157 research outputs found

    An Empirical Research: Strategic Direction’s Impact on Enterprise Innovation

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    自创新的概念提出以来,创新尤其是新知识应用和新技术发明,已经不再被看作经济发展的外生变量而游离在经济发展之外;相反的,创新已经被视作经济发展甚至是社会发展的原动力。 企业的创新战略关系到企业的生死存亡。有关创新的研究也成为学者的研究热点,在创新的相关研究方面,学者们主要从创新的概念界定、创新的分类、创新的影响因素以及破坏性创新的相关领域着重进行了研究和探讨。前人关于创新的研究,更多的是对创新分类和现象的描述,其理论研究较为丰实,但是实证研究稍显匮乏;前人关于破坏性创新和维持性创新等的研究,有对概念的界定和内涵的综述等理论研究,但是对于破坏性创新的前因变量的研究较少,对于如何促进破坏性创新这一...Since the concept of innovation be put forward, Innovation, in particular, the invention of new knowledge and new technology has no longer been seen as the economic development of the exogenous variables of economic development; On contrary, innovation has been regarded as driving force of economic development even the driving force of social development. Innovative strategies are related to ...学位:管理学硕士院系专业:管理学院企业管理系_企业管理(含财务管理、市场营销、人力资源管理)学号:1762009115107

    Numerical simulations of the Cahn-Hilliard equation by large time-stepping methods

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    Cahn-Hilliard方程最初用来模拟二元合金在淬火到一种不稳定状态时所发生的相分离现象,随着理论的发展,它在其它领域也得到广泛应用。例如Spinodal分解问题,Fickian扩散问题,二相流问题以及相排序动力学等问题均可用Cahn-Hilliard方程来建模。由于该方程具有很强的非线性性质,构造高效的数值方法具有一定的难度。本文旨在考察最近由多位作者引入的所谓大时间步长方法,进一步研究附加的稳定项(被称为"A-项")对计算结果的影响。我们获得的主要结果如下:首先,针对Cahn-Hilliard方程的周期性问题,通过能量估计对其进行稳定性分析,证明了解的存在唯一性;其次,利用大时间步长离...The Cahn-Hilliard equation was originally introduced to describe phase separation of the molten binary alloy which is rapidly quenched to lower temperature, and then extensively applied to other fields such as Spinodal decomposition, Fickian diffusion, and two-phase flow.Both the fourth and the nonlinear terms make the Cahn-Hilliard equation stiff and difficult to solve numerically. In this pape...学位:理学硕士院系专业:数学科学学院信息与计算数学系_计算数学学号:20042303

    Approximation properties of modified q- Phillips operators

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    引进一类修正Q-PHIllIPS算子,并研究该算子列的一些逼近性质.得到算子列的一个kOrOVkIn型收敛定理,给出了算子列收敛速度的估计和一个VOrOnOVSkAJA型结果.In this paper,a kind of modified q- Phillips operators is introduced,some approximate properties of the operators are studied.A convergence theorem of Korovkin type is established.Also,an estimate for the rate of convergence and a Voronovskaja- type result are given.国家自然科学基金资助项目(61170324); 福建省自然科学基金资助项目(2014J01021); 福建省教育厅科技资助项目(2012JA12324

    A Convenient Method for Condon Adjustment by Using High-fidelity DNA Polymerase Amplification Property

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    在基因工程研究中,经常要涉及到对目的基因读码框进行调整的研究。本文报道了利用高保真DNA聚合酶扩增DNA后产生平末端的特性,及限制性内切酶对一重组的原核表达载体pET28a-HA进行读码框调整的研究,测序结果显示读码框按照预期设计正确调整,表明高保真DNA聚合酶可以用于DNA 3'凹陷端的补平,在DNA 3'凹陷端平滑化时多了一个有效的选择。The reading frame adjustment of target genes was often occurred in the study of gene engineering.The results of pET28-HA gene reading frame exactly adjustment showed high-fidelity DNA polymerase can be used generate blunt end from a DNA 5'-protruding end.The convenient method can be selected in the blunt of DNA 5'-protruding end

    制度变革、非正式制度与会计审计行为——中国会计学会英文期刊China Journal of Accounting Studies(CJAS)2018年第二次学术研讨会会议综述

