Estructuración de una escuela de seguridad y salud en el trabajo basada en metodologías de aprendizaje activo, para reducir comportamientos inseguros en la Comercializadora Divantoque.

97 p.El presente trabajo propone el diseño de una escuela de Seguridad y Salud en el trabajo que permita fortalecer el programa de capacitaciones en promoción y prevención de los riesgos prioritarios identificados en la empresa Comercializadora Divantoque por medio de metodologías de aprendizaje activo . La estructura de la escuela está compuesta por 11 niveles que buscan que el personal adquiera conocimiento de una forma diferente e interactiva por medio de 4 metodologías seleccionadas en el desarrollo de la investigación . Inicialmente le permite al trabajador crear un avatar y un alias , con el cual participará en los niveles para obtener logros y puntuaciones que visualizará en un tablero gamificado seguido se usará microlearning para explicar el tema a exponer en cortos videos , aprendizaje experiencial para poner en práctica lo aprendido y por último repaso espaciado en diferentes lapsos para generar una mayor recordación de los temas estudiados. Para la ejecución de este trabajo se realizó una investigación de tipo descriptivo con una metodología cualitativa por medio de métodos etnográficos dado a que la información que se analizó cuenta elementos organizacionales como el perfil sociodemográfico y la batería psicosocial y un metodo analitico - deductivo conforme a la identificación de peligros y valoración de riesgos con el fin de mejorar los indicadores de Accidentes de trabajo y enfermedades laborales de toda la empresa obteniendo como resultado principal la importancia de conocer la realidad de la empresa y saber el tipo de personas que la conforman para poder aplicar capacitaciones idóneas y efectivas que generen impacto y cambios positivos en toda la organización.Resumen 8 Descripción de la problemática 9 Objetivos 11 Objetivo general 11 Objetivos específicos 11 Justificación 12 Delimitación de la investigación 13 Limitación de la investigación 13 Tiempo 13 Espacio 13 Recursos 13 Legal 14 Marcos de referencia 15 Estado del arte 15 Gamificación 15 Microlearning-Microaprendizaje 17 Mnemotécnica 18 Aprendizaje Experiencial 19 Tecnologías de la información y la comunicación TIC en el Proceso de aprendizaje 21 Repaso o Aprendizaje espaciado 24 Marco teórico 24 Seguridad y salud en el trabajo 25 Factores y riesgos psicosociales 25 Aprendizaje basado en juego 26 Gamificación 27 Microaprendizaje o Microlearning 31 Tecnologías de la información y la comunicación TIC en el Proceso de aprendizaje 33 Aprendizaje experiencial 34 Repaso espaciado 35 Promoción de estilos de vida saludable 36 Marco Legal 37 Decreto 1443 de 2014 37 Artículo y descripción de la normatividad 38 Evidencia de cumplimiento 38 Decreto 2404 del 2019 38 Artículo y descripción de la normatividad 38 Evidencia de cumplimiento 38 Resolución 0312 de 2019 39 Artículo aplicable y descripción de la normatividad 39 Evidencia de cumplimiento 39 Decreto 1072 de 2015 Capitulo 6 39 Artículo aplicable y descripción de la normatividad 40 Evidencia de cumplimiento 40 Guía Técnica Colombiana 45 40 Artículo aplicable y descripción de la normatividad 41 Evidencia de cumplimiento 41 Marco metodológico de la investigación 42 Paradigma 42 Método 42 Tipo de investigación 43 Fases del estudio 43 Fase 1 43 Descripción: 43 Meta: 43 Actividades: 43 Fase 2 44 Descripción: 44 Meta: 44 Actividades: 44 Fase 3 44 Descripción: 44 Meta: 44 Actividades: 44 Recolección de la información 45 Fuentes 45 Fuentes Primarias 45 Fuentes secundarias 45 Fuentes terciarias 45 Población 45 Muestra 45 Técnicas 46 Materiales 46 Procedimientos de la investigación 46 Procedimiento para establecer dinámica de aprendizaje 46 Identificación de peligros, valoración y evaluación de riesgos 48 Elaboración del plan de formación 50 Análisis de la información 52 Metodologías de aprendizaje 52 Gestión del riesgo 53 Cuadro de mando integral de riesgo 53 Informe del perfil sociodemográfico 58 Resumen de peligros identificados 63 Registro fotográfico 65 Informe Bateria de riesgo psicosocial 70 Cronograma de actividades 73 Resultados 74 Resultados objetivo 1 74 Repaso espaciado 74 Microlearning 75 Aprendizaje experiencial 75 Gamificación 75 Resultados objetivo 2 78 Resultados objetivo 3 82 Análisis costo beneficio 86 Discusión 89 Conclusiones 90 Recomendaciones 92 Referencias 93EspecializaciónEspecialización en Gerencia de la Seguridad y Salud en el trabaj

Nickel and cobalt ilmenites-based catalysts for upgrading pyrolytic oil during pyrolysis ofwaste tires

Pyrolysis as a waste treatment method has gained relevance because it can generate higher value-added products in addition to reducing the environment’s secondary pollution. In this study, the catalytic pyrolysis of waste tires was evaluated using NiTiO3 and CoTiO3 ilmenites as catalysts and precursors of metal catalysts with the aim to produce an oil enriched in high-value hydrocarbons, such as benzene, toluene, a xylenes mixture, and products less-reported, such as p-cymene and p-cymenene. The experiments were performed in an analytical pyrolyzer coupled to GC/MS. The effect of the nature of the catalysts on the product distribution was compared with the uncatalyzed reaction. The main products of uncatalyzed pyrolysis were D, L-limonene (~60%), and isoprene (~25%) due to the depolymerization of natural rubber. Meanwhile, Ni-ilmenites-based catalysts favored the formation of target compounds to expense D, L-limonene. Moreover, the presence of metal in reduced-ilmenite sharply enhanced the selectivity by ~50% concerning oxidized ilmenite and above 80% compared to the uncatalyzed reaction for p-cymene and p-cymenene. By contrast, the Co-ilmenites-based catalysts showed a marginal effect on secondary reactions. Finally, the feasibility of forming the aromatic terpenes, p-cymene, and p-cymenene from limonene in the non-catalytic pyrolysis was evaluated.Centro de Investigación y Desarrollo en Ciencias Aplicada

Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD

The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high-fat diet (HFD)-induced obesity and NAFLD in mice by enhancing liver fatty acid oxidation (FAO). Moreover, we searched for potential new lipid biomarkers for monitoring liver steatosis in humans. We used adeno-associated virus (AAV) to deliver a permanently active mutant form of human carnitine palmitoyltransferase 1A (hCPT1AM), the key enzyme in FAO, in the liver of a mouse model of HFD-induced obesity and NAFLD. Expression of hCPT1AM enhanced hepatic FAO and autophagy, reduced liver steatosis, and improved glucose homeostasis. Lipidomic analysis in mice and humans before and after therapeutic interventions, such as hepatic AAV9-hCPT1AM administration and RYGB surgery, respectively, led to the identification of specific triacylglyceride (TAG) specie (C50:1) as a potential biomarker to monitor NAFFLD disease. To sum up, here we show for the first time that liver hCPT1AM gene therapy in a mouse model of established obesity, diabetes, and NAFLD can reduce HFD-induced derangements. Moreover, our study highlights TAG (C50:1) as a potential noninvasive biomarker that might be useful to monitor NAFLD in mice and humans

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

The reanalysis of existing GWAS data represents a powerful and cost-effective opportunity to gain insights into the genetics of complex diseases. By reanalyzing publicly available type 2 diabetes (T2D) genome-wide association studies (GWAS) data for 70,127 subjects, we identify seven novel associated regions, five driven by common variants (LYPLAL1, NEUROG3, CAMKK2, ABO, and GIP genes), one by a low-frequency (EHMT2), and one driven by a rare variant in chromosome Xq23, rs146662057, associated with a twofold increased risk for T2D in males. rs146662057 is located within an active enhancer associated with the expression of Angiotensin II Receptor type 2 gene (AGTR2), a modulator of insulin sensitivity, and exhibits allelic specific activity in muscle cells. Beyond providing insights into the genetics and pathophysiology of T2D, these results also underscore the value of reanalyzing publicly available data using novel genetic resources and analytical approaches

The Eighteenth Data Release of the Sloan Digital Sky Surveys: Targeting and First Spectra from SDSS-V

The eighteenth data release of the Sloan Digital Sky Surveys (SDSS) is the first one for SDSS-V, the fifth generation of the survey. SDSS-V comprises three primary scientific programs, or "Mappers": Milky Way Mapper (MWM), Black Hole Mapper (BHM), and Local Volume Mapper (LVM). This data release contains extensive targeting information for the two multi-object spectroscopy programs (MWM and BHM), including input catalogs and selection functions for their numerous scientific objectives. We describe the production of the targeting databases and their calibration- and scientifically-focused components. DR18 also includes ~25,000 new SDSS spectra and supplemental information for X-ray sources identified by eROSITA in its eFEDS field. We present updates to some of the SDSS software pipelines and preview changes anticipated for DR19. We also describe three value-added catalogs (VACs) based on SDSS-IV data that have been published since DR17, and one VAC based on the SDSS-V data in the eFEDS field.Comment: Accepted to ApJ

The eighteenth data release of the Sloan Digital Sky Surveys : targeting and first spectra from SDSS-V

The eighteenth data release of the Sloan Digital Sky Surveys (SDSS) is the first one for SDSS-V, the fifth generation of the survey. SDSS-V comprises three primary scientific programs, or "Mappers": Milky Way Mapper (MWM), Black Hole Mapper (BHM), and Local Volume Mapper (LVM). This data release contains extensive targeting information for the two multi-object spectroscopy programs (MWM and BHM), including input catalogs and selection functions for their numerous scientific objectives. We describe the production of the targeting databases and their calibration- and scientifically-focused components. DR18 also includes ~25,000 new SDSS spectra and supplemental information for X-ray sources identified by eROSITA in its eFEDS field. We present updates to some of the SDSS software pipelines and preview changes anticipated for DR19. We also describe three value-added catalogs (VACs) based on SDSS-IV data that have been published since DR17, and one VAC based on the SDSS-V data in the eFEDS field.Publisher PDFPeer reviewe

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Guía de saúde infantil : actividades preventivas e de promoción da saúde en pediatría de atención primaria

Se trata de una guía de salud infantil dirigida a los profesionales que trabajan en el ámbito de la asistencia sanitaria a los niños y adolescentes en atención primaria del Sistema Público de Salud de Galicia.Trátase dunha guía de saúde infantil dirixida aos profesionais que traballan no ámbito da asistencia sanitaria aos nenos e adolescentes na atención primaria do Sistema Público de Saúde de Galicia

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac