24 research outputs found

    La reparaciĂłn econĂłmica a la vĂ­ctima en el sistema de justicia

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    En este libro se recogen las investigaciones llevadas a cabo en el marco de los Trabajos Fin de Grado de la Universidad Carlos III de Madrid en los dobles grados de Derecho y AdministraciĂłn de Empresas, Derecho y EconomĂ­a durante los cursos 2015/16 y 2016/17. El objetivo principal es evaluar la eficacia de la reparaciĂłn econĂłmica a la vĂ­ctima. Para ello, se realizĂł un estudio de campo de las ejecutorias en los Juzgados de lo Penal y la Audiencia Provincial de Madrid en dos etapas, octubre de 2015 y octubre de 2016, , excluyendo delitos menores y delitos relacionados con delitos de trĂĄnsito y violencia de gĂ©nero, asĂ­ como aquellos donde no hubiera vĂ­ctima.Este trabajo ha sido subvencionado en parte por los proyectos DER2015-66435-P y MTM2014-56535-R, Ministerio de EconomĂ­a y Competitividad, y se enmarca en el Proyecto innovaciĂłn docente de la Universidad Carlos III de Madrid titulado Eficacia y Eficiencia de la Justicia, curso 2016/2017.PrĂłlogo / Daniel Peña (pp. 19-20). -- La ineficacia del sistema español en la compensaciĂłn a travĂ©s del proceso / Helena Soleto y Aurea GranĂ© (pp. 23-97). -- Asistencia jurĂ­dica y turno de oficio para la vĂ­ctima / Alicia Calvo BarcelĂł (pp. 101-138). -- Competencia judicial en ejecuciĂłn penal / Alberto RodrĂ­guez Abad (pp. 141-175). -- El fiscal en la ejecuciĂłn / MarĂ­a GarcĂ­a Navarro (pp. 177-214). -- La participaciĂłn de la vĂ­ctima en la ejecuciĂłn / Sara GonzĂĄlez PĂ©rez (pp. 215-247). -- InvestigaciĂłn patrimonial del condenado / Radad Sennouni El Harti (pp. 249-277). -- La suspensiĂłn de la pena privativa y libertad condicional / Sara JimĂ©nez Olbea (pp. 281-306). -- La insolvencia del condenado / Catalina GuzmĂĄn GuzmĂĄn (pp. 307-324). -- Eficacia del pago y percepciĂłn de impunidad: consecuencias de la reparaciĂłn en el condenado / Rosa GonzĂĄlez Espejo (pp. 325-342). -- Delitos contra la libertad sexual / MarĂ­a BelĂ©n Combarros GĂłmez (pp. 345-386). -- La vĂ­ctima del delito de trata de seres humanos e inmigraciĂłn ilegal / Eduardo Sagra GonzĂĄlez (pp. 387-407). -- La reparaciĂłn en violencia de gĂ©nero / Marina GarcĂ­a-Navas GĂłmez (pp. 409-439). -- ReparaciĂłn en delitos contra la AdministraciĂłn PĂșblica / Irea RiobĂł Mayo (pp. 441-459). -- La reparaciĂłn econĂłmica en el caso Madrid Arena / LucĂ­a Gimeno Malumbres (pp. 461-487). -- La reparaciĂłn en el proceso de menores / Miriam LĂłpez-Terradas Paniagua (pp. 489-513). -- La atenuante por reparaciĂłn del daño / Adriana Noel Afonso Carracedo (pp. 517-540). -- ReparaciĂłn y modelos de justicia reparativa / Victoria MartĂ­nez MartĂ­nez (pp. 541-567). -- Elementos bĂĄsicos de justicia restaurativa / Mireia Galindo Perpiñån (pp. 569-614). -- El acuerdo de reparaciĂłn en la justicia reparativa / Ainhoa Berrocal Cañadas (pp. 615-634). -- La indemnizaciĂłn a las vĂ­ctimas en el Derecho comparado / Alba Peña DĂ­az (pp. 637-650). -- Las indemnizaciones de la Ley 35/1995 / Inmaculada RamĂ­rez RodrĂ­guez (pp. 651-702). -- El pago de indemnizaciones por el Estado en terrorismo / Ana PĂ©rez CampĂłn (pp. 703-734)

    Jardins per a la salut

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    Facultat de FarmĂ cia, Universitat de Barcelona. Ensenyament: Grau de FarmĂ cia. Assignatura: BotĂ nica farmacĂšutica. Curs: 2014-2015. Coordinadors: Joan Simon, CĂšsar BlanchĂ© i Maria Bosch.Els materials que aquĂ­ es presenten sĂłn el recull de les fitxes botĂ niques de 128 espĂšcies presents en el JardĂ­ Ferran Soldevila de l’Edifici HistĂČric de la UB. Els treballs han estat realitzats manera individual per part dels estudiants dels grups M-3 i T-1 de l’assignatura BotĂ nica FarmacĂšutica durant els mesos de febrer a maig del curs 2014-15 com a resultat final del Projecte d’InnovaciĂł Docent «Jardins per a la salut: aprenentatge servei a BotĂ nica farmacĂšutica» (codi 2014PID-UB/054). Tots els treballs s’han dut a terme a travĂ©s de la plataforma de GoogleDocs i han estat tutoritzats pels professors de l’assignatura. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autĂČnom i col·laboratiu en BotĂ nica farmacĂšutica. TambĂ© s’ha pretĂšs motivar els estudiants a travĂ©s del retorn de part del seu esforç a la societat a travĂ©s d’una experiĂšncia d’Aprenentatge-Servei, deixant disponible finalment el treball dels estudiants per a poder ser consultable a travĂ©s d’una Web pĂșblica amb la possibilitat de poder-ho fer in-situ en el propi jardĂ­ mitjançant codis QR amb un smartphone

    Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections

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    IMPORTANCE The consumption of broad-spectrum drugs has increased as a consequence of the spread of multidrug-resistant (MDR) Escherichia coli. Finding alternatives for these infections is critical, for which some neglected drugs may be an option. OBJECTIVE To determine whether fosfomycin is noninferior to ceftriaxone or meropenem in the targeted treatment of bacteremic urinary tract infections (bUTIs) due to MDR E coli. DESIGN, SETTING, AND PARTICIPANTS This multicenter, randomized, pragmatic, open clinical trial was conducted at 22 Spanish hospitals from June 2014 to December 2018. Eligible participants were adult patients with bacteremic urinary tract infections due to MDR E coli; 161 of 1578 screened patients were randomized and followed up for 60 days. Data were analyzed in May 2021. INTERVENTIONS Patients were randomized 1 to 1 to receive intravenous fosfomycin disodium at 4 g every 6 hours (70 participants) or a comparator (ceftriaxone or meropenem if resistant; 73 participants) with the option to switch to oral fosfomycin trometamol for the fosfomycin group or an active oral drug or pa renteral ertapenem for the comparator group after 4 days. MAIN OUTCOMES AND MEASURES The primary outcome was clinical and microbiological cure (CMC) 5 to 7 days after finalization of treatment; a noninferiority margin of 7% was considered. RESULTS Among 143 patients in the modified intention-to-treat population (median [IQR] age, 72 [62-81] years; 73 [51.0%] women), 48 of 70 patients (68.6%) treated with fosfomycin and 57 of 73 patients (78.1%) treated with comparators reached CMC (risk difference, -9.4 percentage points; 1-sided 95% CI, -21.5 to infinity percentage points; P = .10). While clinical or microbiological failure occurred among 10 patients (14.3%) treated with fosfomycin and 14 patients (19.7%) treated with comparators (risk difference, -5.4 percentage points; 1-sided 95% CI. -infinity to 4.9; percentage points; P = .19), an increased rate of adverse event-related discontinuations occurred with fosfomycin vs comparators (6 discontinuations [8.5%] vs 0 discontinuations; P = .006). In an exploratory analysis among a subset of 38 patients who underwent rectal colonization studies, patients treated with fosfomycin acquired a new ceftriaxone-resistant or meropenem-resistant gram-negative bacteria at a decreased rate compared with patients treated with comparators (0 of 21 patients vs 4 of 17 patients [23.5%]; 1-sided P = .01). CONCLUSIONS AND RELEVANCE This study found that fosfomycin did not demonstrate noninferiority to comparators as targeted treatment of bUTI from MDR E coli; this was due to an increased rate of adverse event-related discontinuations. This finding suggests that fosfomycin may be considered for selected patients with these infections

    CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3

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    ObjectivesCARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E. coli (CP-Eco) to determine their incidence, geographical distribution, phylogeny, and resistance mechanisms in Spain.MethodsIn total, 71 hospitals, representing all 50 Spanish provinces, collected the first 10 isolates per hospital (February to May 2019); CPE isolates were first identified according to EUCAST (meropenem MIC > 0.12 mg/L with immunochromatography, colorimetric tests, carbapenem inactivation, or carbapenem hydrolysis with MALDI-TOF). Prevalence and incidence were calculated according to population denominators. Antibiotic susceptibility testing was performed using the microdilution method (EUCAST). All 403 isolates collected were sequenced for high-resolution single-nucleotide polymorphism (SNP) typing, core genome multilocus sequence typing (cgMLST), and resistome analysis.ResultsIn total, 377 (93.5%) CP-Kpn and 26 (6.5%) CP-Eco isolates were collected from 62 (87.3%) hospitals in 46 (92%) provinces. CP-Kpn was more prevalent in the blood (5.8%, 50/853) than in the urine (1.4%, 201/14,464). The cumulative incidence for both CP-Kpn and CP-Eco was 0.05 per 100 admitted patients. The main carbapenemase genes identified in CP-Kpn were blaOXA–48 (263/377), blaKPC–3 (62/377), blaVIM–1 (28/377), and blaNDM–1 (12/377). All isolates were susceptible to at least two antibiotics. Interregional dissemination of eight high-risk CP-Kpn clones was detected, mainly ST307/OXA-48 (16.4%), ST11/OXA-48 (16.4%), and ST512-ST258/KPC (13.8%). ST512/KPC and ST15/OXA-48 were the most frequent bacteremia-causative clones. The average number of acquired resistance genes was higher in CP-Kpn (7.9) than in CP-Eco (5.5).ConclusionThis study serves as a first step toward WGS integration in the surveillance of carbapenemase-producing Enterobacterales in Spain. We detected important epidemiological changes, including increased CP-Kpn and CP-Eco prevalence and incidence compared to previous studies, wide interregional dissemination, and increased dissemination of high-risk clones, such as ST307/OXA-48 and ST512/KPC-3

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
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