Shop in the Name of Love: A Qualitative Analysis of Fashion Mobile Design Features

This study utilized semi structured interviews to study mobile design features, specifically (a) to explore the features that drive consumer purchase and decision-making and (b) to identify which features were most prevalent in current fashion mobile apps. Seven women, between the ages of 18-22, enrolled in a southeastern university in the U.S. were purposively chosen as each had experience with shopping on mobile devices, expressed a heightened interest in fashion, belonged in the millennial generation, and displayed evidence of their smartphones being an essential part of their daily lives. Data collection was framed by Magrath and McCormick (2013) mobile design features (a) multimedia product viewing (b) product promotion and (c) consumer led interactions. Unique themes were generated and interpreted. Findings showed participants placed value on mobile design features, and used a variety of them to aid in the shopping decision process

SARS-CoV-2 variants evolve convergent strategies to remodel the host response

SARS-CoV-2 variants of concern (VOCs) emerged during the COVID-19 pandemic. Here, we used unbiased systems approaches to study the host-selective forces driving VOC evolution. We discovered that VOCs evolved convergent strategies to remodel the host by modulating viral RNA and protein levels, altering viral and host protein phosphorylation, and rewiring virus-host protein-protein interactions. Integrative computational analyses revealed that although Alpha, Beta, Gamma, and Delta ultimately converged to suppress interferon-stimulated genes (ISGs), Omicron BA.1 did not. ISG suppression correlated with the expression of viral innate immune antagonist proteins, including Orf6, N, and Orf9b, which we mapped to specific mutations. Later Omicron subvariants BA.4 and BA.5 more potently suppressed innate immunity than early subvariant BA.1, which correlated with Orf6 levels, although muted in BA.4 by a mutation that disrupts the Orf6-nuclear pore interaction. Our findings suggest that SARS-CoV-2 convergent evolution overcame human adaptive and innate immune barriers, laying the groundwork to tackle future pandemics

Investigating U.S. consumers' mobile pay through UTAUT2 and generational cohort theory: An analysis of mobile pay in pandemic times

This study investigates the differences in usage intentions and actual use behavior for m-pay pre-covid (2019) and during the Covid pandemic (2021). Furthermore, it examines the generational differences in m-pay behavior during the COVID-19 pandemic. The study extended the theoretical model of UTAUT2 with risk and generational cohorts (baby boomers, gen x, and millennials). Data was collected from 2,324 U.S. participants, and the proposed model was analyzed using structural equation modeling. The results show a significant difference in m-pay behavior pre-covid versus the Covid pandemic. Additionally, the cohorts' behavioral intention and use behavior toward m-pay differed, with baby boomers and millennials sharing similar behavior compared to generation X. This study highlights the pandemic's impact on shifting m-payment behaviors and the need to target m-payments payment behavior by generation

Drowning Awareness

Drowning is respiratory impairment resulting from fluid engulfing the airway halting ones breathing. There are two common forms of drowning known as dry drowning and near drowning. Dry drowning involves water being found within ones lungs without being under water. This form of drowning occurs twenty-four hours after swimming. Near drowning is the process of almost dying due to being submerged under water. Incidences of drowning continue to rise within the healthcare field especially amongst children. The American National Red Cross provides a guideline to help limit the amount of risks for drowning. Many times when children have been involved in drowning is due to lack of knowledge about proper ways to swim. Also, encompassing a lack of supervision. Nurses play a vital role in providing the utmost care for children who have been involved in a drowning incident. Providing proper education about swimming and ways to minimize the risk for drowning can reduce the amount of drowning occurrences. Overall, drowning continues to be on the rise and needs to be properly addressed by health care professionals to reduce the amount of fatal and non-fatal drowning events

