Action Plan Guidance and Tutorial for Students in a Situation of Social Disadvantage. Case Study

En los sistemas educativos actuales (incluido el nuestro) se da mucha importancia al desarrollo de competencias en el ámbito de lo afectivo, social y personal. Esto contrasta con modelos tradicionales basados en aspectos instructivos. En este terreno la orientación tiene un papel esencial para todo el alumnado y muy especialmente para los alumnos/as con necesidades educativas especiales (ACNEES). En esta comunicación presentamos una propuesta curricular en un entorno de desventaja social.In the current educational systems (including ours) is given much importance to the development of skills in the realm of the emotional, social and personal. This contrasts with traditional models based on instructional issues. Guidance in this area has an essential role for all students and especially for alumni / ae with special educational needs (SEN). In this communication we present a curriculum in an environment of social disadvantage

Education Proposal in Intercultural Settings

El tema en entorno al cual va a girar este trabajo es la multiculturalidad, es decir, la existencia de varias y diferentes culturas en una misma nación o en una misma realidad geográfica, diversidad que acepta y tolera el mantenimiento de la identidad cultural de todos y cada uno de los grupos minoritarios. Este fenómeno se produce en la escuela debido al movimiento inmigratorio actual. Esta primera parte será más teórica y con ella daremos lugar a una segunda que será práctica en la que se propondrá un proyecto estándar para aquellos centros en los que se visualizan varias culturas. Pretendemos que a través de él, nuestros alumnos (sean inmigrantes o no) se preparen para desenvolverse en las diferentes redes sociales en que participan, dentro de una dinámica de diálogos, contacto con otros centros y exposiciones mediante videoconferencia; nuestros alumnos tendrán la oportunidad de conocer más a fondo otras culturas.The theme around which to rotate this work is multiculturalism, ie the existence of several different cultures in one nation or in the same geographical reality that accepts and tolerates diversity maintaining the cultural identity of each and each of the minority groups. This phenomenon occurs in school due to current immigration movement. This first part is more theoretical and give her a second place to practice that will be offered a standard project for those centers that are displayed in various cultures. We intend that through it, our students (whether immigrants or not) are prepared to function in different social networks in which they participate in a dynamic dialogue, contact with other schools via video conference and exhibition, our students have the opportunity to learn more about other cultures

New Times, New Ways Of Teaching And Learning: Perception Of The EHEA And Pedagogical Discussion

It is 2010, the established deadline of the European Higher Education Area (EHEA). The Bologna Process is an unstoppable reality. But we can not admit that this change, simply by being a significant change, must be for good. We can not also disregard the potential positive pedagogical reform the Bologna Process offers to us. Then, what is the reality of the Bologna Process in Spain? What is the perception of students and teachers? Are there differences in their responses regarding the European Credit Transfer System (ECTS)? What are the pedagogical implications of these answers? This paper provides empirical evidences to these questions through the use of two questionnaires prepared ad hoc according to the pedagogical principles derived from the so-called Bologna Declaration

Effects of Nrf2 deficiency on bone microarchitecture in an experimental model of osteoporosis

Objective. Redox imbalance contributes to bone fragility. We have evaluated the in vivo role of nuclear factor erythroid derived 2-related factor-2 (Nrf2), an important regulator of cellular responses to oxidative stress, in bone metabolism using a model of postmenopausal osteoporosis. Methods. Ovariectomy was performed in both wild-type and mice deficient in Nrf2 (Nrf2-/-). Bone microarchitecture was analyzed by CT. Serum markers of bone metabolism were also measured. Reactive oxygen species production was determined using dihydrorhodamine 123. Results. Sham-operated or ovariectomized Nrf2 -/- mice exhibit a loss in trabecular bone mineral density in femur, accompanied by a reduction in cortical area in vertebrae. Nrf2 deficiency tended to increase osteoblastic markers and significantly enhanced osteoclastic markers in sham-operated animals indicating an increased bone turnover with a main effect on bone resorption. We have also shown an increased production of oxidative stress in bone marrow-derived cells from sham-operated or ovariectomized Nrf2-/- mice and a higher responsiveness of bone marrow-derived cells to osteoclastogenic stimuli in vitro. Conclusion. We have demonstrated in vivo a key role of Nrf2 in the maintenance of bone microarchitectureThis work was supported by grants SAF2010-22048, SAF2010-17822, RD12/0043/0013 (Ministerio de Economía y Competitividad, ISCIII, FEDER), and Prometeo2010-047 (Generalitat Valenciana). Lidia Ibáñez thanks Spanish Ministerio de Economía y Competitividad for a fellowship (FPI

Detección de prescripciones potencialmente inapropiadas en pacientes ancianos: estudio descriptivo en dos farmacias comunitarias

Introducción: Los ancianos son un grupo de pacientes heterogéneos a los que se les prescribe un número elevado de medicamentos. Esto conlleva a prescripciones potencialmente inapropiadas.Objetivo: Analizar la farmacoterapia del paciente anciano desde la farmacia comunitaria para detectar prescripciones potencialmente inapropiadas (Beers 2012 y STOPP) y prescripciones potencialmente omitidas (START), determinando su prevalencia.Metodología: Estudio descriptivo, observacional en el que se incluyeron pacientes mayores de 65 años de atención primaria que llevaban al menos un tratamiento crónico. Se verificó la idoneidad de la medicación según los criterios Beers 2012 y STOPP & START.Resultados: Se incluyeron 223 pacientes con una edad media de 75 años. En total se prescribieron 1.558 medicamentos, con una media de 7 medicamentos por paciente. El 67 % de los pacientes eran polimedicados. Con Beers 2012 se detectaron 246 prescripciones inapropiadas y el criterio que más se repitió fue el de benzodiazepinas de acción corta, intermedia y larga (36 %). Con STOPP se detectaron 146 prescripciones inapropiadas. El criterio más frecuente fue IBP a dosis plenas durante más de 8 semanas (14 %). Con START se detectaron 103 prescripciones potencialmente omitidas, siendo antiagregantes plaquetarios en diabetes mellitus la más frecuente (11,6 %).Conclusiones: Los criterios Beers 2012 y STOPP-START, suponen una herramienta de utilidad en la detección de los posibles problemas relacionados con los medicamentos en una farmacia comunitaria. En ningún caso suponen una prohibición en la utilización de dichos medicamentos, puesto que su prescripción dependerá de las características del paciente en concreto y del juicio clínico del médico prescriptor

Heme oxygenase-1 regulates the progression of K/BxN serum transfer arthritis

Heme oxygenase-1 (HO-1) is induced in many cell types as a defense mechanism against stress. We have investigated the possible role of endogenous HO-1 in the effector phase of arthritis using the K/BxN serum transfer model of arthritis in HO-1 heterozygous and homozygous knock-out mice. Methodology/Principal Findings. Arthritis was induced in C57/Black-6 xFVB (HO-1+/+, HO-1+/− and HO-1−/−) mice by intraperitoneal injection of 150 µl serum from arthritic K/BxN mice at days 0 and 2. Blood was collected and animals were sacrificed at day 10. Histological analysis was performed in ankle sections. The levels of inflammatory mediators were measured in serum and paw homogenates by enzyme-linked immunosorbent assay or Multiplex technology. The incidence of arthritis was higher in HO-1+/− and HO-1−/− groups compared with HO-1+/+. The inflammatory response was aggravated in HO-1+/− mice as shown by arthritic score and the migration of inflammatory cells that could be related to the enhancement of CXCL-1 production. In addition, the HO-1+/− group showed proteoglycan depletion significantly higher than HO-1+/+ mice. Serum levels of matrix metalloproteinase-3, monocyte chemotactic protein-1, plasminogen activator inhibitor-1, E-selectin and intercellular adhesion molecule-1 were increased in arthritic HO-1−/− mice, whereas vascular endothelial growth factor and some cytokines such as interferon-γ showed a reduction compared to HO-1+/+ or HO-1+/− mice. In addition, down-regulated gene expression of ferritin, glutathione S-reductase A1 and superoxide dismutase-2 was observed in the livers of arthritic HO-1+/− animals

Role of age and sex in the diagnosis of early-stage malignant melanoma: A cross-sectional study

Age and sex have been identified as predictors of outcome in malignant melanoma (MM). The aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2,430 patients with MM were recruited. Cases of in situ (Tis) and T1 MM were more frequent than T2–T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p < 0.001), with a weak correlation between Breslow thickness and patient's age (r = 0.202, p < 0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p = 0.0001). Binary logistic regression showed a significant (p < 0.001) odds ratio for age 0–29 years (1.18), and 30–59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis–T1 frequency (R2 = 0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM

Fortalezas y debilidades de la implantación de un programa de mediación en educación secundaria

