1,237 research outputs found
Monte-Carlo modelling of multi-object adaptive optics performance on the European Extremely Large Telescope
The performance of a wide-field adaptive optics system depends on input design parameters. Here we investigate the performance of a multi-object adaptive optics system design for the European Extremely Large Telescope, using an end-to-end Monte-Carlo adaptive optics simulation tool, DASP, with relevance for proposed instruments such as MOSAIC. We consider parameters such as the number of laser guide stars, sodium layer depth, wavefront sensor pixel scale, actuator pitch and natural guide star availability. We provide potential areas where costs savings can be made, and investigate trade-offs between performance and cost, and provide solutions that would enable such an instrument to be built with currently available technology. Our key recommendations include a trade-off for laser guide star wavefront sensor pixel scale of about 0.7 arcseconds per pixel, and a field of view of at least 7 arcseconds, that EMCCD technology should be used for natural guide star wavefront sensors even if reduced frame rate is necessary, and that sky coverage can be improved by a slight reduction in natural guide star sub-aperture count without significantly affecting tomographic performance. We find that adaptive optics correction can be maintained across a wide field of view, up to 7 arcminutes in diameter. We also recommend the use of at least 4 laser guide stars, and include ground-layer and multi-object adaptive optics performance estimates
Optimised design of nested oblong tube energy absorbers under lateral impact loading
Dynamic lateral crushing of mild steel (DIN 2393) nested tube systems was conducted using a ZWICK ROELL impact tester. The tests were performed with impact velocities ranging between 3 and 5 m/s, achieved using a fixed mass impinging onto the specimens under the influence of gravity. The various nested tube systems consisted of one standard and one optimised design. Their crushing behaviour and energy absorption capabilities were obtained and analysed.
In addition to the experimental work, numerical simulations using the explicit code LS-DYNA were conducted; boundary conditions matching those observed in experiments were applied to the models. Results from the numerical method were compared against those obtained from experiments. An over-prediction in force-deflection responses was obtained from the numerical code. An attempt was made to explain this inconsistency on the basis of the formation of plastic hinges and the validity of strain rate parameters used in the Cowper Symonds relation. It was found that the optimised energy absorbers exhibited a more desirable force-deflection response than their standard counterparts due to a simple design modification which was incorporated in the optimised design
Inter-study reproducibility of arterial spin labelling magnetic resonance imaging for measurement of renal perfusion in healthy volunteers at 3 Tesla
Background:
Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetised blood as endogenous contrast. We studied the reproducibility of ASL MRI in normal volunteers.<p></p>
Methods:
ASL MRI was performed in healthy volunteers on 2 occasions using a 3.0 Tesla MRI scanner with flow-sensitive alternating inversion recovery (FAIR) perfusion preparation with a steady state free precession (True-FISP) pulse sequence. Kidney volume was measured from the scanned images. Routine serum and urine biochemistry were measured prior to MRI scanning.<p></p>
Results:
12 volunteers were recruited yielding 24 kidneys, with a mean participant age of 44.1 ± 14.6 years, blood pressure of 136/82 mmHg and chronic kidney disease epidemiology formula estimated glomerular filtration rate (CKD EPI eGFR) of 98.3 ± 15.1 ml/min/1.73 m2. Mean kidney volumes measured using the ellipsoid formula and voxel count method were 123.5 ± 25.5 cm3, and 156.7 ± 28.9 cm3 respectively. Mean kidney perfusion was 229 ± 41 ml/min/100 g and mean cortical perfusion was 327 ± 63 ml/min/100 g, with no significant differences between ASL MRIs. Mean absolute kidney perfusion calculated from kidney volume measured during the scan was 373 ± 71 ml/min. Bland Altman plots were constructed of the cortical and whole kidney perfusion measurements made at ASL MRIs 1 and 2. These showed good agreement between measurements, with a random distribution of means plotted against differences observed. The intra class correlation for cortical perfusion was 0.85, whilst the within subject coefficient of variance was 9.2%. The intra class correlation for whole kidney perfusion was 0.86, whilst the within subject coefficient of variance was 7.1%.<p></p>
Conclusions:
ASL MRI at 3.0 Tesla provides a repeatable method of measuring renal perfusion in healthy subjects without the need for administration of exogenous compounds. We have established normal values for renal perfusion using ASL MRI in a cohort of healthy volunteers.<p></p>
Computation with narrow CTCs
We examine some variants of computation with closed timelike curves (CTCs),
where various restrictions are imposed on the memory of the computer, and the
information carrying capacity and range of the CTC. We give full
characterizations of the classes of languages recognized by polynomial time
probabilistic and quantum computers that can send a single classical bit to
