2,342 research outputs found
Differences in xylem and leaf hydraulic traits explain differences in drought tolerance among mature Amazon rainforest trees
Considerable uncertainty surrounds the impacts of anthropogenic climate change on the composition and structure of Amazon forests. Building upon results from two large-scale ecosystem drought experiments in the eastern Brazilian Amazon that observed increases in mortality rates among some tree species but not others, in this study we investigate the physiological traits underpinning these differential demographic responses. Xylem pressure at 50% conductivity (xylem-P50 ), leaf turgor loss point (TLP), cellular osmotic potential (πo ), and cellular bulk modulus of elasticity (ε), all traits mechanistically linked to drought tolerance, were measured on upper canopy branches and leaves of mature trees from selected species growing at the two drought experiment sites. Each species was placed a priori into one of four plant functional type (PFT) categories: drought-tolerant versus drought-intolerant based on observed mortality rates, and subdivided into early- versus late-successional based on wood density. We tested the hypotheses that the measured traits would be significantly different between the four PFTs and that they would be spatially conserved across the two experimental sites. Xylem-P50 , TLP, and πo , but not ε, occurred at significantly higher water potentials for the drought-intolerant PFT compared to the drought-tolerant PFT; however, there were no significant differences between the early- and late-successional PFTs. These results suggest that these three traits are important for determining drought tolerance, and are largely independent of wood density-a trait commonly associated with successional status. Differences in these physiological traits that occurred between the drought-tolerant and drought-intolerant PFTs were conserved between the two research sites, even though they had different soil types and dry-season lengths. This more detailed understanding of how xylem and leaf hydraulic traits vary between co-occuring drought-tolerant and drought-intolerant tropical tree species promises to facilitate a much-needed improvement in the representation of plant hydraulics within terrestrial ecosystem and biosphere models, which will enhance our ability to make robust predictions of how future changes in climate will affect tropical forests
Plant traits controlling growth change in response to a drier climate
This is the final version. Available on open access from Wiley via the DOI in this recordPlant traits are increasingly being used to improve prediction of plant function, including plant demography. However, the capability of plant traits to predict demographic rates remains uncertain, particularly in the context of trees experiencing a changing climate. Here we present data combining 17 plant traits associated with plant structure, metabolism and hydraulic status, with measurements of long-term mean, maximum and relative growth rates for 176 trees from the world’s longest running tropical forest drought experiment. We demonstrate that plant traits can predict mean annual tree growth rates with moderate explanatory power. However, only combinations of traits associated more directly with plant functional processes, rather than more commonly employed traits like wood density or leaf mass per area, yield the power to predict growth. Critically, we observe a shift from growth being controlled by traits related to carbon cycling (assimilation and respiration) in well-watered trees, to traits relating to plant hydraulic stress in drought-stressed trees. We also demonstrate that even with a very comprehensive set of plant traits and growth data on large numbers of tropical trees, considerable uncertainty remains in directly interpreting the mechanisms through which traits influence performance in tropical forests.Conselho Nacional de Desenvolvimento Científico e TecnológicoNatural Environment Research Council (NERC)Australian Research Council (ARC)European Union FP7Fundação de Amparo à Pesquisa do Estado de São Paul
Development of Potential Multi-Target Inhibitors for Human Cholinesterases and Beta-Secretase 1: A Computational Approach
Alzheimer’s disease causes chronic neurodegeneration and is the leading cause of dementia
in the world. The causes of this disease are not fully understood but seem to involve two essential
cerebral pathways: cholinergic and amyloid. The simultaneous inhibition of AChE, BuChE, and
BACE-1, essential enzymes involved in those pathways, is a promising therapeutic approach to treat
the symptoms and, hopefully, also halt the disease progression. This study sought to identify triple
enzymatic inhibitors based on stereo-electronic requirements deduced from molecular modeling
of AChE, BuChE, and BACE-1 active sites. A pharmacophore model was built, displaying four
hydrophobic centers, three hydrogen bond acceptors, and one positively charged nitrogen, and
used to prioritize molecules found in virtual libraries. Compounds showing adequate overlapping
rates with the pharmacophore were subjected to molecular docking against the three enzymes and
those with an adequate docking score (n = 12) were evaluated for physicochemical and toxicological
parameters and commercial availability. The structure exhibiting the greatest inhibitory potential
against all three enzymes was subjected to molecular dynamics simulations (100 ns) to assess the
stability of the inhibitor-enzyme systems. The results of this in silico approach indicate ZINC1733
can be a potential multi-target inhibitor of AChE, BuChE, and BACE-1, and future enzymatic assays
are planned to validate those results.PPBE and PPGCF/UEFS; Fundação de Amparo à Pesquisa
do Estado de Minas Gerais—FAPEMIG, grants APQ-02741-17, APQ-00855-19, APQ-01733-21, and
APQ-04559-22Conselho Nacional de Desenvolvimento Científico e Tecnológico—CNPq-Brazil,
grants 305117/2017-3, 426261/2018-6Fellowship of 2021 (grant 310108/2020-9
Solar Irradiance Forecasting Using Dynamic Ensemble Selection
