Laccase-catalyzed decolorization of the synthetic azo-dye diamond black PV 200 and of some structurally related derivatives

The kinetics of laccase-catalyzed transformation of the azo-dye Diamond Black PV 200 (CI Mordant Black 9) and various related synthesized derivatives were analyzed for dependence on pH and substrate structure. The reaction mixture of Diamond Black PV 200 was analyzed by HPLC/MS_/MS and it was shown that upon laccase oxidation, reactive chinoid fragments of lower molecular weight were formed. These may further oligomerize as indicated by the appearance of a number of compounds with increased molecular weight. The pH optimum for the decolorization was pH 5 for Diamond Black PV 200 which did not change significantly when the substitution pattern of its basic structure was varied. Biodegradability, however, was strongly dependent on the structure of the dyes

Observational Constraints on the Dependence of Radio-Quiet Quasar X-ray Emission on Black Hole Mass and Accretion Rate

In this work we use a sample of 318 radio-quiet quasars (RQQ) to investigate the dependence of the ratio of optical/UV flux to X-ray flux, alpha_ox, and the X-ray photon index, Gamma_X, on black hole mass, UV luminosity relative to Eddington, and X-ray luminosity relative to Eddington. Our sample is drawn from the SDSS, with X-ray data from ROSAT and Chandra, and optical data mostly from the SDSS; 153 of these sources have estimates of Gamma_X from Chandra. We estimate M_BH using standard estimates derived from the Hbeta, Mg II, and C IV broad emission lines. Our sample spans a broad range in black hole mass (10^6 < M_BH / M_Sun < 10^10) and redshift (z < 4.8). We find that alpha_ox increases with increasing M_BH and L_UV / L_Edd, and decreases with increasing L_X / L_Edd. In addition, we confirm the correlation seen in previous studies between Gamma_X and M_BH and both L_UV / L_Edd and L_X / L_Edd; however, we also find evidence that the dependence of Gamma_X of these quantities is not monotonic, changing sign at M_BH ~ 3 x 10^8 M_Sun. We argue that the alpha_ox correlations imply that the fraction of bolometric luminosity emitted by the accretion disk, as compared to the corona, increases with increasing accretion rate relative to Eddington. In addition, we argue that the Gamma_X trends are caused by a dependence of X-ray spectral index on accretion rate. We discuss our results within the context of accretion models with comptonizing corona, and discuss the implications of the alpha_ox correlations for quasar feedback. To date, this is the largest study of the dependence of RQQ X-ray parameters on black hole mass and related quantities, and the first to attempt to correct for the large statistical uncertainty in the broad line mass estimates.Comment: Accepted by ApJ, 23 pages, 15 figures, emulateapj styl

The LBT Panoramic View on the Recent Star-Formation Activity in IC2574

We present deep imaging of the star-forming dwarf galaxy IC2574 in the M81 group taken with the Large Binocular Telescope in order to study in detail the recent star-formation history of this galaxy and to constrain the stellar feedback on its HI gas. We identify the star-forming areas in the galaxy by removing a smooth disk component from the optical images. We construct pixel-by-pixel maps of stellar age and stellar mass surface density in these regions by comparing their observed colors with simple stellar populations synthesized with STARBURST99. We find that an older burst occurred about 100 Myr ago within the inner 4 kpc and that a younger burst happened in the last 10 Myr mostly at galactocentric radii between 4 and 8 kpc. We analyze the stellar populations residing in the known HI holes of IC2574. Our results indicate that, even at the remarkable photometric depth of the LBT data, there is no clear one-to-one association between the observed HI holes and the most recent bursts of star formation in IC2574. The stellar populations formed during the younger burst are usually located at the periphery of the HI holes and are seen to be younger than the holes dynamical age. The kinetic energy of the holes expansion is found to be on average 10% of the total stellar energy released by the stellar winds and supernova explosions of the young stellar populations within the holes. With the help of control apertures distributed across the galaxy we estimate that the kinetic energy stored in the HI gas in the form of its local velocity dispersion is about 35% of the total stellar energy.Comment: 16 pages, 14 figures, accepted for publication in Ap

An epidemiologic study of early biologic effects of benzene in Chinese workers.

Benzene is a recognized hematotoxin and leukemogen, but its mechanisms of action in humans are still uncertain. To provide insight into these processes, we carried out a cross-sectional study of 44 healthy workers currently exposed to benzene (median 8-hr time-weighted average; 31 ppm), and unexposed controls in Shanghai, China. Here we provide an overview of the study results on peripheral blood cells levels and somatic cell mutation frequency measured by the glycophorin A (GPA) gene loss assay and report on peripheral cytokine levels. All peripheral blood cells levels (i.e., total white blood cells, absolute lymphocyte count, platelets, red blood cells, and hemoglobin) were decreased among exposed workers compared to controls, with the exception of the red blood cell mean corpuscular volume, which was higher among exposed subjects. In contrast, peripheral cytokine levels (interleukin-3, interleukin-6, erythropoietin, granulocyte colony-stimulating factor, tissue necrosis factor-alpha) in a subset of the most highly exposed workers (n = 11) were similar to values in controls (n = 11), suggesting that benzene does not affect these growth factor levels in peripheral blood. The GPA assay measures stem cell or precursor erythroid cell mutations expressed in peripheral red blood cells of MN heterozygous subjects, identifying NN variants, which result from loss of the GPA M allele and duplication of the N allele, and N phi variants, which arise from gene inactivation. The NN (but not N phi) GPA variant cell frequency was elevated in the exposed workers compared with controls (mean +/- SD, 13.9 +/- 8.4 mutants per million cells versus 7.4 +/- 5.2 per million cells, (respectively; p = 0.0002), suggesting that benzene produces gene-duplicating but not gene-inactivating mutations at the GPA locus in bone marrow cells of exposed humans. These findings, combined with ongoing analyses of benzene macromolecular adducts and chromosomal aberrations, will provide an opportunity to comprehensively evaluate a wide range of early biologic effects associated with benzene exposure in humans

Effects of manipulating hypothalamic triiodothyronine concentrations on seasonal body weight and torpor cycles in siberian hamsters

Peer reviewedPublisher PD

The first XMM-Newton spectrum of a high redshift quasar - PKS 0537-286

We present XMM-Newton observations of the high redshift z=3.104, radio-loud quasar PKS 0537-286. The EPIC CCD cameras provide the highest signal-to-noise spectrum of a high-z quasar to date. The EPIC observations show that PKS 0537-286 is extremely X-ray luminous (Lx=2x10^47 erg/s), with an unusually hard X-ray spectrum (Gamma=1.27+/-0.02). The flat power-law emission extends over the whole observed energy range; there is no evidence of intrinsic absorption, which has been claimed in PKS 0537-286 and other high z quasars. However, there is evidence for weak Compton reflection. A redshifted iron K line, observed at 1.5 keV - corresponding to 6.15 keV in the quasar rest frame - is detected at 95% confidence. If confirmed, this is the most distant iron K line known. The line equivalent width is small (33eV), consistent with the `X-ray Baldwin effect' observed in other luminous quasars. The reflected continuum is also weak (R=0.25). We find the overall spectral energy distribution of PKS 0537-286 is dominated by the X-ray emission, which, together with the flat power-law and weak reflection features, suggests that the X-radiation from PKS 0537-286 is dominated by inverse Compton emission associated with a face-on relativistic jet.Comment: 6 pages, accepted for publication in Astronomy and Astrophysics Letter

Segue 2: A Prototype of the Population of Satellites of Satellites

We announce the discovery of a new Milky Way satellite Segue 2 found in the data of the Sloan Extension for Galactic Understanding and Exploration (SEGUE). We followed this up with deeper imaging and spectroscopy on the Multiple Mirror Telescope. From this, we derive a luminosity of M_v = -2.5, a half-light radius of 34 pc and a systemic velocity of -40$ km/s. Our MMT data also provides evidence for a stream around Segue 2 at a similar heliocentric velocity, and the SEGUE data show that it is also present in neighboring fields. We resolve the velocity dispersion of Segue 2 as 3.4 km/s and the possible stream as about 7 km/s. This object shows points of comparison with other recent discoveries, Segue 1, Boo II and Coma. We speculate that all four objects may be representatives of a population of satellites of satellites -- survivors of accretion events that destroyed their larger but less dense parents. They are likely to have formed at redshifts z > 10 and are good candidates for fossils of the reionization epoch.Comment: MNRAS, Submitte

Evolution of the X-ray Emission of Radio-Quiet Quasars

We report new Chandra observations of seven optically faint, z \sim 4 radio-quiet quasars. We have combined these new observations with previous Chandra observations of radio-quiet quasars to create a sample of 174 sources. These sources have 0.1 < z < 4.7, and 10^{44} ergs s^{-1} < nu L_{nu} (2500 \AA) < 10^{48} ergs s^{-1}. The X-ray detection fraction is 90%. We find that the X-ray loudness of radio-quiet quasars decreases with UV luminosity and increases with redshift. The model that is best supported by the data has a linear dependence of optical-to-X-ray ratio, alpha_{ox}, on cosmic time, and a quadratic dependence of alpha_{ox} on log L_{UV}, where alpha_{ox} becomes X-ray quiet more rapidly at higher log L_{UV}. We find no significant evidence for a relationship between the X-ray photon index, Gamma_X, and the UV luminosity, and we find marginally significant evidence that the X-ray continuum flattens with increasing z (2 sigma). The Gamma_X-z anti-correlation may be the result of X-ray spectral curvature, redshifting of a Compton reflection component into the observed Chandra band, and/or redshifting of a soft excess out of the observed Chandra band. Using the results for Gamma_X, we show that the alpha_{ox}-z relationship is unlikely to be a spurious result caused by redshifting of the observable X-ray spectral region. A correlation between alpha_{ox} and z implies evolution of the accretion process. We present a qualitative comparison of these new results with models for accretion disk emission.Comment: Accepted by ApJ, 48 pages, 10 figures, 5 table

A high velocity ionised outflow and XUV photosphere in the narrow emission line quasar PG1211+143

We report on the analysis of a ~60 ksec XMM observation of the bright, narrow emission line quasar PG 1211+143. Absorption lines are seen in both EPIC and RGS spectra corresponding to H- and He-like ions of Fe, S, Mg, Ne, O, N and C. The observed line energies indicate an ionised outflow velocity of ~24000 km s^-1. The highest energy lines require a column density of N_H ~ 5 x 10^23 cm^-2, at an ionisation parameter of log(xi) ~ 3.4. If the origin of this high velocity outflow lies in matter being driven from the inner disc, then the flow is likely to be optically thick within a radius ~130 Schwarzschild radii, providing a natural explanation for the Big Blue Bump (and strong soft X-ray) emission in PG 1211+143.Comment: Accepted by MNRAS; Table 1 correcte

The discovery of Segue 2: a prototype of the population of satellites of satellites

We announce the discovery of a new Milky Way satellite Segue 2 found in the data of the Sloan Extension for Galactic Understanding and Exploration (SEGUE). We followed this up with deeper imaging and spectroscopy on the Multiple Mirror Telescope (MMT). From this, we derive a luminosity of Mv=−2.5, a half-light radius of 34 pc and a systemic velocity of ∼−40 km s−1. Our data also provide evidence for a stream around Segue 2 at a similar heliocentric velocity, and the SEGUE data show that it is also present in neighbouring fields. We resolve the velocity dispersion of Segue 2 as 3.4 km s−1 and the possible stream as ∼7 km s−1. This object shows points of comparison with other recent discoveries, Segue 1, Boo II and Coma. We speculate that all four objects may be representatives of a population of satellites of satellites - survivors of accretion events that destroyed their larger but less dense parents. They are likely to have formed at redshifts z > 10 and are good candidates for fossils of the reionization epoc