Insect avoidance may override human disturbances in reindeer habitat selection

Habitat selection of semi-domesticated reindeer (Rangifer tarandus tarandus) was investigated through faecal pellet- group counts and by direct observations of reindeer from helicopter in the Långfjället area in Idre reindeer herding district (62˚10’N) and in Mittådalen reindeer herding district (62˚50’N, aerial observations only). Reindeer pellets were found to be most abundant in habitats at high altitudes, and in some vegetation types. Pellet-group densities tended to be higher near the tourist trails, which often follow higher altitudes in the terrain. The aerial surveys showed that the reindeer moved towards higher altitudes when the wind speed was low and the temperature was high both in June and July. In June they moved towards lower regions when temperature was low and the wind speed was strong. The conclusion is that the reindeer use Långfjället to escape insect harassment and warm weather, even though disturbance by tourism sometimes is high.Abstract in Swedish / Sammanfattning:Habitatval hos tamren (Rangifer tarandus tarandus) undersöktes genom att göra en spillningsinventering och genom att göra flygobservationer från helikopter. Studien gjordes på Långfjället (62˚10’N) i Idre nya sameby och i Mittådalens samebys sommarbetesområde (62˚50’N, endast flygobservationer). På Långfjället finns det vandringsleder som är frekventerade av vandrare från juni månad fram till september. Spillningen visade att renarna föredrog höjderna i området samt en del av vegetationstyperna. Det var också mer spillning närmare vandringslederna. Detta kan förklaras av att vandringslederna följer höjderna i terrängen. Flyginventeringarna under både juni och juli visade att renarna rörde sig mot högre terräng när det var varmt och lugnt väder. I juni rörde dom sig också i lägre terräng när det var stark vind och kallt väder. Slutsatsen är att renarna väljer att vistas i högre terräng för att undvika störningar från insekter och för att finna svalka trots att det är mänsklig aktivitet i området

Blood-Brain Barrier Penetration of Zolmitriptan—Modelling of Positron Emission Tomography Data

Positron emissiontomography (PET) with the drug radiolabelled allows a direct measurement of brain or other organ kinetics, information which can be essential in drug development. Usually, however, a PET-tracer is administered intravenously (i.v.), whereas the therapeutic drug is mostly given orally or by a different route to the PET-tracer. In such cases, a recalculation is needed to make the PET data representative for the alternative administration route. To investigate the blood-brain barrier penetration of a drug (zolmitriptan) using dynamic PET and by PK modelling quantify the brain concentration of the drug after the nasal administration of a therapeutic dose. [11C]Zolmitriptan at tracer dose was administered as a short i.v. infusion and the brain tissue and venous blood kinetics of [11C]zolmitriptan was measured by PET in 7 healthy volunteers. One PET study was performed before and one 30min after the administration of 5mg zolmitriptan as nasal spray. At each of the instances, the brain radioactivity concentration after subtraction of the vascular component was determined up to 90min after administration and compared to venous plasma radioactivity concentration after correction for radiolabelled metabolites. Convolution methods were used to describe the relationship between arterial and venous tracer concentrations, respectively between brain and arterial tracer concentration. Finally, the impulse response functions derived from the PET studies were applied on plasma PK data to estimate the brain zolmitriptan concentration after a nasal administration of a therapeutic dose. The studies shows that the PET data on brain kinetics could well be described as the convolution of venous tracer kinetics with an impulse response including terms for arterial-to-venous plasma and arterial-to-brain impulse responses. Application of the PET derived impulse responses on the plasma PK from nasal administration demonstrated that brain PK of zolmitriptan increased with time, achieving about 0.5mg/ml at 30min and close to a maximum of 1.5mg/ml after 2hr. A significant brain concentration was observed already after 5min. The data support the notation of a rapid brain availability of zolmitriptan after nasal administratio

Impacts of moose (Alces alces) at different simulated densities on eco-morphological groups of soil mesofauna

We experimentally tested the impact of browsing, defecation and urination corresponding to four different levels of moose population density on abundance and number of eco-morphological groups of soil mesofauna in a Swedish boreal forest. The study was carried out in three fenced exclosures representing different levels of productivity (from nutrient-rich to nutrient-poor). Moose impact on soil communities was evaluated by analysing abundance, richness and diversity of mesofaunal groups, and by means of a multi-taxa index based on ecomorphological groups, the Biological Soil Quality index (QBS). There was a negative impact of high moose densities on the abundance and richness of soil mesofauna. Furthermore, low-moderate moose densities had a positive impact on abundance and number of eco-morphological groups. We conclude that moose can have a large impact on soil-living mesofauna, and therefore probably soil decomposition processes and biological soil quality, in young boreal forest stands

Food plots as a habitat management tool: forage production and ungulate browsing in adjacent forest

A key challenge for wildlife management is to handle competing goals. High ungulate densities may be desirable from hunting and recreational perspectives, but may come in conflict with needs to limit or reduce browsing damage. Since browsing intensity is negatively related to forage availability it may be possible to mitigate damage on forest by increasing forage availability within the landscape. A commonly used method to increase the attractiveness of a localized part of the landscape is to establish food plots. In a multiyear setup using enclosures, wildlife observations, field surveys, and controlled biomass removal, we studied food plots to document forage production, utilization by ungulates, and browsing on adjacent forests in southern Sweden. The fenced parts of the food plots produced on average 2230 to 5810 kg ha. 1 marrow-stem kale, second-year clover mix or early-sown rapeseed. The biomass of target crops was generally higher within ungrazed (exclosures) compared to grazed (controls) quadrats on the food plots, which demonstrates that the crops were used as forage by ungulates. Browsing on deciduous trees in the adjacent forest was higher within 70-135 m from the food plots compared to areas further away. For wildlife management, our study shows that establishment of food plots provides substantial amounts of forage both during growing season and at the onset of the dormant season, and that a large share of this food is consumed. Finally, our study documents that forage availability for ungulates at the onset of the often-limiting dormant season can be increased by fencing food plots throughout the growing season

Kunskap om Vilt och Skog 4

• Klövviltet är en förnybar resurs som har såväl ekologiska, ekonomiska som sociala värden. • Samtidigt orsakar klövviltets bete på träd nedsatt virkeskvalitet, minskad tillväxt och därmed minskat ekonomiskt utbyte för skogsnäringen. • En ökad fodermängd i landskapet kan minska betestrycket på ekonomiskt viktiga trädslag. • Genom att anlägga viltåkrar kan fodertillgången i landskapet ökas och viss del av betningen styras mot dessa. • Studien visar att 1 700–13 000 kg foder (torrvikt) per hektar potentiellt kan skapas beroende på gröda, men att en stor del konsumeras av klövviltet redan på sommaren. • I brynen kring viltåkrarna var betestrycket på lövträd 20–50 % högre än på marker längre från åkrarna, vilket tyder på en ökad skaderisk för träd i direkt anslutning till åkrarna

Of goats and spines : a feeding experiment

This is the postprint version of the article.Spines in plants have evolved to reduce mammalian herbivory, and their main function may be to protect twigs more than photosynthetic tissue. Type and frequency of spines vary in different scales. We hypothesised that different types of spines affect animal foraging through different mechanisms. We studied feeding behaviour by twig browsing goats in relation to two types of spines of Acacia tortilis using experimental manipulation of the occurrence of spines. Feeding time, number of biting actions, number and diameter of bites on trees (post-trial) and total intake were recorded. The removal of either long straight spines or short hooked spines resulted in no feeding responses by goats. The removal of both types of spines tended to increase feeding time resulting in more and larger bites with larger bite diameters and in increased total intake and utilisation compared to control branches. The removal of spines gave no effects on feeding rate, expressed as biting actions/minute, number of twigs bitten/minute or intake rate (g/minute). Both types of spines reduced total intake and utilisation of browse, but the functional mechanisms were different with the long straight spines mainly influencing bite size and short hooked spines mainly affecting number of bites

