371 research outputs found
Metode Pemicuan dalam Upaya Meningkatkan Budaya Pemberantasan Sarang Nyamuk (PSN) pada Masyarakat
This study aims to produce a triggering method to improve the culture of eradicating mosquito nests (PSN) in the community. The method used is quantitative research with research and development (R&D) design. The research results show that the PSN Mobile Triggering education model, namely the field triggering model followed by Android-based triggering, was declared feasible after the validation stage with 100% health promotion experts, 94.55% IT experts, 92% educational technology experts, and 80 practitioners. % and 93.85% one-on-one trials, 95% small group trials, and 96% large group trials. The PSN Mobile Trigger product effectively increases household mosquitoes' knowledge, attitudes, and behavior by up to 100% in eradicating mosquito nests. In conclusion, the educational model is feasible and effective to use to increase the knowledge, attitudes, and behavior of Jumantik Rumah in destroying mosquito nests.
Keywords: Android Based Application; Dengue Hemorrhagic Fever; Trigger Education; Eradication of Mosquito Nests, Mosquito Breeding Site
The English Vocabulary Mastery of the Fifth Grade Students of SD N 1 Gemulung Pecangaan Jepara in Academic Year 2013/2014 Taught by using TPR-Storytelling
Teaching English in Elementary school is not easy but it is interesting since English is as foreign language beside the characteristic of young learners itself. There are four basic skills (listening, speaking, reading, and writing) in learning language. The four skill are supported by language component they are vocabulary, pronounciation and grammar. The writer choose vocabulary as language component to conduct the research. Vocabulary is one important aspect in learning a foreign language. With a limited vocabulary anyone will also has a limited understanding in term of speaking, reading, listening, and writing. It is true that it might be impossible to learn a language without mastering vocabulary. In this case, most of students have difficulties in mastering English vocabulary. In the teaching and learning process the teacher should choose the appropriate technique in order to creat learning English vocabulary.
The study is aimed to find out the significant difference between the English vocabulary mastery of the fifth grade students of SD N 1 GemulungPecangaanJepara in academic year 2013/2014 before and after being taught by using TPR-Storytelling.
To be able to find the significant difference between the English vocabulary mastery of the fifth grade students of SD N 1 GemulungPecangaanJepara in academic year 2013/2014 before and after being taught by using TPR-Storytelling, the writer conduct an experimental research which is in the area of quantitatif. The population of this research is the fifth grade students of SD N 1 Gemulung Pecangaan Jepara which are consist of twenty eight students. Since the total population is less that one hundred so all of them takes as the subject of the research. Test is used as the instrument of the reseach. The the test is written test, the form of the test is multiple choise test that consist of twenty item test.
Based on the analyzing the data, it was found that the English vocabulary mastery of the fifth grade students of SD N 1 GemulungPecangaanJepara in academic year 2013/2014 after being taught by using TPR-Storytelling was categorized excellent. The mean is 87.46, and the standard deviation is 7.88. Meanwhile the English vocabulary mastery of the fifth grade students of SD N 1 GemulungPecangaanJepara in academic year 2013/2014 before being taught by using TPR-Storytelling was categorized sufficient. The mean is 65.5 and standard deviation is 15.85. Moreover the calculation of t-observation (to) 9.75 was higher than t-table (tt) 2.06 in level of significance 5%. It means there is significance difference between the English vocabulary mastery of the fifth grade students of SD N 1 GemulungPecangaanJepara in academic year 2013/2014 before and after being taught by using TPR-Storytelling
Based on the result above, the writer suggests that the English teacher is expected to use TPR-Storytelling as an alternative technique to teach English vocabulary mastery.The other researcher are suggested to conduct a study of this technique to the other English skill or the other subject in different level
PENERAPAN HYGIENE DAN SANITASI DI PONDOK PESANTREN AS’AD SEBERANG KOTA JAMBI TAHUN 2016
Various diseases based environment that is often a problem in General "as scabies, diarrhea, RESPIRATORY, caused by a less healthy environments in boarding schools ("). This research aims to gain an overview of the application of the Hygiene Sanitary boarding schools Usa, ad in the town of Jambi. The method of this research uses descriptive design answered the question question about who, what, when, where and how the interconnectedness with particular research. Data analysis analyzes the data Union variat and presented in tabular form then analyzed are descriptive. This research makes a picture about the State of Hygiene and sanitation of U.s. boarding schools, ad opposite the city of Jambi. The research results obtained that the application of Hygiene and sanitation in the US boarding schools, ad is still low and the students Knowledge about Hygiene and sanitation at boarding schools. It is suggested the necessity of understanding the material about basic sanitation to students and Personnel needed to improve sanitation sanitation conditions in boarding schools across the city of Jambi As'adKey words: boarding schools, Hygiene and sanitatio
