12 research outputs found
The Gulf and Southeast Asia: Regional Security Complex and Regional Security Community. A Comparative Study
- Publication venue
- Institute of Arab and Islamic Studies
- Publication date
- 21/03/2013
- Field of study
The study covers two regions. These are shown to constitute ‘Regional security complexes’. The Gulf region and the Gulf Cooperation Council (GCC) and the Association of Southeast Asian Nations (ASEAN) in the Southeast Asian region are the focus of study. The defence and security circumstances of the two regions and the responses of the regions’ governments severally and cooperatively are examined. The study has had to take account of the geographic, historical, ethno-cultural differences between the two regions. These are shown to be influential in their respective security responses. Nonetheless, the thesis demonstrates how the regions can be understood in terms of a common theoretical framework.
The study is undertaken primarily within the framework of the theory of ‘Regional Security Complex’ (RSCT), as developed by Buzan and Waever in Regions and Power. Regional security complexes are areas of internal “security interdependence” and securitisation. The theory (RSCT) is discussed critically. ‘Security Communities’ is a major comparative feature of the study. Amitav Acharya develops this approach in Constructing a Security Community in Southeast Asia. Emphasis is on the “creative construction” of a ‘security community’. The Gulf Cooperation Council may also be viewed in this way. ‘Regional security complex’ and ‘regional security community’ are not alternative theories of regional inter-state relations. The second is superstructural on the prior facts of regional security complexity. The GCC is a partial response to regional security and is a securitising actor in the region. ASEAN is an attempt at region-wide inclusiveness and conflict avoidance.
Institutional management of security is described. The two regional approaches differ as beliefs that the “enmity/amity balance” is amenable to official regional policy and action: the Gulf and GCC are apparently locked in a dominant ‘enmity’ scenario; ASEAN seeks to establish a regime of ‘amity’. Whether ASEAN is notably less militarily oriented than the Gulf is questioned. States’ insistence on national security ‘resilience’ and ASEAN norms of ‘sovereignty’, ‘non-interference’ and conflict avoidance’ impede regional security development. ASEAN’s progress towards an ‘ASEAN Security Community’ is examined.
The study discusses practicalities of these policies. The application and limitations of ‘Revolution in military affairs’ (RMA) are discussed. The military are viewed as a principal operational actor in any regional security response to conditions of regional security complexity. An examination of state-military relations is based on the concepts of ‘grand strategy’ and ‘military doctrine’
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub M.
- A. Adam M.
- A. Nassar M.
- A. Nemer A.
- Aahlin E. K.
- Ab Rahim M. F.
- Abad Gurumeta A.
- Abad-Motos A.
- Abang Jamari D. Z. H.
- Abantanga F.
- Abarca S.
- Abazid E.
- Abbas A.
- Abbas K.
- Abbas M. M.
- Abbasy J.
- Abbosh A.
- Abd B.
- Abd Karim M. F. S.
- Abd Wahab H. H.
- Abdalei A.
- Abdalla Ahmed Elkamel A.
- Abdallah A.
- AbdAllah M. S. M.
- Abdel Malik A. B.
- Abdelhady Mousa H.
- Abdelhady S.
- Abdelhakim A.
- Abdelkader M.
- Abdelkawy S.
- Abdelkhalek M.
- Abdellatif E.
- Abdelmaksoud Tawakel N.
- Abdelmohsen N.
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- Abdelsalam I.
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- Zupan D.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
The Gulf and Southeast Asia : regional security complex and regional security community : a comparative study
- Publication venue
- Publication date
- 01/01/2012
- Field of study
