Letramento em saúde: aplicativo "poderosa no parto" de educação para pessoas gestantes / Health literacy: "powerful in childbirth" education application for pregnant women

A meta 3.7 das Nações Unidas nos fala sobre a importância de integrar a saúde reprodutiva que já está presente nos programas e estratégias do Brasil, por isso as gestantes merecem atenção especial, principalmente aquelas que sofrem restrições e têm menos acesso aos métodos disponíveis para minimizar o desconforto durante o trabalho de parto . O objetivo deste trabalho é descrever o desenvolvimento e os próximos passos do aplicativo protótipo denominado “Poderosa no Parto” que visa promover o ensino-aprendizagem-avaliação do método psicoprofilático para auxiliar a pessoa gestante na preparação para o parto natural. A aplicação de ensino-aprendizagem foi orientada por enfermeiras especializadas no atendimento à gestante, combinando o uso de metodologias de desenvolvimento de Engenharia de Software, Design Instrucional Sistemático e Processo Unificado. O protótipo apresenta exercícios e instrumentos para lembrar as gestantes das técnicas e tem como objetivo conscientizar sobre a importância da participação, apresentando recursos que facilitam o melhor desempenho das atividades respiratórias com acompanhamento diário do desempenho. Este estudo visa contribuir para a educação em saúde para gestantes

Preliminary Development Plan Of The Alr, The Laser Rangefinder For The Aster Deep Space Mission To The 2001 Sn263 Asteroid

The Brazilian deep space mission ASTER, as temporarily named, plans to send a small spacecraft to encounter and investigate the triple asteroid 2001-SN263. The launch is scheduled (initially) to occur in 2015, arriving in 2018. The main motivation of the mission is the development of technology and expertise to leverage the national space sector. Within the scientific goals, the investigation of the still unknown asteroid 2001-SN263. The main project guideline is to aggregate the widest possible Brazilian involvement in the platform, the development and operation of subsystems, integration, payload, as well as in the tracking, navigation, guidance and control of the probe. To meet this guideline, among others, the decision for the development of a laser altimeter in Brazil to fly in the mission was taken. This effort is currently coordinated by a group of researchers from the aerospace engineering personnel of UFABC. This article presents the preliminary development plan for the design of this instrument, which was called ALR (ASTER Laser Rangefinder).33331338Araujo, R.A.N., Winter, O.C., Prado, A.F.B., De, A., Sukhanov, A., (2010) O Sistema Triplo De Asteróides 2001SN263: Dinâmica Orbital E Regiões De Estabilidade, , Trabalho apresentado no XV Colóquio Brasileiro de Dinâmica Orbital, Hotel Alpina, Teresópolis, RJ, BrasilBecker, T., Howell, E.S., Nolan, M.C., Magri, C., Physical Modeling of Triple Near-Earth Asteroid 153591(2001 SN263) (2008) American Astronomical Society, DPS Meeting #40, #28.06, 40, p. 437. , Bulletin of the American Astronomical SocietyCole, T.D., NEAR Laser Rangefinder: A tool for the mapping and topologic study of Asteroid 433 Eros (1998) JHU/APL Tech. Dig., 19 (2), pp. 142-157Hashimoto, T., Kubota, T., Mizuno, T., Light weight sensors for the autonomous asteroid landing of MUSES-C mission (2003) Acta Astronautica, 52 (2-6), pp. 381-388Nolan, M.C., Howell, E.S., Benner, L.A.M., Ostro, S.J., Giorgini, J.D., Magri, C., Margot, J., Shepard, M., Planetary Radar Imaging of Binary Asteroids (2008) Presentation in the Binary Asteroid Dynamics Workshop, , http://www.asu.cas.cz/~asteroid/paris/add-ons.htm, Observatory Meudon, Paris, France, fromReddy, V., Gaffey, M.J., Schaal, M., Takir, D., Physical Characterization of First Triplet Near-Earth Asteroid (153591) 2001 SN263 (2008) Asteroids, Comets, Meteors, , 2008 held July 14-18, In Baltimore, Maryland. LPI Contribution No. 1405, paper id. 8244Sukhanov, A.A., de Velho, H.F.C., Macau, E.E., Winter, O.C., The Aster project: Flight to a near-Earth asteroid (2010) Cosmic Research, 48 (5), pp. 443-450. , doi:10.1134/S0010952510050114Tsuno, K., Okumura, E., Katsuyama, Y., Mizuno, T., Hashimoto, T., Nakayama, M., Hashimoto, H., Lidar on board asteroid explorer Hayabusa (2006) Proc. 6th Internat. Conf. On Space Optics, , ESTEC, Noordwijk, The Netherlands (ESA SP-621, JuneWinter, O.C., de Araujo, R.A.N., de Prado, A.F.B.A., Sukhanov, A., A Study of the orbital dynamics of the asteroid 2001 SN263 (2010) Proceedings of the 9th Brazilian Conference on Dynamics Control and Their Applications. Serra Negra, SP, , http://www.sbmac.org.br/dincon/trabalhos/PDF/minisymposia/68649.pdf, ISSN 2178-3667, fro

