of male patients (n = 224), 2.97% of female patients (n = 8), and 9.5% (119 of 1252) of male patients aged 65 years or older. Risk factors for POUR after adjusted analyses included increasing age, anticholinergic medication, history of urinary retention, constipation, out-of-hours surgery, involvement of urinary bladder within the hernia, temporary intraoperative urethral catheterization, and increasing operative duration. Postoperative urinary retention was the primary reason for 27.8% of unplanned day-case surgery admissions (n = 74) and 51.8% of 30-day readmissions (n = 72).Conclusions The findings of this cohort study suggest that 1 in 17 male patients, 1 in 11 male patients aged 65 years or older, and 1 in 34 female patients may develop POUR following IHR. These findings could inform preoperative patient counseling. In addition, awareness of modifiable risk factors may help to identify patients at increased risk of POUR who may benefit from perioperative risk mitigation strategies
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aaqil Shah
- Aaron Sanchez
- Abd Almonem Shaikh Ahmad
- Abdelrahman Shehata
- Abdelrahman Shehata
- Abdul Sillah
- Abdulkader Shaar
- AbdulRahman Sari
- Abdurrahman Abba Sheshe
- Abhishek Samuel
- Abhishek Sharma
- Abida K Sattar
- Abigail Sarmiento
- Abigail Semple
- Abrham Shitaw
- Abu Talha Siddiqui
- Adriana Scamporlino
- Agathe Seguin-Givelet
- Ahmad Sayasneh
- Ahmad Shokry
- Ahmed Elshawadfy Sherif
- Ahmed Emad Sayed Hassan
- Ahmed S Sedik
- Ahmed Samir Farahat
- Ahmed Seleim
- Ahmed Shabana
- Ahmed Shaheen
- Ahmed Shehta
- Ahmed Shirazi
- Ahmet Can Sarı
- Ahmet Necati Sanli
- Ailén Sánchez Cruz
- Aina Serra
- Aisulu Sarmenova
- Ajay Savlania
- Alaa Sharabi
- Alasdair Santini
- Alejandro Sanchez Arteaga
- Alejandro Sanchez Pellejero
- Aleksandar Sekulić
- Alexandra Schwartz
- Alexandra Sharpe
- Alexandra Shlomina
- Alexey Shilyaev
- Ali Samkari
- Ali Shafiee
- Aliaa Shamardal
- Alima Satanova
- Alistair Savage
- Alphonse Marie Sibomana
- Alvaro Eduardo Sánchez Hernández
- Alvaro Sanchez Barrueco
- Aly Sanad
- Amaia Sanz Larrainzar
- Amal Shukri
- Aman Sethi
- Amanda Shen
- Amatallah Hadi Shamsan
- Ami Shah
- Amin Siddig
- Amit Sastry
- Amjad Shah
- Amr Shalaby
- Ana Carolina Scintini Herbst
- Ana Maria Simono Charadan
- Ana Sánchez Gollarte
- Ana Sánchez Mozo
- Ana Senent-Boza
- Anand Sanmugam
- Andrea Sangheli
- Andrea Sanz Llorente
- Andrea Schmedding
- Andrea Simic
- Andreas Scheiwiller
- Andreas Schnitzbauer
- Andreea-Madalina Serban
- Andrei Shulgin
- Andrew Schache
- Andrés Sánchez-Gómez
- Aneela Shaheen
- Angelino Sanna
- Aniqa Shahzad
- Ankit Sarin
- Ann Stephany Sanchez Marmolejos
- Anna Sayers
- Anna Sánchez López
- Anneka Shah
- Anshumala Shukla Kulkarni
- Anton H Schwabegger
- Antonia Schulte
- Antonio Luciano Sarni
- Antonio Mario Scanu
- Antonio Sanchís López
- Antonio Santoro
- Anu Sandhya
- Anushka Sieunarine
- Anwar Sadat Seidu
- Anwar Shamandi
- Arjun Shajpal
- Arnaldo Neves Santos Silva
- Arshad Siddiqui
- Arunkumar Sekar
- Ashish Lal Shrestha
- Ashish Sharma
- Ashleigh Sercombe
- Astad Sidhwa
- Athanasios Saratziotis
- Athanasios Saratzis
- Athish Shetty
- Atif Sharif
- Atsushi Sawada
- Atsushi Seichi
- Aurélien Scalabre
- Ayesha Shaukat
- Aymen Shafqat
- Ayten Saracoglu
- Ayushi Shukla
- Azka Shaheen
- Babak Siavashi
- Balasupramaniam Sathesan
