264 research outputs found
Capacidades dinâmicas e turismo: uma análise bibliométrica
This article analyzes bibliometric networks into research on dynamic capabilities that are related to tourism, identifying emerging trends in the area and consolidated themes in this field of study. This study is a qualitative and exploratory meta-analysis of 384 scientific articles published between January 1995 and June 2021. We used meta-analysis due to using mapping and clustering techniques of bibliometric networks, with the Vosviewer software. The results present the central elements in the social networks of researchers and the topics related to the research on dynamic capabilities in tourism, as well as showing the formation of five main clusters representing five focuses on analysis: impacts and sustainability (cluster 1), clusters and absorptive capacity (cluster 2), strategic planning (cluster 3), technology and innovation (cluster 4), coopetition (cluster 5).O presente artigo objetiva analisar as redes bibliométricas sobre a pesquisa em capacidades dinâmicas que estão relacionadas ao turismo, identificando novas tendências que estão surgindo na área, bem como os temas que estão consolidados nesse campo de estudo. Trata-se de uma meta-análise qualitativa e exploratória que sistematiza a análise de 384 artigos científicos publicados entre janeiro de 1995 e junho de 2021. O uso da meta-análise se justifica pela utilização de técnicas de mapeamento e clusterização das redes bibliométricas, feitas a partir do software Vosviewer. Os resultados apresentam os elementos centrais nas redes sociais de pesquisadores e nos temas relacionados à pesquisa sobre capacidades dinâmicas no turismo, bem como evidenciam a formação de cinco clusters principais que representam cinco focos de análise: impactos e sustentabilidade (cluster 1); clusters e capacidade absortiva (cluster 2); planejamento estratégico (cluster 3); tecnologia e inovação (cluster 4); e coopetição (cluster 5).Este artículo tiene como objetivo analizar las redes bibliométricas de investigaciones sobre capacidades dinámicas que se relacionan con el turismo, las cuales identifican nuevas tendencias que están surgiendo en el área, así como temáticas que se consolidan en este campo de estudio. Este es un metaanálisis cualitativo y exploratorio que sistematiza el análisis de 384 artículos científicos publicados entre enero de 1995 y junio de 2021. El uso del metaanálisis se justifica por el uso de técnicas de mapeo y agrupación de redes bibliométricas en combinación con el apoyo del software Vosviewer. Los resultados presentan los elementos clave en las redes sociales de los investigadores y en los temas relacionados con la investigación sobre capacidades dinámicas en turismo, además de mostrar la formación de cinco clústeres principales que representan cinco focos de análisis: impactos y sostenibilidad (clúster 1), clústeres y capacidad de absorción (clúster 2), planificación estratégica (clúster 3), tecnología e innovación (clúster 4), coopetencia (clúster 5)
Elaboração de cerveja com mel de Apis mellifera L. florada Aroeira e raiz de gengibre (Zingiber officinale) e análise do teor de fenóis totais e atividade antioxidante / Beer elaboration with honey from Apis mellifera L. flowering Aroeira and ginger root (Zingiber officinale) and analysis of the total phenol content and antioxidant activity
A cerveja é uma das bebidas mais antigas do mundo. Sua origem está ligada ao surgimento da agricultura e principalmente da elaboração de pão. Obtida a partir da fermentação de mosto de cereais maltados (que podem ser substituídos parcialmente por adjuntos cervejeiros) e adicionada de lúpulo, a cerveja conta também com uma variedade de compostos bioativos, vitaminas e minerais capazes de trazer benefícios quando ingerida com moderação. Com o crescimento do mercado de cervejas artesanais a busca por sabores diferenciados e formulações únicas tem aumentado. O objetivo deste trabalho foi a produção de uma cerveja artesanal com mel de Apis mellifera L. florada aroeira e raiz de gengibre (Zingiber officinale), análise do teor de fenóis e da sua atividade antioxidante, sendo produzida e testada no Laboratório de Bioquímica e Biotecnologia da Universidade Estadual do Ceará (LABBIOTEC), a cerveja apresentou para a análise de fenóis totais 8,2±0,7 mg EAG/100g e uma atividade antioxidante de 56,49±0,39 (IC50) mg/ml, que comparados com os adjuntos utilizados na sua produção foi um resultado inferior, porém significativo, tornando a cerveja de mel de Apis mellifera L. florada aroeira e raiz de gengibre (Zingiber officinale) uma alternativa para o mercado cervejeiro
Padrão de distribuição das veias anastomóticas de Labbé e Trolard em função da lateralidade e sexo
INTRODUÇÃO: As veias anastomóticas superior (de Trolard) e inferior (de Labbé), responsáveis por comunicar a veia cerebral média aos seios sagital superior e transverso, respectivamente, tornam-se importantes na área da neurocirurgia, uma vez que são veias de alto risco para lesões nos procedimentos cirúrgicos por serem localizadas em topografias de acesso constante. Na literatura, são mostradas as consequências do acometimento dessas veias durante procedimentos cirúrgicos, o que inclui edema cerebral, infarto venoso e hemorragia, dentre outras intercorrências. OBJETIVO: Investigar o padrão de distribuição das veias anastomóticas de Labbé e Trolard em função da lateralidade e do sexo em exames de arteriografia cerebral. MÉTODOS: Este projeto foi desenvolvido na Faculdade de Medicina de Olinda. Trata-se de um estudo do tipo transversal, observacional e retrospectivo. Foram analisados 20 exames de angiografia como quantitativo inicial, tornando este trabalho um estudo piloto para análises com amostras mais significativas posteriormente. Foram incluídos exames de arteriografias com avaliação da drenagem venosa do cérebro e excluídos os exames de arteriografia cerebral que não possuam as três incidências utilizadas no exame. Para análise dos dados, foram utilizadas estatística descritiva, de acordo com cada objetivo proposto. RESULTADOS: A veia anastomótica de Labbé foi mais prevalente à direita no sexo feminino, enquanto à esquerda foi mais prevalente no sexo masculino. Já a veia anastomótica de Trolard foi mais prevalente à direita no sexo masculino, enquanto à esquerda foi mais prevalente no sexo feminino. CONCLUSÃO: O presente estudo descreveu o padrão de distribuição das veias anastomóticas de Labbé e Trolard em função da lateralidade e sexo relacionando os achados com potenciais complicações secundárias à lesão venosa iatrogênica, demonstrando a importância do conhecimento da anatomia destas estruturas vasculares e suas implicações cirúrgicas