A modern way to teach and practice manual therapy

Background: Musculoskeletal conditions are the leading contributor to global disability and health burden. Manual therapy (MT) interventions are commonly recommended in clinical guidelines and used in the management of musculoskeletal conditions. Traditional systems of manual therapy (TMT), including physiotherapy, osteopathy, chiropractic, and soft tissue therapy have been built on principles such as clinician-centred assessment, patho-anatomical reasoning, and technique specificity. These historical principles are not supported by current evidence. However, data from clinical trials support the clinical and cost effectiveness of manual therapy as an intervention for musculoskeletal conditions, when used as part of a package of care. Purpose: The purpose of this paper is to propose a modern evidence-guided framework for the teaching and practice of MT which avoids reference to and reliance on the outdated principles of TMT. This framework is based on three fundamental humanistic dimensions common in all aspects of healthcare: safety, comfort, and efficiency. These practical elements are contextualised by positive communication, a collaborative context, and person-centred care. The framework facilitates best-practice, reasoning, and communication and is exemplified here with two case studies. Methods: A literature review stimulated by a new method of teaching manual therapy, reflecting contemporary evidence, being trialled at a United Kingdom education institute. A group of experienced, internationally-based academics, clinicians, and researchers from across the spectrum of manual therapy was convened. Perspectives were elicited through reviews of contemporary literature and discussions in an iterative process. Public presentations were made to multidisciplinary groups and feedback was incorporated. Consensus was achieved through repeated discussion of relevant elements. Conclusions: Manual therapy interventions should include both passive and active, person-empowering interventions such as exercise, education, and lifestyle adaptations. These should be delivered in a contextualised healing environment with a well-developed person-practitioner therapeutic alliance. Teaching manual therapy should follow this model

Mechanisms of manipulation:a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation

Background: Spinal manipulation (SM) has been claimed to change anatomy, either in structure or position, and that these changes may be the cause of clinical improvements. The aim of this systematic review was to evaluate and synthesise the peer-reviewed literature on the current evidence of anatomical changes in response to SM. Methods: The review was registered with PROSPERO (CRD42022304971) and reporting was guided by the standards of the PRISMA Statement. We searched Medline, Embase, CINAHL, AMED, Cochrane Library all databases, PEDro, and the Index to Chiropractic Literature from inception to 11 March 2022 and updated on 06 June 2023. Search terms included manipulation, adjustment, chiropractic, osteopathy, spine and spine-related structures. We included primary research studies that compared outcomes with and without SM regardless of study design. Manipulation was defined as high-velocity, low-amplitude thrust delivered by hand to the spine or directly related joints. Included studies objectively measured a potential change in an anatomical structure or in position. We developed a novel list of methodological quality items in addition to a short, customized list of risk of bias (RoB) items. We used quality and RoB items together to determine whether an article was credible or not credible. We sought differences in outcomes between SM and control groups for randomised controlled trials and crossover studies, and between pre- and post-SM outcomes for other study designs. We reported, in narrative form, whether there was a change or not. Results: The search retrieved 19,572 articles and 20 of those were included for review. Study topics included vertebral position (n = 3) facet joint space (n = 5), spinal stiffness (n = 3), resting muscle thickness (n = 6), intervertebral disc pressure (n = 1), myofascial hysteresis (n = 1), and further damage to already damaged arteries (n = 1). Eight articles were considered credible. The credible articles indicated that lumbar facet joint space increased and spinal stiffness decreased but that the resting muscle thickness did not change. Conclusion: We found few studies on this topic. However, there are two promising areas for future study: facet joint space and spinal stiffness. A research strategy should be developed with funding for high quality research centres