The study covers two regions. These are shown to constitute ‘Regional security complexes’. The Gulf region and the Gulf Cooperation Council (GCC) and the Association of Southeast Asian Nations (ASEAN) in the Southeast Asian region are the focus of study. The defence and security circumstances of the two regions and the responses of the regions’ governments severally and cooperatively are examined. The study has had to take account of the geographic, historical, ethno-cultural differences between the two regions. These are shown to be influential in their respective security responses. Nonetheless, the thesis demonstrates how the regions can be understood in terms of a common theoretical framework. The study is undertaken primarily within the framework of the theory of ‘Regional Security Complex’ (RSCT), as developed by Buzan and Waever in Regions and Power. Regional security complexes are areas of internal “security interdependence” and securitisation. The theory (RSCT) is discussed critically. ‘Security Communities’ is a major comparative feature of the study. Amitav Acharya develops this approach in Constructing a Security Community in Southeast Asia. Emphasis is on the “creative construction” of a ‘security community’. The Gulf Cooperation Council may also be viewed in this way. ‘Regional security complex’ and ‘regional security community’ are not alternative theories of regional inter-state relations. The second is superstructural on the prior facts of regional security complexity. The GCC is a partial response to regional security and is a securitising actor in the region. ASEAN is an attempt at region-wide inclusiveness and conflict avoidance. Institutional management of security is described. The two regional approaches differ as beliefs that the “enmity/amity balance” is amenable to official regional policy and action: the Gulf and GCC are apparently locked in a dominant ‘enmity’ scenario; ASEAN seeks to establish a regime of ‘amity’. Whether ASEAN is notably less militarily oriented than the Gulf is questioned. States’ insistence on national security ‘resilience’ and ASEAN norms of ‘sovereignty’, ‘non-interference’ and conflict avoidance’ impede regional security development. ASEAN’s progress towards an ‘ASEAN Security Community’ is examined. The study discusses practicalities of these policies. The application and limitations of ‘Revolution in military affairs’ (RMA) are discussed. The military are viewed as a principal operational actor in any regional security response to conditions of regional security complexity. An examination of state-military relations is based on the concepts of ‘grand strategy’ and ‘military doctrine’.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
In Vitro Evaluation of the Inhibitory Activity of Thymoquinone in Combatting Candida albicans in Denture Stomatitis Prevention
- Publication venue
- 'MDPI AG'
- Publication date
- 01/07/2017
- Field of study
Candida albicans adhesion and proliferation on denture bases may lead to denture stomatitis, which is a common and recurrent problem in denture wearers. The goal of this study was to assess the inhibitory effect of thymoquinone incorporated in the polymethyl methacrylate denture base material against Candida albicans. Eighty acrylic resin specimens were fabricated and divided into eight groups (n = 10) according to thymoquinone concentrations of 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, and 5% of acrylic powder. Two methods were used to evaluate the effect of thymoquinone on Candida albicans: the slide count and the serial dilution test. A multivariate analysis of variance (MANOVA) and the post-hoc Tukey’s Honestly Significant Difference (HSD) test were performed to compare the difference of means between the observations taken at various intervals with baseline. The p value was statistically significant at ≤0.05. According to the slide count and the serial dilution test, the mean number of adhered Candida albicans in the control group was 5436.9 ± 266 and 4691.4 ± 176.8; however, this number dramatically decreased to 0 ± 0 and 32.4 ± 1.7 in group 8 (concentration 5%). These results suggest that the incorporation of thymoquinone into the acrylic resin denture base material might be effective in preventing Candida albicans adhesion
Based blockchain-PSO-AES techniques in finger vein biometrics: A novel verification secure framework for patient authentication
- Author
- A.A. Zaidan
- A.H. Mohsin