- Balqis Shawer
- Barbara Seeliger
- Barış Sevinç
- Bárbara Segura-Méndez
- Benedikt Schäfer
- Benedikt Schmid
- Benjamin Scott
- Berta Serrano
- Bhaskar Satsangi
- Birte Schmidt
- Blagoj Shuntov
- Blanca Santos
- Bonnie Sheu
- Brasil Silva Neto
- Brooke Short
- Bruno Sensi
- Burmaa Sanjaa
- Bushra Sayeh Mohamed Elhabashi
- Camilo Sandoval
- Can Sarica
- Carlos Ferreira Dos Santos
- Carlos San Miguel
- Carlos Sanchez Rodriguez
- Carlos Santacruz
- Carlos Shiraishi Zapata
- Carmen Emanuela Scandura
- Carmen Siebenhofer
- Catherine Sarre
- Catherine Shaw
- Catriona Shenton
- Chabwera Shumba
- Charlie Saunders
- Cherith Semple
- Christian Schauer
- Christian Schineis
- Christie Hok Yung Shum
- Christoph Schäffer
- Christoph Schmolmüller
- Christopher Scott
- Claire Sharpin
- Clarisa Simon Perez
- Claudia Sarrais Polo
- Claudia Scherl
- Codin Saon
- Concepcion Segura
- Cristian Sandu
- Cristina Sanz
- Cristina Sánchez Del Pueblo
- Cristina Sánchez Torralvo
- Dagim Shimelash
- Dainius Simcikas
- Daleen Shehadeh
- Daniel Sanabria
- Daniel Sanchez-Pelaez
- Daniel Schlager
- Daniel Schöni
- Daniel Selvaraj
- Daniel Serralta de Colsa
- Daniel Shaerf
- Darya Shlyk
- David Selwyn
- Deana Shenaq
- Denise Sievers
- Dennis Serrano
- Débora Schalge Campioto
- Diana Santana
- Diego Samudio
- Diego Sasia
- Diego Schaps
- Dima Simona
- Dimiter Shinkov
- Dimitrios Schizas
- Dimitrios Sfoungaris
- Dimple Sapre
- Divya Sarin
- Djayanti Sari
- Dmitry Shkarupa
- Dmitry Shmatov
- Donald Schweitzer
- Dorien Schneidmueller
- Dr Abhishek Sarkar
- Dr Afroz Satpathy
- Dr Ali Shami
- Dr Ashraf Shoma
- Dr Shweta Shetye
- Dr Zamir Ahmad Shah
- Dragan Serghei
- Duaa Sheikh Kadro
- Edgar Sanz
- Edoardo Segalini
- Ehab Shiban
- Ekaterina Semina
- Eleazar Santana
- Elio Fabio Sánchez Cortés
- Elisa Scarnecchia
- Elisa Sebastiani
- Elise Sarjanoja
- Elva Marita Sarte
- Ema Santos
- Emil Schemitsch
- Emily Shih
- Emma-Tina Segall
- Emmanuel Schneck
- Enrico Sartori
- Erdene Sandag
- Eric Shumba
- Erin Scott
- Erin Sergey
- Ernesto Sánchez Castillo
- Esraa Sayed
- Faaiz Ali Shah
- Fabienne Schochter
- Fabrizio Scognamillo
- Fagun Shah
- Farah Shaheen
- Farakh Shahzad
- Fareed Showqi
- Farokh Savaddar
- Farrukh Ozair Shah
- Fateh Sher
- Fatima Sanchez Cabezudo Noguera
- Fatima Serhan
- Fatima Tuz Zahra Shakir
- Fatma Sefi
- Fátima Sánchez Fernández
- Fátima Sena-Ruiz
- Federica Scolari
- Fernando Sevilla
- Filip Sianos
- Francesca Simonelli
- Francesco Selvaggi
- Franck K Sikakulya
- Françoise Schmitt
- Frederique Sauvat
- Gagandeep Sandhu
- Gary Schwartz
- Georg Scheriau
- Gerald Seitinger
- Getachew Shumye
- Ghada Shalaby
- Ghaidaa Sanjuq
- Gianluca Matteo Sampietro
- Gianmarco Saponaro
- Gilbert Samuel
- Giorgio Saraceno
- Giulia Sedda
- Giulio Santoro
- Giuseppe Sammarco
- Giuseppe Sarpietro
- Giuseppe Sica
- Giuseppe Simone
- Goran Šantak
- Gowthanan Santhirakumaran
- Götz Schmidt
- Gregory Senofsky
- Guido Sciaudone
- Guillermo Alberto Sarmiento Ramirez
- Guillermo Sanchez-Villaseñor
- Gursev Sandlas
- Habie Samuel
- Hafiz Saqib Sikandar
- Hafiz Syed Zaigham Ali Shah
- Haleema Siddique
- Hannah Sellars
- Hany Shoreem
- Harriet Shearman
- Harsha Shanthanna
- Haseeb Seriwala
- Hassan Shaukat
- Helena Silveira
- Helmut Alfredo Segovia Lohse
- Hemant Sheth
- Henry Shapiro
- Herald Rene Segovia Lohse
- Herman Sehmbi
- Hernan Sandoval
- Hijab Siddique
