13 research outputs found

    Nodular amelanotic melanoma

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    We report a case of 65-year-old male patient who presented with multiple erythematous papules coalescing to form a nodular mass over posterior aspect of right thigh of six months duration. His general and systemic examinations were within normal range except for right inguinal lymphadenopathy. Biopsy from the lesion was done, which showed diffuse infiltrate of nests of atypical melanocytes extending upto reticular dermis. Malignant cells were positive for S100 and human melanin black 45(HMB 45). Hence, a diagnosis of amelanotic melanoma (AM) - Clarke level IV and TNM stage III was reached. MRI of involved leg showed fungating soft tissue mass in the posterolateral aspect of right thigh and metastatic right inguinal adenopathy. Fine needle aspiration cytology (FNAC) from the right inguinal nodes confirmed metastasis of melanoma. The patient was referred to oncosurgery department for further management

    ELASTIC CONSTANTS OF A STRESSED LAYER FROM SURFACE ACOUSTIC WAVE MEASUREMENTS

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    It is well known that the propagation of both bulk and surface acoustic waves (SAWs) is affected by the presence of static stresses, a phenomenon known as the acoustoelastic effect. Ultrasonic measurements of velocity therefore depend on the stresses within the material, as well the elastic constants and the density. Although the effect of stress on the velocity is small, many ultrasonic methods are sufficiently accurate to detect the changes involved. When inverting such measurements to obtain elastic constants, it is desirable to take the effect of stress into account. Similarly, when using ultrasonic methods to measure stress, it is necessary to have accurate values for the elastic constants. In practice, the material parameters of the ‘natural’, unstressed state are often either completely unknown or not known with sufficient accuracy (as is usually the case for residual stresses), or else cannot be assumed to be equal to bulk values (as in the case of layered materials). This is a major distinction between situations involving residual as opposed to applied stress, since a reference state of some description is always available in the latter case
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