- A.S. Albahri
- Abdulnabi
- Abomhara
- Abomhara
- Ahmed
- Al-Ani
- Al-Bakri
- Al-Frajat
- Al-khateeb
- Alanazi
- Alanazi
- Alanazi
- Alanazi
- Alanazi
- Alanazi
- Albahri
- Albahri
- Albahri
- Albahri
- Albahri
- Alblooshi
- Ali
- Alsalem
- Alsalem
- Alshehhi
- B.B. Zaidan
- Chan
- Chavez-Galaviz
- Da Wu
- Elnajjar
- Elshoura
- Eltahir
- Enaizan
- Fernández-Caramés
- Hamdan
- Hamdan
- Hameed
- Hameed
- Hmood
- Hmood
- Hmood
- Hongbo
- Hussain
- Hussain
- Hussain
- Hussain
- Hussain
- Ibrahim
- Ioannidou
- Iqbal
- Jagadiswary
- Jain
- Jalab
- Jalab
- Jialiang Peng
- K.I. Mohammed
- Kalid
- Kalid
- Khalifa
- Kiah
- Kiah
- Kiah
- Kshetri
- Kundi
- Li
- Liu
- Lu
- Lu
- M.A. Alsalem
- Majeed
- Mat Kiah
- Mat Kiah
- Mathur
- Matos
- Medani
- Miura
- Mohsin
- Mohsin
- Mohsin
- Murakami
- N.Sugandhi
- Nabi
- Nabi
- Naji
- Naji
- Naji
- Naji
- Naji
- Naji
- Naji
- Naji
- Naji
- Nandhinipreetha
- Nassar
- Nidhal
- O.S. Albahri
- Ong
- Ordaz-Gutierrez
- Othman
- Park
- Peng
- Prasad
- Salah
- Salem
- Salman
- Sameer
- Shen
- Shihab
- Shuwandy
- Singh
- Skillen
- Suzuki
- Talal
- Talal
- Talib
- Tang
- Taqa
- Tariq
- Thamallah
- Tian
- Von Solms
- Watari
- William
- Wu
- Yahya
- Yang
- Yas
- Yun-peng
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Zaidan
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
- Abdelkareem Mohamed
- Abdelkarem Mohamed
- Abdelkarim Mostafa
- Abdelkhalek Mohamed
- Abdellah Fatima
- Abdelmajeed Ahmed
- Abdelmalik Abubaker
- Abdelmawla Ahmed
- Abdelrahman Abdelrahman
- Abdelrahman Haneen
- Abdelraouf Ali
- Abdelsamed Ahmed
- Abdelwahab Omar
- Abderrazaq Hafni
- Abdissa Desalegn
- Abdo Adnan Sayid
- Abdou Hossam
- Abdou Mostafa
- Abdoun Meriem
- Abdow Mohammad
- Abdrabou Ahmed
- Abdualqader Mahmmoud
- Abdul-Jabar Hani
- Abdul-Mumin Alhassan
- Abdulaal Safaa
- Abdulateef Omar
- Abdulfattah Ammar Yasser
- Abdulkareem Amal
- Abdull Mohammed
- Abdullaev Abakar
- Abdullah Abdullah
- Abdullah Bahiyah
- Abdullah Duha Milad
- Abdullah Muhammad Tariq
- Abdullah Nabila
- Abdullah Saleha
- Abdullah Shahbaz
- Abdullaha Lamess
- Abdullahi Alhassan
- Abdullahi Habiba
- Abdullahi Lawal
- Abdullahi Mohammed Kabir
- Abdullahi Sani
- Abdullahi Yasir Younis
- Abdulmalek Abdulmalek
- Abdulmalik Abdulmuez
- Abdulmohsen Ahmed
- Abdulqawi Nabil
- Abdulrahem Abdullah
- Abdulrahman Mamuda
- Abdulrahman Mohamed
- Abdulrahman Taha
- Abdulsalam Albaraa
- Abdulsalam Fareed
- Abdulsalam Khalifa
- Abdulsalam Moruf
- Abdulwahab Taiceer
- Abdulwahed Eman
- Abdunabi Murad
- Abdur-Rahman Lukman
- Abdurab Ebrahim
- Abdurehman Oumer
- Abdurrazzaaq Abdussemee
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abe Anthonia
- Abe Nobutsugu
- Abe Tatsuro
- Abebe Engida
- Abebe Kirubel
- Abebe Metasebia
- Abebe Nebyou
- Abebrese John Tabiri
- Abed Arsan Abu
- Abed Francisco
- Abed Haneen
- Abed Laith Abu
- Abedalqader Lina
- Abedin Yasmin
- Abel Joel Reuben
- Abel Livingston
- Abel Mary Kathryn
- Abelevich Alexander
- Abella Andrei Cesar
- Abichou Wijden
- Abid Rubaba
- Abiodun Adekunle
- Abiola Olajide
- Abiola Paul
- Abiyere Henry
- Aboalsamh Ghaleb
- Aboazamazem Hajir
- Abodeeb Aya
- Aboelkhel Roger
- Abojeila Farah
- Abosamak Nour Eldin
- Abosnaina Yahya
- Abostate Ahmed
- Abou-Abbass Hussein
- Abou-Khalil Jad
- Abouassi Layth
- Abouassi Majd
- Aboubakr Samar
- Aboubeirah Mohammed
- Abouelazayem Mohamed
- Abouelnagah Galal
- Abouelnagah Yossof
- Aboutaleb Shereen
- Aboutrab Ayham
- Abouzid Amr
- Abozied Hesham
- Abraham Bejoy
- Abrahams Jenevive
- Abramowicz Shelly
- Abrate Alberto
- Abreha Tassew
- Abrha Teklebirhan
- Abu-Arish Hamdoon
- Abu-Eisheh Basil
- Abu-Ishkerih Nizar
- Abu-Ismail Luai
- Abu-Libdeh Tareq
- Abu-Mehsen Marah
- Abu-Zaid Ahmed
- Abualteen Faisal
- Abuawad Carla
- Abubakar Abdullah
- Abubakar Ahmed
- Abubakar Mohammed Kabir
- Abubakr Abubakr
- Abubakr Asmaa
- Abubeih Hossam
- Abud Burçin
- Abudari Hadeel
- Abudher Abdulhafid
- Abuhamour Ehab
- Abuissa Khatab
- Abukhadra Mahmoud
- Abukhalaf Sadi A
- Abukhater Muhammad
- Abulafia Daniel
- Abuleil Amro
- Abulshuwashi Nayrouz Abdullah
- Abumahara Saleh
- Abunawas Huthifa
- Aburahmah Mohammad
- Aburayyan Fatima
- Aburima Sarah
- Abusabeib Abdelrahman