Climate change and cultural resilience in late pre-Columbian Amazonia

The long term response of ancient societies to climate change has been a matter of global debate. Until recently, the lack of integrative studies between archaeological, palaeoecological, and palaeoclimatological data had prevented an evaluation of the relationship between climate change, distinct subsistence strategies, and cultural transformations across the largest rainforest of the world, Amazonia. Here, we review the most relevant cultural changes seen in the archaeological record of six different regions within Greater Amazonia during late pre-Columbian times. We compare the chronology of those cultural transitions with high-resolution regional palaeoclimate proxies, showing that, while some societies faced major reorganisation during periods of climate change, others were unaffected and even flourished. We propose that societies with intensive, specialised land-use systems were vulnerable to transient climate change. In contrast, land-use systems that relied primarily on polyculture agroforestry, resulting in the formation of enriched forests and fertile Amazonian Dark Earths in the long term, were more resilient to climate change

Phylogenetic Analysis of Bolivian Bat Trypanosomes of the Subgenus Schizotrypanum Based on Cytochrome b Sequence and Minicircle Analyses

The aim of this study was to establish the phylogenetic relationships of trypanosomes present in blood samples of Bolivian Carollia bats. Eighteen cloned stocks were isolated from 115 bats belonging to Carollia perspicillata (Phyllostomidae) from three Amazonian areas of the Chapare Province of Bolivia and studied by xenodiagnosis using the vectors Rhodnius robustus and Triatoma infestans (Trypanosoma cruzi marenkellei) or haemoculture (Trypanosoma dionisii). The PCR DNA amplified was analyzed by nucleotide sequences of maxicircles encoding cytochrome b and by means of the molecular size of hyper variable regions of minicircles. Ten samples were classified as Trypanosoma cruzi marinkellei and 8 samples as Trypanosoma dionisii. The two species have a different molecular size profile with respect to the amplified regions of minicircles and also with respect to Trypanosoma cruzi and Trypanosoma rangeli used for comparative purpose. We conclude the presence of two species of bat trypanosomes in these samples, which can clearly be identified by the methods used in this study. The presence of these trypanosomes in Amazonian bats is discussed

Evaluation of rK39 rapid diagnostic tests for canine visceral leishmaniasis : longitudinal study and meta-analysis

Canine visceral leishmaniasis is a vector-borne disease caused by the intracellular parasite Leishmania infantum. It is an important veterinary disease, and dogs are also the main animal reservoir for human infection. The disease is widespread in the Mediterranean area, and parts of Asia and South and Central America, and is potentially fatal in both dogs and humans unless treated. Diagnosis of canine infections requires serological or molecular tests. Detection of infection in dogs is important prior to treatment, and in epidemiological studies and control programmes, and a sensitive and specific rapid diagnostic test would be very useful. Rapid diagnostic tests (RDTs) have been developed, but their diagnostic performance has been reported to be variable. We evaluated the sensitivity of a RDT based on serological detection of the rK39 antigen in a cohort of naturally infected Brazilian dogs. The sensitivity of the test to detect infection was relatively low, but increased with time since infection and the severity of infection. We then carried out a meta-analysis of published studies of rK39 RDTs, evaluating the sensitivity to detect disease and infection. The results suggest that rK39 RDTs may be useful in a veterinary clinical setting, but the sensitivity to detect infection is too low for operational control programmes