Angka Kuman Pada Alat Makan di Kantin SDN No.47 Telanaipura Kota Jambi
Common environmental-based diseases are often a problem of diarrhea, ARI, and hepatitis caused by an unhealthy environment, including in the canteen environment of the 47 Telanaipura Jambi Primary School. This study aims to determine the Germ Number in eating utensils and how to wash eating utensils in the cafeteria of SDN 47 Telanaipura, Jambi City. This research method uses descriptive design, namely research carried out to describe a situation without giving treatment to the object that aims to study canteen sanitation and the number of germs on eating utensils in the cafeteria SDN No. 47 Jambi City. Analyzing data uni variat and presented in table form then analyzed descriptively and laboratory tests. The results of the research on Germination Figures in Eating Appliances in the SDN 47 Canteen obtained 40% more than the permissible germination rate of 100 colonies / cm² and Washing of food in SDN 47 Telanaipura Jambi had used the recommended washing technique using flowing water. It is suggested that the canteen sword does not use plastic plates, paying attention to the means of storing cutlery and the school is expected to facilitate the provision of closed storage cabinets
Pengaruh Faktor Iklim, Kepadatan Penduduk Dan Angka Bebas Jentik (Abj) Terhadap Kejadian Demam Berdarah Dengue (Dbd) Di Kota Jambi
Penyakit demam berdarah dengue (DBD) merupakan salah satu masalah kesehatan masyarakat di Indonesia yang disebabkan oleh lingkungan, jumlah penderitanya cenderung meningkat dan penyebarannya semakin luas. Kejadian DBD dipengaruhi oleh berbagai faktor, salah satunya dipengaruhi oleh cuaca/iklim. Secara geografis Indonesia termasuk beriklim tropis yang terbagi menjadi beberapa wilayah ekologi yang spesifik, yang merupakan tempat yang cocok untuk perkembangbiakan vektor, terutama vektor Aedes aegypti. Tujuan penelitian ini adalah memetakan kejadian DBD di Kota Jambi, menganalisis pengaruh iklim (temperatur, kelembaban dan curah hujan), terhadap kejadian DBD di Kota Jambi Menganalisis pengaruh kepadatan penduduk, Menganalisis pengaruh ABJ terhadap kejadian DBD di Kota Jambi.Penelitian ini merupakan penelitian studi ekologi atau studi korelasi populasi tentang faktor iklim (temperatur, kelembaban dan curah hujan) dengan kejadian DBD di Kota Jambi dalam 5 tahun (2010-2014), dianalisis secara pemetaan, grafik dan regresi. Hasil penelitian diperoleh bahwa temperatur yang tinggi tidak mempengaruhi tingginya kejadian DBD di Kota Jambi, Kelembaban berpengaruh terhadap kejadian DBD, dimana semakin rendah kelembaban maka kejadian DBD semakin tinggi, Curah hujan berpengaruh terhadap kejadian DBD, dimana semakin tinggi curah hujan maka kejadian DBD semakin tinggi, Kepadatan penduduk berpengaruh terhadap kejadian DBD, semakin tinggi kepadatan penduduk maka semakin tinggi kejadian DBD, ABJ tidak berpengaruh terhadap kejadian DBD, rendahnya ABJ tidak mempengaruhi tingginya kejadian DB
PENGARUH MODEL PEMBELAJARAN DISCOVERY LEARNING BERBASIS MIND MAPPING TERHADAP HASIL BELAJAR SISWA
Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran discovery learning berbasis mind mapping terhadap hasil belajar siswa. Penelitian dilakukan di SMP PGRI 06 Malang. Populasi penelitian adalah seluruh siswa kelas VIII. Sampel dipilih menggunakan teknik purposive sampling, kelas VIII A sebagai kelas eksperimen dan kelas VIII C sebagai kelas kontrol. Jenis penelitian yang digunakan yaitu quasi eksperiment dengan desain “posttest only control group design”. Teknik analisis data yang digunakan yaitu uji MANOVA. Hasil analisis data yang diperoleh yaitu: (1) ada perbedaan hasil belajar ranah afektif antara siswa yang belajar menggunakan model pembelajaran discovery learning berbasis mind mapping dengan siswa yang belajar menggunakan model pembelajaran konvensional, (2) ada perbedaan hasil belajar ranah psikomotor antara siswa yang belajar menggunakan model pembelajaran discovery learning berbasis mind mapping dengan siswa yang belajar menggunakan model pembelajaran konvensional, (3) ada perbedaan hasil belajar ranah kognitif antara siswa yang belajar menggunakan model pembelajaran discovery learning berbasis mind mapping dengan siswa yang belajar menggunakan model pembelajaran konvensional, (4) ada interaksi antara model pembelajaran discovery learning berbasis mind mapping terhadap hasil belajar siswa. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat pengaruh model pembelajaran discovery learning berbasis mind mapping terhadap hasil belajar siswa.