Solar irradiance forecasting has been an essential topic in renewable energy generation. Forecasting is an important task because it can improve the planning and operation of photovoltaic systems, resulting in economic advantages. Traditionally, single models are employed in this task. However, issues regarding the selection of an inappropriate model, misspecification, or the presence of random fluctuations in the solar irradiance series can result in this approach underperforming. This paper proposes a heterogeneous ensemble dynamic selection model, named HetDS, to forecast solar irradiance. For each unseen test pattern, HetDS chooses the most suitable forecasting model based on a pool of seven well-known literature methods: ARIMA, support vector regression (SVR), multilayer perceptron neural network (MLP), extreme learning machine (ELM), deep belief network (DBN), random forest (RF), and gradient boosting (GB). The experimental evaluation was performed with four data sets of hourly solar irradiance measurements in Brazil. The proposed model attained an overall accuracy that is superior to the single models in terms of five well-known error metrics
Stand dynamics modulate water cycling and mortality risk in droughted tropical forest
Transpiration from the Amazon rainforest generates an essential water source at a global and local scale. However, changes in rainforest function with climate change can disrupt this process, causing significant reductions in precipitation across Amazonia, and potentially at a global scale. We report the only study of forest transpiration following a long-term (>10 year) experimental drought treatment in Amazonian forest. After 15 years of receiving half the normal rainfall, drought-related tree mortality caused total forest transpiration to decrease by 30%. However, the surviving droughted trees maintained or increased transpiration because of reduced competition for water and increased light availability, which is consistent with increased growth rates. Consequently, the amount of water supplied as rainfall reaching the soil and directly recycled as transpiration increased to 100%. This value was 25% greater than for adjacent nondroughted forest. If these drought conditions were accompanied by a modest increase in temperature (e.g., 1.5°C), water demand would exceed supply, making the forest more prone to increased tree mortality.This work is a product of UK NERC grant NE/J011002/1 to PM andMM, CNPQ grant 457914/2013-/MCTI/CNPq/FNDCT/LBA/ESE-CAFLOR to ACLD, an ARC grant FT110100457 to PM and a UKNERC independent fellowship grant NE/N014022/1 to LR. It waspreviously supported by NERC NER/A/S/2002/00487, NERC GR3/11706, EU FP5-Carbonsink and EU FP7-Amazalert to PM. RP acknowledges support of MINECO (Spain), grant CGL2014-5583-JIN
Search for the rare decays and
A search for the rare decay of a or meson into the final
state is performed, using data collected by the LHCb experiment
in collisions at and TeV, corresponding to an integrated
luminosity of 3 fb. The observed number of signal candidates is
consistent with a background-only hypothesis. Branching fraction values larger
than for the decay mode are
excluded at 90% confidence level. For the decay
mode, branching fraction values larger than are excluded at
90% confidence level, this is the first branching fraction limit for this
decay.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-044.htm
Evidence for the strangeness-changing weak decay
Using a collision data sample corresponding to an integrated luminosity
of 3.0~fb, collected by the LHCb detector, we present the first search
for the strangeness-changing weak decay . No
hadron decay of this type has been seen before. A signal for this decay,
corresponding to a significance of 3.2 standard deviations, is reported. The
relative rate is measured to be
, where and
are the and fragmentation
fractions, and is the branching
fraction. Assuming is bounded between 0.1 and
0.3, the branching fraction would lie
in the range from to .Comment: 7 pages, 2 figures, All figures and tables, along with any
supplementary material and additional information, are available at
https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-047.htm
Study of the production of and hadrons in collisions and first measurement of the branching fraction
The product of the () differential production
cross-section and the branching fraction of the decay () is
measured as a function of the beauty hadron transverse momentum, ,
and rapidity, . The kinematic region of the measurements is and . The measurements use a data sample
corresponding to an integrated luminosity of collected by the
LHCb detector in collisions at centre-of-mass energies in 2011 and in 2012. Based on previous LHCb
results of the fragmentation fraction ratio, , the
branching fraction of the decay is
measured to be \begin{equation*} \mathcal{B}(\Lambda_b^0\rightarrow J/\psi
pK^-)= (3.17\pm0.04\pm0.07\pm0.34^{+0.45}_{-0.28})\times10^{-4},
\end{equation*} where the first uncertainty is statistical, the second is
systematic, the third is due to the uncertainty on the branching fraction of
the decay , and the
fourth is due to the knowledge of . The sum of the
asymmetries in the production and decay between and
is also measured as a function of and .
The previously published branching fraction of , relative to that of , is updated.
The branching fractions of are determined.Comment: 29 pages, 19figures. All figures and tables, along with any
supplementary material and additional information, are available at
https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-032.htm
Effects of EGR rate on performance and emissions of a diesel power generator fueled by B7
This paper analyses the impacts of the application of an exhaust gas recirculation (EGR) system on the performance and emissions of a stationary, direct-injection diesel engine operating with diesel oil containing 7% biodiesel (B7). Experiments were carried out in a 49-kW diesel power generator with the adapted EGR system, and engine performance and emissions were evaluated for different load and EGR settings. The results were compared with the engine operating with its original configuration without the EGR system, and revealed a reduction of peak cylinder pressure and fuel conversion efficiency, mainly at high engine loads. The use of EGR caused opposite effects on carbon dioxide (CO2), carbon monoxide (CO) and total hydrocarbons (THC) emissions, depending on load and EGR rate, showing an increase in most situations. The application of EGR consistently reduced oxides of nitrogen (NOX) emissions, reaching a maximum reduction close to 30%. In general, the use of EGR increased CO2, CO and THC emissions at high loads. The use of 7.5% EGR was found to be at an adequate rate to simultaneously reduce CO, THC and NOX emissions at low and moderate loads, without major penalties on CO2 emissions and engine performance
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