357 research outputs found
Effect of the Combined Intervention with Passive Whole-Body Vibration and Auriculotherapy on the Quality of Life of Individuals with Knee Osteoarthritis Assessed by the WHOQOL-Bref: A Multi-Arm Clinical Trial
The aim of this study was to determine the effect on the quality of life of two non-pharmacological interventions isolated or in combination: (i) passive whole-body vibration exercise (WBVE), and (ii) auriculotherapy (AT). One hundred three participants with knee osteoarthritis (KOA) were allocated to: (a) a vibration group (WBVEG; n = 17) that performed WBVE (peak-to-peak displacement: 2.5 to 7.5 mm, frequency: 5 to 14 Hz, Peak acceleration: 0.12 to 2.95 g), two days/weekly for five weeks, (b) an AT group (ATG; n = 21), stimulation of three specific auriculotherapy points (Kidney, Knee and Shenmen) in each ear pavilion, (c) WBVE + AT (WBVE + AT; n = 20) and (d) respective control groups (WBVE_CG, n = 15; AT_CG, n = 12; WBVE + AT_CG, n = 18). The participants filled out the WHOQOL-bref Questionnaire before the first and after the last sessions. Statistical differences in the various domains of the WHOQOL-bref were not found. In conclusion, WBVE or AT alone or combined did not contribute in altering the quality of life of individuals exposed to these interventions
VigilĂąncia do cĂąncer em Mato Grosso: aspectos metodolĂłgicos e operacionais de um projeto de extensĂŁo/pesquisa
Objective: To describe the methodological and operational aspects of the Cancer Surveillance Project and its associated factors: population-based and hospital-based registry (VIGICAN), in Mato Grosso (MT). Methods: VIGICAN was divided into two projects: an extension one, which updated the data from the Population-Based Cancer Registry (RCBP) of MT in the period 2008 to 2016; and one of research, which collected primary data, through individual interviews and analysis of medical records of people with a diagnosis of cancer, aged 18 years or over, treated at reference hospitals for oncology. To analyze the factors associated with cancer, the following variables were collected: socioeconomic and demographic, social support, status and health behavior, and environmental exposure. Results: In the perĂod from 2008 to 2016, approximately one hundred thousand cases of cancer (incident and prevalent) were reported in the RCBP CuiabĂĄ and Interior. After validation procedures, fifty thousand incident cases were chosen. The survey interviewed 1,012 patients, 38.2% living in the municipalities of CuiabĂĄ and VĂĄrzea Grande, 60.4% in the interior of the state and 1.4% in other states. Preliminary data revealed that the majority were female (55.0%) and younger than 60 years (54.3%). Among those interviewed, 7.2% reported smoking tobacco, 15.5% consumed alcoholic beverages (15.5%) and 32.7% lived close to crops. Conclusion: The development of these projects allowed the integration of education with health services and will enable the recognition of specificities and different exposure scenarios and factors associated with cancer in the Mato Grosso territory.Objetivo: Descrever os aspectos metodolĂłgicos e operacionais do Projeto VigilĂąncia do CĂąncer e seus fatores associados: registro de base populacional e hospitalar (VIGICAN), em Mato Grosso (MT). MĂ©todos: O VIGICAN se desdobrou em dois projetos: um de extensĂŁo, que atualizou os dados dos Registros de CĂąncer de Base Populacional (RCBP) de MT no perĂodo de 2008 a 2016; e um de pesquisa, que coletou dados primĂĄrios, por meio de entrevistas individuais e anĂĄlise de prontuĂĄrios de pessoas com diagnĂłstico de cĂąncer, com 18 anos ou mais, atendidas em hospitais de referĂȘncia para oncologia. Para analisar os fatores associados ao cĂąncer, foram coletadas as seguintes variĂĄveis: socioeconĂŽmicas e demogrĂĄficas, suporte social, situação e comportamentos de saĂșde e exposição ambiental. Resultados: No perĂodo de 2008 a 2016, foram notificados nos RCBP CuiabĂĄ e Interior, aproximadamente, 100 mil casos de cĂąncer (incidentes e prevalentes). ApĂłs procedimentos de validação, foram eleitos 50 mil casos incidentes. A pesquisa entrevistou 1.012 pacientes, sendo 38,2% residentes nos municĂpios de CuiabĂĄ e VĂĄrzea Grande, 60,4% no interior do estado e 1,4% em outros estados. Os dados preliminares revelaram que a maioria era do sexo feminino (55,0%) e tinha menos de 60 anos (54,3%). Entre os entrevistados, 7,2% relataram fumar tabaco, 15,5% consumiam bebidas alcoĂłlicas (15,5%) e 32,7% moravam prĂłximos a lavouras. ConclusĂŁo: O desenvolvimento desses projetos permitiu a integração do ensino com os serviços de saĂșde e possibilitarĂĄ o reconhecimento das especificidades e diferentes cenĂĄrios de exposição e fatores associados ao cĂąncer do territĂłrio mato-grossense
Contribution of the carbohydrate-binding ability of Vatairea guianensis lectin to induce edematogenic activity
