366 research outputs found

    Coordinate shadows of semi-definite and Euclidean distance matrices

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    We consider the projected semi-definite and Euclidean distance cones onto a subset of the matrix entries. These two sets are precisely the input data defining feasible semi-definite and Euclidean distance completion problems. We classify when these sets are closed, and use the boundary structure of these two sets to elucidate the Krislock-Wolkowicz facial reduction algorithm. In particular, we show that under a chordality assumption, the "minimal cones" of these problems admit combinatorial characterizations. As a byproduct, we record a striking relationship between the complexity of the general facial reduction algorithm (singularity degree) and facial exposedness of conic images under a linear mapping.Comment: 21 page

    Bad semidefinite programs: they all look the same

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    Conic linear programs, among them semidefinite programs, often behave pathologically: the optimal values of the primal and dual programs may differ, and may not be attained. We present a novel analysis of these pathological behaviors. We call a conic linear system Ax<=bAx <= b {\em badly behaved} if the value of supAx<=b\sup { | A x <= b } is finite but the dual program has no solution with the same value for {\em some} c.c. We describe simple and intuitive geometric characterizations of badly behaved conic linear systems. Our main motivation is the striking similarity of badly behaved semidefinite systems in the literature; we characterize such systems by certain {\em excluded matrices}, which are easy to spot in all published examples. We show how to transform semidefinite systems into a canonical form, which allows us to easily verify whether they are badly behaved. We prove several other structural results about badly behaved semidefinite systems; for example, we show that they are in NPcoNPNP \cap co-NP in the real number model of computing. As a byproduct, we prove that all linear maps that act on symmetric matrices can be brought into a canonical form; this canonical form allows us to easily check whether the image of the semidefinite cone under the given linear map is closed.Comment: For some reason, the intended changes between versions 4 and 5 did not take effect, so versions 4 and 5 are the same. So version 6 is the final version. The only difference between version 4 and version 6 is that 2 typos were fixed: in the last displayed formula on page 6, "7" was replaced by "1"; and in the 4th displayed formula on page 12 "A_1 - A_2 - A_3" was replaced by "A_3 - A_2 - A_1

    Nanofibrous solid dosage form of living bacteria prepared by electrospinning

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    The aim of this work was to investigate the suitability of electrospinning for biodrug delivery and to develop an electrospinning-based method to produce vaginal drug delivery systems. Lactobacillus acidophilus bacteria were encapsulated into nanofibers of three different polymers (polyvinyl alcohol and polyvinylpyrrolidone with two different molar masses). Shelf life of the bacteria could be enhanced by the exclusion of water and by preparing a solid dosage form, which is an advantageous and patient-friendly way of administration. The formulations were stored at –20, 7 and 25°C, respectively. Viability testing showed that the nanofibers can provide long term stability for huge amounts of living bacteria if they are kept at (or below) 7°C. Furthermore, all kinds of nanowebs prepared in this work dissolved instantly when they got in contact with water, thus the developed biohybrid nanowebs can provide new potential ways for curing bacterial vaginosis

    Selecting appropriate methods of knowledge synthesis to inform biodiversity policy

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    Responding to different questions generated by biodiversity and ecosystem services policy or management requires different forms of knowledge (e.g. scientific, experiential) and knowledge synthesis. Additionally, synthesis methods need to be appropriate to policy context (e.g. question types, budget, timeframe, output type, required scientific rigour). In this paper we present a range of different methods that could potentially be used to conduct a knowledge synthesis in response to questions arising from knowledge needs of decision makers on biodiversity and ecosystem services policy and management. Through a series of workshops attended by natural and social scientists and decision makers we compiled a range of question types, different policy contexts and potential methodological approaches to knowledge synthesis. Methods are derived from both natural and social sciences fields and reflect the range of question and study types that may be relevant for syntheses. Knowledge can be available either in qualitative or quantitative form and in some cases also mixed. All methods have their strengths and weaknesses and we discuss a sample of these to illustrate the need for diversity and importance of appropriate selection. To summarize this collection, we present a table that identifies potential methods matched to different combinations of question types and policy contexts, aimed at assisting teams undertaking knowledge syntheses to select appropriate methods

    Riparian thermal conditions across a mixed rural and urban landscape

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    Riparian corridors have the potential to function as thermal refuges, moderating extremes of local temperature variation. However, although demonstrated at individual sites, and over short periods, the consistency of this effect at wider temporal and spatial scales is poorly understood. The aim of this study is to assess the temperature differences between riparian corridors and adjacent non-riparian habitats and to explore the influence of environmental characteristics on these differences. Air temperature was monitored hourly at 20 paired locations (riparian and non-riparian) for two consecutive years. Urban index and canopy cover were characterised by calculating the percentage of impervious surface area and tree canopy cover within a 100 m radius from the centre of each sampling site. Canopy cover reduced summer thermal stresses in both urban and rural areas whereas high urban index tended to increase the daily thermal indices. Rivers had a significant mitigating effect on the urban riparian thermal condition, particularly in extreme hot weather. Riparian corridors were generally 1 °C cooler than non-riparian locations in summer and could be up to 3 °C cooler at some sites in extreme hot weather. Furthermore, riparian corridors at some sites were warmer than non-riparian locations in winter. These findings suggest that the proximity of rivers can modify riparian thermal environments, potentially reducing the heat stress of riparian corridors across landscapes

    Proanthocyanidin to prevent formation of the reexpansion pulmonary edema

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    <p>Abstract</p> <p>Background</p> <p>We aimed to investigate the preventive effect of Proanthocyanidine (PC) in the prevention of RPE formation.</p> <p>Methods</p> <p>Subjects were divided into four groups each containing 10 rats. In the Control Group (CG): RPE wasn't performed. Then subjects were followed up for three days and they were sacrificed after the follow up period. Samplings were made from tissues for measurement of biochemical and histopathologic parameters. In the Second Group (PCG): The same protocol as CG was applied, except the administration of PC to the subjects. In the third RPE Group (RPEG): Again the same protocol as CG was applied, but as a difference, RPE was performed. In the Treatment Group (TG): The same protocol as RPEG was applied except the administration of PC to the subjects.</p> <p>Results</p> <p>In RPEG group, the most important histopathological finding was severe pulmonary edema with alveolar damage and acute inflammatory cells. These findings were less in the TG group. RPE caused increased MDA levels, and decreased GPx, SOD and CAT activity significantly in lung tissue.</p> <p>Conclusion</p> <p>PC decreased MDA levels. Oxidative stress plays an important role in pathophysiology of RPE and PC treatment was shown to be useful to prevent formation of RPE.</p
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