- Hiroyuki Seki
- Hoda Sherif
- Hrishikesh Sarkar
- Hugo Santos-Sousa
- Husam Sarayrah
- Hüsnü Şevi K
- Ian Shyaka
- Ian Simel
- Ifeoluwa Shoyombo
- Ikumi Sawada
- Imraan Sardiwalla
- Imtiaz Ahmed Shakir
- Inderpaul Samra
- Inês Isabel Sampaio da Nóvoa Gomes Miguel
- Ingmar Seiwerth
- Ioannis Sarantitis
- Ioannis Siasios
- Ipsit Shah
- Irena Sesar
- Irena Shiderova
- Irène Santos
- Irvita Sharma
- Isabel Sanchez Cuadrado
- Isabel Simal Badiola
- Isabelle Schmit
- Isaie Sibomana
- Ismael Sedano-Portillo
- Ismail Sert
- Jack Sample
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- Jan Schirnhofer
- Janahan Sarveswaran
- Jasem Seba
- Jaspreet Kaur Seehra
- Javier Sanchez Gonzalez
- Javier Serrano González
- Jean Paul Shumbusho
- Jeancarllo Silva
- Jeannie Shen
- Jenardan Sellathurai
- Jerette Schultz
- Jessica Shoemaker
- Jigar Shah
- Joana San Anton
- Joel Jesús Sánchez Estupiñan
- Johannes Sander
- John Ashutosh Santoshi
- John Sandoval
- Jonathon Sheen
- Jonida Selmani
- Jordán Scherñuk
- Jorge Dos Santos Silva
- Jorge Sancho-Muriel
- Jorge Santos
- Jorge Sanz Romera
- Jos É Santos
- Jose Maria Silva Barandiaran
- Josefin Segelman
- Josep M Segur
- Joseph Sferra
- Joseph Shalhoub
- José Antonio Sánchez Martínez
- José Ignacio Sánchez Méndez
- Joud Shiekhoni
- Joudy Shurbatji
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- Juan Ramón Sanz
- Julia Siebert
- Julie Sanders
- Julie Sijmons
- Justin Gabriel Schlager
- Justina Seyi-Olajide
- Justina Shikongo
- K T Matthew Seah
- Kai Sheng Saw
- Kaitlyn Sharp
- Kalai Shaw
- Kamilla Schmitz Nunes
- Kanesh Kumaran Seevalingam
- Karim Shenit
- Karishma Shah
- Karl Schwaiger
- Kathryn Schaffer
- Kemal Saracoglu
- Kenji Shigemi
- Ketan Shah
- Khaled Sarraf
- Khursheed Ahmed Samo
- Kibruyisfaw Shumbash
- Kiran Sarfraz
- Kirill Shostka
- Kohila Sigamoney
- Kozo Sato
- Kristián Šimko
- Lars Schröder
- Laura Sandland-Taylor
- Laura Sánchez Blasco
- Leonie Siemen
- Lesley Sheach
- Lilian Schwarz
- Liliana Sequeira
- Liliana Silva-Igua
- Lisa Shea
- Lokesh Sasatti
- Lorenzo Scardina
- Lorna Scullion
- Luc Hervé Samison
- Lucio Selvaggi
- Lucy Scott
- Ludmila Sidorova
- Luigi Simonelli
- Luis Sánchez-Guillén
- Madiha Saqib
- Madiha Shahid
- Mafalda Sampaio-Alves
- Mahmoud Mohamed Mohamed Shalaby
- Mahmoud Shaban
- Majd Sheikh Alganameh
- Malin Simlund
- Mamta Shah
- Manaf Sharabaji
- Manjunath Siddaiah-Subramanya
- Maphios Siamuchembu
- Marc-Olivier Sauvain
- Marcello Schiavo
- Marco Sandoval Vaez
- Marco Santos
- Margaret Shi
- Margherita Serra
- Maria Juliana Sanchez
- Maria Serra Guivernau
- Maria Shemetova
- Marián Sedlák
- Marina Sánchez Robles
- Mario Santinami
- Marisa Domingues Santos
- María José Sangüesa
- María Liz Sánchez
- María Sánchez-Rubio
- María Sol Siliato Robles
- María Victoria Simón Sanz
- Mark Seamon
- Mark Simmons
- Marta Santos Espí
- Marta Seid
- Martijn Schoneveld
- Marwah Shilfeet
- Marwan Shorman
- Maryam Sherwani
- Masaki Shiota
- Masamitsu Sanui
- Mat Salleh Sarif
- Mathilde Sarlabous
- Matteo Santoliquido
- Matteo Serenari
- Matthew Sargent
- Matthew Short
- Mauricio Sandoval Tobar
- Md Abu Sayed
- Mee Hoong See
- Melissa Silva
- Mennatallah Sheta
- Mercedes Sanz
- Mert Mahsuni Sevinc
- Michael Sander
- Michael Sander
- Michael Shaw
- Michael Shinkwin
- Miguel Sanfeliu Giner
- Miguel Sánchez Suárez
- Miguel Semião
- Milena Senica Verbic
- Mishary Shalhoub
- Miski Scerif
- Mogahid Sharfeldein
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- Mohamad Shareeda
- Mohamed Nafea Shaar
- Mohamed Sawalem
- Mohamed Serour
- Mohamed Shalaby
- Mohamed Shalaby
- Mohamed Sharshar
- Mohamed Shemeis
- Mohamed Sherief
- Mohamed Shetiwy
- Mohamed Shoukry
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- Monica Serrano-Navidad
- Monira Sarih
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- Sameh Shehata
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- Sana Shagour
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- Sandra Sanz
- Sanjeewa Seneviratne
- Sanket Sadanand Shetty
- Santhosh Kumar Sampengere Annayappa
- Santhosh Shivashankar Chikkanayakanahalli
- Santiago Sánchez-Cabús
- Sara Seegert
- Sarah Shamim
- Sarah Shiels
- Sarah Shream
- Sarbpreet Sarao
- Sari Samman
- Sato Satoshi
- Satyanarayan Sankhwar
- Saurav Sarkar
- Saydash Shamsutdinov
- Sayed Shah Nur Hussein Shah
- Scott Schimpke
- Sean Ezekiel Seow
- Sebastian Shu Yip
- Segun Segun-Busari
- Sena Sefera
- Sera Sarsam
- Seyyed Hossein Shafiei
- Shafaque Shaikh
- Shahila Sheik
- Shahrima Sheefat
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- Shaima Sayad
- Shashank Shekhar
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- Sherief Shawki
- Shigehito Sawamura
- Shilpa Sharma
- Shivakumar Shankar
- Shomik Sengupta
- Sikachov Sergei
- Silvia Santiago Maniega
- Silvia Segattini
- Sissy-Amelie Schulz
- Sivendran Seevanayagam
- Sílvia Silva
- Smruta Shanbhag
- Sohei Satoi
- Srdjan Saso
- Srujan Sharma
- Stefan Schmidbauer
- Stefano Scabini
- Steffen Seyfried
- Stephanie Savage
- Sudip Sanyal
- Sudip Shakya
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- Susannah Shore
- Sushruta Shrivastava
- Suzette Samlalsingh
- Taariq Shaikh
- Taha Ismail Sefrioui
- Taher Sawadi
- Tainá Santos Bezerra
- Takeshi Sasaki
- Tal Shahar
- Tanisha Sharma
- Tanishq Sharma
- Tanveer Shafqat
- Tarik Sammour
- Tariq Azam Siddiqi
- Tatjana Savic Jovanovic
- Teddy Saputra
- Tedesco Silvia
- Thabet Sayed Bakir
- Theodoros Sidiropoulos
- Thiago Henrique Sigoli Pereira
- Thilo Maria Schulte
- Thomas Schroeppel
- Thomas Seisen
- Tin Sein
- Tinashe Shoko
- Tjokorda Gde Agung Senapathi
- Tobias Schaetz
- Tobias Schlesinger
- Tolulope Olayinka Sayomi
- Tomislav Sečan
- Tony Shaju
- Toshiya Shiga
- Ts Shylasree
- Tsuyoshi Sano
- Tunde T Sholadoye
- Ugam Shah
- Umberto Scovazzi
- Ushma Shah
- Usman Siddique
- Valentin Schreiter
- Vanessa Sanchez Torrents
- Vanessa Savopoulos
- Varun Sarodaya
- Vicente Simo
- Victor Santos
- Vijay Sharma
- Vijay Shetty
- Vinay Shah
- Vincenzo Scorcia
- Vinita Sangai
- Vinno Savelli
- Violeta Šetka-Čuljak
- Vlad Silaghi
- Vuk Šćepanović
- Walid Shaban
- Wan Nee Shue
- William Shelker
- Yael Sandler
- Yaron Shargall
- Yashwant Shelke
- Yassmeen Sharafeldin Mohammed
- Yi Th Ng Seow
- Yuri Sekiya
- Zahid Shafiq
- Zain Saqfalhait
- Ziyan Sheng
- Zoe Seymour
- Publication venue
- Publication date
- 01/01/2021
- Field of study
No full textBackground Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population.The aim of this study was to inform vaccination prioritization by modelling the impact of vaccination on elective inpatient surgery. The study found that patients aged at least 70 years needing elective surgery should be prioritized alongside other high-risk groups during early vaccination programmes. Once vaccines are rolled out to younger populations, prioritizing surgical patients is advantageous
