262 research outputs found
Back to Orthoepia – Spelling in Pronunciation Instruction: “Words Commonly Mispronounced” by Learners of Six L1s
This is a continuation of Nowacka’s (2016) study on the importance of local and global errors and spelling in pronunciation instruction. Unlike in the previous research that focused on the performance of Polish learners only, respondents of six different nationalities are included, in search of some cross-national universals or absence of them. This study seeks to answer the following questions: whether there is a need to focus on spelling in a pronunciation course with learners representing six different L1s and if this is the case which graphophonemic / phonotactic rules of English should be explicitly taught to all of these learners and which ones might be L1 specific only. The intention is also to empirically confirm the existence of local errors in the performance of around 240 speakers and 50 more listeners, constituting 291 listeners of six nationalities (Kazakh, Malaysian, Polish, Turkish, Tajik and Ukrainian) and to confirm the usefulness of memorizing Sobkowiak’s (1996) ‘Words Commonly Mispronounced’ even for learners of different L1s
GEOSPATIAL DATA FOR ENERGY EFFICIENCY AND LOW CARBON CITIES – OVERVIEW, EXPERIENCES AND NEW PERSPECTIVES –
The use of Geographic Information Systems (GIS) and their integration with 3D city models have become a common and powerful asset of cities for planning, visualization and decision-making operations in the fields of energy management, energy efficiency as well as transportation, public infrastructures, etc. The use of such solutions in urban spaces is still confined and mainly applied to visualization purposes (e.g. Google Earth) although geodata and spatial analyses can solve many problems towards the creation of smart cities. This paper presents an overview of various activities using spatial and non-spatial energy-related data integrated with 3D city models into GIS environments. It reviews existing solutions and reports two ongoing projects which deal with geospatial data for better planning and management of energy efficient public lighting and almost zero-consumption public buildings
Safety, quality, and processing of fruits and vegetables
Nowadays, one of the main objectives of the fruit and vegetable industry is to develop innovative novel products with high quality, safety, and optimal nutritional characteristics in order to respond with efficiency to the increasing consumer expectations. Various emerging, unconventional technologies (e.g., pulsed electric field, pulsed light, ultrasound, high pressure, and microwave drying) enable the processing of fruits and vegetables, increasing their stability while preserving their thermolabile nutrients, flavour, texture, and overall quality. Some of these technologies can also be used for waste and by-product valorisation. The application of fast noninvasive methods for process control is of great importance for the fruit and vegetable industry. The following Special Issue \u201cSafety, Quality, and Processing of Fruits and Vegetables\u201d consists of 11 papers, which provide a high-value contribution to the existing knowledge on safety aspects, quality evaluation, and emerging processing technologies for fruits and vegetables
Case report: Acute pericarditis following hepatic microwave ablation for liver metastasis.
Hepatic microwave ablation (MWA) is a growing treatment modality in the field of primary and secondary liver cancer. One potential side effect is thermal damage to adjacent structures, including the pericardium if the hepatic lesion is located near the diaphragm. Hemorrhagic cardiac tamponade is known to be a rare but potentially life-threatening complication. Here we present the first case of cardiac complication following MWA treatment in a 55-year-old man who presented with late cardiac tamponade. Adequate and timely management is essential, and clinicians should be fully aware of the need to perform early transthoracic echocardiography to detect signs of pericardial effusion when cardiac involvement is suspected
System and method for synchronising a data processing network
A data processing system according to the invention comprising a group of at least a first and a second module, wherein each module has a data processing facility, a clock for timing data transmissions from the module to another module, a time-slot counter for counting a number of time slots which are available for transmission of data. The modules have a first operational state wherein the counted number of time slots is less than or equal to a predetermined number, in which operational state data transmission is enabled, and a second operational state wherein the number is in excess of the predetermined number, in which second operational state data transmission is disabled, Each module has a notifying facility for notifying when it is in the second operational state. The data processing system has at least one detecting facility that detects whether the other modules have notified that they are in the second operational state and the modules each have an initialization facility for resetting the time-slot counter when the module is in the second operational state and each of the other modules has notified that it is in the second operational state
