Naturalizing the Female Body: Social Control through Reproduction

Objective: To discuss alternatives to understand how the medical sciences have reduced the female body conceptually to its biological dimension as the foundation for its social control

Evolutionarily conserved mechanisms of male germline development in flowering plants and animals

Sexual reproduction is the main reproductive strategy of the overwhelming majority of eukaryotes. This suggests that the last eukaryotic common ancestor was able to reproduce sexually. Sexual reproduction reflects the ability to perform meiosis, and ultimately generating gametes, which are cells that carry recombined half sets of the parental genome and are able to fertilize. These functions have been allocated to a highly specialized cell lineage: the germline. Given its significant evolutionary conservation, it is to be expected that the germline programme shares common molecular bases across extremely divergent eukaryotic species. In the present review, we aim to identify the unifying principles of male germline establishment and development by comparing two very disparate kingdoms: plants and animals. We argue that male meiosis defines two temporally regulated gene expression programmes: the first is required for meiotic commitment, and the second is required for the acquisition of fertilizing ability. Small RNA pathways are a further key communality, ultimately ensuring the epigenetic stability of the information conveyed by the male germline

Estudio paleopatológico de la necrópolis mudéjar de la calle Colón, 3 (Novelda, Alicante)

X Congreso Nacional de Paleopatología. Univesidad Autónoma de Madrid, septiembre de 200

Identification of Globular Cluster Stars in RAVE data II: Extended tidal debris around NGC 3201

We report the identification of extended tidal debris potentially associated with the globular cluster NGC 3201, using the RAdial Velocity Experiment (RAVE) catalogue. We find the debris stars are located at a distance range of 1–7 kpc based on the forthcoming RAVE distance estimates. The derived space velocities and integrals of motion show interesting connections to NGC 3201, modulo uncertainties in the proper motions. Three stars, which are among the four most likely candidates for NGC 3201 tidal debris, are separated by 80° on the sky yet are well matched by the 12 Gyr, [Fe/H] = −1.5 isochrone appropriate for the cluster. This is the first time tidal debris around this cluster has been reported over such a large spatial extent, with implications for the cluster's origin and dynamical evolution

The hidden burden of adult allergic rhinitis : UK healthcare resource utilisation survey

Funding Funding for this survey was provided by Meda Pharma.Peer reviewedPublisher PD

Comparative Evaluation of Three Automated Systems for DNA Extraction in Conjunction with Three Commercially Available Real-Time PCR Assays for Quantitation of Plasma Cytomegalovirus DNAemia in Allogeneic Stem Cell Transplant Recipients▿

Limited data are available on the performance of different automated extraction platforms and commercially available quantitative real-time PCR (QRT-PCR) methods for the quantitation of cytomegalovirus (CMV) DNA in plasma. We compared the performance characteristics of the Abbott mSample preparation system DNA kit on the m24 SP instrument (Abbott), the High Pure viral nucleic acid kit on the COBAS AmpliPrep system (Roche), and the EZ1 Virus 2.0 kit on the BioRobot EZ1 extraction platform (Qiagen) coupled with the Abbott CMV PCR kit, the LightCycler CMV Quant kit (Roche), and the Q-CMV complete kit (Nanogen), for both plasma specimens from allogeneic stem cell transplant (Allo-SCT) recipients (n = 42) and the OptiQuant CMV DNA panel (AcroMetrix). The EZ1 system displayed the highest extraction efficiency over a wide range of CMV plasma DNA loads, followed by the m24 and the AmpliPrep methods. The Nanogen PCR assay yielded higher mean CMV plasma DNA values than the Abbott and the Roche PCR assays, regardless of the platform used for DNA extraction. Overall, the effects of the extraction method and the QRT-PCR used on CMV plasma DNA load measurements were less pronounced for specimens with high CMV DNA content (>10,000 copies/ml). The performance characteristics of the extraction methods and QRT-PCR assays evaluated herein for clinical samples were extensible at cell-based standards from AcroMetrix. In conclusion, different automated systems are not equally efficient for CMV DNA extraction from plasma specimens, and the plasma CMV DNA loads measured by commercially available QRT-PCRs can differ significantly. The above findings should be taken into consideration for the establishment of cutoff values for the initiation or cessation of preemptive antiviral therapies and for the interpretation of data from clinical studies in the Allo-SCT setting

Mapping the stellar population and gas excitation of MaNGA galaxies with MEGACUBES. Results for AGN versus control sample

We present spaxel-by-spaxel stellar population fits for the $\sim$10 thousand MaNGA datacubes. We provide multiple extension fits files, nominated as MEGACUBES, with maps of several properties as well as emission-line profiles that are provided for each spaxel. All the MEGACUBES are available through a web interface (https://manga.linea.org.br/ or http://www.if.ufrgs.br/~riffel/software/megacubes/). We also defined a final Active Galactic Nuclei (AGN) sample, as well as a control sample matching the AGN host galaxy properties. We have analysed the stellar populations and spatially resolved emission-line diagnostic diagrams of these AGNs and compared them with the control galaxies sample. We find that the relative fractions of young ($t \leq$56 Myr) and intermediate-age (100 Myr $\leq t \leq$ 2 Gyr) show predominantly a positive gradient for both AGNs and controls. The relative fraction of intermediate-age stellar population is higher in AGN hosts when compared to the control sample, and this difference becomes larger for higher [O III] luminosity AGNs. We attribute this to the fact that extra gas is available in these more luminous sources and that it most likely originates from mass-loss from the intermediate-age stars. The spatially resolved diagnostic diagrams reveal that the AGN emission is concentrated in the inner 0.5 $R_e$ (effective radius) region of the galaxies, showing that the AGN classification is aperture dependent and that emission-line ratios have to be taken together with the H$\alpha$ equivalent width for proper activity classification. We present a composite "BPT+WHAN" diagram that produces a more comprehensive mapping of the gas excitation.Comment: Accepted for publication in MNRA

Complementarity of Galactic radio and collider data in constraining WIMP dark matter models

In this work we confront dark matter models to constraints that may be derived from radio synchrotron radiation from the Galaxy, taking into account the astrophysical uncertainties and we compare these to bounds set by accelerator and complementary indirect dark matter searches. Specifically we apply our analysis to three popular particle physics models. First, a generic effective operator approach, in which case we set bounds on the corresponding mass scale, and then, two specific UV completions, the Z' and Higgs portals. We show that for many candidates, the radio synchrotron limits are competitive with the other searches, and could even give the strongest constraints (as of today) with some reasonable assumptions regarding the astrophysical uncertainties.Comment: 22 pages, 12 figure