The Poetic Knowledge of Shizuki Tadao Traces of Dutch Poet Jacob Cats in Early Nineteenth-Century Japan

In the history of the Dutch-Japanese relations, Shizuki Tadao is recognised as an extraordinary scholar. However, his translations of European books from Dutch into Japanese only paint a partial picture of his research. In fact, he also developed valuable theories on language that allowed the Japanese to better grasp Dutch. Furthermore, he introduced European grammatical concepts and terminology in Japan. A lesser-known interest of Shizuki was poetry, evidenced by three citations from the Dutch poet Jacob Cats (1577‑1660), found in Shizuki’s works on language, by two Dutch poems attributed to him, and by an additional indirect reference to Shizuki’s knowledge on the theory of poetry. The present article aims at better understanding the figure of Shizuki as a scholar of Dutch and to add a piece to the research on the spreading of Cats’ emblems

Dutch grammar in Japanese words: reception and representation of European theory of grammar in the manuscripts of Shizuki Tadao (1760 – 1806)

The book analyzes the manuscript on the Dutch language attributed to the Japanese scholar of Dutch Shizuki Tadao (1760 – 1806). It is often argued that the Japanese scholars’ knowledge of Dutch was not particularly advanced, as they were mostly limited by their broken understanding of the contents of Dutch grammatical handbooks and dictionaries. The present book questions and investigates this claim with the goal of understanding the actual role played by Dutch sources in the learning of Dutch grammar.Shizuki can be considered as the first Japanese who studied the European theory of grammar. His representation of it is highly relevant within the history of linguistic thought. In the analysis of Shizuki’s manuscripts, this book concentrates on the representation of the categories of the parts of speech and of morphosyntactic phenomena related to verbs. While describing Dutch grammar, Shizuki often mentions other Japanese authors, like Ogyū Sorai and Motoori Norinaga. This book analyzes their works in relation to Shizuki’s manuscripts and his Dutch sources, contextualizing Shizuki’s theories and demonstrating their relationship to his sources. The book argues in favor of a new positioning of Shizuki and the other rangakusha within the scholarly environment of Early Modern Japan.Language Use in Past and Presen

A continuous Flaring- to Normal-branch transition in Sco X-1

We report the first resolved rapid transition from a Flaring Branch Oscillation to a Normal Branch Oscillation in the RXTE data of the Z source Sco X-1. The transition took place on a time scale of ~100 seconds and was clearly associated to the Normal Branch-Flaring Branch vertex in the color-color diagram. We discuss the results in the context of the possible association of the Normal Branch Oscillation with other oscillations known both in Neutron-Star and Black-Hole systems, concentrating on the similarities with the narrow 4-6 Hz oscillations observed at high flux in Black-Hole Candidates.Comment: 5 pages, 4 figures, accepted for publication in Astronomy & Astrophysic

Serotonin Trasporter Tracks Similarities Between Sids And Idiopathic Alte

Polymorphisms in the serotonin transporter (5HTT) (SLC6A4 encoding 5HTT) as a predisposing factor in infant death. Considering stric corrispondence between 5HTT and MAOA genotypic and allelic data inIALTE and SIDS, we hypothesize that the two syndromes are different expression of a common ethiopathogenesis

Natural cytotoxicity impairment in familial haemophagocytic lymphohistiocytosis.

Ten children with the characteristic clinical and haematological features of haemophagocytic lymphohistiocytosis are reported. Four patients treated with a combination of drugs comprising etoposide, methotrexate, and steroids were in complete remission after 10 to 30 months. Natural cytotoxic mechanisms including natural killer cell activity, antibody dependent cell mediated cytotoxicity, lymphokine activated killer cell activity, and natural killer cell like activity were persistently absent or severely impaired in these four patients despite their clinical remission. Their parents and one healthy sibling also had impaired natural cytotoxic mechanisms. Constitutional impairment of natural cytotoxic mechanisms could be important in the pathogenesis of haemophagocytic lymphohistiocytosis

Growth hormone therapy and respiratory disorders: Long-term follow-up in PWS children

Context: Adenotonsillar tissue hypertrophy and obstructive sleep apnea have been reported during short-term GH treatment in children with Prader-Willi syndrome (PWS). Objective: We conducted an observational study to evaluate the effects of long-term GH therapy on sleep-disordered breathing and adenotonsillar hypertrophy in children with PWS. Design: This was a longitudinal observational study. PatientsandMethods:Weevaluated 75 children with genetically confirmedPWS,ofwhom50 fulfilled the criteria and were admitted to our study. The patients were evaluated before treatment (t0), after 6 weeks (t1), after 6 months (t2), after 12 months (t3), and yearly (t4-t6) thereafter, for up to 4 years of GH therapy. The central apnea index, obstructive apnea hypopnea index (OAHI), respiratory disturbance index, and minimal blood oxygen saturation were evaluated overnight using polysomnography. We evaluated the adenotonsillar size using a flexible fiberoptic endoscope. Results: The percentage of patients with an OAHI of 1 increased from 3 to 22, 36, and 38 at t1, t4, and t6, respectively (2 12.2; P .05). We observed a decrease in the respiratory disturbance indexfrom1.4 (t0) to 0.8 (t3) (P.05)andthe centralapneaindexfrom1.2 (t0) to 0.1 (t4) (P.0001). We had to temporarily suspend treatment for 3 patients at t1, t4, and t5 because of severe obstructive sleep apnea. The percentage of patients with severe adenotonsillar hypertrophy was significantly higher at t4 and t5 than at t0. The OAHI directly correlated with the adenoid size (adjusted for age) (P .01) but not with the tonsil size and IGF-1 levels. Conclusion: Long-termGHtreatment in patients withPWSis safe; however,werecommend annual polysomnography and adenotonsillar evaluation

