Monitoreo de vibrio spp. en ostiones Crassostrea virginica de las lagunas de Tamiahua y Tampamachoco, Veracruz, México

Vibrio es un género ampliamente distribuído en ambientes estuarinos y marinos, adaptable y con rápida propagación de sus cepas. Los moluscos bivalvos son reservorios potenciales de Vibrios, su consumo está relacionado con el desarrollo de vibriosis leve como gastroenteritis hasta septicemia grave o la muerte. Por lo cual es importante el monitoreo continuo en las áreas de extraccion y distribución para evaluar el riesgo para la salud humana derivado del consumo de moluscos y garantizar la inocuidad de estos bivalvos. En el presente estudio se determinaron las diferencias estacionales en la presencia y abundancia de Vibrios durante las fases de recolección (bancos ostrícolas) y post-recolección (cooperativas y restaurantes) en ostiones Crassostrea virginica de las lagunas de Tamiahua y Tampamachoco, Veracruz, México. Las muestras fueron obtenidas de trece sitios al azar durante el año 2018. El aislamiento bacteriano se realizó por el método de siembra por dilución en medio TCBS y recuento en placa de acuerdo a la NOM-031-SSA1-1993. El análisis estadístico indicó que no existieron diferencias espaciales significativas, no obstante, se presentaron diferencias estacionales. En esta investigación, se evidencia por primera vez, la presencia de Vibrio spp. en ostiones de las cooperativas de estudio. También se reporta la ausencia de este género bacteriano en los restaurantes adyacentes. En general, los resultados muestran la necesidad de aplicar medidas dirigidas a reducir la presencia de Vibrios durante la fase de post-recolección de ostiones, con la finalidad de disminuir el riesgo de infección por Vibrio spp. en los consumidores

Estructura poblacional de la captura del ostión Crassostrea virginica en las lagunas de Tamiahua y Tampamachoco, Veracruz, México

The objective of this research was to evaluate the size structure of the capture of Crassostrea virginica in the lagoons of Tamiahua and Tampamachoco, located in the north of the state of Veracruz, Mexico. Monthly samples were collected during the period from April 2011 to March 2012, by means of the fishing tackle of gafas; (Spanish word for clamp). The structure of sizes and distribution of stadiums of C. virginica, the relationship between length-weight and growth ratio of the species for each of the lagoons was determined. The oyster population of Tamiahua was dominated by two groups of individuals with sizes of 48-52 mm and of 52-56 mm. In Tampamachoco, organisms with sizes of 52-56 mm and 56-60 mm were predominant. The highest proportion of juvenile oysters in Tamiahua appeared in April and in June 2011, with 28%; adults were more abundant in February 2012, with 92%. For Tampamachoco, the highest percentage of juvenile oysters was observed in July and September 2011, with 16%, and adults in October 2011 with 97%. The relationship between weight and total length of C. virginica in Tamiahua was represented by the equation: (PT=3.76 * Lt 1.18; r= 0.59181), whereas for Tampamachoco, the equation was: (PT= 2.64 * Lt 1.26 r= 0.5792). The projection of the growth equation for the Lagoon of Tamiahua showed that at the relative age of 5 years, C. virginica could reach 95% of its growth, whereas for the population of Tampamachoco, this growth percentage could be reached at the age of 4 years.El objetivo de esta investigación fue evaluar la estructura de tallas de la captura del ostión Crassostrea virginica en las lagunas de Tamiahua y Tampamachoco, ubicadas al norte de Veracruz, México. Se recolectaron muestras mensuales durante el periodo de abril 2011 a marzo 2012, mediante el arte de pesca denominado gafas. Se determinó la estructura de tallas y distribución de estadios de C. virginica, la relación longitud-peso y la tasa de crecimiento para cada laguna. La población ostrícola de Tamiahua estuvo dominada por dos grupos de individuos con tallas de 48 a 52 mm y de 52 a 56 mm. En Tampamachoco, predominaron organismos con tallas de 52 a 56 mm y de 56 a 60 mm. La mayor proporción de juveniles en Tamiahua se presentó en abril y junio con 28%, los adultos fueron más abundantes en febrero con 92%. Para Tampamachoco el mayor porcentaje de juveniles fue observado en julio y septiembre con 16% y de adultos en octubre con 97%. La relación entre el peso y longitud total, para C. virginica en la laguna de Tamiahua, estuvo representada por la ecuación: (PT = 3.76 * Lt1.18; r=0.59181) y (PT = 2.64 * Lt1.26 r=0.5792) para la laguna de Tampamachoco. La proyección de la ecuación de crecimiento para la Laguna de Tamiahua estimó que a la edad relativa de 5 años, C. virginica podría alcanzar el 95% de su crecimiento, en tanto que en la población de Tampamachoco este mismo porcentaje de crecimiento se obtendrá a la edad relativa de 4 años