- Abusadah Samer
- Abusalem Marwa
- Abusannoga Malek
- Abushahma Ahmed Omar
- Abutaka Ahmad
- Abutaleb Malak
- Abuzaina Khalil
- Acatrinei Eduard
- Accarino Giulio
- Accorsi Guilherme
- Acharya Hriday
- Acharya Metesh
- Acharya Shivanie
- Achimas-Cadariu Patriciu
- Ackermann Travis
- Acosta Jesus
- Acosta Maria
- Acosta Yancy
- Acosta Úrsula
- Acquaye Jane
- Acra-Tolari Ricardo
- Acuña Gastón
- Adam John
- Adamala Soujanya
- Adamina Michel
- Adamoli Laura
- Adams Katie
- Adapa Akshath
- Addas Bassam
- Adebajo Emmanuel
- Adebanjo Ademola
- Adebara Idowu
- Adebayo Olaolu
- Adebayo Sikiru A
- Adeboyejo Oluwaseun
- Adegbola Samuel
- Adel Dina
- Adelaja Aderinsola
- Adeleye Amos
- Adeli Seyyed Hassan
- Adem Ephrem
- Ademola Samuel
- Ademuyiwa Adesoji
- Adeniran Abimbola
- Adeniran Abiodun
- Adeniyi Adebayo
- Adenwalla Mehjabeen
- Aderogba Adeleke Akeem
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Oluwaseyi
- Adesola Muideen
- Adeyemo Olabisi
- Adeyeye Ademola
- Adham Ibrahim
- Adi Hussam
- Adiamah Alfred
- Adikaibe Valentine
- Adil Md Tanveer
- Adisa Adewale
- Aditianingsih Dita
- Adjeso Theophilus
- Adlan Alsafe
- Adler Tina
- Admasu Azarias
- Adofo-Asamoah Yvonne
- Adrees Mohammed
- Adrianzén Marcos
- Adu-Aryee Nii Armah
- Aduse-Poku Maame
- Advani Rajeev
- Adze Joel
- Aeed Majed
- Afaque Syed Nayyar
- Afifi Amgad
- Afifi Eman
- Afifi Nermeen
- Afify Abdelrahman
- Afolabi Abdulrahman O
- Afolabi Akinwale
- Afolabi Bosede
- Afshar Salim
- Aftab Raiyyan
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Maimoona
- Afzal Mohamed
- Afzal Muhammad Farooq
- Afzal Sadia
- Agalianos Christos
- Agapov Mikhail
- Agarwal Anjoo
- Agarwal Arnav
- Agarwal Gaurav
- Agarwal Ketan
- Agarwal Sunny
- Agarwal Varun
- Agastra Ervis
- Agbadebo Mouhamed
- Agbaje Ademola
- Agbedinu Kwabena
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agboadoh Nelson
- Agbonrofo Peter
- Ageeli Mohammed
- Aggarwal Gaurav
- Aggarwal Manisha
- Aggarwal Sonali
- Aghababyan Kristina
- Aghadi Ifeanyi
- Aghalarov Ilgar
- Aghamaliyev Ughur
- Aghayeva Afag
- Aghazadeh Kayvan
- Agida Eyaofun
- Agnes Annamaria
- Agnes Salvatore
- Agoncillo Anika Johanna
- Agossou Hermann
- Agrawal Amit
- Agrawal Mansi
- Agrawal Rachit
- Agrawal Sanjit Kumar
- Agrawal Tulika
- Agro Felice Eugenio
- Aguado Héctor J
- Aguayo Omar
- Aguilar Ana
- Aguilar Ruben
- Aguilera-Arevalo Maria-Lorena
- Aguinagalde Borja
- Aguirre Asier
- Aguzzoli Lorenzo
- Agyapong Meshach Manu
- Agyei Fareeda
- Agyeman-Duah Nana Kwaku
- Agyemang-Prempeh Akosua
- Agyen Thomas
- Ahamed Waseem
- Ahangari Roghayyeh
- Aherne Thomas
- Ahlaou Hamza
- Ahluwalia Saravpreet
- Ahmad Afaf
- Ahmad Ahmad Mustafa
- Ahmad Aline
- Ahmad Amer
- Ahmad Ashfaq
- Ahmad Aya
- Ahmad Basel
- Ahmad Fateen
- Ahmad Jameel Ismail
- Ahmad Maleeha
- Ahmad Manzoor
- Ahmad Misbahu
- Ahmad Mohamad
- Ahmad Muzaffar Ahmad
- Ahmad Niarah
- Ahmad Qamar Ashfaq
- Ahmad Quazi
- Ahmad Reyaz
- Ahmad Rofida
- Ahmad Saad Bilal
- Ahmad Shabir
- Ahmad Shahrukh
- Ahmad Sheraz
- Ahmad Siddique
- Ahmad Tareq
- Ahmad Zeeshan
- Ahmadi Navid
- Ahmadi Sayedali
- Ahmadvand Ali
- Ahmed Abdelkareem
- Ahmed Abdullah
- Ahmed Abedelrahman
- Ahmed Ahme
- Ahmed Aishah
- Ahmed Aminat Olayinka
- Ahmed Arooj
- Ahmed Ayman
- Ahmed Azaz
- Ahmed Ehsan
- Ahmed Faazil
- Ahmed Faryal
- Ahmed Ghazia
- Ahmed Haseeb
- Ahmed Hassaan
- Ahmed Idrees
- Ahmed Iffat
- Ahmed Irshad
- Ahmed Islam
- Ahmed Jawad
- Ahmed Kaleem
- Ahmed Khalid
- Ahmed Maira
- Ahmed Malik Shakeel
- Ahmed Manhal
- Ahmed Mariam
- Ahmed Moaiad Eldin
- Ahmed Mohamme
- Ahmed Muhammed
- Ahmed Nasir
- Ahmed Nauman
- Ahmed Omar
- Ahmed Safia
- Ahmed Sara
- Ahmed Shahnoor
- Ahmed Shakil
- Ahmed Sheraz
- Ahmed Waheed-Ul-Rahman
- Ahmed Waqas
- Ahmed Zubair
- Ahmedin Mahlet
- Ahsan Kunwar Armash
- Ahseen Naeimah
- Ahtash Abdurahman
- Aidarov Askar
- Aigner Felix
- Aiken Taylor
- Ailabouni Ramez
- Aimé Adeline
- Aiolfi Alberto
- Airoldi Angelo
- Aisuodionoe-Shadrach Oseremen
- Aitken Jake
- Aizza Giada
- Ajab Shereen
- Ajagha Okeoghene
- Ajai Olalekan
- Ajaj Hatem
- Ajami Dany
- Ajao Akinlabi
- Ajayi Adekunle
- Ajayi Peter
- Ajcip Gaby
- Ajekwu Samuel
- Ajekwu Temitope
- Aji Narjiss
- Aji Sani Ali
- Ajibola Hafees
