EL BEISBALÓN”, JUEGO PREDEPORTIVO PARA PROPICIAR LA MOTIVACIÓN DESDE LA CLASE DE EDUCACIÓN FÍSICA

Physical Education is an area with great potential through which students express the level of motor, cognitive, emotional, emotional and creative development achieved; It plays an important role in learning motor actions or behaviors. This research work is aimed at promoting motivation and participation from the Physical Education classes, encouraging sports initiation with a playful approach at these ages, for which a didactic game is designed that contains educational, extradocent actions. The type of study used was experimental-descriptive. The methods used were among theorists, the analytic-synthetic; within the empirical survey and documentary analysis and as a statistical-mathematical, descriptive statistics. The results reveal the need for trained professors to direct the practice of physical exercises in the university. The lack of knowledge on the part of the specialists is verified, in the dosage and planning of the game, during the Physical Education class.La Educación Física constituye un área con grandes potencialidades a través de la cual los estudiantes expresan el nivel de desarrollo motor, cognitivo, afectivo, emocional y creativo alcanzado; desempeña un importante papel en el aprendizaje de acciones o conductas motrices. El presente trabajo investigativo está dirigido a  propiciar la motivación y participación desde la clases de Educación Física, fomentando en estas edades la iniciación deportiva con un enfoque lúdico, para lo cual se diseña un juego didáctico que contiene acciones de carácter educativo, extradocente. El tipo de estudio empleado fue experimental-descriptivo.  Los métodos utilizados fueron entre los teóricos, el analítico-sintético; dentro de los empíricos la encuesta y el análisis documental y como estadístico-matemático, la estadística descriptiva. Los resultados revelan la necesidad de que profesores capacitados dirijan la práctica de ejercicios físicos en la universidad. Se comprueba el desconocimiento por parte de los especialistas, en la dosificación y planificación del juego, durante la clase de Educación Física. &nbsp

Games to motivate teaching athletics at early ages from Physical Education class

The present research, has its starting point in the existent problem for the development of Athletics in early ages, difficulty that coexists with the spreading and practice of this sport in the lessons of Physical Education in schools. For this research there has been taken a sample of students of 5th and 6th grades, between the 10 and 12 years old, from two primary schools, centering their attention to the Process of teaching-learning of athletics like object of the research. This work has been focused as objective to implement a group of alternative games to motivate the teaching of athletics from the earliest ages, through the lessons of Physical Education, contributing to the formation of the basic skills so that the student can go assimilating the different techniques in a leisure time. Different research methods were used; so much of the theoretical level, as of the empiric one, such as: analysis-synthesis, inductive-deductive, systemic-structural, analysis of documents, observation and the interview. Their application allows the professors to have a useful tool that can be used for its preparation, as well as the possibilities of generalization of the same one in other sports to motivate the lessons

Efecto del tratamiento fisioterápico en la activación autónoma y la percepción del dolor en pacientes varones con lumbalgia subaguda inespecífica

Introduction: Physiotherapy treatment is a common intervention for low back pain (LBP) patients. These interventions have been related to physiological effects in the central nervous system. Thus, the aim of this study was to analyze the effect of physiotherapy treatment in patients with LBP in the autonomic nervous system activation and subjective pain perception of patients. Methods: A total of 30 male subjects diagnosed with non-specific subacute LBP received a 50 min session consisting of (a) a manual therapy based on joint mobilization and soft tissues techniques in the lumbo-pelvic area, (b) a stretching program, and (c) motor control exercises of the core muscles. The autonomic modification of participants was assessed prior to and after the physiotherapy treatment. Results: Heart rate variability (HRV) analysis reported a significant increase in average RR (p = 0.001), RMSSD (p = 0.008), LRMSSD (p = 0.001), SDNN (p = 0.005), and PNN50 (p = 0.024) after the session. Frequency-domain measures showed a significant increase in LF (p = 0.030) and HF (p = 0.014), and a decrease in LF/HF ratio (p = 0.046). A significant decrease was found in minimum HR values (p = 0.001) and average HR (p = 0.001). Moreover, maximal HR decreased its value from 116.7 ± 26.1 to 113.7 ± 40.8 after intervention. In addition, subjective pain perception (VAS scores) was significantly lower (p = 0.001) in the post-session assessment. Conclusions: Physiotherapy treatment produced an increase in parasympathetic nervous system activation and a decrease in subjective pain perception in non-specific subacute LBP patients.Introducción: El tratamiento de fisioterapia es una intervención común para el dolor lumbar (LBP) pacientes. Estas intervenciones se han relacionado con efectos fisiológicos en el sistema nervioso central. Así, el objetivo de este estudio fue analizar el efecto del tratamiento de fisioterapia en pacientes con dolor lumbar en la activación del sistema nervioso autónomo y la percepción subjetiva del dolor de los pacientes. Métodos: Un total de 30 sujetos masculinos diagnosticados con dolor lumbar subagudo inespecífico recibieron una sesión de 50 minutos consistente en (a) una terapia manual basada en técnicas de movilización articular y tejidos blandos en el área lumbo-pélvica, (b) un programa de estiramiento y (c) ejercicios de control motor de los músculos centrales. La La modificación autonómica de los participantes se evaluó antes y después del tratamiento de fisioterapia. Resultados: el análisis de variabilidad de la frecuencia cardíaca (VFC) informó un aumento significativo en el RR promedio (p = 0,001), RMSSD (p = 0,008), LRMSSD (p = 0,001), SDNN (p = 0,005) y PNN50 (p = 0,024) después de la sesión. Las medidas en el dominio de la frecuencia mostraron un aumento significativo en LF (p = 0.030) y HF (p = 0.014), y una disminución en la relación LF / HF (p = 0.046). Se encontró una disminución significativa en la FC mínima valores (p = 0,001) y FC media (p = 0,001). Además, la FC máxima disminuyó su valor de 116,7 ± 26,1 a 113,7 ± 40,8 después de la intervención. Además, la percepción subjetiva del dolor (puntuaciones EVA) fue significativamente menor (p = 0,001) en la evaluación posterior a la sesión. Conclusiones: fisioterapia El tratamiento produjo un aumento en la activación del sistema nervioso parasimpático y una disminución en percepción subjetiva del dolor en pacientes con dolor lumbar subagudo inespecífico

Optimizing Field Body Fat Percentage Assessment in Professional Soccer Players

Body composition is a determinant of performance in soccer. To estimate the body fat percentage (%BF), dual energy X-ray absorptiometry (DXA) is effective though this method is expensive and not readily accessible. This study examines the validity of widely used field methods based on anthropometric data and bioelectrical impedance analysis (BIA). Participants were 21 male Spanish First Division soccer players aged between 22 and 35 years. In each participant, body fat mass was determined by BIA and using 18 anthropometric equations including skinfold (SKF) measurements. DXA was used as reference. Correlation with DXA measurements was excellent for all equations and separate SKF measurements yet only moderate for BIA. However, only the equation recently developed for use in soccer players based on iliac crest and triceps SKFs showed no significant or standardized differences with DXA-derived %BF and these measurements also had the lowest bias. Our findings suggest that when DXA is not available, the best field method for %BF assessment in footballers is the equation based on iliac crest and triceps SKF. As another good option, we propose the sum of triceps, subscapular, supraspinal, and abdominal SKFs, as this combination also showed good correlation with DXA

Preparation and characterization of a tumor-targeting dual-image system based on iron oxide nanoparticles functionalized with folic acid and rhodamine

Cancer is one of the diseases with most deaths worldwide, around 8.2 million annually. For this reason, several treatments and diagnostic tools have been investigated and developed over the past decades. Among them, a dual-image system has been developed to achieve and enhance the detection of cancer, which has not been done with systems currently available. The present study describes the preparation of a dual-image targeting system composed of magnetic iron oxide nanoparticles functionalized with folic acid and rhodamine; nanoparticles synthesis was achieved by a coprecipitation method; the functionalization was carried out by a carbodiimide with folic acid and/or the rhodamine isothiocyanate; conjugates were characterized by spectrometric techniques; toxicity was measured by cell proliferation assay on HeLa cells using progressive concentrations of functionalized nanoparticles. Cellular uptake assay was carried out by competitive assay on HeLa cells. Iron oxide magnetite nanoparticles, modified with folic acid and rhodamine, were successfully synthetized with a particle size lower than 20nm (TEM), EDS, HRTEM, and XDR showed highly crystalline Fe3O4 nanoparticles. Folic acid and rhodamine were conjugated with high efficiency. A significant selectivity and uptake, facilitated by surface modification of iron oxide nanoparticles with folic acid, were demonstrated.The multifunctional system showed suitable physicochemical and biological properties for cell targeting through folate receptors.This study was supported by the International Atomic Energy Agency (CRP-F22064, Contract no. 18358) and the Universidad Autónoma del Estado de México, through Project no. 3543/2013CHT

Comercio exterior del Perú en el contexto de pre - pandemia y pandemia

Objetivo: Analizar la evolución del comercio exterior del Perú en el contexto de Pre-Pandemia y Pandemia. Métodos: El enfoque de investigación es cuantitativo de tipo descriptivo, longitudinal y documental con información del Comercio Exterior del Perú desde enero 2019 a noviembre de 2021 del Banco Central de Reserva del Perú (BCRP) Resultados: En cuanto a las exportaciones e importaciones de mercancías se encontró una disrupción o cambios significativos de los flujos de exportación e importación de mercancías reflejadas en un coeficiente de asimetría negativa de las variables de estudio. Conclusiones: La significativa disrupción o cambio de los flujos de comercio exterior del Perú se explica por las medidas restrictivas implementadas a escala global, cierre de las fronteras y paralización de sectores económicos con consecuencias en el PBI de los socios comerciales reflejadas en una recesión  sincronizada a nivel mundial principal factor explicativo del comportamiento de las exportaciones respecto a las importaciones las medidas de confinamiento determinó la contracción de la demanda interna y el PBI doméstico

Impact of quality of life related to foot problems : a case-control study

[Abstract] Foot problems are highly prevalent conditions, being a frequent reason for medical and podiatric consultation. The aim of this study was to compare the differences of quality of life (QoL) related to foot health in people with and without the presence of foot problems. A case-control study was carried out in an outpatient centre, where a clinician recorded data related to sociodemographic and clinical characteristics. In addition, self-reported data on foot health-related quality of life were recorded using the Spanish version of the Foot Health Status Questionnaire. The sample consisted of 498 participants (249 cases and 249 controls), with a median age of 30 years and an interquartile range of 23 years. The differences between the groups were statistically significant for gender, age, footwear, general health, foot health, and physical activity. Cases showed lower scores for the domain of footwear, physical activity and vitality compared to controls. Foot pathologies have a negative impact on quality of life related to foot health, and the domains of footwear, general health and physical activity seem to be the factors that are associated with the presence of alterations and foot deformities

Potential use of space-based lightning detection in electric power systems

Information about lightning activity and its parameters is necessary to design and evaluate the lightning protection of an electrical power system. This information can be obtained from ground-based lightning detection networks that provide information on cloud-to-ground lightning strikes with a location accuracy of few hundred meters. Recently, the first satellite-based lightning optical detectors are operating continuously from geostationary orbits. These imagers observe the luminosity escaping from clouds to detect and locate total lightning activity with a spatial accuracy of several kilometers. This allows delineating the initiation and propagation (sometimes over tens to hundreds of kilometers before striking the ground) not observable by the ground-based networks. In this paper, we explore the use of this new technology for lightning protection in power systems. We focus on tall objects such as wind turbines and overhead transmission lines. We show how the optical detections allow identifying lightning flashes that likely produce continuing currents. This provides additional information for the identification of dangerous events and also can be used to estimate the number of upward-flashes from tall objects triggered by a nearby flash. The analysis of a transmission line shows the concentration of faults in the areas of high total lightning flash density. We found regional variations of the optical energy of the flashes along the line.This work was supported by research grants ESP2017-86263-C4-2-R funded by MCIN/AEI/ 10.13039/501100011033 and by “ERDF A way of making Europe”, by the “European Union”; and Grants PID2019- 109269RB-C42 and ENE2017-91636-EXP funded by MCIN/AEI/ 10.13039/501100011033. S. Goodman was in part supported by NASA Grant 80NSSC18K1689. M. M. F. Saba was in part supported by research grants 2012/15375–7 and 2013/05784–0, from Sao ˜ Paulo Research Foundation (FAPESP). S. Visacro was supported by a research grant (307381/2019–6) of the Brazilian National Council of Technological and Scientific Development (CNPq). The GLM data are available from the NOAA National Centers for Environmental Information (NCEI) and Cloud Service Providers (e.g., Amazon Web Services, AWS). The LIS data are available from the NASA GHRC Distributed Active Archive Center (DAAC) (https:// https://ghrc.nsstc.nasa.gov/home/access-data. The power system information for the 500 kV transmission line is provided by ISA-INTERCOLOMBIA and is supported by L. Porras.Peer ReviewedPostprint (author's final draft

Thymidylate synthase gene variants as predictors of clinical response and toxicity to fluoropyrimidine-based chemotherapy for colorectal cancer

Abstract Background: Fluoropyrimidines form the chemotherapy backbone of advanced and metastatic colorectal cancer (CRC). These drugs are frequently associated with toxicity events that result in dose adjustments and even suspension of the treatment. The thymidylate synthase (TYMS) gene is a potential marker of response and toxicity to fluoropyirimidines as this enzyme is the molecular target of these drugs. Our aim was to assess the association between variants of TYMS with response and toxicity to fluoropyrimidines in patients with CRC in independent retrospective and prospective studies. Methods: Variants namely rs45445694, rs183205964, rs2853542 and rs151264360 of TYMS were genotyped in 105 CRC patients and were evaluated to define their association with clinical response and toxicity to fluoropyrimidines. Additionally, the relationship between genotypes and tumor gene expression was analyzed by quantitative polymerase chain reaction. Results: The 2R/2R (rs45445694) was associated with clinical response (p = 0.05, odds ratio (OR) = 3.45) and severe toxicity (p = 0.0014, OR = 5.21, from pooled data). Expression analysis in tumor tissues suggested a correlation between the 2R/2R genotype and low TYMS expression. Conclusions: The allele 2R (rs45445694) predicts severe toxicity and objective response in advanced CRC patients. In addition, the alleles G(rs2853542) and 6bp-(rs151264360) are independent predictors of response failure to chemotherapy. This is the first study made on a Latin American population that points out TYMS gene variants have predictive values for response and toxicity in patients with CRC treated with fluoropyrimidine-based chemotherapy