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Author
- A Nizarudeen
- Aalem Hajer Abd Alhamed
- Ababneh Hazim
- Abbas Ahmed
- Abbas Aram
- Abbas Hussain
- Abbasi Arezou
- Abbassi Fariba
- Abbasy Jibran
- Abbood Ali H
- Abboud Kirellos
- Abdallah Ahmed
- Abdalsalam Sabriya Juma Ali
- Abdelaal Abdelrahman
- Abdelalemm Mohamed
- Abdelhafez Mohammed Hisham Zayan
- Abdelhalim Karim
- Abdeljalil Mahmoud
- Abdelkarem Mohamed
- Abdelmageed Abdelfatah
- Abdelmageed Abdelfatah
- Abdelmaksoud Mohamed
- Abdelmawgoud Sherif
- Abdelmawla Mohamed
- Abdelmawla Mohamed Osama Mohammed Kamel
- Abdelmoneim Noha
- Abdelnoor Ahmad
- Abdelrahman Fatma
- Abdelrazek Hussein A
- Abdelrhman Reham
- Abdelzaher Abdurrahman
- Abdelzaher Abdurrahman Taha
- Abdou Khaled
- Abdoun Meriem
- Abdualqader Mahmmoud
- Abdualqader Mahmmoud Yehia Mohammed
- Abdulhaq Aram
- Abduljawad Heba
- Abdullaev Abakar
- Abdullah Nik Azim Nik
- Abdulmonem Aya
- Abdulwahed Eman
- Abebrese John
- Abiyere Henry
- Abobakr Abobakr Mahfoz
- Aboelfath Shiamaa
- Abosamak Nour Eldin
- Abu-Elfatth Ahmed Mohammed
- Abu-Ghazal Sara
- Abu-Ghazal Sara Yassir
- Abuali Ahmed S A M E
- Abuelazm Mohamed
- Abuelnaga Yasmeen
- Abuelnaga Yasmeen
- Abughazal Sara Yasser
- Abuleil Amro
- Abusannuga Malek
- Abuzaina Khalil
- Adam Islam
- Aday Ulaş
- Adeyeye Ademola
- Adeyeye Nigeria Ademola
- Adham Mustapha
- Adhikari Krishna Mohan
- Affary Anter Al
- Afzal Ameer
- Afzal Iqraa
- Aghdassi Ali
- Ahmed Emad Ali
- Ahmed Mohamed Bahaa Eldin
- Ahmed Randa
- Ahmeed Sultan
- Ajayi Peter
- Akahoshi Keiichi
- Akbar Ali
- Akhtar Naseem
- Al-Abdi Radfan
- Al-Abed Omar
- Al-Ameri Saba
- Al-Ameri Saba Ahmed Ahmed Saleh
- Al-Asadi Mohammed Abdulkhaleq Mohammed Mohsen
- Al-Dowsh Nagra Are
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- Al-Faiq Siham
- Al-Haj Ahmad
- Al-Hyari Abdelkareem
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- Al-juaifari Maytham Aqeel
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- Al-Shami Khayry
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- Al-sharabi Ebrahim Ahmed Esmail
- Al-Shehari Mohammed
- Al-Tekreeti Sarah
- Alahmed Farouq
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- Alali Mahmoud Bilal
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- Alazab Emad
- Albaba Safa'
- Albakry Rudaina
- Albar Aisha
- Albaraesi Mohammed N
- Albarouni Sofian
- Albishti Ahmed
- Alboridy Muneera
- Aldoescu Sorin
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- Aldressi Wafa
- Aldumaini Hamdan
- Alegria Cesar Rodriguez
- Alfano Marie Sophie
- Alfatah Maryam Abd
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- Oldani Graziano
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- Waqar Usama
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- Wennerblom Johanna Hansson
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- Wierzchowski Michał
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- Windsor John
- Winslow Emily
- Wlazlak Michal
- Wolfgang Christopher
- Wu Chien Hui
- Wu Chien Hui
- Wüllenweber Hans-Peter
- Wyroślak-Najs Justyna
- Yadav Kaushal
- Yadev Induprabha
- Yadev Induprabha
- Yaghan Rami
- Yamamoto Tomohisa
- Yang Po-Chih
- Yassin Laya Moayyad Ahmed
- Yassin Raya
- Yegen Cumhur