Few-layer antimonene electrical properties

Antimonene -a single layer of antimony atoms- and its few layer forms are among the latest additions to the 2D mono-elemental materials family. Numerous predictions and experimental evidence of its remarkable properties including (opto)electronic, energetic or biomedical, among others, together with its robustness under ambient conditions, have attracted the attention of the scientific community. However, experimental evidence of its electrical properties is still lacking. Here, we characterized the electronic properties of mechanically exfoliated flakes of few-layer (FL) antimonene of different thicknesses (∼ 2–40 nm) through photoemission electron microscopy, kelvin probe force microscopy and transport measurements, which allows us to estimate a sheet resistance of ∼ 1200 Ω sq−1 and a mobility of ∼ 150 cm2V−1s−1 in ambient conditions, independent of the flake thickness. Alternatively, our theoretical calculations indicate that topologically protected surface states (TPSS) should play a key role in the electronic properties of FL antimonene, which supports our experimental findings. We anticipate our work will trigger further experimental studies on TPSS in FL antimonene thanks to its simple structure and significant stability in ambient environmentsWe acknowledge financial support through the “Maríade Maeztu” Programme for Units of Excellence in R&D (CEX2018-000805-M), the Spanish MINECO through projects PCI2018-093081, FIS2016-80434-P, PID2019-109539GB-C43, PID2019- 106268GB-C31 and -C32, MAT2016-77608-C3-1-P and -3-P, MAT2013-46753-C2-2-P and MAT2017-85089-C2-1R, the EU Graphene Flagship funding (Graphene Flagship Core3 881603 and JTC2017/2D-Sb&Ge), the EU via the ERC-Synergy Program (GrantERC-2013-SYG-610256 NANOCOSMOS), the Comunidad Autónoma de Madrid through MAD2D-CM, S2018/NMT-4321 (NanomagCOST-CM) and the European StructuralFunds via FotoArt CM project (S2018/NMT-4367), and the Fundación Ramón Areces. S.P. acknowledges financial support by the VILLUM FONDEN via the Centre of Excellence for Dirac Materials (Grant No. 11744

Adaptación de la asignatura “Clínica Jurídica de Acción Social” a un modelo de Aprendizaje-servicio con docencia semipresencial u online

Memoria ID-102. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2020-2021

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

New insights into the genetic etiology of Alzheimer's disease and related dementias

Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele

VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad

Acta de congresoLa conmemoración de los cien años de la Reforma Universitaria de 1918 se presentó como una ocasión propicia para debatir el rol de la historia, la teoría y la crítica en la formación y en la práctica profesional de diseñadores, arquitectos y urbanistas. En ese marco el VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad constituyó un espacio de intercambio y reflexión cuya realización ha sido posible gracias a la colaboración entre Facultades de Arquitectura, Urbanismo y Diseño de la Universidad Nacional y la Facultad de Arquitectura de la Universidad Católica de Córdoba, contando además con la activa participación de mayoría de las Facultades, Centros e Institutos de Historia de la Arquitectura del país y la región. Orientado en su convocatoria tanto a docentes como a estudiantes de Arquitectura y Diseño Industrial de todos los niveles de la FAUD-UNC promovió el debate de ideas a partir de experiencias concretas en instancias tales como mesas temáticas de carácter interdisciplinario, que adoptaron la modalidad de presentación de ponencias, entre otras actividades. En el ámbito de VIII Encuentro, desarrollado en la sede Ciudad Universitaria de Córdoba, se desplegaron numerosas posiciones sobre la enseñanza, la investigación y la formación en historia, teoría y crítica del diseño, la arquitectura y la ciudad; sumándose el aporte realizado a través de sus respectivas conferencias de Ana Clarisa Agüero, Bibiana Cicutti, Fernando Aliata y Alberto Petrina. El conjunto de ponencias que se publican en este Repositorio de la UNC son el resultado de dos intensas jornadas de exposiciones, cuyos contenidos han posibilitado actualizar viejos dilemas y promover nuevos debates. El evento recibió el apoyo de las autoridades de la FAUD-UNC, en especial de la Secretaría de Investigación y de la Biblioteca de nuestra casa, como así también de la Facultad de Arquitectura de la UCC; va para todos ellos un especial agradecimiento

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat