Draft genome sequence of Pseudomonas stutzeri strain B1SMN1, a nitrogen-fixing and naphthalene-degrading strain isolated from wastewater

Peer Reviewe

Otolith microchemistry reveals contrasting intra-stock structuring in two demersal species off the Iberian Peninsula

Trabajo presentado en el 7th International Otolith Symposium, celebrado en Viña del Mar (Chile), entre el 9 y el 13 de octubre de 2023.Peer reviewe

Nivelación De Competencias Básicas Y Acompañamiento Integral Para Estudiantes De Primer Año Destacados En Contexto De La Unab

En Chile, en el año 2016 ingresaron 1.161.222 estudiantes a la educación superior. De acuerdo a cifras obtenidas desde el Ministerio de Educación, el 32,5% de quienes ingresan y provienen de colegios municipales, desertan en primer año, en tanto se estima que el 50% no egresa del programa en el cual inició su proceso. En este contexto, la intervención propuesta desde la Dirección General de Docencia de la Vicerrectoría Académica de la UNAB, a través de la implementación de la Beca de Nivelación Académica (BNA) financiada por el Ministerio de Educación del Gobierno de Chile, busca abordar el fenómeno desde una mirada multidimensional, en tanto existen diversos factores que de manera independiente como interrelacionadamente impactan a la hora de lograr el éxito académico de los estudiantes. En el diseño e implementación de este programa, se ha considerado un abordaje sistémico, en el marco de una política orientada a la retención y para ello se han definido 4 aspectos críticos que de manera articulada e integrada buscar impactar en este objetivo: Diagnóstico y caracterización de los estudiantes, tutorías académicas, talleres de habilidades y aprendizaje y seguimiento y acompañamiento integral de los estudiantes. Durante la implementación de las distintas acciones, los estudiantes beneficiarios han realizado una importante valoración positiva del proceso, manifestando su satisfacción con las estrategias ofrecidas, reconociendo el impacto que estas tendrán en su proceso académico. El diagnóstico, ha permitido caracterizar a los estudiantes y definir estrategias focalizadas, en tanto las tutorías académicas, han ido generando un avance progresivo en el rendimiento académico de los estudiantes, aumentando la cobertura y el nivel de adhesión en relación al obtenido el año 2015. El nivel de satisfacción de los estudiantes respecto a los talleres de habilidades y aprendizaje refleja que efectivamente estos contribuyen a su proceso formativo aportándoles herramientas útiles para la mejora en su desempeño. Por último, el acompañamiento integral, intencionado en la disminución de brechas y establecimiento de vínculos, ha permitido que los estudiantes cuenten con nuevos referentes dentro de la universidad facilitando su integración y permanencia. Esta estrategia coordinada por la Vicerrectoría Académica nos permite generar una plataforma única y articulada de acompañamiento a estudiantes destacados en contexto, contribuyendo a la retención, aprobación y rendimiento de los estudiantes, abordando las competencias genéricas que los ayudarán para una inclusión efectiva en la vida universitaria y asegurar su éxito académico

Accurate and fast identification of Campylobacter fetus in bulls by real-time PCR targeting a 16S rRNA gene sequence

Campylobacter fetus is an important animal pathogen that causes infectious infertility, embryonic mortality and abortions in cattle and sheep flocks. There are two recognized subspecies related with reproductive disorders in livestock: Campylobacter fetus subsp. fetus (Cff) and Campylobacter fetus subsp. venerealis (Cfv). Rapid and reliable detection of this pathogenic species in bulls is of upmost importance for disease control in dairy and beef herds as they are asymptomatic carriers. The aim of the present work was to assess the performance a real-time PCR (qPCR) method for the diagnosis of Campylobacter fetus in samples from bulls, comparing it with culture and isolation methods. 520 preputial samples were both cultured in Skirrow's medium and analyzed by qPCR. The estimated sensitivity of qPCR was 90.9% (95% CI, 69.4%–100%), and the specificity was 99.4% (95% CI, 98.6% - 100%). The proportion of C. fetus positive individuals was 2.1% by isolation and 2.5% by qPCR. Isolates were identified by biochemical tests as Cfv (n = 9) and Cff (n = 2). Our findings support the use of qPCR for fast and accurate detection of C. fetus directly from field samples of preputial smegma of bulls. The qPCR method showed to be suitable for massive screenings because it can be performed in pooled samples without losing accuracy and sensitivity.ANII: FSSA_X_2014_1_10525

Causas que afectan la adopción de tecnología en productores de yerba mate en la provincia de Misiones: enfoque cualitativo

La presente investigación brinda un diagnóstico de las razones que subyacen a la adopción de tecnología por parte de los pequeños y medianos productores familiares de yerba mate en la provincia de Misiones. El trabajo va más allá de la mirada técnica, dado que se construyó a partir de la visión del contexto de los productores, valorando sus palabras y estrategias de producción. En virtud de ello, se provee información valiosa para propiciar una construcción participativa e interinstitucional de propuestas de acción acorde a la problemática encontrada en la región.Instituto de Economía y SociologíaFil: Mayol, Ramon Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cerro Azul; ArgentinaFil: Giancola, Silvana Inés. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Economía y Sociología; ArgentinaFil: Lavecini, Maria Valeria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cerro Azul; ArgentinaFil: Aiassa, Jorge Federico. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cerro Azul; ArgentinaFil: Di Giano, Silvina. Investigadora independiente; ArgentinaFil: Salvador, María Laura. Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Da Riva, Mariano. Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Acuña, Domingo Oscar. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Cerro Azul; ArgentinaFil: Rabaglio, Marcelo Darío. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Economía y Sociología; Argentin

Impact of COVID-19 Pandemic on TAVR Activity: A Worldwide Registry

Background: The COVID-19 pandemic had a considerable impact on the provision of structural heart intervention worldwide. Our objectives were: 1) to assess the impact of the COVID-19 pandemic on transcatheter aortic valve replacement (TAVR) activity globally; and 2) to determine the differences in the impact according to geographic region and the demographic, development, and economic status of diverse international health care systems. Methods: We developed a multinational registry of global TAVR activity and invited individual TAVR sites to submit TAVR implant data before and during the COVID-19 pandemic. Specifically, the number of TAVR procedures performed monthly from January 2019 to December 2021 was collected. The adaptive measures to maintain TAVR activity by each site were recorded, as was a variety of indices relating to type of health care system and national economic indices. The primary subject of interest was the impact on TAVR activity during each of the pandemic waves (2020 and 2021) compared with the same period pre–COVID-19 (2019). Results: Data were received from 130 centers from 61 countries, with 14 subcontinents and 5 continents participating in the study. Overall, TAVR activity increased by 16.7% (2,337 procedures) between 2018 and 2019 (ie, before the pandemic), but between 2019 and 2020 (ie, first year of the pandemic), there was no significant growth (–0.1%; –10 procedures). In contrast, activity again increased by 18.9% (3,085 procedures) between 2020 and 2021 (ie, second year of the pandemic). During the first pandemic wave, there was a reduction of 18.9% (945 procedures) in TAVR activity among participating sites, while during the second and third waves, there was an increase of 6.7% (489 procedures) and 15.9% (1,042 procedures), respectively. Further analysis and results of this study are ongoing and will be available at the time of the congress. Conclusion: The COVID-19 pandemic initially led to a reduction in the number of patients undergoing TAVR worldwide, although health care systems subsequently adapted, and the number of TAVR recipients continued to grow in subsequent COVID-19 pandemic waves. Categories: STRUCTURAL: Valvular Disease: Aorti

Reassessing global change research priorities in mediterranean terrestrial ecosystems : how far have we come and where do we go from here?

Aim: Mediterranean terrestrial ecosystems serve as reference laboratories for the investigation of global change because of their transitional climate, the high spatiotemporal variability of their environmental conditions, a rich and unique biodiversity and a wide range of socio-economic conditions. As scientific development and environmental pressures increase, it is increasingly necessary to evaluate recent progress and to challenge research priorities in the face of global change. - Location: Mediterranean terrestrial ecosystems. - Methods: This article revisits the research priorities proposed in a 1998 assessment. - Results: A new set of research priorities is proposed: (1) to establish the role of the landscape mosaic on fire-spread; (2) to further research the combined effect of different drivers on pest expansion; (3) to address the interaction between drivers of global change and recent forest management practices; (4) to obtain more realistic information on the impacts of global change and ecosystem services; (5) to assess forest mortality events associated with climatic extremes; (6) to focus global change research on identifying and managing vulnerable areas; (7) to use the functional traits concept to study resilience after disturbance; (8) to study the relationship between genotypic and phenotypic diversity as a source of forest resilience; (9) to understand the balance between C storage and water resources; (10) to analyse the interplay between landscape-scale processes and biodiversity conservation; (11) to refine models by including interactions between drivers and socio-economic contexts; (12) to understand forest-atmosphere feedbacks; (13) to represent key mechanisms linking plant hydraulics with landscape hydrology. - Main conclusions:(1) The interactive nature of different global change drivers remains poorly understood. (2) There is a critical need for the rapid development of regional- and global-scale models that are more tightly connected with large-scale experiments, data networks and management practice. (3) More attention should be directed to drought-related forest decline and the current relevance of historical land use

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049