- Ajiboye Olalekan
- Ajlan Abdulrazag
- Ajmi Ghadeer Al
- Ajmi Khalil Al
- Ajomah Nadia
- Akaba Godwin
- Akadh Ali
- Akalin Murat
- Akani Chris
- Akanni Bolaji
- Akbar Ali
- Akbar Bilal
- Akbar Hazrat Akbar
- Akbari Amir Ali
- Akbas Ahmet
- Akdeniz Yesim
- Akeel Nouf
- Akgor Utku
- Akhavizadegan Hamed
- Akhbari Melika
- Akhtar Amina
- Akhtar Fahad
- Akhtar Muhammad Adeel
- Akhtar Muhammad Shaheer
- Akhtar Munazza
- Akhtar Naseem
- Akhtar Tasleem
- Akhund Ramsha
- Akiely Jehad
- Akililu Yemisirach Bizuneh
- Akin Emrah
- Akinajo Opeyemi
- Akindoyin Success
- Akinloa Olufemi
- Akinmade Akinola
- Akinsola Sanusi
- Akinyemi Tosin
- Akkour Khalid
- Akl Michel
- Aklilu Abenezer Tirsit
- Akmercan Ahmet
- Akpla Marcellin
- Akpoghor Oghenevwegba
- Akram Shahzad
- Aktaa Nazeeh Al
- Akthar Farah
- Aktimur Yunus Emre
- Akulaev Anton
- Akyol Cihangir
- Akça Oktay
- Akçay Mertcan
- Al Aggeliki
- Al Aya Abdul
- Al-Abri Rashid
- Al-Absi Emad
- Al-Adwan Sofian
- Al-Ameri Saba
- Al-Atiyah Hussam
- Al-Azzawi Marwa
- Al-Badawi Ismail
- Al-Balas Hasan
- Al-Dabaa Tawfik
- Al-Darabah Ali
- Al-Dhaheri Awsan
- Al-Dolat Wedad
- Al-Embideen Somya
- Al-Eryani Fatima
- Al-Garadi Abdulrahman Faisal
- Al-Gilani Maha
- Al-Habib Amro
- Al-Hasani Fahad
- Al-Hebbah Amer
- Al-Houssami Salma
- Al-Howthi Mohammed
- Al-Isawi Ali
- Al-Jadaan Mohammad
- Al-Jarrah Amar
- Al-Jarrah Hothaifa
- Al-Jarrah Salsabeel
- Al-Kasaji Farah
- Al-Khaddar Ziad
- Al-Latayfeh Motasem
- Al-Madhrahi Ahmed
- Al-Maghrabi Sanabel
- Al-Mahdi Shehab
- Al-Mahmeed Husain
- Al-Manaseer Balqees Mahmoud
- Al-Mandeel Hazem
- Al-Maqtari Sahar
- Al-Masari Hayder
- Al-Masood Mohammed
- Al-Masri Mahmoud
- Al-Maswari Sakhr Abdulhakeem
- Al-Mohammad Abdulrahman
- Al-Mouakeh Ahmad
- Al-Mujaini Abdullah
- Al-Mukhaizeem Youssef
- Al-Naggar Hamza
- Al-Najjar Dania
- Al-Najjar Hani
- Al-Nawas Bilal
- Al-Oqabi Ayman
- Al-Oribi Saeid
- Al-Osta Malk
- Al-Othman Hadeel
- Al-Qannas Mohammad
- Al-Qannass Ali
- Al-Qattan Mohammad
- Al-Qurashi Qusay
- Al-Radi Osman
- Al-Raimi Ibrahim
- Al-Ramli Wisam
- Al-Rashdi Aya
- Al-Saadi Nina
- Al-Saban Rafat
- Al-Sabbagh Yusra
- Al-Shaiji Tariq
- Al-Shaikh Ghadeer
- Al-Shammakh Sonds
- Al-Shaye Ahmad
- Al-Shazly Mohammed Hamdy
- Al-Shehari Mohammed
- Al-Shibi Abdallah
- Al-Shudifat Abdel-Ellah
- Al-Sihan Mutlaq
- Al-Slaibi Ibrahim
- Al-Sukaini Ahmad
- Al-Surimi Dhyia Alhuq
- Al-Tamimi Yahia
- Al-Tarakji Mohannad
- Al-Terki Abdullatif
- Al-Thaher Mohammad
- Al-Urfan Mohammed
- Al-Uzri Muntadhir
- Al-Wandi Amna Salam
- Al-Yahri Omer
- Al-Yaseen Mustafa
- Al-Zaazaai Zakarya Abdullah
- Al-Zazay Karim
- Al-Zyadat Reham
- Alaa Sherif
- Alabbad Jasim
- Alabbasi Amira
- Alabdulkarim Yousof
- Alabi Ibrahim Abolaji
- Alabras Mohamad
- Aladaileh Ammar
- Aladawi Omar
- Alade Samuel
- Aladelusi Timothy
- Alafif Ali
- Alaglan Abeer
- Alahaidib Adel
- Alahdal Hani
- Alahmad Feras
- Alahmadi Ibrahim
- Alahmari Ahmed
- Alahmed Salman
- Alajaji Nouf
- Alajalen Amer
- Alajmi Suha
- Alajmi Turki
- Alakaloko Felix
- Alakeel Deem
- Alakhdury Amira
- Alaktaa Mohamed
- Alalawi Yousef
- Alali Mohammed
- Alam Ahmad Seraj
- Alam Azhar
- Alam Junaid
- Alam Mahmood
- Alam Mohammed Shadrul
- Alam Muhammad
- Alam Ruhina
- Alame Walid
- Alameen Hind
- Alameer Ehab
- Alammari Samer
- Alamri Ahmed
- Alamri Ossama
- Alannaz Omar
- Alaqeely Khalid
- Alaqel Sara
- Alarabi Alarabi
- Alarabi Rehab
- Alaradi Zuhair
- Alarcón Isaias
- Alarood Salameh
- Alarza Raquel
- Alasadi Ala
- Alasia Datonye
- Alasmari Mohammed
- Alassaf Mohammad
- Alassiri Ali
- Alatar Abdullah
- Alateeq Mohammed
- Alatiiga John Abanga
- Alatise Olusegun Isaac
- Alattas Zainab
- Alawadhi Abdulbari
- Alawadi Khalid
- Alawami Huda
- Alawami Mohammed
- Alawi Ahmed
- Alawi Khalil
- Alawneh Fade
- Alawneh Yazan
- Alayan Mohammed
- Alayande Barnabas
- Alayed Ahmad
- Alayed Nada
- Alayyoubi Hala
- Alazab Emad
- Alazabi Basma
- Alazzeh Ghaleb
- Alba J Jr
- Albaba Basil
- Albadawi Ismail
- Albader Ibtisam
- Albadi Zamzam
- Albaini Obey
- Albaiti Adel
- Albakry Ibrahim
- Albanese Erminia
- Albanopoulos Konstantinos
- Albargawi Ali
- Albarrak Abdullah
- Albarrak Majed
- Albasheer Mohammad
- Albastaki Aysha
- Albawardy Nof
