90 research outputs found
MOLDE PARA LA FABRICACIÓN DE MANGOS DE CAZO CON LA REPRESENTACIÓN CIBELES-ATTIS HALLADO EN LOS ALFARES DE VAREA (LA RIOJA)
Damos a conocer aquí el hallazgo de un molde de mango de cazo, producto de prospecciones de superficie habido en el área riojana del Ebro medio, concretamente en los alfares de una mansión de la vía 1 del Itinerario de Antonino: Vareia.
LA CUEVA DE CIENTA (ARNEDO-LA RIOJA)
Localization and description. There are archaeological remains in front of the cliff where the cave was excavated whose excavation and study are worth while. The most outstanding characteristics are: the shape of the alveolus, which are a type of spherical caps but don't have sufficient base for an animal to nest. There are three situated in the main place of te principal front that have also excavated a sort of beard. There are graffiti in the spaces between the alveolus, at least two of which are Christian. With these characteristics this cave can only be a "columbarium".Localización y descripción. Restos arqueológicos delante de la peña en la que está horadada la cueva, que valdría la pena excavar y estudiar. Características más destacables: forma de los alvéolos, que son a modo de casquetes esféricos y no tienen base suficiente para que en ellos pueda anidar animal alguno. Hay tres que tienen vaciada lo que podríamos denominar la «barba». Grafitos por los espacios entre los alvéolos, de los que al menos dos son inscripciones cristianas. Con tales características esta cueva sólo puede ser un «columbario»
La cueva de Páceta: Castro Bilibio (La Rioja) – ¿Un oratorio rupestre?
Descripción de una cueva labrada, situada al pie del risco de Bilibio, en el que según la tradición vivió San Felices, y que interpretamos como monacal por su tipología y rasgos diferenciadores que entendemos la adornan
A new alternative for obtaining nanocrystalline bioactive coatings: study of hydroxyapatite deposition mechanisms by cold gas praying
The present article is intended to study the deposition mechanisms of bioactive hydroxyapatite (HA) particles by means of Cold Gas Spraying (CGS). A comparison of the deposition on two different substrates (Ti6Al4V and Al7075T6) and different particle sizes is presented. Although this is a more specific deposition technique for ductile materials, it is here shown that, in certain conditions, ceramic deposition is possible despite the inherent low ductility. The resulting internal structure and the features at the particle-substrate interface are discussed in view of Transmission Electron Microscopy examinations of a Focused Ion Beam lift-out prepared sample. Mainly, under shock compressive loading, the porous sintered powder proceeds through pore collapse, fragmentation and densification as well as grain refinement. The process is described through different plastic mechanisms in ceramics. This opens a new alternative route to produce nanocrystalline HA coatings through a cost-effective proces
Dense nanostructured calcium phosphate coating on titanium by cold spray
This article deals with the understanding of building-up mechanisms of bioactive nanocrystalline hydroxyapatite coatings by Cold Spray, revealing very promising results in contrast to more conventional techniques such as Plasma Spray. A full characterization of feedstock and coatings is provided. The agglomerated structure of the powder proved to be suitable to obtain successfully thick hydroxyapatite coatings. A crystallite size below similar to 20 nm in the powder and the as-sprayed coatings is calculated by the Rietveld X-ray refinement method and agreed by Transmission Electron Microscopy. Some wipe tests were carried out on Ti6Al4V substrates in order to study the deposition of single particles and the nanoscale features were evaluated. The resulting structure indicates that there is no delimitation of particle boundaries and the overall coating has been formed by effective compaction of the original nanocrystallites, leading to consistent and consolidated layers
Renal Function Impact in the Prognostic Value of Galectin-3 in Acute Heart Failure
[Abstract] Introduction: Galectin-3 (Gal-3) is an inflammatory marker associated with the development and progression of heart failure (HF). A close relationship between Gal-3 levels and renal function has been observed, but data on their interaction in patients with acute HF (AHF) are scarce. We aim to assess the prognostic relationship between renal function and Gal-3 during an AHF episode.
Materials and methods: This is an observational, prospective, multicenter registry of patients hospitalized for AHF. Patients were divided into two groups according to estimated glomerular filtration rate (eGFR): preserved renal function (eGFR ≥ 60 mL/min/1.73 m2) and renal dysfunction (eGFR <60 mL/min/1.73 m2). Cox regression analysis was performed to evaluate the association between Gal-3 and 12-month mortality.