Description of Even-Even Xe isotopes in the transitional region of IBM

Properties of Xe isotopes isotopes are studied in the U(5)O(6) transitional region of Interacting Boson Model (IBM-1). The energy levels and B(E2)transition rates are calculated via the affine SU(1,1)Lie Algebra. The agreement with the most recent experimental is acceptable. The evaluated Hamiltonian control parameters suggest a spherical to (/gamma)-soft shape transition and propose the Xe(A=130)nucleus as the best candidate for the E(5)symmetry.Comment: 15 pages,3 figures. I have received an email from the BJPH editor (Prof.Luiz Nunes de Oliveira)which order me to resubmit the final version of paper and note that, paper will appear in Volume 43 of the Brazilian Journal of Physic

The nuclear envelope protein, LAP1B, is a novel protein phosphatase 1 substrate

Protein phosphatase 1 (PP1) binding proteins are quintessential regulators, determining substrate specificity and defining subcellular localization and activity of the latter. Here, we describe a novel PP1 binding protein, the nuclear membrane protein lamina associated polypeptide 1B (LAP1B), which interacts with the DYT1 dystonia protein torsinA. The PP1 binding domain in LAP1B was here identified as the REVRF motif at amino acids 55-59. The LAP1B:PP1 complex can be immunoprecipitated from cells in culture and rat cortex and the complex was further validated by yeast co-transformations and blot overlay assays. PP1, which is enriched in the nucleus, binds to the N-terminal nuclear domain of LAP1B, as shown by immunocolocalization and domain specific binding studies. PP1 dephosphorylates LAP1B, confirming the physiological relevance of this interaction. These findings place PP1 at a key position to participate in the pathogenesis of DYT1 dystonia and related nuclear envelope-based diseases.publishe

Effectiveness of ophthalmic solution preservatives: a comparison of latanoprost with 0.02% benzalkonium chloride and travoprost with the sofZia preservative system

<p>Abstract</p> <p>Background</p> <p>Although in vitro and in vivo laboratory studies have suggested that benzalkonium chloride (BAK) in topical ophthalmic solutions may be detrimental to corneal epithelial cells, multiple short- and long-term clinical studies have provided evidence supporting the safety of BAK. Despite the conflicting evidence, BAK is the most commonly used preservative in ophthalmic products largely due to its proven antimicrobial efficacy. This study was designed to characterize the antimicrobial performance of two commonly used topical ocular hypotensive agents that employ different preservative systems: latanoprost 0.005% with 0.02% BAK and travoprost 0.004% with sofZia, a proprietary ionic buffer system.</p> <p>Methods</p> <p>Each product was tested for antimicrobial effectiveness by <it>European Pharmacopoeia </it>A (EP-A) standards, the most stringent standards of the three major compendia, which specify two early sampling time points (6 and 24 hours) not required by the <it>United States Pharmacopeia </it>or <it>Japanese Pharmacopoeia</it>. Aliquots were inoculated with between 10⁵and 10⁶colony-forming units of the test organisms: <it>Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans </it>and <it>Aspergillus brasiliensis</it>. Sampling and enumeration were conducted at protocol-defined time points through 28 days.</p> <p>Results</p> <p>BAK-containing latanoprost met EP-A criteria by immediately reducing all bacterial challenge organisms to the test sensitivity and fungal challenges within the first six hours while the preservative activity of travoprost with sofZia did not. Complete bacterial reduction by travoprost with sofZia was not shown until seven days into the test, and fungal reduction never exceeded the requisite 2 logs during the 28-day test. Travoprost with sofZia also did not meet EP-B criteria due to its limited effectiveness against <it>Staphylococcus aureus</it>. Both products satisfied United States and Japanese pharmacopoeial criteria.</p> <p>Conclusions</p> <p>Latanoprost with 0.02% BAK exhibited more effective microbial protection than travoprost with sofZia using rates of microbial reduction, time to no recovery for all challenges and evaluation against EP-A criteria as measures. The rapid and complete reduction of all microbial challenges demonstrates that antimicrobial activity of latanoprost with 0.02% BAK exceeds that of travoprost with sofZia preservative system in these products and provides a more protective environment in the event of contamination and subsequent exposure to microorganisms during use.</p