- Albdah Abdullah
- Albendary Mohamed
- Alberici Laura
- Alberkamy Abdelrahman
- Albers Kim
- Albertsmeier Markus
- Albiol Maria Teresa
- Albishty Nouran
- Alborzi Majid
- Alburakan Ahmed
- Alburayh Bader
- Albzzaz Asem
- Alconchel Felipe
- Aldaghiri Khalid
- Aldahma Mohamed
- Aldakhil Ahmad
- Aldakhyel Lateefa
- Aldakkan Abdulrahman
- Aldalal Shuaib
- Aldana Joel
- Aldebeyan Wassim
- Alderazi Amer
- Aldhaam Naif
- Aldhurais Amirah
- Aldlyami Ehab
- Aldressi Wafa
- Aldridge Kerrie
- Aldrighetti Luca Antonio
- Aldulaijan Fozan
- Aldumaini Hamdan
- Ale Omolabake
- Alecci Anna
- Aleem Muhammad
- Alegbeleye Justina Omoikhefe
- Aleksandrova Evgeniya
- Aleksić Lidija
- Alelwany Aisha
- Alemanno Giovanni
- Alemu Berhanu
- Alemu Megersa
- Alemán María
- Alesmail Abdulkarim
- Alexakis Nicholas
- Alexander Dinesh
- Alexander Golomidov
- Alexander Philip
- Alexander Tamara
- Alexander Thomas
- Alexandrou Andreas
- Alexe Vlad
- Alfarah Mohammad
- Alfaro Hilda
- Alfaro Valeria Cormane
- Alfaro-Goldaracena Alejandro
- Alfarra Dina
- Alfayez Fatema
- Alfeqeeh Ahmed
- Alferdaus Abdallah
- Alfieri Alex
- Alfieri Sergio
- Alford Stephanie
- Alfraidy Doaa
- Algadi Noran
- Algar-Yañez Barbara
- Algarni Mohammed
- Algarni Saad
- Alghafour Tayma
- Alghamdi Abdulaziz
- Alghamdi Abdullah A
- Alghamdi Ahmad
- Alghamdi Ibtihal
- Alghamdi Rami
- Alghamdi Susan
- Alghazal Thabet
- Alghazo Abdallah
- Alghuson Lolowah
- Alhabdan Sultan
- Alhaddad Amani
- Alhaddad Wafa
- Alhadeethi Ahmed
- Alhadi Abdulmueti
- Alhag Albrra
- Alhaidari Ammar
- Alhaje Awatif
- Alhajji Zahrah
- Alhakami Nuraddin
- Alhalal Hani
- Alhami Haneen Ahmad
- Alhamid Ahmad
- Alhamid Aos
- Alhamid Mohammad
- Alhammad Othman
- Alhammali Tariq
- Alharthi Bandar
- Alharthi Mohammed
- Alharthi Nawaf
- Alharthi Sultan
- Alhasan Hasan
- Alhassan Basmah
- Alhassoun Turki
- Alhathal Naif
- Alhattab Majd
- Alhawatmeh Mohammad
- Alhazmi Alaa
- Alhazmi Barrag
- Alhazzaa Norah
- Alhefdhi Amal
- Alhelal Boshra
- Alhelal Fahad
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- Ali Ahmed
- Ali Ahsan
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- Moagal Rehab Al
- Moawad Karim Abdelraouf
- Mohamed Mohamed Ali
- Mohsen Mustafa Abo
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- Muhfouz Dima Abu
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- Murgueitio Natalia Cortes
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- Nwijy Khaled Ai
- Obead Hamza Abu
- Oliver Renato Aguera
- Omair Shehanah Al
- Otaibi Faisal Al
- Picciochi Maria
- Pinto João Almeida
- Polo Miriam Abdulkarim
- Qadhi Hani Al
- Qudhaya Rashed Al
- Qureshi Talha Ahmed
- Rahim Norazila
- Rahman Noorneza Abdul
- Rahman Norhafiza
- Raisi Amani Al
- Rashed Asmaa Al
- Rego Juliana Almeida
- Riaz Shujat Ahmed
- Riobello Eva Andreu
- Riyami Nihal Al
- Riyami Salim Al
- Ros Conrado Andrés
- Roselló Irene Vives
- Rubio Eva Corral
- Rueda Ignacio Alcalá
- Saad Sarah Ahmed
- Sabti Hilal Al
- Saez Iago Alvarez
- Saied Ghiath Al
- Salam Omar Abdul
- Salama Ibrahim Abdelkader
- Sanany Ghadeer Al
- Santos Daniel Costa
- Sayed Mohamed Al
- Sebastian Isabel Alonso
- Shaalah Ahmed Abdullah
- Shaibi Maha Al
- Shaikh Shafqat Ali
- Shanab Ahmed Abo
- Sharie Ahmed Al
- Shukri Asmaa Al
- Simoes Joana
- Smadi Omar Al
- Soares Rui Costa
- Soucheiron Maria Coronas
- Subaie Saud Al
- Suyyagh Kais Al
- Tarieh Ammar Abu
- Torres Eva Alvarez
- Victoria Czarlo Dela
- Villamayor Verónica Alen
- Vinayagam Raman
- Vincenti Cara
- Vincenzi Matteo
- Vinz Franziska
- Violante Tommaso
- Violas Philippe
- Violette Mukanyange
- Viotti Fabio
- Virdi Amrita
- Virgilio Edoardo
- Virgincar Ashwini
- Virta Ville P
- Viscido German
- Vishnoi Jeewan Ram
- Vishwakarma Sunil Kumar
- Vishwani Vartika
- Vissapragada Ravi
- Viste Claire
- Viswanath Yks
- Vitowanu Julius
- Viveiros Octavio
- Viveros-Carreño David
- Vives Inmaculada
- Vives-Barquiel Marian
- Vivian-Taylor Josephine
- Vix Michel
- Vlad Ioan Catalin
- Vlad Schitcu
- Vladimir Novgorodskii
- Vleminckx Nils
- Vo Uyen Giao
- Vogel Jon
- Vogel Keianna
- Vogel Rachel
- Vogelsang Holger
- Vogler Thomas
- Vogt Kelly
- Vohra Ravinder
- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub M.