The impact of pulsed electric field on the extraction of bioactive compounds from beetroot
Beetroot is a root vegetable rich in different bioactive components, such as vitamins, minerals, phenolics, carotenoids, nitrate, ascorbic acids, and betalains, that can have a positive effect on human health. The aim of this work was to study the influence of the pulsed electric field (PEF) at different electric field strengths (4.38 and 6.25 kV/cm), pulse number 10\u201330, and energy input 0\u201312.5 kJ/kg as a pretreatment method on the extraction of betalains from beetroot. The obtained results showed that the application of PEF pre-treatment significantly (p < 0.05) influenced the efficiency of extraction of bioactive compounds from beetroot. The highest increase in the content of betalain compounds in the red beet\u2019s extract (betanin by 329%, vulgaxanthin by 244%, compared to the control sample), was noted for 20 pulses of electric field at 4.38 kV/cm of strength. Treatment of the plant material with a PEF also resulted in an increase in the electrical conductivity compared to the non-treated sample due to the increase in cell membrane permeability, which was associated with leakage of substances able to conduct electricity, including mineral salts, into the intercellular space
Bioactive compounds from plants and by-products: Novel extraction methods, applications, and limitations
In recent years, numerous articles documenting bioactive components derived from diverse food sources have been published. Plant-based bioactive substances hold significant prospects for use as dietary supplements and functional foods because of their potential advantages for human health as antimicrobial, anticancer, anti-inflammatory, and antioxidant agents. Utilizing plant by-products as raw materials can also lower production costs and lessen environmental impacts. Thus, this review covered the bioactive substances found in plants and their by-products. The health benefits of bioactive compounds obtained from plant origins were also highlighted in this review. Furthermore, we concentrated on both conventional extraction techniques (e.g., Soxhlet, heat reflux, and maceration) and innovative extraction strategies for bioactive substances, including pulsed electric field (PEF), pressurized liquid, microwave-assisted, ultrasonic-assisted, and subcritical fluid methods. Higher yields obtained by novel extraction methods were found to be of primary interest, considering immediate beneficial economic outcomes. The potential applications of those bioactive substances in the food industry have been studied. Additionally, this investigation handled concerns regarding the challenges and limitations related to bioactive compounds. It is anticipated that the information covered in this review will prove to be a useful resource for the plant food processing sector in suggesting a cost-effective and environmentally friendly extraction technique that would turn plant wastes into a functional product with a high added value
Transcaval versus Supra-Aortic Vascular Accesses for Transcatheter Aortic Valve Replacement: A Systematic Review with Meta-Analysis.
A growing body of evidence suggests that extrathoracic vascular accesses for transcatheter aortic valve replacement (TAVR) yield favorable outcomes and can be considered as primary alternatives when the gold-standard transfemoral access is contraindicated. Data comparing the transcaval (TCv) to supra-aortic (SAo) approaches (transcarotid, transsubclavian, and transaxillary) for TAVR are lacking. We aimed to compare the outcomes and safety of TCv and SAo accesses for TAVR as alternatives to transfemoral TAVR. A systematic review with meta-analysis was performed by searching PubMed/MEDLINE and EMBASE databases for all articles comparing TCv-TAVR against SAo-TAVR published until September 2023. Outcomes included in-hospital or 30-day all-cause mortality (ACM) and postoperative complications. A total of three studies with 318 TCv-TAVR and 179 SAo-TAVR patients were included. No statistically significant difference was found regarding in-hospital or 30-day ACM (relative risk [RR] 1.04, 95% confidence interval [CI] 0.47-2.34, p = 0.91), major bleeding, the need for blood transfusions, major vascular complications, and acute kidney injury. TCv-TAVR was associated with a non-statistically significant lower rate of neurovascular complications (RR 0.39, 95%CI 0.14-1.09, p = 0.07). These results suggest that both approaches may be considered as first-line alternatives to transfemoral TAVR, depending on local expertise and patients' anatomy. Additional data from long-term cohort studies are needed
