115 research outputs found

    CARACTERÍSTICAS DE CARCAÇAS E VÍSCERAS DE FRANGOS DE CORTE ALIMENTADOS COM DIETAS COM ENZIMA BETA MANANASE E SOJA INTEGRAL DESATIVADA

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    This study aimed to evaluate the carcass characteristics and gastrointestinal biometry of broiler chickens fed with ration containing deactivated soybean supplemented with levels of beta mannanase enzyme. For this purpose, 1152 broilers from different lots of COOB 500 lineage were used. They were distributed in a completely randomized design in a 4x2 factorial scheme, with four levels of beta mannanase enzyme (0, 80, 160, 240g/ton) and inclusion or not of deactivated soybean, with eight replicates with 18 birds in each experimental unit. On the 42nd day, carcass, cuts, and viscera yield, in weight and percentage, and the gastrointestinal biometry of broiler chickens were evaluated. The post-fast weight, full carcass, empty carcass, breast, thigh, and drumstick had higher weight (p<0.05) for the treatment with the inclusion of deactivated soy. However, there was no difference (p>0.05) in the yield of edible viscera. In addition, there was an increase (p<0.05) in the gastrointestinal tract of birds as the enzyme beta mannanase was added. Thus, the use of deactivated soybean combined with the supplementation of 240 mg of beta mannanase enzyme in broiler chicken diets from 1 to 42 days of age is indicated, as it favors carcass yield and the morphology of the gastrointestinal tract of the birds. Keywords: Enzymes, supplementation, carcass yield, digestive tractO objetivo deste trabalho foi avaliar as características de carcaça e a biometria gastrointestinal de frangos de corte alimentados com ração contendo soja desativada suplementada com níveis de enzima Beta mananase. Para tal, foram utilizados 1152 frangos de corte de lotes diferentes da linhagem COOB 500. Estes foram distribuídos em um delineamento inteiramente casualizado em esquema fatorial 4x2, com quatro níveis de enzima Beta mananase (0, 80, 160, 240g/ton) e inclusão ou não de soja desativada, com oito repetições, sendo 18 aves em cada unidade experimental. No 42° dia, foram avaliados o rendimento de carcaça, cortes e vísceras, em peso e em porcentagem, e a biometria gastrointestinal dos frangos de corte. O peso pós-jejum, a carcaça cheia, a carcaça vazia, o peito, a coxa e a sobrecoxa tiveram maior peso (p<0,05) para o tratamento com a inclusão de soja desativada. No entanto, não houve diferença (p>0,05) para o rendimento de vísceras comestíveis. Além disso, houve um aumento (p<0,05) do trato gastrointestinal das aves, conforme a adição da enzima Beta mananase. Desta forma, indica-se, a utilização de soja desativada aliada à suplementação de 240 mg de enzima de Beta mananase em dietas de frangos de corte de um a 42 dias de idade, pois favorece o rendimento de carcaça e a morfologia do trato gastrointestinal das aves

    Orientações para Realização de Exames de Ressonância Magnética Nuclear em Pacientes com Dispositivos Eletrônicos Cardíacos

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    Estima-se que até 75% dos pacientes com dispositivos cardíacos eletrônicos implantáveis (DCEIs) terão indicação de exame de ressonância nuclear magnética (RNM) ao longo da vida. Pelas características dos dispositivos, esses foram excluídos historicamente do rol de pacientes considerados elegíveis ao exame

    Pervasive gaps in Amazonian ecological research

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    Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

    Pervasive gaps in Amazonian ecological research

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    Mitochondrial physiology

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    As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

    Mitochondrial physiology

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    As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

    Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

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    Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe
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