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    2018年10月26日,由中国会计学会、中国会计学会对外交流专业委员会主办,厦门大学会计学系承办的中国会计学会对外学术交流专业委员会学术年会暨China Journal of Accounting Studies 2018年第二次学术研讨会在厦门大学隆重举行。来自复旦大学、中山大学、中国人民大学、西安交通大学、厦门大学、重庆大学、湖南大学、暨南大学、香港中文大学、香港城市大学、美国纽约州立大学石溪分校、澳大利亚新南威尔士大学、对外经贸大学、中央财经大学等三十多所境内外高等院校和研究机构的90余名专家学者参加了本次学术研讨会,围绕会议主题\"制国家自然科学基金重大项目课题“制度变革、非正式制度因素与会计审计行为研究”(71790602);;教育部人文社科基地重大项目“文化影响、会计信息质量与审计行为”(16JJD790032)资

    Therapeutic effects comparison between platelet-rich plasma and sodium hyaluronate intra-articular injection in treatment of knee osteoarthritis

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    目的关节腔内注射自体富血小板血浆(PRP)与透明质酸钠(SH),观察并比较其疗效。方法于2012年2月至12月,漳州市解放军第175医院骨科收治的81例Kellgren-Lawrence(KL)分级标准为Ⅱ、Ⅲ级膝关节骨关节炎的患者,年龄48~60岁,平均(52.6±3.6)岁;男性27例,女性53例;左膝38例,右膝43例。K-L分级标准,Ⅱ级47例,Ⅲ级34例,按就诊顺序序贯随机平行分为SH组(40例)和PRP组(41例),分别采用SH和PRP关节腔内注射进行治疗。治疗前和治疗后3、6、9、12个月对患者进行随访并进行美国西部Ontario与Mc Master大学骨关节炎指数(WOMAC)评分评估,两组间各时间点WOMAC评分比较采用t检验,两组内各时间点WOMAC评分比较采用重复测量方差分析;分别于治疗前和治疗后12个月进行膝关节磁共振检查,评价关节腔内积液的吸收情况。结果治疗前及治疗后3个月PRP组WOMAC评分[(48.42±4.95)分,(25.38±5.12)分]和SH组[(47.17±5.12)分,(25.17±5.09)分]比较,t值分别为-0.625和0.413,差异无统计学意义(P均〉0.05);治疗后6、9、12个月PRP组WOMAC评分[(21.44±4.73)分,(20.54±4.46)分,(16.53±7.35)分]和SH组[(25.87±5.16)分,(27.22±4.21)分,(29.63±8.21)分]比较,PRP组低于SH组,t值分别为-2.765、-3.447和-4.657,差异具有统计学意义(P均〈0.05),治疗后12个月复查磁共振,可见PRP组的关节积液吸收例数高于SH组,差异有统计学意义(P〈0.05)。结论膝关节腔内注射自体PRP,临床效果优于透明质酸钠,中长期疗效好。Objective To compare the efficacy of platelet rich plasma (PRP) and sodium hyaluronate (SH) intra-articular injection in the patients with knee osteoarthritis of grade Ⅱand Ⅲ. Methods A total of 81 patients with knee osteoarthritis of grade Ⅱ and Ⅲ ( Kellgren-Lawrence standard) were randomly assigned to the PRP and SH group. All 81 patients were treated in the 175th hospital of PLA, Zhangzhon, with the average age of (52.6 ± 3.6) years. There were 27 males and 53 females. Forty cases in SH group and 41 cases in PRP group had got the complete follow-up. Both the two groups adopted 4 ml of 5% lidocaine for intra-articular injection. All the patients were prospectively evaluated before the treatment and at the 34 , 6th , 9th and 12th month after the treatment by the Western Ontario and McMaster Universities (WOMAC) osteoarthritis index. The swelling subsiding knee was observed. Between the two groups WOMAC scores were compared using t test at each time point, within the groups the scores were compared by repeated measures analysis of variance. The absorption of accumulated fluid in the joint cavity was observed and compared by MRI before and 12 months after the treatment. Results No serious adverse event was detected in the two groups. According to the follow-up evaluations, both the groups presented clinical improvements. The comparison between the two groups showed no statistically significant difference before therapy and three months after the treatment ( t =- 0. 625, 0. 413, P 〉 0. 05 ). Six months, nine months and 12 months after the treatment, WOMAC score in the PRP group[ (21.44 ±4. 73), (20. 54 ± 4. 46) ,(16. 53 ± 7. 35 ) pointsl were lower than the SH group[(25.87 ±5.16), (27.22 ±4.21), (29. 63 ± 8.21 ) points] ; the difference was statistically signifieant( t = - 2. 765, - 3. 447, - 4. 657, P 〈 0. 05 ). Conclusion PRP intra-artieular injection in the treatment of knee osteoarthritis of gradeⅡ and Ⅲ may be more suitable compared to南京军区医学科技创新重点课题项目(15ZD027