Cobalt(II) Bipyrazolate Metal-Organic Frameworks as Heterogeneous Catalysts in Cumene Aerobic Oxidation: A Tag-Dependent Selectivity
"This document is the Accepted Manuscript version of a Published Work that appeared in final form in Inorganic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://pubs.acs.org/doi/10.1021/acs.inorgchem.0c00481"[EN] Three metal-organic frameworks with the general formula Co(BPZX) (BPZX(2-) = 3-X-4,4'-bipyrazolate, X = H, NH2, NO2) constructed with ligands having different functional groups on the same skeleton have been employed as heterogeneous catalysts for aerobic liquid-phase oxidation of cumene with O-2 as oxidant. O-2 adsorption isotherms collected at p(O2) = 1 atm and T = 195 and 273 K have cast light on the relative affinity of these catalysts for dioxygen. The highest gas uptake at 195 K is found for Co(BPZ) (3.2 mmol/g (10.1 wt % O-2)), in line with its highest BET specific surface area (926 m(2)/g) in comparison with those of Co(BPZNH(2)) (317 m(2)/g) and Co(BPZNO(2)) (645 m(2)/g). The O-2 isosteric heat of adsorption (Q(2)) trend follows the order Co(BPZ) > Co(BPZNH(2)) > Co(BPZNO(2)). Interestingly, the selectivity in the cumene oxidation products was found to be dependent on the tag present in the catalyst linker: while cumene hydroperoxide (CHP) is the main product obtained with Co(BPZ) (84% selectivity to CHP after 7 h, p(O2) = 4 bar, and T = 363 K), further oxidation to 2-phenyl-2-propanol (PP) is observed in the presence of Co(BPZNH(2)) as the catalyst (69% selectivity to PP under the same experimental conditions).S.G., R.V., and M.M. acknowledge Universita dell'Insubria for partial funding. G.G. thanks the Italian MIUR through the PRIN 2017 Project Multi-e: Multielectron Transfer for the Conversion of Small Molecules: an Enabling Technology for the Chemical Use of Renewable Energy (20179337R7) for financial support. G.G. thanks the TRAINER project (Catalysts for Transition to Renewable Energy Future) ref. ANR-17-MPGA-0017 for support. C.P. thanks the University of Camerino and the Italian MIUR throughout the PRIN 2015 Project Towards a Sustainable Chemistry (20154 x 9ATP_002). This project has also received funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 641887 (project acronym: DEFNET) and the Spanish Government through projects MAT2017-82288-C2-1-P and Severo Ochoa (SEV-2016-0683). Professor Norberto Masciocchi (University of Insubria, Como, Italy) is acknowledged for fruitful discussions. The authors are also grateful to Dr. Giulia Tuci (CNR-ICCOM Florence, Italy) for help with the XPS curve fitting. The Microscopy Service of the Universitat Politècnica de València is gratefully acknowledged for the electron microscopy measurements.Nowacka, AE.; Vismara, R.; Mercuri, G.; Moroni, M.; Palomino Roca, M.; Domasevitch, K.; Di Nicola, C.... (2020). Cobalt(II) Bipyrazolate Metal-Organic Frameworks as Heterogeneous Catalysts in Cumene Aerobic Oxidation: A Tag-Dependent Selectivity. Inorganic Chemistry. 59(12):8161-8172. https://doi.org/10.1021/acs.inorgchem.0c00481S816181725912Fortuin, J. P., & Waterman, H. I. (1953). Production of phenol from cumene. Chemical Engineering Science, 2(4), 182-192. doi:10.1016/0009-2509(53)80040-0Luyben, W. L. (2009). Design and Control of the Cumene Process. Industrial & Engineering Chemistry Research, 49(2), 719-734. doi:10.1021/ie9011535Matsui, S., & Fujita, T. (2001). New cumene-oxidation systems. 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Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7
The transcription factor Pax7 plays a key role during embryonic myogenesis and in adult organisms in that
it sustains the proper function of satellite cells, which serve as adult skeletal muscle stem cells. Recently
we have shown that lack of Pax7 does not prevent the myogenic differentiation of pluripotent stem cells.
In the current work we show that the absence of functional Pax7 in differentiating embryonic stem cells
modulates cell cycle facilitating their proliferation. Surprisingly, deregulation of Pax7 function also
positively impacts at the proliferation of mouse embryonic fibroblasts. Such phenotypes seem to be
executed by modulating the expression of positive cell cycle regulators, such as cyclin E
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