363 research outputs found

    AC losses in HTS coils for high-frequency and non-sinusoidal currents

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    AC losses in racetrack coils that are wound of YBCO tapes are measured for sinusoidal and non-sinusoidal transport currents with fundamental frequencies up to 1 kHz. An electrical method to measure losses for non-sinusoidal currents is developed for this purpose. The measured losses are compared to the losses calculated by 2D finite element models with power-law material models. The frequency and waveform-dependency of the measured losses are shown and compared to the results of the models over a wide range of frequencies and waveforms. Finally, it is shown that the finite element models can accurately predict AC losses resulting from non-sinusoidal transport currents as are present in highly dynamic motors with AC armature coils

    Alendroninezuur effectiever dan alfacalcidol voor preventie van osteoporose bij patiënten met een reumatische ziekte die starten met glucocorticoïdtherapie

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    OBJECTIVE: To compare the effects of alendronate and alfacalcidol in the prevention ofglucocorticoid-related osteoporosis in patients with a rheumatic disease. DESIGN: Randomised, double-blind, double-placebo clinical trial (www. clinicaltrials.gov; number: NCT00138983). METHODS: A total of 201 patients with rheumatic disease who were starting glucocorticoid treatment at a daily dose that was equivalent to at least 7.5 mg of prednisone were randomised to alendronate (10 mg) and a placebo capsule ofalfacalcidol daily (n = 100) or alfacalcidol (1 microg) and a placebo tablet ofalendronate daily (n = 101) for 18 months. Primary outcome was change in lumbar spine bone mineral density at 18 months. The main secondary outcome was the incidence of morphometrically confirmed vertebral deformities. RESULTS: Overall, 163 patients completed the study. The bone mineral density of the lumbar spine increased by 2.1% (95% CI: 1.1-3.1) in the alendronate group and decreased by 1.9% (95% CI: -3.I--0.7) in the alfacalcidol group. At 18 months the mean difference in change in bone mineral density between the two groups was 4.0% (95% CI: 2.4-5-5). Three patients in the alendronate group had a new vertebral deformity, compared with 8 patients in the alfacalcidol group, including 5 symptomatic vertebral fractures in 3 patients; the hazard ratio was 0.4 (95% CI: 0.1-1.4). CONCLUSION: Alendronate was more effective than alfacalcidol in preventing glucocorticoid-induced bone loss during this 18-month trial in patients with rheumatic diseases who were starting glucocorticoid treatment

    A microscopic approach to the response of 3^{\bf 3}He -4^{\bf 4}He mixtures

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    Correlated Basis Function perturbation theory is used to evaluate the zero temperature response S(q,ω)S(q,\omega) of 3^3He-4^4He mixtures for inelastic neutron scattering, at momentum transfers qq ranging from 1.11.1 to 1.7A˚11.7 \AA^{-1}. We adopt a Jastrow correlated ground state and a basis of correlated particle-hole and phonon states. We insert correlated one particle-one hole and one-phonon states to compute the second order response. The decay of the one-phonon states into two-phonon states is accounted for in boson-boson approximation. The full response is splitted into three partial components Sαβ(q,ω)S_{\alpha \beta}(q,\omega), each of them showing a particle-hole bump and a one phonon, delta shaped peak, which stays separated from the multiphonon background. The cross term S34(q,ω)S_{34}(q,\omega) results to be of comparable importance to S33(q,ω)S_{33}(q,\omega) in the particle-hole sector and to S44(q,ω)S_{44}(q,\omega) in the phonon one. Once the one-phonon peak has been convoluted with the experimental broadening, the computed scattering function is in semiquantitative agreement with recent experimental measurements.Comment: 26 pages, RevTex 3.0, 8 figures available upon reques

    Looking forward through the past: identification of 50 priority research questions in palaeoecology

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    1. Priority question exercises are becoming an increasingly common tool to frame future agendas in conservation and ecological science. They are an effective way to identify research foci that advance the field and that also have high policy and conservation relevance. 2. To date, there has been no coherent synthesis of key questions and priority research areas for palaeoecology, which combines biological, geochemical and molecular techniques in order to reconstruct past ecological and environmental systems on time-scales from decades to millions of years. 3. We adapted a well-established methodology to identify 50 priority research questions in palaeoecology. Using a set of criteria designed to identify realistic and achievable research goals, we selected questions from a pool submitted by the international palaeoecology research community and relevant policy practitioners. 4. The integration of online participation, both before and during the workshop, increased international engagement in question selection. 5. The questions selected are structured around six themes: human–environment interactions in the Anthropocene; biodiversity, conservation and novel ecosystems; biodiversity over long time-scales; ecosystem processes and biogeochemical cycling; comparing, combining and synthesizing information from multiple records; and new developments in palaeoecology. 6. Future opportunities in palaeoecology are related to improved incorporation of uncertainty into reconstructions, an enhanced understanding of ecological and evolutionary dynamics and processes and the continued application of long-term data for better-informed landscape management
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