On the spine of a PDE surface

yesThe spine of an object is an entity that can characterise the object¿s topology and describes the object by a lower dimension. It has an intuitive appeal for supporting geometric modelling operations. The aim of this paper is to show how a spine for a PDE surface can be generated. For the purpose of the work presented here an analytic solution form for the chosen PDE is utilised. It is shown that the spine of the PDE surface is then computed as a by-product of this analytic solution. This paper also discusses how the of a PDE surface can be used to manipulate the shape. The solution technique adopted here caters for periodic surfaces with general boundary conditions allowing the possibility of the spine based shape manipulation for a wide variety of free-form PDE surface shapes

A survey of partial differential equations in geometric design

YesComputer aided geometric design is an area where the improvement of surface generation techniques is an everlasting demand since faster and more accurate geometric models are required. Traditional methods for generating surfaces were initially mainly based upon interpolation algorithms. Recently, partial differential equations (PDE) were introduced as a valuable tool for geometric modelling since they offer a number of features from which these areas can benefit. This work summarises the uses given to PDE surfaces as a surface generation technique togethe

Orientation and solvatochromism of dyes in liquid crystals.

The orientation and solvatochromism of some dye molecules in a liquid crystal have been investigated. Interactions with the host and the structure of the dye molecule affect the macroscopic alignment of dichroic dye molecules in a liquid crystal: It was observed that some dye molecules show a large bathochromic shift of their absorption maxima in the liquid crystal host relative to the situation in isotropic solvents. It is suggested that this is due to the occurrence of a much weaker reaction field in the anisotropic, rigid host. These dye molecules show little or no apparent order in the anisotropic host despite the observation of a reduction in the electro optic switching time when the dye is present. The highest degree of macroscopic alignment was observed for a merocyanine compound, which showed the smallest solvatochromic shift in the liquid crystal host. These results are discussed in terms of the steric, dipolar and hydrogen bond interactions between the guest and the host

A numerical study of a binary Yukawa model in regimes characteristic of globular proteins in solutions

The main goal of this paper is to assess the limits of validity, in the regime of low concentration and strong Coulomb coupling (high molecular charges), for a simple perturbative approximation to the radial distribution functions (RDF), based upon a low-density expansion of the potential of mean force and proposed to describe protein-protein interactions in a recent Small-Angle-Scattering (SAS) experimental study. A highly simplified Yukawa (screened Coulomb) model of monomers and dimers of a charged globular protein ($\beta$-lactoglobulin) in solution is considered. We test the accuracy of the RDF approximation, as a necessary complementary part of the previous experimental investigation, by comparison with the fluid structure predicted by approximate integral equations and exact Monte Carlo (MC) simulations. In the MC calculations, an Ewald construction for Yukawa potentials has been used to take into account the long-range part of the interactions in the weakly screened cases. Our results confirm that the perturbative first-order approximation is valid for this system even at strong Coulomb coupling, provided that the screening is not too weak (i.e., for Debye length smaller than monomer radius). A comparison of the MC results with integral equation calculations shows that both the hypernetted-chain (HNC) and the Percus-Yevick (PY) closures have a satisfactory behavior under these regimes, with the HNC being superior throughout. The relevance of our findings for interpreting SAS results is also discussed.Comment: Physical Review E, in press (2005

What young people want from health-related online resources: a focus group study

The growth of the Internet as an information source about health, particularly amongst young people, is well established. The aim of this study was to explore young people's perceptions and experiences of engaging with health-related online content, particularly through social media websites. Between February and July 2011 nine focus groups were facilitated across Scotland with young people aged between 14 and 18 years. Health-related user-generated content seems to be appreciated by young people as a useful, if not always trustworthy, source of accounts of other people's experiences. The reliability and quality of both user-generated content and official factual content about health appear to be concerns for young people, and they employ specialised strategies for negotiating both areas of the online environment. Young people's engagement with health online is a dynamic area for research. Their perceptions and experiences of health-related content seem based on their wider familiarity with the online environment and, as the online environment develops, so too do young people's strategies and conventions for accessing it

Mapping participation: a systematic analysis of diverse public participation in the UK energy system

This paper develops a novel approach to mapping diverse forms of participation and public engagement, using the example of the UK energy system. It builds on emerging systemic accounts of participation, which go beyond a focus on individual instances of participation, to gain an understanding of broader patterns and connections. Our approach, which forms part of an emerging family of methods that seek to map across multiple forms of public involvement in issues and systems, draws on systematic review methodology and a relational co-productionist conception of participation. The findings of a systematic mapping of public participation related to the UK energy system 2010–2015 are presented, comprising 258 cases in total. The mapping analysis reveals patterns as to the what (energy objects and issues), how (procedural formats) and who (publics) of energy participation in the UK, which go far beyond the conventionally assumed forms and sites of public participation around energy. Implications for how the dynamics of ‘whole system’ energy participation are represented and the role of approaches to mapping participation in governing energy transitions are considered

Sex differences in metabolic and adipose tissue responses to juvenile-onset obesity in sheep

Sex is a major factor determining adipose tissue distribution and the subsequent adverse effects of obesity-related disease including type 2 diabetes. The role of gender on juvenile obesity and the accompanying metabolic and inflammatory responses is not well established. Using an ovine model of juvenile onset obesity induced by reduced physical activity, we examined the effect of gender on metabolic, circulatory, and related inflammatory and energy-sensing profiles of the major adipose tissue depots. Despite a similar increase in fat mass with obesity between genders, males demonstrated a higher storage capacity of lipids within perirenal-abdominal adipocytes and exhibited raised insulin. In contrast, obese females became hypercortisolemic, a response that was positively correlated with central fat mass. Analysis of gene expression in perirenal-abdominal adipose tissue demonstrated the stimulation of inflammatory markers in males, but not females, with obesity. Obese females displayed increased expression of genes involved in the glucocorticoid axis and energy sensing in perirenal-abdominal, but not omental, adipose tissue, indicating a depot-specific mechanism that may be protective from the adverse effects of metabolic dysfunction and inflammation. In conclusion, young males are at a greater risk than females to the onset of comorbidities associated with juvenile-onset obesity. These sex-specific differences in cortisol and adipose tissue could explain the earlier onset of the metabolic-related diseases in males compared with females after obesity

Football in the community schemes: Exploring the effectiveness of an intervention in promoting healthful behaviour change

This study aims to examine the effectiveness of a Premier League football club’s Football in the Community (FitC) schemes intervention in promoting positive healthful behaviour change in children. Specifically, exploring the effectiveness of this intervention from the perspectives of the participants involved (i.e. the researcher, teachers, children and coaches). A range of data collection techniques were utilized including the principles of ethnography (i.e. immersion, engagement and observations), alongside conducting focus groups with the children. The results allude to the intervention merely ‘keeping active children active’ via (mostly) fun, football sessions. Results highlight the important contribution the ‘coach’ plays in the effectiveness of the intervention. Results relating to working practice (i.e. coaching practice and coach recruitment) are discussed and highlighted as areas to be addressed. FitC schemes appear to require a process of positive organizational change to increase their effectiveness in strategically attending to the health agenda

Elementary Forms of the Metaphorical Life : Tropes at Work in Durkheim’s Theory of the Religious

Peer reviewedPostprin