415 research outputs found
Intervalley-Scattering Induced Electron-Phonon Energy Relaxation in Many-Valley Semiconductors at Low Temperatures
We report on the effect of elastic intervalley scattering on the energy
transport between electrons and phonons in many-valley semiconductors. We
derive a general expression for the electron-phonon energy flow rate at the
limit where elastic intervalley scattering dominates over diffusion. Electron
heating experiments on heavily doped n-type Si samples with electron
concentration in the range m are performed at
sub-1 K temperatures. We find a good agreement between the theory and the
experiment.Comment: v2: Notations changed: --> ,
removed. Eq. (1) changed, Eq. (2) added and complete derivation of Eq. (3)
included. Some further discussion about single vs. many valley added [3rd
paragraph after Eq. (7)]. End notes removed and new reference added [Kragler
and Thomas]. Typos in references correcte
Competing with stationary prediction strategies
In this paper we introduce the class of stationary prediction strategies and
construct a prediction algorithm that asymptotically performs as well as the
best continuous stationary strategy. We make mild compactness assumptions but
no stochastic assumptions about the environment. In particular, no assumption
of stationarity is made about the environment, and the stationarity of the
considered strategies only means that they do not depend explicitly on time; we
argue that it is natural to consider only stationary strategies even for highly
non-stationary environments.Comment: 20 page
Adaptive Mixture Methods Based on Bregman Divergences
We investigate adaptive mixture methods that linearly combine outputs of
constituent filters running in parallel to model a desired signal. We use
"Bregman divergences" and obtain certain multiplicative updates to train the
linear combination weights under an affine constraint or without any
constraints. We use unnormalized relative entropy and relative entropy to
define two different Bregman divergences that produce an unnormalized
exponentiated gradient update and a normalized exponentiated gradient update on
the mixture weights, respectively. We then carry out the mean and the
mean-square transient analysis of these adaptive algorithms when they are used
to combine outputs of constituent filters. We illustrate the accuracy of
our results and demonstrate the effectiveness of these updates for sparse
mixture systems.Comment: Submitted to Digital Signal Processing, Elsevier; IEEE.or
Inhibition in multiclass classification
The role of inhibition is investigated in a multiclass support vector machine formalism inspired by the brain structure of insects. The so-called mushroom bodies have a set of output neurons, or classification functions,
that compete with each other to encode a particular input. Strongly active output neurons depress or inhibit the remaining outputs without knowing which is correct or incorrect. Accordingly, we propose to use a
classification function that embodies unselective inhibition and train it in the large margin classifier framework. Inhibition leads to more robust classifiers in the sense that they perform better on larger areas of appropriate hyperparameters when assessed with leave-one-out strategies. We also show that the classifier with inhibition is a tight bound to probabilistic exponential models and is Bayes consistent for 3-class problems.
These properties make this approach useful for data sets with a limited number of labeled examples. For larger data sets, there is no significant comparative advantage to other multiclass SVM approaches
Inhibition in multiclass classification
The role of inhibition is investigated in a multiclass support vector machine formalism inspired by the brain structure of insects. The so-called mushroom bodies have a set of output neurons, or classification functions,
that compete with each other to encode a particular input. Strongly active output neurons depress or inhibit the remaining outputs without knowing which is correct or incorrect. Accordingly, we propose to use a
classification function that embodies unselective inhibition and train it in the large margin classifier framework. Inhibition leads to more robust classifiers in the sense that they perform better on larger areas of appropriate hyperparameters when assessed with leave-one-out strategies. We also show that the classifier with inhibition is a tight bound to probabilistic exponential models and is Bayes consistent for 3-class problems.
These properties make this approach useful for data sets with a limited number of labeled examples. For larger data sets, there is no significant comparative advantage to other multiclass SVM approaches
Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya
Background:
The relationship between glucose-6-phosphate dehydrogenase (G6PD) deficiency and clinical phenomena such as primaquine-sensitivity and protection from severe malaria remains poorly defined, with past association studies yielding inconsistent and conflicting results. One possibility is that examination of a single genetic variant might underestimate the presence of true effects in the presence of unrecognized functional allelic diversity.
Methods:
We systematically examined this possibility in Kenya, conducting a fine-mapping association study of erythrocyte G6PD activity in 1828 Kenyan children across 30 polymorphisms at or around the G6PD locus.
Results:
We demonstrate a strong functional role for c.202G>A (rs1050828), which accounts for the majority of variance in enzyme activity observed (P=1.5 × 10-200, additive model). Additionally, we identify other common variants that exert smaller, intercorrelated effects independent of c.202G>A, and haplotype analyses suggest that each variant tags one of two haplotype motifs that are opposite in sequence identity and effect direction. We posit that these effects are of biological and possible clinical significance, specifically noting that c.376A>G (rs1050829) augments 202AG heterozygote risk for deficiency trait by two-fold (OR = 2.11 [1.12 - 3.84], P=0.014).
Conclusions:
Our results suggest that c.202G>A is responsible for the majority of the observed prevalence of G6PD deficiency trait in Kenya, but also identify a novel role for c.376A>G as a genetic modifier which marks a common haplotype that augments the risk conferred to 202AG heterozygotes, suggesting that variation at both loci merits consideration in genetic association studies probing G6PD deficiency-associated clinical phenotypes. </p
Competitive portfolio selection using stochastic predictions
We study a portfolio selection problem where a player attempts to maximise a utility function that represents the growth rate of wealth. We show that, given some stochastic predictions of the asset prices in the next time step, a sublinear expected regret is attainable against an optimal greedy algorithm, subject to tradeoff against the \accuracy" of such predictions that learn (or improve) over time. We also study the effects of introducing transaction costs into the model
Higher education and unemployment in Europe : an analysis of the academic subject and national effects
This paper examines the impact of an academic degree and field of study on short and long-term unemployment across Europe (EU15). Labour Force Survey (LFS) data on over half a million individuals are utilised for that purpose. The harmonized LFS classification of level of education and field of study overcomes past problems of comparability across Europe. The study analyses (i) the effect of an academic degree at a European level, (ii) the specific effect of 14 academic subjects and (iii) country specific effects. The results indicate that an academic degree is more effective on reducing the likelihood of short-term than long-term unemployment. This general pattern even though it is observed for most of the academic subjects its levels show significant variation across disciplines and countries
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