About this Issue

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Publish or Perish: Can Scholarship and Teaching Coexist?

Faculty at institutions of higher education are experiencing constant requests to increase teaching loads and class sizes while, at the same time, continuing to meet the demands for scholarship and service. The Scholarship of Teaching and Learning (SoTL) can serve as one way in which faculty can simultaneously focus on improving their teaching and their students’ learning as well as meeting the rigorous demands for peer review and publication. The systematic approach of asking questions about one’s teaching, designing and conducting appropriate research methodologies to investigate those questions, analyzing the results, and subjecting the entire process and findings to peer review elevates good teaching to appropriate scholarship worthy of recognition in the tenure and promotion processes of higher education. This essay examines definitions and the history of the Scholarship of Teaching and Learning. In addition, it focuses on how faculty members can find time for and get started with SoTL work

Bringing the Ivory Tower and Real World Together: Lessons Learned in the Collaborative Process of Preparing Effective Teachers

When the “ivory tower” world of educator preparation faculty collides with the “real world” of in-service teachers, the result can be a partnership that is committed to preparing teachers equipped to meet the needs of diverse learners in 21st century classrooms. The lessons learned in the development of such a partnership include a focus on: a) authentic engagement of all stakeholders; b) honest, diplomatic, and timely communication; c) support and scaffolding for pre-service teachers; d) a variety of authentic assessment measures; and e) assistance for new teachers during the induction period. Strengthening the bonds between university faculty and classroom teachers has contributed to the success of pre-service and beginning teachers and to the enhancement of P-12 student learning

The Australasian Resuscitation In Sepsis Evaluation : fluids or vasopressors in emergency department sepsis (ARISE FLUIDS), a multi-centre observational study describing current practice in Australia and New Zealand

Objectives: To describe haemodynamic resuscitation practices in ED patients with suspected sepsis and hypotension. Methods: This was a prospective, multicentre, observational study conducted in 70 hospitals in Australia and New Zealand between September 2018 and January 2019. Consecutive adults presenting to the ED during a 30-day period at each site, with suspected sepsis and hypotension (systolic blood pressure <100 mmHg) despite at least 1000 mL fluid resuscitation, were eligible. Data included baseline demographics, clinical and laboratory variables and intravenous fluid volume administered, vasopressor administration at baseline and 6- and 24-h post-enrolment, time to antimicrobial administration, intensive care admission, organ support and in-hospital mortality. Results: A total of 4477 patients were screened and 591 were included with a mean (standard deviation) age of 62 (19) years, Acute Physiology and Chronic Health Evaluation II score 15.2 (6.6) and a median (interquartile range) systolic blood pressure of 94 mmHg (87–100). Median time to first intravenous antimicrobials was 77 min (42–148). A vasopressor infusion was commenced within 24 h in 177 (30.2%) patients, with noradrenaline the most frequently used (n = 138, 78%). A median of 2000 mL (1500–3000) of intravenous fluids was administered prior to commencing vasopressors. The total volume of fluid administered from pre-enrolment to 24 h was 4200 mL (3000–5661), with a range from 1000 to 12 200 mL. Two hundred and eighteen patients (37.1%) were admitted to an intensive care unit. Overall in-hospital mortality was 6.2% (95% confidence interval 4.4–8.5%). Conclusion: Current resuscitation practice in patients with sepsis and hypotension varies widely and occupies the spectrum between a restricted volume/earlier vasopressor and liberal fluid/later vasopressor strategy

Supported molybdenum carbide for higher alcohol synthesis from syngas

Molybdenum carbide supported on active carbon, carbon nanotubes, and titanium dioxide, and promoted by K2CO3, has been prepared and tested for methanol and higher alcohol synthesis from syngas. At optimal conditions, the activity and selectivity to alcohols (methanol and higher alcohols) over supported molybdenum carbide are significantly higher compared to the bulk carbide. The CO conversion reaches a maximum, when about 20 wt% Mo2C is loaded on active carbon. The selectivity to higher alcohols increases with increasing Mo2C loading on active carbon and reaches a maximum over bulk molybdenum carbide, while the selectivity to methanol follows the opposite trend. The effect of Mo2C loading on the alcohol selectivity at a fixed K/Mo molar ratio of 0.14 could be related to the amount of K2CO3 actually on the active Mo2C phase and the size, structure and composition of the supported carbide clusters. Unpromoted, active carbon supported Mo2C exhibits a high activity for CO conversion with hydrocarbons as the dominant products. The K 2CO3 promoter plays an essential role in directing the selectivity to alcohols rather than to hydrocarbons. The optimum selectivity toward higher alcohols and total alcohols is obtained at a K/Mo molar ratio of 0.21 over the active carbon supported Mo2C (20 wt%)

The examination of a teacher candidate assessment rubric: A confirmatory factor analysis

© 2016 Elsevier Ltd. This article examines the review and revision process of the Model of Appropriate Practice (MAP), a locally developed pre-service teacher candidate assessment rubric based on Danielson\u27s Framework for Teaching. The purpose was to confirm the quality of the rubric. As such, factor analysis was used to examine internal consistency and construct validity. The analysis yielded a 16-item rubric that showed strong estimates of reliability and validity across four teaching domains-planning and preparation, the classroom environment, instruction, and professional responsibilities. The importance of this process for improving teaching and teacher preparation is discussed

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors

Reactive carbonyl compounds (RCCs) formed during lipid peroxidation and sugar glycoxidation, namely Advanced lipid peroxidation end products (ALEs) and Advanced Glycation end products (AGEs), accumulate with ageing and oxidative stress-related diseases, such as atherosclerosis, diabetes or neurodegenerative diseases. RCCs induce the ‘carbonyl stress' characterized by the formation of adducts and cross-links on proteins, which progressively leads to impaired protein function and damages in all tissues, and pathological consequences including cell dysfunction, inflammatory response and apoptosis. The prevention of carbonyl stress involves the use of free radical scavengers and antioxidants that prevent the generation of lipid peroxidation products, but are inefficient on pre-formed RCCs. Conversely, carbonyl scavengers prevent carbonyl stress by inhibiting the formation of protein cross-links. While a large variety of AGE inhibitors has been developed, only few carbonyl scavengers have been tested on ALE-mediated effects. This review summarizes the signalling properties of ALEs and ALE-precursors, their role in the pathogenesis of oxidative stress-associated diseases, and the different agents efficient in neutralizing ALEs effects in vitro and in vivo. The generation of drugs sharing both antioxidant and carbonyl scavenger properties represents a new therapeutic challenge in the treatment of carbonyl stress-associated diseases