SARS-CoV-2 variants evolve convergent strategies to remodel the host response

SARS-CoV-2 variants of concern (VOCs) emerged during the COVID-19 pandemic. Here, we used unbiased systems approaches to study the host-selective forces driving VOC evolution. We discovered that VOCs evolved convergent strategies to remodel the host by modulating viral RNA and protein levels, altering viral and host protein phosphorylation, and rewiring virus-host protein-protein interactions. Integrative computational analyses revealed that although Alpha, Beta, Gamma, and Delta ultimately converged to suppress interferon-stimulated genes (ISGs), Omicron BA.1 did not. ISG suppression correlated with the expression of viral innate immune antagonist proteins, including Orf6, N, and Orf9b, which we mapped to specific mutations. Later Omicron subvariants BA.4 and BA.5 more potently suppressed innate immunity than early subvariant BA.1, which correlated with Orf6 levels, although muted in BA.4 by a mutation that disrupts the Orf6-nuclear pore interaction. Our findings suggest that SARS-CoV-2 convergent evolution overcame human adaptive and innate immune barriers, laying the groundwork to tackle future pandemics

The SuperCam Instrument Suite on the NASA Mars 2020 Rover: Body Unit and Combined System Tests

TheSuperCaminstrumentsuiteprovidestheMars2020rover,Perseverance,with a number of versatile remote-sensing techniques that can be used at long distance as well as within the robotic-arm workspace. These include laser-induced breakdown spectroscopy (LIBS), remote time-resolved Raman and luminescence spectroscopies, and visible and in- frared (VISIR; separately referred to as VIS and IR) reflectance spectroscopy. A remote micro-imager (RMI) provides high-resolution color context imaging, and a microphone can be used as a stand-alone tool for environmental studies or to determine physical properties of rocks and soils from shock waves of laser-produced plasmas. SuperCam is built in three parts: The mast unit (MU), consisting of the laser, telescope, RMI, IR spectrometer, and associated electronics, is described in a companion paper. The on-board calibration targets are described in another companion paper. Here we describe SuperCam’s body unit (BU) and testing of the integrated instrument.The BU, mounted inside the rover body, receives light from the MU via a 5.8 m opti- cal fiber. The light is split into three wavelength bands by a demultiplexer, and is routed via fiber bundles to three optical spectrometers, two of which (UV and violet; 245–340 and 385–465 nm) are crossed Czerny-Turner reflection spectrometers, nearly identical to their counterparts on ChemCam. The third is a high-efficiency transmission spectrometer contain- ing an optical intensifier capable of gating exposures to 100 ns or longer, with variable delay times relative to the laser pulse. This spectrometer covers 535–853 nm (105–7070 cm−1 Ra- man shift relative to the 532 nm green laser beam) with 12 cm−1 full-width at half-maximum peak resolution in the Raman fingerprint region. The BU electronics boards interface with the rover and control the instrument, returning data to the rover. Thermal systems maintain a warm temperature during cruise to Mars to avoid contamination on the optics, and cool the detectors during operations on Mars.Results obtained with the integrated instrument demonstrate its capabilities for LIBS, for which a library of 332 standards was developed. Examples of Raman and VISIR spec- troscopy are shown, demonstrating clear mineral identification with both techniques. Lumi- nescence spectra demonstrate the utility of having both spectral and temporal dimensions. Finally, RMI and microphone tests on the rover demonstrate the capabilities of these sub- systems as well

Global urban environmental change drives adaptation in white clover

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale

\u3ci\u3eDrosophila\u3c/i\u3e Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution

The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. We find that F elements have greater transposon density (25–50%) than euchromatic reference regions (3–11%). Among the F elements, D. grimshawi has the lowest transposon density (particularly DINE-1: 2% vs. 11–27%). F element genes have larger coding spans, more coding exons, larger introns, and lower codon bias. Comparison of the Effective Number of Codons with the Codon Adaptation Index shows that, in contrast to the other species, codon bias in D. grimshawi F element genes can be attributed primarily to selection instead of mutational biases, suggesting that density and types of transposons affect the degree of local heterochromatin formation. F element genes have lower estimated DNA melting temperatures than D element genes, potentially facilitating transcription through heterochromatin. Most F element genes (~90%) have remained on that element, but the F element has smaller syntenic blocks than genome averages (3.4–3.6 vs. 8.4–8.8 genes per block), indicating greater rates of inversion despite lower rates of recombination. Overall, the F element has maintained characteristics that are distinct from other autosomes in the Drosophila lineage, illuminating the constraints imposed by a heterochromatic milieu