    ATP表面配合物化学修饰电极的电化学性质研究

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    Hight等在VO~(2+)-ATP等溶液体系中发现,当络合物被H_2O_2氧化时,极大地促进了被络合活化的ATP的水解。在这个电子传递与ATP水解相偶联的过程中,电子传递的途径是否流经ATP的磷酐键导致ATP水解这个问题仍不清楚。为阐明这个问题,我们设

    固氮酶反应中ATP驱动电子传递的化学模拟

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    MgATP与铁蛋白络合的esr、CD、~(31)PNMR等研究,都有助于支持蔡启瑞提出的MgATP是络合在铁蛋白活性中心Fe_4S_4~*原子簇上的这一论点。但由于Mortenson等发现MgATP能够敏化铁蛋白中的铁,使其易与亚铁螯合剂反应这一重要的实验事实以来,关于MgATP在铁蛋白的结合部位的研究,大多数研究者倾向于MgATP不是结合在铁蛋白

    Numerical modeling and biomechanical analysis of the human mitral valve

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    目的建立人体心脏二尖瓣仿真模型,模拟二尖瓣闭合的工作过程,分析二尖瓣各组件应力分布,探讨二尖瓣瓣叶和腱索的相互作用,并探寻腱索受力大小与腱索粗细之间的相关性。方法构建二尖瓣几何模型,在此基础上定义模型单元类型、材料属性、接触、载荷及约束,建立有限元模型,计算模型的应力、速度和位移等参数。结果瓣膜上的应力分布不均匀,后瓣叶亚区之间的裂口位置所受应力最大;不考虑腱索连接至瓣叶时,瓣叶负载后外翻至心房一侧;考虑腱索连接至瓣叶时,前、后瓣叶关闭良好;各腱索受力不同,与前瓣叶相连的支持腱索受力最大,腱索受力大小与腱索粗细之间的线性相关系数为0.954。结论瓣叶中心和后瓣叶亚区之间的裂口两处应力较大区域是临床上二尖瓣裂的常发生部位;与瓣叶相连的腱索可在瓣叶负载时,施加牵拉力使瓣叶不致发生翻转,前、后瓣叶恰好关闭;解剖结构粗壮的腱索受力较大。Objective To establish a numerical model of human mitral valve and simulate its closing process,so as to analyze stress distributions on the valve apparatuses,study the interaction between leaflets of mitral valve and chordae tendineae,and explore the relationship between the force of chordae tendineae and their thickness.Methods A geometric model of human mitral valve was constructed.On the basis of the geometric model,the finite element model was established by defining the element type,material attributes,contacts,loads and constraints.Parameters such as stress,velocity and displacement were calculated after solving the model.Results The stress distribution on the valve was non-uniform.The clefts between the scallops in the posterior leaflet were always under the highest load.When no chordae tendineae were attached,the leaflets turned over to the side of the atrium.When chordea tendineae were attached,the anterior and posterior leaflet could close up successfully.Different chordae tendineae applied different forces to the valve.The strut chorea tendineae attached to the anterior leaflet applied highest force among all the chordea tendineae.The correlation coefficient between the thickness of chordae tendineae and their force was 0.954.Conclusions The two zones with higher stresses,namely the center of the leaflet and the clefts between the three scallops in the posterior leaflet,are also the positions of mitral valve cleft in clinic.Chordea tendineae can apply the pulling force on the leaflets while the mitral valve is under load,thus the leaflets won't turn over to the side of atrium and the valve can close up in time.Chordea tendineae with thicker anatomic structure always apply a higher force on the leaflets.国家自然科学基金资助项目(61102137); 福建省自然科学基金资助项目(2011J01366); 福建省创新医学科研基金(2009-CXB-59
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