 
Islet Gene View-a tool to facilitate islet research
Characterization of gene expression in pancreatic islets and its alteration in type 2 diabetes (T2D) are vital in understanding islet function and T2D pathogenesis. We leveraged RNA sequencing and genome-wide genotyping in islets from 188 donors to create the Islet Gene View (IGW) platform to make this information easily accessible to the scientific community. Expression data were related to islet phenotypes, diabetes status, other islet-expressed genes, islet hormone-encoding genes and for expression in insulin target tissues. The IGW web application produces output graphs for a particular gene of interest. In IGW, 284 differentially expressed genes (DEGs) were identified in T2D donor islets compared with controls. Forty percent of DEGs showed cell-type enrichment and a large proportion significantly co-expressed with islet hormone-encoding genes; glucagon (GCG, 56%), amylin (IAPP, 52%), insulin (INS, 44%), and somatostatin (SST, 24%). Inhibition of two DEGs, UNC5D and SERPINE2, impaired glucose-stimulated insulin secretion and impacted cell survival in a human beta-cell model. The exploratory use of IGW could help designing more comprehensive functional follow-up studies and serve to identify therapeutic targets in T2D.Peer reviewe
Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells
Transplantation of pancreatic islet cells derived from human pluripotent stem cells is a promising treatment for diabetes. Despite progress in the generation of stem-cell-derived islets (SC-islets), no detailed characterization of their functional properties has been conducted. Here, we generated functionally mature SC-islets using an optimized protocol and benchmarked them comprehensively against primary adult islets. Biphasic glucose-stimulated insulin secretion developed during in vitro maturation, associated with cytoarchitectural reorganization and the increasing presence of alpha cells. Electrophysiology, signaling and exocytosis of SC-islets were similar to those of adult islets. Glucose-responsive insulin secretion was achieved despite differences in glycolytic and mitochondrial glucose metabolism. Single-cell transcriptomics of SC-islets in vitro and throughout 6 months of engraftment in mice revealed a continuous maturation trajectory culminating in a transcriptional landscape closely resembling that of primary islets. Our thorough evaluation of SC-islet maturation highlights their advanced degree of functionality and supports their use in further efforts to understand and combat diabetes. Pancreatic islets derived from stem cells are benchmarked against primary cells.Peer reviewe
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Comprehensive molecular characterization of gastric adenocarcinoma
Gastric cancer is a leading cause of cancer deaths, but analysis of its molecular and clinical characteristics has been complicated by histological and aetiological heterogeneity. Here we describe a comprehensive molecular evaluation of 295 primary gastric adenocarcinomas as part of The Cancer Genome Atlas (TCGA) project. We propose a molecular classification dividing gastric cancer into four subtypes: tumours positive for Epstein–Barr virus, which display recurrent PIK3CA mutations, extreme DNA hypermethylation, and amplification of JAK2, CD274 (also known as PD-L1) and PDCD1LG2 (also knownasPD-L2); microsatellite unstable tumours, which show elevated mutation rates, including mutations of genes encoding targetable oncogenic signalling proteins; genomically stable tumours, which are enriched for the diffuse histological variant and mutations of RHOA or fusions involving RHO-family GTPase-activating proteins; and tumours with chromosomal instability, which show marked aneuploidy and focal amplification of receptor tyrosine kinases. Identification of these subtypes provides a roadmap for patient stratification and trials of targeted therapies
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