What information is available to women regarding coronavirus and childbirth in Italy? A mixed-methods exploration of the web during the COVID-19 lockdown

Problem: The world is fighting against the COVID-19 pandemic and an infodemic; Italy is one of the most severely affected countries. Background: The internet represents a popular source of health information. In Italy, its use amongst pregnant women and new mothers has increased during the lockdown. No research has examined the nationally accessible information related to childbirth in these unprecedented circumstances. Aim: To explore online information accessible to Italian users concerning childbirth and coronavirus-related issues. Methods: A mixed methods exploration of the web was conducted involving searches on Google, peer discussion forums and midwifery association webpages. Data were analysed both quantitatively and qualitatively. A cross-consultation analysis of themes was performed to identify macro categories of information. Findings: A total of 720 results from free searches, 635 interventions from 97 forums and 68 posts from four midwifery association webpages were analysed. Informative/divulging sources were the most prevalent in Google; pregnancy-related topics appeared more in discussion forums and midwifery association webpages. ‘Prevention’; ‘risks and outcomes’; ‘users’ experiences’ and ‘reorganisation of maternity services’ represent the cross-consultation categories of information. Discussion: Google emerges as the main contributor to the infodemic; national systems of alert and ranking of web sources are needed. Women’s pragmatic needs are more likely to be addressed by peer-discussion forums and midwifery association webpages during and after COVID-19. Conclusion: This is the first study to investigate childbirth-related web information during COVID-19 in Italy; findings may impact on education, research and practice

XMM-Newton observations of IGRJ18410-0535: The ingestion of a clump by a supergiant fast X-ray transient

IGRJ18410-0535 is a supergiant fast X-ray transients. This subclass of supergiant X-ray binaries typically undergoes few- hour-long outbursts reaching luminosities of 10^(36)-10^(37) erg/s, the occurrence of which has been ascribed to the combined effect of the intense magnetic field and rotation of the compact object hosted in them and/or the presence of dense structures ("clumps") in the wind of their supergiant companion. IGR J18410-0535 was observed for 45 ks by XMM-Newton as part of a program designed to study the quiescent emission of supergiant fast X-ray transients and clarify the origin of their peculiar X-ray variability. We carried out an in-depth spectral and timing analysis of these XMM-Newton data. IGR J18410-0535 underwent a bright X-ray flare that started about 5 ks after the beginning of the observation and lasted for \sim15 ks. Thanks to the capabilities of the instruments on-board XMM-Newton, the whole event could be followed in great detail. The results of our analysis provide strong convincing evidence that the flare was produced by the accretion of matter from a massive clump onto the compact object hosted in this system. By assuming that the clump is spherical and moves at the same velocity as the homogeneous stellar wind, we estimate a mass and radius of Mcl \simeq1.4\times10^(22) g and Rcl \simeq8\times10^(11) cm. These are in qualitative agreement with values expected from theoretical calculations. We found no evidence of pulsations at \sim4.7 s after investigating coherent modulations in the range 3.5 ms-100 s. A reanalysis of the archival ASCA and Swift data of IGR J18410-0535, for which these pulsations were previously detected, revealed that they were likely to be due to a statistical fluctuation and an instrumental effect, respectively.Comment: Accepted for publication on A&A. V2: Inserted correct version of Fig.1

Design of technology-based rehabilitation pathways: the experience of Santobono-Pausilipon Hospital

The fields of rehabilitation robotics and virtual reality (VR) are becoming a growing area in the clinical rehabilitation of people with motion impairments. These systems have the potential to assess abilities through physiological measurements and modelling activities such as posture, gait, and balance. They can be used as rehabilitative tools by providing patients with task-specific training in a motivating and engaging way too. Although the potential advantages of such systems, until now there is a general limitation of their use in rehabilitative practice. Robotics and VR systems can be challenging, engaging and fun, particularly for children with disabilities, since they are often not very motivated to comply with conventional therapy. The aim of this work is to accurately describe the clinical use of innovative rehabilitative technologies and their use for the development of two technology-based rehabilitation pathways for the treatment of gait disorders following obesity and neurological diseases in treatment of pediatric patients

X-ray Pulsations from the region of the Supergiant Fast X-ray Transient IGR J17544-2619

Phase-targeted RXTE observations have allowed us to detect a transient 71.49 \pm 0.02 s signal that is most likely to be originating from the supergiant fast X-ray transient IGR J17544-2619. The phase-folded light curve shows a possible double-peaked structure with a pulsed flux of ~4.8*10^-12 erg cm^-2 s^-1 (3-10 keV). Assuming the signal to indicate the spin period of the neutron star in the system, the provisional location of IGR J17544-2619 on the Corbet diagram places the system within the classical wind-fed supergiant XRB region. Such a result illustrates the growing trend of supergiant fast X-ray transients to span across both of the original classes of HMXB in Porb - Pspin space.Comment: 7 pages, 6 figures, Accepted for publication in Astronomy and Astrophysics main journa