5,384 research outputs found
Integrating Two Epistemological Goals: Why Shouldnât We Give It Another Chance?
As Beller, Bender, and Medin (in press) pointed out in their target article, in the contemporary study of culture in psychology, anthropology is virtually invisible. In this commentary, I traced this invisibility to a root conflict in epistemological goals of the two disciplines: Whereas anthropologists value rich description of specific cultures, psychologists aspire to achieve theoretical simplicity. To anthropologists, then, to understand culture is to articulate symbolic systems that are at work in a given location at a given time. In contrast, to psychologists, to understand culture amounts to identifying socioâcultural variables that moderate psychological effects. These divergent epistemological goals dictate both theoretical perspectives and empirical approaches in both disciplines. Yet, the two goals are both valid and in fact complementary. A renewed effort toward integration of the two goals may enrich both disciplines.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/92388/1/j.1756-8765.2012.01201.x.pd
Heavy-Baryon Spectroscopy from Lattice QCD
We use a four-dimensional lattice calculation of the full-QCD (quantum
chromodynamics, the non-abliean gauge theory of the strong interactions of
quarks and gluons) path integrals needed to determine the masses of the charmed
and bottom baryons. In the charm sector, our results are in good agreement with
experiment within our systematics, except for the spin-1/2 , for
which we found the isospin-averaged mass to be to be
MeV. We predict the mass of the (isospin-averaged)
spin-1/2 to be {MeV}. In the bottom
sector, our results are also in agreement with experimental observations and
other lattice calculations within our statistical and systematic errors. In
particular, we find the mass of the to be consistent with the recent
CDF measurement. We also predict the mass for the as yet unobserved
to be 5955(27) MeV.Comment: Invited talk at Conference of Computational Physics 2009. 3 page
General non-Markovian dynamics of open quantum systems
We present a general theory of non-Markovian dynamics for open quantum
systems. We explore the non-Markovian dynamics by connecting the exact master
equations with the non-equilibirum Green functions. Environmental back-actions
are fully taken into account. The non-Markovian dynamics consists of
non-exponential decays and dissipationless oscillations. Non-exponential decays
are induced by the discontinuity in the imaginary part of the self-energy
corrections. Dissipationless oscillations arise from band gaps or the finite
band structure of spectral densities. The exact analytic solutions for various
non-Markovian environments show that the non-Markovian dynamics can be largely
understood from the environmental-modified spectra of the open systems.Comment: 6 pages, 2 figure
Difficult birth is the main contributor to birthârelated fracture and accidents to other neonatal fractures
Aim Specific birth-related fractures have been studied; underestimates might be a problem. We aimed to assess all fractures diagnosed as birth-related as well as other neonatal fractures. Methods A population-based study on all infants born in Sweden 1997-2014; data were retrieved from the Swedish Health Registers (10th version of International Classification of Diseases. Outcome measures were birth-related fractures (ICD-10 P-codes) and other neonatal fractures (ICD-10 S-codes). Results The overall fracture incidence was 2.9 per 1000 live birth (N = 5336); 92.6% had P-codes and 7.4% (S-codes). Some birth-related fractures were diagnosed beyond the neonatal period. Other neonatal fractures could have been birth-related. Clavicle fracture (88.8%) was associated with adverse maternal and infant anthropometrics and birth complications. The few neonates with rib fractures all had concomitant clavicle fracture. For skull fractures, a minor part was birth-related and most were associated with accidents. Half of the long bone fractures were associated with accidents. Birth-related femur fractures were associated with bone fragility risk factors. Five infants with abuse diagnoses had fractures: skull (4), long bone (2) and rib (1). Conclusion Birth-related and other neonatal fractures are rarely diagnosed. Difficult birth is the main contributor to birth-related fracture and accidents to other neonatal fractures.Peer reviewe
IL-17A induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells
The epithelium plays an active role in the response to inhaled pathogens in part by responding to signals from the immune system. Epithelial responses may include changes in chemokine expression, increased mucin production and antimicrobial peptide secretion, and changes in ion transport. We previously demonstrated that interleukin-17A (IL-17A), which is critical for lung host defense against extracellular bacteria, significantly raised airway surface pH in vitro, a finding that is common to a number of inflammatory diseases. Using microarray analysis of normal human bronchial epithelial (HBE) cells treated with IL-17A, we identified the electroneutral chloride-bicarbonate exchanger Pendrin (SLC26A4) as a potential mediator of this effect. These data were verified by real-time, quantitative PCR that demonstrated a time-dependent increase in Pendrin mRNA expression in HBE cells treated with IL-17A up to 48 h. Using immunoblotting and immunofluorescence, we confirmed that Pendrin protein expression is increased in IL-17 treated HBE cells and that it is primarily localized to the mucosal surface of the cells. Functional studies using live-cell fluorescence to measure intracellular pH demonstrated that IL-17A induced chloride-bicarbonate exchange in HBE cells that was not present in the absence of IL-17A. Furthermore, HBE cells treated with short interfering RNA against Pendrin showed substantially reduced chloride-bicarbonate exchange. These data suggest that Pendrin is part of IL-17A-dependent epithelial changes and that Pendrin may therefore be a therapeutic target in IL-17A-dependent lung disease. © 2014 Adams et al
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Elderly learners and Massive Open Online Courses: a review
Background: Massive open online courses (MOOCs) have become commonplace in the e-learning landscape. Thousands of elderly learners are participating in courses offered by various institutions on a multitude of platforms in many different languages. However, there is very little research into understanding elderly learners in MOOCs.
Objective: We aim to show that a considerable proportion of elderly learners are participating in MOOCs and that there is a lack of research in this area. We hope this assertion of the wide gap in research on elderly learners in MOOCs will pave the way for more research in this area.
Methods: Pre-course survey data for 10 University of Reading courses on the FutureLearn platform were analyzed to show the level of participation of elderly learners in MOOCs. Two MOOC aggregator sites (Class Central and MOOC List) were consulted to gather data on MOOC offerings that include topics relating to aging. In parallel, a selected set of MOOC platform catalogues, along with a recently published review on health and medicine-related MOOCs, were searched to find courses relating to aging. A systematic literature search was then employed to identify research articles on elderly learners in MOOCs.
Results: The 10 courses reviewed had a considerable proportion of elderly learners participating in them. For the over-66 age group, this varied from 0.5% (on the course âManaging peopleâ) to 16.3% (on the course âOur changing climateâ), while for the over-56 age group it ranged from 3.0% (on âA beginners guide to writing in Englishâ) to 39.5% (on âHeart healthâ). Only six MOOCs were found to include topics related to aging: three were on the Coursera platform, two on the FutureLearn platform, and one on the Open2Study platform. Just three scholarly articles relating to MOOCs and elderly learners were retrieved from the literature search.
Conclusions: This review presents evidence to suggest that elderly learners are already participating in MOOCs. Despite this, there has been very little research into their engagement with MOOCs. Similarly, there has been little research into exploiting the scope of MOOCs for delivering topics that would be of interest to elderly learners. We believe there is potential to use MOOCs as a way of tackling the issue of loneliness among older adults by engaging them as either resource personnel or learners
Rendezvous on a Line by Location-Aware Robots Despite the Presence of Byzantine Faults
A set of mobile robots is placed at points of an infinite line. The robots
are equipped with GPS devices and they may communicate their positions on the
line to a central authority. The collection contains an unknown subset of
"spies", i.e., byzantine robots, which are indistinguishable from the
non-faulty ones. The set of the non-faulty robots need to rendezvous in the
shortest possible time in order to perform some task, while the byzantine
robots may try to delay their rendezvous for as long as possible. The problem
facing a central authority is to determine trajectories for all robots so as to
minimize the time until the non-faulty robots have rendezvoused. The
trajectories must be determined without knowledge of which robots are faulty.
Our goal is to minimize the competitive ratio between the time required to
achieve the first rendezvous of the non-faulty robots and the time required for
such a rendezvous to occur under the assumption that the faulty robots are
known at the start. We provide a bounded competitive ratio algorithm, where the
central authority is informed only of the set of initial robot positions,
without knowing which ones or how many of them are faulty. When an upper bound
on the number of byzantine robots is known to the central authority, we provide
algorithms with better competitive ratios. In some instances we are able to
show these algorithms are optimal
Approaching Conformality with Ten Flavors
We present first results for lattice simulations, on a single volume, of the
low-lying spectrum of an SU(3) Yang-Mills gauge theory with ten light fermions
in the fundamental representation. Fits to the fermion mass dependence of
various observables are found to be globally consistent with the hypothesis
that this theory is within or just outside the strongly-coupled edge of the
conformal window, with mass anomalous dimension consistent with 1 over the
range of scales simulated. We stress that we cannot rule out the possibility of
spontaneous chiral-symmetry breaking at scales well below our infrared cutoff.
We discuss important systematic effects, including finite-volume corrections,
and consider directions for future improvement.Comment: 7 pages, 3 figures. Submitted to Physical Review Letters. v2:
corrected global fits. v3: corrected estimation of confidence interval
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