UK regional scale modelling of natural geohazards and climate change

For over 10 years, the British Geological Survey (BGS) has been investigating geotechnical and mineralogical factors controlling volume change behaviour of UK clay soils and mudrocks. A strong understanding of the relationship between these parameters and the clays' shrink-swell properties has been developed. More recently, partly resulting from concerns of users of this knowledge, a study of the relationships between climate change and shrink-swell behaviour over the last 30 years has been carried out. Information on subsidence insurance claims has been provided by the Association of British Insurers (ABI) and the UK Meteorological Office (UKMO) historical climate station data has also been utilised. This is being combined with the BGS's GeoSure national geohazard data, to build a preliminary GIS model to provide an understanding of the susceptibility of the Tertiary London Clay to climate change. This paper summarises the data analysis and identifies future work for model construction and refinement

New Fundamental dHvA Frequency in Canonical Low-Dimensional Fermi Liquids

We show that a new fundamental period $P_{f}$ of dHvA oscillations, which appears along with other ``forbidden'' combination frequencies in a multi-band canonical Fermi-liquid, is very robust with respect to a finite smearing of Landau levels and a background of non-quantized states. We analyse the possibility of measuring small Fermi surface pockets with the use of the ``forbidden'' frequencies.Comment: 10 pages, RevTeX 3.0, with 2 PS Figure

Steklov problem on differential forms

In this paper we study spectral properties of Dirichlet-to-Neumann map on differential forms obtained by a slight modification of the definition due to Belishev and Sharafutdinov. The resulting operator $\Lambda$ is shown to be self-adjoint on the subspace of coclosed forms and to have purely discrete spectrum there.We investigate properies of eigenvalues of $\Lambda$ and prove a Hersch-Payne-Schiffer type inequality relating products of those eigenvalues to eigenvalues of Hodge Laplacian on the boundary. Moreover, non-trivial eigenvalues of $\Lambda$ are always at least as large as eigenvalues of Dirichlet-to-Neumann map defined by Raulot and Savo. Finally, we remark that a particular case of $p$-forms on the boundary of $2p+2$-dimensional manifold shares a lot of important properties with the classical Steklov eigenvalue problem on surfaces.Comment: 18 page

STAT1 activation in association with JAK2 exon 12 mutations

La inclusión de la perspectiva de género en la actividad jurisdiccional es una demanda sostenida de los colectivos feministas y de mujeres, dado que las sentencias tienen un poder performativo y envían un mensaje a la sociedad: “[…] tienen un poder individual y colectivo que impactan en la vida de las personas y conforman la identidad del poder judicial como un actor imprescindible en la construcción de un Estado democrático de derecho” (Suprema Corte de Justicia de la Nación, 2013:7). La incorporación de la perspectiva de género viene a garantizar la igualdad de posiciones (Kessler, 2014) entre mujeres y varones como una meta, trascendiendo la mera igualdad de oportunidades que hasta el presente se ha demostrado insuficiente para que las mujeres consigamos una ciudadanía plena. Al momento de incorporar la perspectiva de género en las sentencias, quienes juzgan deben tener presente en primer lugar, el impacto diferenciado de las normas en base al sexo de las personas. En segundo lugar, la interpretación y aplicación de las leyes en relación con (y en base a) estereotipos de género. Si, por ejemplo, quienes imparten justicia no tienen presentes los estereotipos de género vigentes detrás de las violaciones a los derechos humanos de las mujeres, si no los detectan ni cuestionan, entonces los reproducen. Tal como sostiene Scott (1996) el género es una categoría imprescindible para el análisis social. En tercer lugar, al momento del juzgamiento, se deben tener en cuenta las exclusiones legitimadas por la ley por pensar el mundo en términos binarios y androcéntricos; en cuarto lugar, la distribución no equitativa de recursos y poder que opera entre varones y mujeres en el marco de una organización social patriarcal, y, por último, el trato diferenciado por género legitimado por las propias leyes.Eje 3: Tramas violentas y espacios de exclusión.Instituto de Cultura Jurídic

Increasing road network resilience to the impacts of ground movement due to climate change – a case study from Lincolnshire, United Kingdom

The UK road network is deteriorating due to ageing infrastructure, climate change and increasing traffic. Due to community and economic reliance on a functioning road system, there is an urgent requirement to build resilience. The roads of south Lincolnshire have high susceptibility to ground movement due to the underlying geology. Deposits such as peat, tidal flat deposits, and alluvium have a high susceptibility to compress, particularly when loaded, or through loss of water content driven by climate change or lowering of water in drainage channels. The shallow foundations of Lincolnshire's rural evolved roads, originating from old mud tracks, are poorly constructed, increasing their vulnerability to movement. Types of damage include longitudinal cracking, edge failure, and uneven long section profiles. Through knowledge exchange, data sharing and collaboration between the British Geological Survey and Lincolnshire County Council, a direct relationship between road condition and geohazard susceptibility has been demonstrated; showing compressible ground has a greater correlation with road damage than originally considered. This suggests improved understanding of the relationships between the geological, climatic, and anthropogenic driving forces on ground movement and road damage enables more informed repair prioritisation, decision support, and improved bespoke road repair practices, increasing future resilience of road networks

Quantization on Curves

Deformation quantization on varieties with singularities offers perspectives that are not found on manifolds. Essential deformations are classified by the Harrison component of Hochschild cohomology, that vanishes on smooth manifolds and reflects information about singularities. The Harrison 2-cochains are symmetric and are interpreted in terms of abelian $*$-products. This paper begins a study of abelian quantization on plane curves over \Crm, being algebraic varieties of the form R2/I where I is a polynomial in two variables; that is, abelian deformations of the coordinate algebra C[x,y]/(I). To understand the connection between the singularities of a variety and cohomology we determine the algebraic Hochschild (co-)homology and its Barr-Gerstenhaber-Schack decomposition. Homology is the same for all plane curves C[x,y]/(I), but the cohomology depends on the local algebra of the singularity of I at the origin.Comment: 21 pages, LaTex format. To appear in Letters Mathematical Physic

A composite measure of cognitive and functional progression in Alzheimer's disease: Design of the Capturing Changes in Cognition study

markdownabstract__Introduction__ Cognitive testing in Alzheimer's disease (AD) is essential for establishing diagnosis, monitoring progression, and evaluating treatments. Assessments should ideally be brief, reliable, valid, and reflect clinically meaningful changes. There is a lack of instruments that meet all these criteria. In the Capturing Changes in Cognition (Catch-Cog) study, we seek to correct these deficiencies through the development and validation of a composite measure combining cognition and function: the cognitive-functional composite (CFC). We expect that the CFC is able to detect clinically relevant changes over time in early dementia stages of AD. __Methods/Design__ We will include patients (n = 350) with mild cognitive impairment or mild dementia due to AD from memory clinics in the Netherlands and the United Kingdom. We will include cognitively healthy volunteers (n = 30) as a control group. The CFC is based on the “cognitive composite” and the Amsterdam instrumental activities of daily living questionnaire. We will investigate test–retest reliability with baseline and 2- to 3-week follow-up assessments (n = 50 patients and n = 30 healthy controls). We will involve experts and participants to evaluate the initial feasibility and refine the CFC if needed. Subsequently, we will perform a longitudinal construct validation study in a prospective cohort (n = 300) with baseline, 3-, 6-, and 12-month follow-up assessments. The main outcome is cognitive and functional progression measured by the CFC. Reference measures for progression include traditional cognitive and functional tests, disease burden measures, and brain imaging methods. Using linear mixed modeling, we will investigate longitudinal changes on the CFC and relate these to the reference measures. Using linear regression analyses, we will evaluate the influence of possible confounders such as age, gender, and education on the CFC. __Discussion__ By performing an independent longitudinal construct validation, the Catch-Cog study of the novel CFC will contribute to the improvement of disease monitoring and treatment evaluation in early dementia stages of AD

La relación personal en el tratamiento de la diversidad

El autor centra su aportación en diferentes características de los organismos vivos, para incorporarlas a las perspectivas interpretativas y operativas, y de los métodos actuales de intervención educativa. En el texto también se trata el enfoque positivo desde la dimensión técnica y no «voluntarista», teniendo en cuenta que los especialistas que adoptan la perspectiva del enfoque positivo dan mucha importancia al tema de la calidad de vida.L'autor centra la seva aportació en diferents característiques dels organismes vius, per incorporar- les a les perspectives interpretatives i operatives, i dels mètodes actuals d'intervenció educativa. Al text també es tracta l'enfocament positiu des de la seva dimensió tècnica i no «voluntarista», tenint en compte que els especialistes que adopten la perspectiva de l'enfocament positiu donen molta importància al tema de la qualitat de vida.The author focuses on the different characteristics of the alive organisms in order to include them into the interpretative and operative views of the current methods of educational intervention. He also deals with the positive focus, from the technical and «no voluntary» dimension, taking into account that those specialists having this kind of view do emphasize a lot on the quality of life issue

The KMOS Deep Survey (KDS) – I. Dynamical measurements of typical star-forming galaxies at z ≃ 3.5

We present dynamical measurements from the KMOS (K-band Multi-Object Spectrograph) Deep Survey (KDS), which is comprised of 77 typical star-forming galaxies at z z ≃ 3.5 in the mass range 9.0 1), with the sample average VC/σint value much smaller than at lower redshift. After carefully selecting comparable star-forming samples at multiple epochs, we find that the rotation-dominated fraction evolves with redshift with a z−0.2 dependence. The rotation-dominated KDS galaxies show no clear offset from the local rotation velocity-stellar mass (i.e. VC − M⋆) relation, although a smaller fraction of the galaxies are on the relation due to the increase in the dispersion-dominated fraction. These observations are consistent with a simple equilibrium model picture, in which random motions are boosted in high-redshift galaxies by a combination of the increasing gas fractions, accretion efficiency, specific star-formation rate and stellar feedback and which may provide significant pressure support against gravity on the galactic disk scale