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- Yesilyurt Degercan
- Yip Vincent
- Yoong Boon
- Yoong Boon Koon
- Younes Eman
- Younes Eman
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- Yousef Amal
- Youssef Amal
- Yu Ming-Chin
- Zacharakis Emmanouil
- Zacharoulis Dimitrios
- Zachiotis Marinos
- Zagainov Vladimir
- Zaharie Florin
- Zahed Mohamed
- Zahed Mohamed Samir Mohamed
- Zakaria Andee Dzulkarnaen
- Zamri Fatimah Mardhiyyah Binti
- Zanatta Michela
- Zanello Matteo
- Zanini Nicola
- Zanus Giacomo
- Zanus Giacomo
- Zaruba Pavel
- Zawia Ali
- Zayed Ahmed
- Zdujic Predrag
- Zedelj Jurica
- Zeh Herbert J
- Zentar Aziz
- Zerbi Alessandro
- Zidan Taha
- Zidan Taha
- Zironda Andrea
- Zitawi Abdullah
- Zivanovic Marko
- Zogopoulos George
- Zonta Sandro
- Zonta Sandro
- Zorrilla Carlos Florez
- Zozaya Gabriel
- Zreqat Qusai
- Zuhdi Zamri
- Zuhdy Mohammad
- Zygomalas Apollon
- Publication venue
- Publication date
- 01/01/2024
- Field of study
No full textBackground: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide.Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters.Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries.Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761)
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akçay Özlem
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-Díez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado Fabíola
- Amador Cristina García
- Amanullah Nazli
- Amaral Hélida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- Andrés Beatriz Díaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Aşkar Ahmet
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
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- Aybar Engin
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- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
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- Álvarez-Llano Laura
- Ângelo Miguel Duarte
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia Fernández
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
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- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
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- Banham Gail
- Bannoud Mohammad Hassan
- Baños Pedro Antonio Parra
- Baptista Victor
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- Barbalace Nicolas
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- Bareka Metaxia
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- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel Sánchez
- Bayhan Zülfü
- Bayo José Manuel Muros
- Bayón Raquel Álvaro
- Bánky Balázs
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
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- Benjelloun El Bachir
- Benkabbou Amine
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- Bernotaite Vlada
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- Bethune Robert
- Bezede Cosmin
- Beznosenko Andriy
- Bhangu Aneel
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- Bianchi Romina
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- Blanco-Colino Ruth
- Blasco Laura Fraile
- Blazquez-Martin Alma
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- Yılmaz Gülseren
- Yilmazlar Tuncay
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Get PDFBackground
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