ABSTRACTThis article results of the study of the implantation an educational mediation service in a Secondary School in Alicante during the academic year 2009/10. Its purpose is to value the efficiency of a collective action, which tries to make effective the educational aims of prevention, development and social intervention. To carry out this research, a qualitative methodology has been used, based on the study of the results of a questionnaire completed by twenty-six students, who have participated in this programme. The results of that tool have been processed through the qualitative programme named AQUAD 6 (Huber, 2006). This programme contributes greatly to this research because it establishes several categories to understand better the main objective of it. Crucial aspects such as participation’s reason, the conflict’s origin, generated feelings, and the offers of improvement are valued. These five aspects prove that mediation systems in school centers are a valuable tool in order to improve the living together environment, feeding a dialectical culture that steps up communication skills and supportive responsibility.RESUMENEste artículo aporta los resultados del estudio de la implantación de una estrategia de mediación educativa en un Instituto de Educación Secundaria, de Alicante, durante el curso académico 2009/10. Su propósito es valorar el grado de eficacia de una actuación colegiada orientada a hacer efectivos los principios educativos de prevención, desarrollo e intervención social. Para llevar a cabo la investigación se utilizó una metodología cualitativa, basada en el análisis de los resultados de un cuestionario administrado a veintiséis alumnos que trabajaron con esta técnica. Los datos obtenidos fueron procesados con el programa AQUAD 6 (Huber, 2006), emergiendo una serie de códigos y categorías semánticas que sustentan los aspectos fundamentales de esta investigación. Se analizaron las motivaciones de los alumnos hacia la participación, las causas que originaron los conflictos, los sentimientos experimentados durante el proceso de mediación, su evaluación y sus propuestas de mejora. El análisis demostró que los sistemas de mediación en los centros educativos son una herramienta valiosa que impulsa la convivencia y la cultura dialéctica, que intensifica la adquisición de competencias comunicativas y la responsabilidad solidaria.ABSTRACTThis article results of the study of the implantation an educational mediation service in a Secondary School in Alicante during the academic year 2009/10. Its purpose is to value the efficiency of a collective action, which tries to make effective the educational aims of prevention, development and social intervention. To carry out this research, a qualitative methodology has been used, based on the study of the results of a questionnaire completed by twenty-six students, who have participated in this programme. The results of that tool have been processed through the qualitative programme named AQUAD 6 (Huber, 2006). This programme contributes greatly to this research because it establishes several categories to understand better the main objective of it. Crucial aspects such as participation’s reason, the conflict’s origin, generated feelings, and the offers of improvement are valued. These five aspects prove that mediation systems in school centers are a valuable tool in order to improve the living together environment, feeding a dialectical culture that steps up communication skills and supportive responsibility

Torque de desinserción y propiedades fisico-químicas de implantes dentales grabados con ácidos fluorhídrico y nítrico: estudio experimental en perros Beagle

Objetivo: Estudiar la composición, características superficiales y respuesta al torque de desinserción de una superficie implantaria tratada inicialmente con ácido fluorhídrico y posterior pasivado con ácidos fluorhídrico y nítrico. Diseño del estudio: En una primera fase, se seleccionaron 12 implantes en los que se estudiaron las características fisico-químicas mediante mediciones de energía dispersa de rayos X (EDS), microscopio electrónico de barrido y análisis de XPS (espectrometría de fotoelectrones). Asimismo, se colocaron 24 implantes 'doce de 8 mm y doce de 10 mm de longitud-, en seis perros beagle, en los que tras un período de reposo, se procedió a la retirada de 12 implantes a las seis semanas y los 12 restantes a las doce semanas, mediante un calibrador de torque Gauge TonichiR modelo BGT150CN-S -con un rango de registro de fuerza de 0 a 150 Ncm. Resultados: El análisis de la composición química superficial mediante EDS sólo mostró la presencia de titanio en las superficies grabadas. En el análisis mediante XPS, al igual que sucede con las superficies de otros implantes dentales, aparecieron trazas de otros elementos presentes en la superficie, fundamentalmente de carbono. La morfología de la superficie tras el doble grabado con ácido, permitió observar la rugosidad creada por el ataque ácido, con una morfología bastante homogénea. Los valores de rugosidad obtenidos fueron superiores al micrómetro. Los valores medios encontrados para el torque de desinserción, a las seis semanas, fueron de 79,7 Ncm para los implantes de 8 mm de longitud y 115 Ncm para los implantes de 10 mm. A las doce semanas, estos valores incrementaron hasta 101,2 Ncm para los implantes de 8 mm y 139,7 Ncm para los implantes de 10 mm de longitud. Conclusiones: El grabado con ácido fluorhídrico y nítrico, posee características superficiales óptimas y comparables al de otras superficies. Los valores de torque de desinserción abren la posibilidad para su aplicación en clínica humana para procedimientos de carga precoz o inmediata.Objective: To study the composition, surface characteristics and response to removal torque of an implant surface subjected to hydrofluoric acid etching and posterior passivating with hydrofluoric and nitric acid. Study design: Twelve implants were initially selected and their physico-chemical characteristics were evaluated by means of energy-dispersive X-rays (EDS), scanning electron microscopy (SEM) and photoelectron spectroscopy (XPS). In addition, 24 implants ' 12 measuring 8 mm and 12 measuring 10 mm in length ' were implanted in 6 Beagle dogs. Twelve implants were removed after a recovery period of 6 weeks, followed by removal of the remaining 12 implants after 12 Medeweeks, using a torque calibrator (Gauge Tonichi® model BGT150CN-S) with a force registry range of 0-150 Ncm. Results: EDS analysis of the surface chemical composition only revealed the presence of titanium in the etched surfaces. In the same way as with the surfaces of other dental implants, XPS analysis revealed traces of other elements present in the surface, fundamentally carbon. Following dual acid etching, the surface showed the roughness resulting from acid action, with a morphology that proved to be quite homogeneous. The roughness values obtained exceeded 1 ìm. The mean removal torque values after 6 weeks were 79.7 Ncm for the 8 mm implants and 115 Ncm for the 10 mm implants. After 12 weeks, these values increased to 101.2 Ncm and 139.7 Ncm, respectively. Conclusions: Hydrofluoric and nitric acid etching affords optimum surface characteristics comparable to those of other surfaces. The recorded removal torque values raise the possibility of human clinical application for early or immediate loading procedures

Pensamiento científico-creativo y rendimiento académico || Scientific-creative thinking and academic achievement

The aim of this work is to study the relationship between scientific-creative thinking construct and academic performance in a sample of adolescents. In addition, the scientific-creative thinking instrument’s reliability will be tested. The sample was composed of 98 students (aged between 12-16 years old) attending to a Secondary School in Murcia Region (Spain). The used instruments were: a) the Scientific-Creative Thinking Test designed by Hu and Adey (2002), which was adapted to the Spanish culture by the High Abilities research team at Murcia University. The test is composed of 7 task based in the Scientific Creative Structure Model. It assesses the dimensions fluency, flexibility and originality; b) The General and Factorial Intelligence Test (IGF/5r; Yuste, 2002), which assess the abilities of general intelligence and logic reasoning, verbal reasoning, numerical reasoning and spatial reasoning; c) Students’ academic achievement by domains (scientific-technological, social-linguistic and artistic) was collected. The results showed positive and statistical significant correlations between the scientific-creative tasks and academic achievement of different domains.El objetivo del trabajo es estudiar la relación del constructo de pensamiento científico-creativo con el rendimiento académico en una muestra de alumnos adolescentes. Además de ello, se analizará la fiabilidad de la prueba de pensamiento científico-creativo que se va a utilizar en el presente trabajo. En el estudio participaron 98 estudiantes (12-16 años) de un instituto de Educación Secundaria de la Región de Murcia (España). Los instrumentos utilizados fueron: a) el test de Pensamiento Científico-Creativo (Hu y Adey, 2002); adaptado en nuestro país por el Equipo de Altas Habilidades de la Universidad de Murcia. El test consta de 7 tareas que se fundamentan en el Modelo Estructural de la Creatividad Científica (SCSM, Scientific Creativity Structure Model; Hu y Adey, 2002); mediante este test se valoran las dimensiones de fluidez, flexibilidad y originalidad; b) el test de Inteligencia General y Factorial (IGF/5r; Yuste, 2002), que evalúa las habilidades de Inteligencia General y Factorial, razonamiento lógico, razonamiento verbal, razonamiento numérico y razonamiento espacial; y c) el rendimiento académico de los alumnos por ámbitos (científico-tecnológico, lingüístico-social y artístico). Los resultados mostraron relaciones positivas y estadísticamente significativas entre las tareas de la prueba de creatividad científica y el rendimiento académico en los diferentes ámbitos