Results: We included 1,201 patients in whom Gal-3 values were assessed at admission. The median value of Gal-3 in our population was 23.2 ng/mL (17.3-32.1). Gal-3 showed a negative correlation with eGFR (rho = -0.51; p < 0.001). Gal-3 concentrations were associated with higher mortality risk in the multivariate analysis after adjusting for eGFR and other prognostic variables [HR = 1.010 (95%-CI: 1.001-1.018); p = 0.038]. However, the prognostic value of Gal-3 was restricted to patients with renal dysfunction [HR = 1.010 (95%-CI: 1.001-1.019), p = 0.033] with optimal cutoff point of 31.5 ng/mL, with no prognostic value in the group with preserved renal function [HR = 0.990 (95%-CI: 0.964-1.017); p = 0.472].
Conclusions: Gal-3 is a marker of high mortality in patients with acute HF and renal dysfunction. Renal function influences the prognostic value of Gal-3 levels, which should be adjusted by eGFR for a correct interpretation.Grant No. RD06-0003-0000
Grant No. RD12/0042/000
A 3-biomarker 2-point-based risk stratification strategy in acute heart failure
[Abstract] Introduction and Objectives: Most multi-biomarker strategies in acute heart failure (HF) have only measured biomarkers in a single-point time. This study aimed to evaluate the prognostic yielding of NT-proBNP, hsTnT, Cys-C, hs-CRP, GDF15, and GAL-3 in HF patients both at admission and discharge.
Methods: We included 830 patients enrolled consecutively in a prospective multicenter registry. Primary outcome was 12-month mortality. The gain in the C-index, calibration, net reclassification improvement (NRI), and integrated discrimination improvement (IDI) was calculated after adding each individual biomarker value or their combination on top of the best clinical model developed in this study (C-index 0.752, 0.715–0.789) and also on top of 4 currently used scores (MAGGIC, GWTG-HF, Redin-SCORE, BCN-bioHF).
Results: After 12-month, death occurred in 154 (18.5%) cases. On top of the best clinical model, the addition of NT-proBNP, hs-CRP, and GDF-15 above the respective cutoff point at admission and discharge and their delta during compensation improved the C-index to 0.782 (0.747–0.817), IDI by 5% (p < 0.001), and NRI by 57% (p < 0.001) for 12-month mortality. A 4-risk grading categories for 12-month mortality (11.7, 19.2, 26.7, and 39.4%, respectively; p < 0.001) were obtained using combination of these biomarkers.
Conclusion: A model including NT-proBNP, hs-CRP, and GDF-15 measured at admission and discharge afforded a mortality risk prediction greater than our clinical model and also better than the most currently used scores. In addition, this 3-biomarker panel defined 4-risk categories for 12-month mortality.Instituto de Salud Carlos III; RD06-0003-0000Instituto de Salud Carlos III; RD12/0042/000
El poblado medieval de Aguilar, una aldea de Calahorra
En estos últimos años, la extracción de áridos en la zona del Cascajo (Calahorra, La Rioja), ha supuesto la destrucción de restos arqueológicos correspondientes a cinco asentamientos de diferentes épocas. El último de ellos, la aldea medieval de Aguilar, un poblado dependiente de Calahorra durante la Baja Edad Media, y documentado desde el año 1287 hasta su desaparición a finales del siglo XV
Toponimia menor de Calahorra y su delimitación, a partir de un documento conservado en la Comunidad General de Regadíos de Calahorra (La Rioja)
This paper presents the minor toponymy of a considerable part of the municipal district of Calahorra, obtained from graphic documentation about the land registry of 1960 preserved in Calahorra General Community of Irrigation (La Rioja). The purpose of this work is not to analyse the origen and history of the various names reported there but document them, that is to say to situate them properly in the cartography and provide graphic documentation about their delimitation. Toponymy, in the widest connotation of the term, both mayor and minor, it is not just part of our collective memories, but also an important cultural heritage that must be reserved and disseminated.Damos a conocer la toponimia menor y su delimitación en la mayor parte del término municipal de Calahorra, a partir de la documentación gráfica conservada en la Comunidad General de Regadíos de Calahorra sobre el catastro de rústica de 1960. No es objetivo de este trabajo analizar el origen y la historia de los diferentes nombres aportados sino documentarlos, ubicarlos correctamente sobre la cartografía y aportar documentación gráfica con su delimitación. La toponimia en su más amplia acepción, tanto mayor como menor, no es solo una parte de nuestra memoria colectiva sino también un importante patrimonio cultural a conservar y dar a conocer
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