their own past. Such narrow CTCs are demonstrated to add the power of limited
nondeterminism to deterministic computers, and lead to exponential speedup in
constant-space probabilistic and quantum computation. We show that, given a
time machine with constant negative delay, one can implement CTC-based
computations without the need to know about the runtime beforehand.Comment: 16 pages. A few typo was correcte
The Johannesburg cardiac rehabilitation programme
Cardiac rehabilitation has become a generally accepted mode of treatment for patients suffering from coronary artery disease. The Johannesburg cardiac rehabilitation programme has started in 1982 and has rapidly grown to become one of the largest programmes in southern Africa. This paper describes the 387 patients admitted to the unit l;Ietween June 1986 and July 1988 and evaluates the effects of a combined exercise training and lifestyle modification programme. The mean age on admission was 55 years for males and 58 years for females. Most patients were from social classes I and 11. Myocardial infarction, coronary artery bypass graft and a combination of both were the most common reasons for admission (35,4%. 23% and 21,2% respectively). On admission 72,9% of patients were smokers, 26,3% had hypertension and 34,3% had hypercholesterolaemia. A 50% drop-out rate within 12 months of starting the programme was noted. An increase in peak oxygen uptake, weight and skinfold thickness reduction, and improvement in the lipogram were seen after 6 months in patients who complied well with the programme. Cardiac rehabilitation is a secondary preventive strategy that can complement traditional medical and surgical therapies
Analysis of nested tube type energy absorbers with different indenters and exterior constraints
The present work presents both numerically and experimentally the quasi-static lateral compression of nested systems with vertical and inclined side constraints. The force-deflection response of mild steel short tubes compressed using two types of indenterâs is examined. The variation in response due to these indenters and external constraints are illustrated and how these can contribute to an increase the energy absorbing capacity of such systems. The implicit version of the Finite Element code via ANSYS is used to simulate these nested systems and comparison of results is made with those obtained in experiments and were found to be in good agreement
A single model of traversable wormholes supported by generalized phantom energy or Chaplygin gas
This paper discusses a new variable equation of state parameter leading to
exact solutions of the Einstein field equations describing traversable
wormholes. In addition to generalizing the notion of phantom energy, the
equation of state generates a mathematical model that combines the generalized
phantom energy and the generalized Chaplygin gas models.Comment: 6 pages, no figure
Metallic tube type energy absorbers: a synopsis
This paper presents an overview of energy absorbers in the form of tubes in which the material used is predominantly mild steel and/or aluminium. A brief summary is also made of frusta type energy absorbers. The common modes of deformation such as lateral and axial compression, indentation and inversion are reviewed. Theoretical, numerical and experimental methods which help to understand the behaviour of such devices under various loading conditions are outlined. Although other forms of energy absorbing materials and structures exist such as composites and honeycombs, this is deemed outside the scope of this review. However, a brief description will be given on these materials. It is hoped that this work will provide a useful platform for researchers and design engineers to gain a useful insight into the progress made over the last few decades in the field of tube type energy absorbers
Possible wormholes in a brane world
The condition R=0, where R is the four-dimensional scalar curvature, is used
for obtaining a large class (with an arbitrary function of r) of static,
spherically symmetric Lorentzian wormhole metrics. The wormholes are globally
regular and traversable, can have throats of arbitrary size and can be both
symmetric and asymmetric. These metrics may be treated as possible wormhole
solutions in a brane world since they satisfy the vacuum Einstein equations on
the brane where effective stress-energy is induced by interaction with the bulk
gravitational field. Some particular examples are discussed.Comment: 7 pages, revtex4. Submitted to Phys. Rev.
Core Structure of Global Vortices in Brane World Models
We study analytically and numerically the core structure of global vortices
forming on topologically deformed brane-worlds with a single toroidally compact
extra dimension. It is shown that for an extra dimension size larger than the
scale of symmetry breaking the magnitude of the complex scalar field at the
vortex center can dynamically remain non-zero. Singlevaluedness and regularity
are not violated. Instead, the winding escapes to the extra dimension at the
vortex center. As the extra dimension size decreases the field magnitude at the
core dynamically decreases also and in the limit of zero extra dimension size
we reobtain the familiar global vortex solution. Extensions to other types of
defects and gauged symmetries are also discussed.Comment: 6 two column pages, 3 figure
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