Vatairea guianensis lectin (VGL), Dalbergiae tribe, is a N-acetyl-galactosamine (GalNAc)/Galactose (Gal) lectin previously purified and characterized. In this work, we report its structural features, obtained from bioinformatics tools, and its inflammatory effect, obtained from a rat paw edema model. The VGL model was obtained by homology with the lectin of Vatairea macrocarpa (VML) as template, and we used it to demonstrate the common characteristics of legume lectins, such as the jellyroll motif and presence of a metal-binding site in the vicinity of the carbohydrate-recognition domain (CRD). Protein-ligand docking revealed favorable interactions with N-acetyl-D-galactosamine, D-galactose and related sugars as well as several biologically relevant N- and O-glycans. In vivo testing of paw edema revealed that VGL induces edematogenic effect involving prostaglandins, interleukins and VGL CRD. Taken together, these data corroborate with previous reports showing that VGL interacts with N- and/or O-glycans of molecular targets, particularly in those presenting galactosides in their structure, contributing to the lectin inflammatory effect. © 2017 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM
A list of land plants of Parque Nacional do CaparaĂł, Brazil, highlights the presence of sampling gaps within this protected area
Brazilian protected areas are essential for plant conservation in the Atlantic Forest domain, one of the 36 global biodiversity hotspots. A major challenge for improving conservation actions is to know the plant richness, protected by these areas. Online databases offer an accessible way to build plant species lists and to provide relevant information about biodiversity. A list of land plants of âParque Nacional do CaparaĂłâ (PNC) was previously built using online databases and published on the website "CatĂĄlogo de Plantas das Unidades de Conservação do Brasil." Here, we provide and discuss additional information about plant species richness, endemism and conservation in the PNC that could not be included in the List. We documented 1,791 species of land plants as occurring in PNC, of which 63 are cited as threatened (CR, EN or VU) by the Brazilian National Red List, seven as data deficient (DD) and five as priorities for conservation. Fifity-one species were possible new ocurrences for ES and MG states
Educação da classe trabalhadora brasileira: expressão do desenvolvimento desigual e combinado
Measurement of the cosmic ray spectrum above eV using inclined events detected with the Pierre Auger Observatory
A measurement of the cosmic-ray spectrum for energies exceeding
eV is presented, which is based on the analysis of showers
with zenith angles greater than detected with the Pierre Auger
Observatory between 1 January 2004 and 31 December 2013. The measured spectrum
confirms a flux suppression at the highest energies. Above
eV, the "ankle", the flux can be described by a power law with
index followed by
a smooth suppression region. For the energy () at which the
spectral flux has fallen to one-half of its extrapolated value in the absence
of suppression, we find
eV.Comment: Replaced with published version. Added journal reference and DO
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5â7 vast areas of the tropics remain understudied.8â11 In
the American tropics, Amazonia stands out as the worldâs most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13â15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazonâs biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the regionâs vulnerability to environmental change. 15%â18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
A Ă©tica do silĂȘncio racial no contexto urbano: polĂticas pĂșblicas e desigualdade social no Recife, 1900-1940
Mais de meio sĂ©culo apĂłs o preconceito racial ter se tornado o principal alvo dos movimentos urbanos pelos direitos civis nos Estados Unidos e na Ăfrica do Sul, e dĂ©cadas depois do surgimento dos movimentos negros contemporĂąneos no Brasil, o conjunto de ferramentas legislativas criado no Brasil para promover o direito Ă cidade ainda adere Ă longa tradição brasileira de silĂȘncio acerca da questĂŁo racial. Este artigo propĂ”e iniciar uma exploração das raĂzes histĂłricas desse fenĂŽmeno, remontando ao surgimento do silĂȘncio sobre a questĂŁo racial na polĂtica urbana do Recife, Brasil, durante a primeira metade do sĂ©culo XX. O Recife foi eĂ© um exemplo paradigmĂĄtico do processo pelo qual uma cidade amplamente marcada por traços negros e africanos chegou a ser definida polĂtica e legalmente como um espaço pobre, subdesenvolvido e racialmente neutro, onde as desigualdades sociais originaram na exclusĂŁo capitalista, e nĂŁo na escravidĂŁo e nas ideologias do racismo cientĂfico. Neste sentido, Recife lança luzes sobre a polĂtica urbana que se gerou sob a sombra do silĂȘncio racial.More than half a century after racial prejudice became central to urban civil rights movements in the United States and South Africa, and decades after the emergence of Brazilâs contemporary Black movements, Brazil's internationally recognized body of rights-to-the-city legislation still adheres to the country's long historical tradition of racial silence. This article explores the historical roots of this phenomenon by focusing on the emergence of racial silence in Recife, Brazil during the first half of the 20th Century. Recife was and remains a paradigmatic example of the process through which a city marked by its Black and African roots came to be legally and politically defined as a poor, underdeveloped and racially neutral space, where social inequalities derived from capitalist exclusion rather than from slavery and scientific racism. As such, Recife'sexperience sheds light on the urban policies that were generated in the shadow of racial silence
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