16 research outputs found

    Analytical approach to relaxation dynamics of condensed Bose gases

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    The temporal evolution of a perturbation of the equilibrium distribution of a condensed Bose gas is investigated using the kinetic equation which describes collision between condensate and noncondensate atoms. The dynamics is studied in the low momentum limit where an analytical treatment is feasible. Explicit results are given for the behavior at large times in different temperature regimes.Comment: 25 pages, 3 figures. Typos corrected. Final version to appear in Annals of Physic

    Brugada syndrome masked by complete left bundle branch block: A clinical and functional study of its association with the p.1449Y>H SCN5A variant

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    SCN5A gene variants are associated with both Brugada syndrome and conduction disturbances, sometimes expressing an overlapping phenotype. Functional consequences of SCN5A variants assessed by patch‐clamp electrophysiology are particularly beneficial for correct pathogenic classification and are related to disease penetrance and severity. Here, we identify a novel SCN5A loss of function variant, p.1449Y>H, which presented with high penetrance and complete left bundle branch block, totally masking the typical findings on the electrocardiogram. We highlight the possibility of this overlap combination that makes impossible an electrocardiographic diagnosis and, through a functional analysis, associate the p.1449Y>H variant to SCN5A pathogenicity.Sociedad Española de Cardiología Ritmo 2017Consejería de Salud of the Junta de Andalucía PI‐0365‐201

    Verification of measured PV energy yield versus forecast and loss analysis

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    Yield forecasting of the commercial design tool PVsyst (v5.6) is compared to the performance measurements of multi crystalline modules in Dietikon, Zurich, during 2011. The total measured horizontal irradiance was 1146 kWh/m2 in 2011. This pyranometer measurement covers 91.5% of the total annual irradiance (determined using IDAWEB data with 100% uptime for Affoltern). The historical irradiance data averaged over decades are about 11.4% (Meteonorm) or 13.6% (PVGIS) lower than the IDAWEB data in 2011. The standard deviation between 2001 and 2011 is about 4.9% with respect to IDAWEB. The measured DC performance ratio (PRDC) is 0.937 with a measurement uncertainty of ±0.031 (k=2). Simulations with manufacturer and optimised parameters showed a deviation to the measurement between 4% and 8%. A second analysis considers shading losses for different shading angles. Calculated losses are about 2% lower than simulated losses with PVsyst using a model of partial shading for a shading angle of 20°. Interesting results could be achieved by determining the loss upon limiting the inverter output power. There is only 4.4% annual loss when the inverter output power is set to a limit of 70 % for the location Dietikon in 2011

    Energy rating based on thermal modelling of five different PV technologies

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    Minute by minute outdoor measurements of five commercial PV modules including multi c-Si, HIT, a-Si/μc-Si, CIS, CdTe over one year were used to develop a model for predicting the individual module temperatures. The simulated module temperatures over a whole year in minute interval correspond to the outdoor measured values within a RMSE of 1.5°C. Input of the model includes irradiance measurements, which are extracted from the measured short circuit current ISC, the measured wind speed and the ambient temperature. The measured energy weighted module temperature for Zurich was found to be between 33.3°C and 38.0°C for the different module types with a maximum difference of 0.8°C relative to the simulated average module temperature. Due to the high module temperature, the annual average efficiency was reduced relative to the STC values by only 2.6% (HIT) and 5.6% (CIS). Another reduction of the STC efficiency could clearly be attributed to the efficiency at low ISC values which classify low irradiance values. The value is a decrease of the annual energy output of 4.7% and an increase of 1.1%. A further loss analysis was performed to separate spectrum related losses resulting in a relative difference of 2% for the tandem compared to the multi c-Si module

    Nueva variante KCNQ1 c.604 + 1G >C asociada con síndrome de Jervell-Lange Nielsen en homocigosis y heterocigosis compuesta

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    El presente trabajo ha sido financiado por la Sociedad Española de Cardiología (Beca Ritmo 17) y la Consejería de Salud de la Junta de Andalucía (PI-0365-2017)Peer reviewe

    Brugada syndrome masked by complete left bundle branch block: A clinical and functional study of its association with the p.1449Y>H SCN5A variant

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    SCN5A gene variants are associated with both Brugada syndrome and conduction disturbances, sometimes expressing an overlapping phenotype. Functional consequences of SCN5A variants assessed by patch-clamp electrophysiology are particularly beneficial for correct pathogenic classification and are related to disease penetrance and severity. Here, we identify a novel SCN5A loss of function variant, p.1449Y>H, which presented with high penetrance and complete left bundle branch block, totally masking the typical findings on the electrocardiogram. We highlight the possibility of this overlap combination that makes impossible an electrocardiographic diagnosis and, through a functional analysis, associate the p.1449Y>H variant to SCN5A pathogenicity

    Importance of Baseline Prognostic Factors With Increasing Time Since Initiation of Highly Active Antiretroviral Therapy: Collaborative Analysis of Cohorts of HIV-1-Infected Patients

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    Background: The extent to which the prognosis for AIDS and death of patients initiating highly active antiretroviral therapy (HAART) continues to be affected by their characteristics at the time of initiation (baseline) is unclear. Methods: We analyzed data on 20,379 treatment-naive HIV-1- infected adults who started HAART in 1 of 12 cohort studies in Europe and North America (61,798 person-years of follow-up, 1844 AIDS events, and 1005 deaths). Results: Although baseline CD4 cell count became less prognostic with time, individuals with a baseline CD4 count 350 cells/μL (hazard ratio for AIDS = 2.3, 95% confidence interval [CI]: 1.0 to 2.3; mortality hazard ratio = 2.5, 95% CI: 1.2 to 5.5, 4 to 6 years after starting HAART). Rates of AIDS were persistently higher in individuals who had experienced an AIDS event before starting HAART. Individuals with presumed transmission by means of injection drug use experienced substantially higher rates of AIDS and death than other individuals throughout follow-up (AIDS hazard ratio = 1.6, 95% CI: 0.8 to 3.0; mortality hazard ratio = 3.5, 95% CI: 2.2 to 5.5, 4 to 6 years after starting HAART). Conclusions: Compared with other patient groups, injection drug users and patients with advanced immunodeficiency at baseline experience substantially increased rates of AIDS and death up to 6 years after starting HAART
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