Manual for Operation of Mini Secchi Disc and the Mobile App TurbAqua Developed as Part of Revival Project

The Secchi disc measures transparency of water bodies in a fast, easy and precise way. The Secchi disc is a white disc that is lowered into the water and the depth at which this disc disappears from sight is logged as Secchi depth in the App. Transparency is the depth at which disc reappears, i.e., or how deep the sunlight can penetrate into a lake. The mini Secchi disc is basically a manually-operated tape measure with a white Secchi 10 cm disk and a brass weight of 100g attached to the tape end. The weight is manufactured using a metal lathe and the disc is made of white polypropylene sheet. The measuring tape is approximately 8m long wrapped around a 3D printed bobbin. For the easy handling of the device a polypropylene finger strap and nylon lanyard are attached to the casing. For prediction of colour of the water body, a vinyl-laminated Forel Ule colour scale sticker (with colour ranging from Indigo blue to Cola brown) is placed on the outside of the casing and the entire device is held together using stainless steel or brass fixings. In addition to this, an i-Button housed in a Thermochron water proof capsule ((DS9107) is attached to one of the weights, designed for measuring the water temperature

The long-term prediction of return to work following serious accidental injuries: A follow up study

Background Considerable indirect costs are incurred by time taken off work following accidental injuries. The aim of this study was to predict return to work following serious accidental injuries. Method 121 severely injured patients were included in the study. Complete follow-up data were available for 85 patients. Two weeks post trauma (T1), patients rated their appraisal of the injury severity and their ability to cope with the injury and its job-related consequences. Time off work was assessed at one (T2) and three years (T3) post accident. The main outcome was the number of days of sick leave taken due to the accidental injury. Results The patients' appraisals a) of the injury severity and b) of their coping abilities regarding the accidental injury and its job-related consequences were significant predictors of the number of sick-leave days taken. Injury severity (ISS), type of accident, age and gender did not contribute significantly to the prediction. Conclusions Return to work in the long term is best predicted by the patients' own appraisal of both their injury severity and the ability to cope with the accidental injury

Health status in the ambulance services: a systematic review

BACKGROUND: Researchers have become increasingly aware that ambulance personnel may be at risk of developing work-related health problems. This article systematically explores the literature on health problems and work-related and individual health predictors in the ambulance services. METHODS: We identified the relevant empirical literature by searching several electronic databases including Medline, EMBASE, PsychINFO, CINAHL, and ISI Web of Science. Other relevant sources were identified through reference lists and other relevant studies known by the research group. RESULTS: Forty-nine studies are included in this review. Our analysis shows that ambulance workers have a higher standardized mortality rate, higher level of fatal accidents, higher level of accident injuries and a higher standardized early retirement on medical grounds than the general working population and workers in other health occupations. Ambulance workers also seem to have more musculoskeletal problems than the general population. These conclusions are preliminary at present because each is based on a single study. More studies have addressed mental health problems. The prevalence of post-traumatic stress symptom caseness was > 20% in five of seven studies, and similarly high prevalence rates were reported for anxiety and general psychopathology in four of five studies. However, it is unclear whether ambulance personnel suffer from more mental health problems than the general working population. CONCLUSION: Several indicators suggest that workers in the ambulance services experience more health problems than the general working population and workers in other health occupations. Several methodological challenges, such as small sample sizes, non-representative samples, and lack of comparisons with normative data limit the interpretation of many studies. More coordinated research and replication are needed to compare data across studies. We discuss some strategies for future research

Acoustic Assessment of a Konjac–Carrageenan Tissue-Mimicking Material at 5–60 MHz

AbstractThe acoustic properties of a robust tissue-mimicking material based on konjac–carrageenan at ultrasound frequencies in the range 5–60 MHz are described. Acoustic properties were characterized using two methods: a broadband reflection substitution technique using a commercially available preclinical ultrasound scanner (Vevo 770, FUJIFILM VisualSonics, Toronto, ON, Canada), and a dedicated high-frequency ultrasound facility developed at the National Physical Laboratory (NPL, Teddington, UK), which employed a broadband through-transmission substitution technique. The mean speed of sound across the measured frequencies was found to be 1551.7 ± 12.7 and 1547.7 ± 3.3 m s−1, respectively. The attenuation exhibited a non-linear dependence on frequency, f (MHz), in the form of a polynomial function: 0.009787f2 + 0.2671f and 0.01024f2 + 0.3639f, respectively. The characterization of this tissue-mimicking material will provide reference data for designing phantoms for preclinical systems, which may, in certain applications such as flow phantoms, require a physically more robust tissue-mimicking material than is currently available

A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy

BACKGROUND Bleeding in early pregnancy is strongly associated with pregnancy loss. Progesterone is essential for the maintenance of pregnancy. Several small trials have suggested that progesterone therapy may improve pregnancy outcomes in women who have bleeding in early pregnancy. METHODS We conducted a multicenter, randomized, double-blind, placebo-controlled trial to evaluate progesterone, as compared with placebo, in women with vaginal bleeding in early pregnancy. Women were randomly assigned to receive vaginal suppositories containing either 400 mg of progesterone or matching placebo twice daily, from the time at which they presented with bleeding through 16 weeks of gestation. The primary outcome was the birth of a live-born baby after at least 34 weeks of gestation. The primary analysis was performed in all participants for whom data on the primary outcome were available. A sensitivity analysis of the primary outcome that included all the participants was performed with the use of multiple imputation to account for missing data. RESULTS A total of 4153 women, recruited at 48 hospitals in the United Kingdom, were randomly assigned to receive progesterone (2079 women) or placebo (2074 women). The percentage of women with available data for the primary outcome was 97% (4038 of 4153 women). The incidence of live births after at least 34 weeks of gestation was 75% (1513 of 2025 women) in the progesterone group and 72% (1459 of 2013 women) in the placebo group (relative rate, 1.03; 95% confidence interval [CI], 1.00 to 1.07; P=0.08). The sensitivity analysis, in which missing primary outcome data were imputed, resulted in a similar finding (relative rate, 1.03; 95% CI, 1.00 to 1.07; P=0.08). The incidence of adverse events did not differ significantly between the groups. CONCLUSIONS Among women with bleeding in early pregnancy, progesterone therapy administered during the first trimester did not result in a significantly higher incidence of live births than placebo. (Funded by the United Kingdom National Institute for Health Research Health Technology Assessment program; PRISM Current Controlled Trials number, ISRCTN14163439. opens in new tab.

DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia

No abstract available

Graded bandgap semiconductor thin film photoelectrodes

The differences among phytoplankton carbon (Cphy) predictions from six ocean color algorithms are investigated by comparison with in situ estimates of phytoplankton carbon. The common satellite data used as input for the algorithms is the Ocean Color Climate Change Initiative merged product. The matching in situ data are derived from flow cytometric cell counts and per-cell carbon estimates for different types of pico-phytoplankton. This combination of satellite and in situ data provides a relatively large matching dataset (N > 500), which is independent from most of the algorithms tested and spans almost two orders of magnitude in Cphy. Results show that not a single algorithm outperforms any of the other when using all matching data. Concentrating on the oligotrophic regions (Chlorophyll-a concentration, B, less than 0.15 mg Chl m−3), where flow cytometric analysis captures most of the phytoplankton biomass, reveals significant differences in algorithm performance. The bias ranges from −35 to +150% and unbiased root mean squared difference from 5 to 10 mg C m−3 among algorithms, with chlorophyll-based algorithms performing better than the rest. The backscattering-based algorithms produce different results at the clearest waters and these differences are discussed in terms of the different algorithms used for optical particle backscattering coefficient (bbp) retrieval