Associations between experiences of disrupted attachments and suicidal thoughts and behaviours: an interpretative phenomenological analysis

Suicide is a major public health concern and itsaetiology is complex. Evidence suggests that experiences of early disrupted attachment relationships with parents and family members are associated with later experiences of suicidal thoughts and behaviours (STB). However, no study has investigated this relationship from an inductive, interpretative and idiographic perspective. Objective: This paper explores the role of interpersonal relationships in STB among nine individuals who have attempted suicide. Method: Semi-structured face-to-face interviews were analysed using an interpretative phenomenological analysis approach. Results and conclusion: Two inter-related master themes were identified: 1) ‘challenging relationships as catalysts for STB’; and 2) ‘positive relationships as buffers against STB’. Findings indicate that experiences of early disrupted parent-child attachments may contribute to vulnerability for STB by shaping participants' perceptions of intimate others and themselves (internal working models). These working models, along with other environmental factors and life events, may increase the risk of STB through perceptions of defeat, entrapment, perceived burdensomeness and thwarted belongingness. Results also suggest that being exposed to respectful, caring, unconditionally accepting, reciprocal, trusting, and non-judgemental intimate adult relationships increase resilience and is associated with recovery from past STB and a reduction of current suicide risk. The theoretical and clinical implications are discussed

Automatic Segmentation of Dermoscopic Images by Iterative Classification

Accurate detection of the borders of skin lesions is a vital first step for computer aided diagnostic systems. This paper presents a novel automatic approach to segmentation of skin lesions that is particularly suitable for analysis of dermoscopic images. Assumptions about the image acquisition, in particular, the approximate location and color, are used to derive an automatic rule to select small seed regions, likely to correspond to samples of skin and the lesion of interest. The seed regions are used as initial training samples, and the lesion segmentation problem is treated as binary classification problem. An iterative hybrid classification strategy, based on a weighted combination of estimated posteriors of a linear and quadratic classifier, is used to update both the automatically selected training samples and the segmentation, increasing reliability and final accuracy, especially for those challenging images, where the contrast between the background skin and lesion is low

Risk Factors for new accidental falls in elderly patients at traumatology ambulatory center

Objective. To identify the risks factors for new accidental falls in elderly patients attended in the Traumatology Ambulatory of a University hospital in Rio Grande do Sul, Brazil. Methodology. Quantitative study of the type of multiple cases. Performed at the traumatology ambulatory, amongst fifteen elders that attended the inclusion criteria: age of sixty or more; patient at the traumatology ambulatory because of a fall motivated by accident, oriented and in conditions of answer an interview of data collectors. The data collection was made between April and June, 2013, with the Elderly Nursing Core Set scale (Lopes & Fonseca). The data analysis was made by a descriptive structure, which helped identify the existence of relation patterns among the cases. Results. The risk factors for new accidental falls identified with larger incidence amongst the elders studied were: impaired balance (15/15), age above 65 (11/15), use of antihypertensive drugs (9/15), absence of non-slip material at home environment (7/15), in seven cases; rugs scattered at the floor of the house (6/15). Conclusion. The combination of intrinsic and extrinsic factors that include the environmental risks is considered a much more relevant cause to occur the new falls. The minimization of the home dangers, allied to the control of the elder intrinsic factors, may reduce the risks of causes. In that sense, is necessary that the nursing team make available more attention to the elderly assisted at the ambulatories, mainly those with sequelae due to fall accidents

The relationship between adult attachment and suicidal thoughts and behaviors: a systematic review

We aimed to (1) determine the extent of the relationship between attachment and suicidal thoughts and behaviors (STB), (2) investigate whether any gender differences exist, and (3) conduct a theoretical synthesis of the included studies. A systematic search of the databases Web of Science; EBSCO Host Medical and Psychology-related resources, which includes CINAHL, Health Source: Nursing/Academic Edition, Psychology and Behavioral Sciences Collection, and PsycINFO; and EMBASE was conducted, with 52 studies meeting the inclusion criteria. While secure attachment acts as protective factor, insecure attachment orientations appear to be vulnerability factors compromising an individual’s capacity to cope with relationship issues, increasing suicide risk. There is insufficient evidence about gender differences. The theoretical synthesis suggests that attachment, interacting with other psychological traits in response to negative life events, acts as a vulnerability or protective factor for STB. Implications for treatment are also discussed

Graph analysis of semantic word association among children, adults, and the elderly

This study used graph analysis to investigate how age differences modify the structure of semantic word association networks of children and adults and if the networks present a small-world structure and a scale-free distribution which are typical of natural languages. Three age groups of Brazilian Portuguese speakers (children, adults and elderly people) participated in the experiment. Quantitative and qualitative measures suggested that adults and elderly speakers have similar network structures. Children's network showed fewer nodes, connections and clusters, and longer inter-node distances. All networks presented a small-world structure, but they did not show entirely scale-free distributions. These results suggest that from childhood to adulthood, there is an increase not only in the number of words semantically linked to a target but also an increase in the connectivity of the network

Adult attachment: investigating the factor structure of the Relationship Scales Questionnaire

Objective: In this study, we aimed to conduct an in‐depth psychometric investigation of the Relationships Scales Questionnaire (RSQ). Method: About 717 UK‐based participants responded to an online questionnaire (F = 540, M = 177; age range 18–66 years, M = 25, SD = 8.46). We conducted (a) a series of confirmatory factor analyses (CFA) to test previously published factor models of the RSQ, (b) traditional (exploratory factor analysis and confirmatory factor analysis) and contemporary (exploratory graph analysis) exploratory techniques, followed by (c) validity and reliability analyses. Results: Although the RSQ was developed to assess four categories of adult attachment (typological approach – i.e., secure, preoccupied, dismissing, and fearful), our findings do not support the hypothesis that the RSQ delivers a psychometrically consistent measure of adult attachment styles. Conclusion: The results of the present study suggest that a two‐dimensional approach (i.e., anxiety and avoidance) to assessing adult attachment is optimal

BEVERAGE LIGHTLY CARBONATED WITH LEMONGRASS

In recent years, there is a growing interest in nutraceuticals which provide health benefits and are alternative to modern medicine. Nutrients, herbals and dietary supplements are major constituents of nutraceuticals which make them instrumental in maintaining health, act against various disease conditions and thus promote the quality of life. Lemongrass (Cymbopogon citratus) has been used as a modulator of mood and cognitive function, with anxiolytic and antibacterial effect.  The aim of this work was to develop an innovative, non-dairy, functional beverage using herbal Lemon Balm extract as a natural ingredient which would also be antioxidant and anti-inflammatory capacity. It was used for the preparation of based a lemongrass infusion. Several based grouts were tested to produce a drink with a reduced sugar content. a pickle basis of sucrose and sucralose, which was prepared with heating at 85°C /15min was used. As additives were used malic acid, ascorbic acid and sodium benzoate. It was added to ice water cooling until it reaches 0˚C. We analyze physicochemical property, microbiological for 35 days and sensory evaluation on the 21 days of the final product. Thus, from the results, the product was characterized: total acidity = 0.01g/100mL, pH 3.9, soluble solids: 8.6 °Brix and absence of microbiological standard. The sensory results of this beverage showed greater preference and acceptability index. Given the general acceptance of the product, technical feasibility and quality, it is considered timely to enter the same market

Skin Lesion Segmentation Ensemble with Diverse Training Strategies

This paper presents a novel strategy to perform skin lesion segmentation from dermoscopic images. We design an effective segmentation pipeline, and explore several pre-training methods to initialize the features extractor, highlighting how different procedures lead the Convolutional Neural Network (CNN) to focus on different features. An encoder-decoder segmentation CNN is employed to take advantage of each pre-trained features extractor. Experimental results reveal how multiple initialization strategies can be exploited, by means of an ensemble method, to obtain state-of-the-art skin lesion segmentation accuracy

The Impact of Infectious Disease-Related Public Health Emergencies on Suicide, Suicidal Behavior, and Suicidal Thoughts:A Systematic Review

Background: Infectious disease-related public health emergencies (epidemics) may increase suicide risk, and high-quality evidence is needed to guide an international response. Aims: We investigated the potential impacts of epidemics on suicide-related outcomes. Method: We searched MEDLINE, EMBASE, PsycInfo, CINAHL, Scopus, Web of Science, PsyArXiv, medRxiv, and bioRxiv from inception to May 13–16, 2020. Inclusion criteria: primary studies, reviews, and meta-analyses; reporting the impact of epidemics; with a primary outcome of suicide, suicidal behavior, suicidal ideation, and/or self-harm. Exclusion criteria: not concerned with suicide-related outcomes; not suitable for data extraction. PROSPERO registration: #CRD42020187013. Results: Eight primary papers were included, examining the effects of five epidemics on suicide-related outcomes. There was evidence of increased suicide rates among older adults during SARS and in the year following the epidemic (possibly motivated by social disconnectedness, fears of virus infection, and concern about burdening others) and associations between SARS/Ebola exposure and increased suicide attempts. A preprint study reported associations between COVID-19 distress and past-month suicidal ideation. Limitations: Few studies have investigated the topic; these are of relatively low methodological quality. Conclusion: Findings support an association between previous epidemics and increased risk of suicide-related outcomes. Research is needed to investigate the impact of COVID-19 on suicide outcomes

Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening