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Mutual fund performance and management location
In this article we develop and explore the most comprehensive database of fund manager performance delineated by location. We use this database and four performance evaluation techniques to determine whether a fund manager's location relative to the location of the securities they manage are listed and traded has any impact on fund performance. The main results of our article are very positive for the US fund management industry. Any investor wishing to invest in a US equity mutual fund would be well advised to have this portfolio managed by a manager based in the United States. Compared with European managers of US equity mutual funds, US managers produce higher mean alpha and display a far greater tendency for positive performance persistence
Highly Dispersive Spin Excitations in the Chain Cuprate Li2CuO2
We present an inelastic neutron scattering investigation of Li2CuO2 detecting
the long sought quasi-1D magnetic excitations with a large dispersion along the
CuO2-chains studied up to 25 meV. The total dispersion is governed by a
surprisingly large ferromagnetic (FM) nearest-neighbor exchange integral
J1=-228 K. An anomalous quartic dispersion near the zone center and a
pronounced minimum near (0,0.11,0.5) r.l.u. (corresponding to a spiral
excitation with a pitch angle about 41 degree point to the vicinity of a 3D
FM-spiral critical point. The leading exchange couplings are obtained applying
standard linear spin-wave theory. The 2nd neighbor inter-chain interaction
suppresses a spiral state and drives the FM in-chain ordering below the Ne'el
temperature. The obtained exchange parameters are in agreement with the results
for a realistic five-band extended Hubbard Cu 3d O 2p model and L(S)DA+U
predictions.Comment: 6 pages, 4 figures, submitted to Europhys. Let
Sound Multi-Party Business Protocols for Service Networks
Service networks comprise large numbers of long-running, highly dynamic complex end-to-end service interactions reflecting asynchronous message flows that typically transcend several organizations and span several geographical locations. At the communication level, service network business protocols can be flexible ranging from conventional inter-organizational point-to-point service interactions to fully blown dynamic multi-party interactions of global reach within which each participant may contribute its activities and services. In this paper we introduce a formal framework enriched with temporal constraints to describe multiparty business protocols for service networks. We extend this framework with the notion of multi-party business protocol soundness and show how it is possible to execute a multi-party protocol consistently in a completely distributed manner while guaranteeing eventual termination
Coalescent angiogenesis—evidence for a novel concept of vascular network maturation
Angiogenesis describes the formation of new blood vessels from pre-existing vascular structures. While the most studied mode of angiogenesis is vascular sprouting, specific conditions or organs favor intussusception, i.e., the division or splitting of an existing vessel, as preferential mode of new vessel formation. In the present study, sustained (33-h) intravital microscopy of the vasculature in the chick chorioallantoic membrane (CAM) led to the hypothesis of a novel non-sprouting mode for vessel generation, which we termed "coalescent angiogenesis." In this process, preferential flow pathways evolve from isotropic capillary meshes enclosing tissue islands. These preferential flow pathways progressively enlarge by coalescence of capillaries and elimination of internal tissue pillars, in a process that is the reverse of intussusception. Concomitantly, less perfused segments regress. In this way, an initially mesh-like capillary network is remodeled into a tree structure, while conserving vascular wall components and maintaining blood flow. Coalescent angiogenesis, thus, describes the remodeling of an initial, hemodynamically inefficient mesh structure, into a hierarchical tree structure that provides efficient convective transport, allowing for the rapid expansion of the vasculature with maintained blood supply and function during development
Brain glucose utilization in systemic lupus erythematosus with neuropsychiatric symptoms: A controlled positron emission tomography study
In contrast to morphological imaging [such as magnetic resonance imaging (MRI) or computed tomography], functional imaging may be of advantage in the detection of brain abnormalities in cases of neuropsychiatric systemic lupus erythematosus (SLE). Therefore, we studied 13 patients (aged 40±14 years, 11 female, 2 male) with neuropsychiatric SLE who met four of the American Rheumatism Association criteria for the classification of SLE. Ten clinically and neurologically healthy volunteers served as controls (aged 40±12 years, 5 female, 5 male). Both groups were investigated using fluorine-18-labelled fluorodeoxyglucose brain positron emission tomography (PET) and cranial MRI. The normal controls and 11 of the 13 patients showed normal MRI scans. However, PET scan was abnormal in all 13 SLE patients. Significant group-to-group differences in the glucose metabolic index (GMI=region of interest uptake/global uptake at the level of the basal ganglia and thalamus) were found in the parieto-occipital region on both sides: the GMI of the parieto-occipital region on the right side was 0.922±0.045 in patients and 1.066±0.081 in controls (P<0.0001, Mann WhitneyU test), while on the left side it was 0.892±0.060 in patients and 1.034±0.051 in controls (P=0.0002). Parietooccipital hypometabolism is a conspicuous finding in mainly MRI-negative neuropsychiatric SLE. As the parieto-occipital region is located at the boundary of blood supply of all three major arteries, it could be the most vulnerable zone of the cerebrum and may be affected at an early stage of the cerebrovascular diseas
Promoção da Qualidade das Relações Interpessoais, da Saúde e do Bem-Estar dos Enfermeiros do HFF: o Projeto, Resultados T1, e a Fase de Intervenção
Promoção da qualidade das relações interpessoais, da saúde e do bem-estar dos enfermeiros do HFF: O projeto, resultados T1 e a fase de intervenção
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