- A. Adam M.
- A. Nassar M.
- A. Nemer A.
- Aahlin E. K.
- Ab Rahim M. F.
- Abad Gurumeta A.
- Abad-Motos A.
- Abang Jamari D. Z. H.
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- Abbas M. M.
- Abbasy J.
- Abbosh A.
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- Zulu S.
- Zumbakys Z.
- Zupan D.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
- Author
- Abdullah A Al Rabeeah MBBS
- Abdullah S Terkawi MD
- Abdullatif Husseini PhD
- Abdulwahab A Al-Nehmi MD
- Abla Mehio-Sibai PhD
- Adnan M Durrani MD
- Adrienne Chew ND
- Alaa Badawi PhD
- Alem Mehari MD
- Ali A Mokdad MD
- Ali S Akanda PhD
- Alireza Esteghamati MD
- Amany H Refaat PhD
- Amare Deribew PhD
- Amir Kasaeian PhD
- Amir Radfar MD
- Amira Shaheen PhD
- Amit R Bhakta MD
- Andrea B Feigl ScD
- Anil Kaul MD
- Anwar Rafay MS
- Ardeshir Khosravi PhD
- Aref A Bin Abdulhak MD
- Arjun Lakshmana Balaji MPH
- Ashkan Afshin DSc
- Aslam Pervaiz MHA
- Azmeraw T Amare MPH
- Babak Eshrati PhD
- Barthelemy Kuate Defo PhD
- Caitlyn Steiner MPH
- Charbel El Bcheraoui PhD
- Deena Alasfoor MSc
- Ejaz A Khan MPH
- Emmanuel K Peprah PhD
- Eric L Ding ScD
- Fadia S AlBuhairan MD
- Faiez Zannad MD
- Farah Daoud BS
- Faris H Al Lami PhD
- Farshad Farzadfar MD
- Farshad Pourmalek PhD
- Florian Fischer MPH
- Fortuné G Gankpé MD
- George A Mensah MD
- Georges Saade MD
- Gholamreza Roshandel PhD
- Gregory A Roth MD
- Gulfaraz Khan PhD
- Habibolah Masoudi Farid MD
- Hadi Danawi PhD
- Haidong Wang PhD
- Hamid Asayesh PhD
- Hanan Al Ahmadi DrPH
- Hannah Kravitz BS
- Haseeb Nawaz MD
- Hayet Hamdouni PhD
- Heresh Amini MSPH
- Hilda L Harb MPH
- Ibrahim Ginawi MD
- Ibrahim Khalil MD
- Imad A D Faghmous MPH
- Irina Filip MD
- Jai Das MBA
- Jamal T Nasher MSc
- Jerry P Abraham MD
- Joseph Wagner BS
- Jost B Jonas MD
- Kara Estep MPA
- Karzan A Mohammad PhD
- Kawkab Shishani PhD
- Kazem Rahimi DM
- Kelly Cercy BS
- Kevin F O'Rourke MFA
- Khalid A Altirkawi MD
- Laith J Abu-Raddad PhD
- Lidia Sanchez-Riera PhD
- Mahboubeh Parsaeian PhD
- Maheswar Satpathy PhD
- Mahmoud A Alomari PhD
- Margaret Robinson BA
- Marwa Tuffaha MD
- Matthew M Coates BA
- Maziar Moradi-Lakeh MD
- Mazin J Al Khabouri PhD
- Melkamu Dedefo Gishu MS
- Mohamed Al-Thani FRCPCH
- Mohamed E Ibrahim MPhil
- Mohamed Magdy Abd El Razek MBBCh
- Mohammad A AlMazroa MD
- Mohammad Ali Sahraian MD
- Mohammad Alkhateeb RN
- Mohammad Hossein Forouzanfar PhD
- Mohammad Sadegh Hassanvand PhD
- Mohammad T Hedayati PhD
- Mohammad Tavakkoli MD
- Mohammad Y Saeedi PhD
- Mohammed O Basulaiman PhD
- Morteza Mansourian PhD
- Mostafa Qorbani PhD
- Muhammad Imran Nisar MSc
- Mustafa Z Younis DrPH
- Nader Jahanmehr PhD
- Nadim E Karam MD
- Nawal Al-Hamad PhD
- Neeraj Bedi MD
- Nega Assefa Kassa PhD
- Nihaya Al-Sheyab PhD
- Nima Hafezi-Nejad MD
- Niveen M E Abu-Rmeileh PhD
- Olalekan A Uthman PhD
- Palwasha Anwari MD
- Pauline Kim BA
- Pouria Heydarpour MD
- Prof. Alan D Lopez PhD
- Prof. Ali H Mokdad PhD
- Prof. Ali M Assabri PhD
- Prof. Carla Makhlouf Obermeyer DSc
- Prof. Chakib Nejjari PhD
- Prof. Christopher J L Murray DPhil
- Prof. Dima M Qato PhD
- Prof. Foad Abd-Allah MD
- Prof. Karen Sliwa PhD
- Prof. Maysaa El Sayed Zaki PhD
- Prof. Mohamed Hsairi MD
- Prof. Mohsen Naghavi PhD
- Prof. Randah R Hamadeh DPhil
- Prof. Saleem M Rana PhD
- Prof. Theo Vos PhD
- Prof. Vivekanand Jha DM
- Prof. Wagner Marcenes PhD
- Prof. Yousef Khader ScD
- Prof. Ziad A Memish MD
- Prof. Ziad Nahas MD
- Raghib Ali FRCP
- Raghid Charara MD
- Rahul Gupta MD
- Raimundas Lunevicius PhD
- Rajaa Al-Raddadi PhD
- Rajesh K Rai MPH
- Rami M Habash MPH
- Rana Asghar MD
- Reza Assadi PhD
- Reza Malekzadeh MD
- Ronny Westerman PhD
- Rupert R A Bourne FRCOphth
- Ryan M Barber BS
- Saad B Omer PhD
- Sadaf G Sepanlou MD
- Saeid Shahraz PhD
- Safa Abdalla MD
- Sajjad Ur Rahman FRCPCH
- Saleh F Aldhahri MD
- Samer Hamidi PhD
- Samia Alhabib PhD
- Sara Jaber MD
- Sara Sheikhbahaei MD
- Serge Resnikoff MD
- Seyed-Mohammad Fereshtehnejad MD
- Shadi Saleh PhD
- Shahrzad Bazargan-Hejazi PhD
- Shams Eldin A Khalifa MSc
- Shirina Alsowaidi FRCPC
- Soufiane Boufous PhD
- Sowmya R Rao PhD
- Suliman Alghnam PhD
- Syed Danish Ali BA
- Talal Bakfalouni MD
- Tawfik Khoja FRCP
- Tesfaye Setegn MPH
- Ubai Alsharif MPH
- Umar Bacha PhM
- Vafa Rahimi-Movaghar MD
- Walid Ammar PhD
- Yohannes Kinfu PhD
- Yousef Elshrek PhD
- Zulfa A Al Rayess ABFM
- Zulfiqar A Bhutta PhD
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/10/2016
- Field of study
Background: The eastern Mediterranean region is comprised of 22 countries: Afghanistan, Bahrain, Djibouti, Egypt, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arabia, Somalia, Sudan, Syria, Tunisia, the United Arab Emirates, and Yemen. Since our Global Burden of Disease Study 2010 (GBD 2010), the region has faced unrest as a result of revolutions, wars, and the so-called Arab uprisings. The objective of this study was to present the burden of diseases, injuries, and risk factors in the eastern Mediterranean region as of 2013.
Methods: GBD 2013 includes an annual assessment covering 188 countries from 1990 to 2013. The study covers 306 diseases and injuries, 1233 sequelae, and 79 risk factors. Our GBD 2013 analyses included the addition of new data through updated systematic reviews and through the contribution of unpublished data sources from collaborators, an updated version of modelling software, and several improvements in our methods. In this systematic analysis, we use data from GBD 2013 to analyse the burden of disease and injuries in the eastern Mediterranean region specifically.
Findings: The leading cause of death in the region in 2013 was ischaemic heart disease (90·3 deaths per 100 000 people), which increased by 17·2% since 1990. However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. The leading cause of disability-adjusted life-years (DALYs) was ischaemic heart disease for males and lower respiratory infection for females. High blood pressure was the leading risk factor for DALYs in 2013, with an increase of 83·3% since 1990. Risk factors for DALYs varied by country. In low-income countries, childhood wasting was the leading cause of DALYs in Afghanistan, Somalia, and Yemen, whereas unsafe sex was the leading cause in Djibouti. Non-communicable risk factors were the leading cause of DALYs in high-income and middle-income countries in the region. DALY risk factors varied by age, with child and maternal malnutrition affecting the younger age groups (aged 28 days to 4 years), whereas high bodyweight and systolic blood pressure affected older people (aged 60–80 years). The proportion of DALYs attributed to high body-mass index increased from 3·7% to 7·5% between 1990 and 2013. Burden of mental health problems and drug use increased. Most increases in DALYs, especially from non-communicable diseases, were due to population growth. The crises in Egypt, Yemen, Libya, and Syria have resulted in a reduction in life expectancy; life expectancy in Syria would have been 5 years higher than that recorded for females and 6 years higher for males had the crisis not occurred.
Interpretation: Our study shows that the eastern Mediterranean region is going through a crucial health phase. The Arab uprisings and the wars that followed, coupled with ageing and population growth, will have a major impact on the region's health and resources. The region has historically seen improvements in life expectancy and other health indicators, even under stress. However, the current situation will cause deteriorating health conditions for many countries and for many years and will have an impact on the region and the rest of the world. Based on our findings, we call for increased investment in health in the region in addition to reducing the conflicts.
Funding: Bill & Melinda Gates Foundation
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
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- NA N.A.
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- Wondoh Paul M.
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- Wong Hsu Ven
- Wong Jane J
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- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
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- Xanthopoulou Georgia
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- Yaghi Nadine
- Yaghi Yasmine
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- Yakushkina Al'ona
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- Yang P Zichu
- Yanikoglu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürsat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
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- Yildirim Reyyan
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- You Lucia
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- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdağ Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
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- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
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- Estalagem Inês
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- Fahmawee Toqa
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- Falato Armando
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- Falco Nicolò
- Fareleira Ana
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- Figueiredo Ana Gabriela
- Finlay Ben
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- Forero-Torres Alexander
- Fortuna Martins Sónia
- Foschi Diego
- Foster Deshka S
- Fox Benjamin
- Fragoso Marta
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- Garfinkle Richard
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- Ghonaim Mennatullah
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- Zabiyaka Mikhail
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- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research