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In
the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
El surgimiento de la perspectiva de la competitividad turística social: Mapeo y clusterización de Redes Bibliométricas
The objective of this study is to perform an analysis of bibliometric
networks of research on tourism competitiveness in order to identify new trends that are emerging in
this theme, as well as, which topics have already consolidated in that field. It is qualitative and
exploratory research that systematizes the analysis of 128 scientific papers published between 1999
and 2018. It can be classified as a qualitative meta-analysis because the study of bibliometric
networks combined mapping and clustering techniques performed by Vosviewer software. The results
analysis showed the elements of centrality in the social networks of researchers and the centrality of
themes related to tourism competitiveness. Also, findings showed the new frontier on this scientific
field, new clusters of researchers in the subject. Thus, results contribute to consolidate the boundaries
of studies on tourism destinations competitiveness focusing on the social. Based on the results, this
study offers a concept for social tourism competitiveness that emerges from the literature and can re-
conceptualize the theoretical economic assumptions that are still pillars of most monitors of tourism
competitiveness.El objetivo de este artículo es realizar un análisis de redes bibliométricas sobre la
investigación en competitividad turística de forma de identificar las nuevas tendencias que están
surgiendo en esta temática, así como los temas ya consolidados en este campo de estudio. Se trata
de una investigación cualitativa y exploratoria que sistematiza el análisis de 128 artículos científicos
publicados entre 1999 y 2018. Se puede clasificar como un meta-análisis cualitativo, pues para el
análisis de las redes bibliométricas se utilizaron las técnicas de mapeo y clusterización en forma
combinada mediante el software Vosviewer. El análisis mostró los elementos centrales en las redes
sociales de investigadores y en los temas relacionados con la investigación sobre competitividad
social. Además, muestra el surgimiento de tendencias en la investigación de este campo científico,
así como nuevos clusters de investigadores en el tema consolidando fronteras de estudio volcadas a
pensar la competitividad turística y de destinos haciendo foco en lo social. En base a los resultados,
este estudio ofrece un concepto para la competitividad turística social que surge de la literatura y
puede redefinir los presupuestos teóricos económicos que aún son pilares de la mayoría de los
monitores de la competitividad turística
Two decades of evolution in tourism competitiveness: a co-word analysis
Purpose The objective of this study was to analyze the evolution of tourism competitiveness over the years, ascertaining the state of the art and the degree of consensus among scholars on its constituent elements to propose an integrative and updated concept
Development and validation of the MMCD score to predict kidney replacement therapy in COVID-19 patients
Abstract Background Acute kidney injury (AKI) is frequently associated with COVID-19, and the need for kidney replacement therapy (KRT) is considered an indicator of disease severity. This study aimed to develop a prognostic score for predicting the need for KRT in hospitalised COVID-19 patients, and to assess the incidence of AKI and KRT requirement. Methods This study is part of a multicentre cohort, the Brazilian COVID-19 Registry. A total of 5212 adult COVID-19 patients were included between March/2020 and September/2020. Variable selection was performed using generalised additive models (GAM), and least absolute shrinkage and selection operator (LASSO) regression was used for score derivation. Accuracy was assessed using the area under the receiver operating characteristic curve (AUC-ROC). Results The median age of the model-derivation cohort was 59 (IQR 47–70) years, 54.5% were men, 34.3% required ICU admission, 20.9% evolved with AKI, 9.3% required KRT, and 15.1% died during hospitalisation. The temporal validation cohort had similar age, sex, ICU admission, AKI, required KRT distribution and in-hospital mortality. The geographic validation cohort had similar age and sex; however, this cohort had higher rates of ICU admission, AKI, need for KRT and in-hospital mortality. Four predictors of the need for KRT were identified using GAM: need for mechanical ventilation, male sex, higher creatinine at hospital presentation and diabetes. The MMCD score had excellent discrimination in derivation (AUROC 0.929, 95% CI 0.918–0.939) and validation (temporal AUROC 0.927, 95% CI 0.911–0.941; geographic AUROC 0.819, 95% CI 0.792–0.845) cohorts and good overall performance (Brier score: 0.057, 0.056 and 0.122, respectively). The score is implemented in a freely available online risk calculator ( https://www.mmcdscore.com/ ). Conclusions The use of the MMCD score to predict the need for KRT may assist healthcare workers in identifying hospitalised COVID-19 patients who may require more intensive monitoring, and can be useful for resource allocation
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