Tidal disruption of satellites and formation of narrow rings

In this paper we investigate the formation of narrow planetary rings such as those found around Uranus and Saturn through the tidal disruption of a weak, gravitationally bound satellite that migrates within its Roche limit. Using $N$-body simulations, we study the behaviour of rubble piles placed on circular orbits at different distances from a central planet. We consider both homogeneous satellites and differentiated bodies containing a denser core. We show that the Roche limit for a rubble pile is closer to the planet than for a fluid body of the same mean density. The Roche limit for a differentiated body is also closer to the planet than for a homogeneous satellite of the same mean density. Within its Roche limit, a homogeneous satellite totally disrupts and forms a narrow ring. The initial stages of the disruption are similar to the evolution of a viscous fluid ellipsoid, which can be computed semi-analytically. On the other hand, when a differentiated satellite is just within the Roche limit only the mantle is disrupted. This process is similar to Roche-lobe overflow in interacting binary stars and produces two narrow rings on either side of a remnant satellite. We argue that the Uranian rings, and possibly their shepherd satellites, could have been formed through the tidal disruption of a number of protomoons that were formed inside the corotation radius of Uranus and migrated slowly inwards as a result of tidal interaction with the planet.Comment: Accepted for publication in MNRAS. Some figures have been compressed to fit into astro-ph size guidelines. Please contact authors if full resolution images are require

Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers

Gold nanoparticles, covalently functionalised with the photosensitiser C11Pc and PEG, were actively targeted towards epidermal growth factor receptor overexpressing cancers using the peptide FITC-βAAEYLRK. Selective phototoxicity was observed at nanomolar concentrations with minimal dark toxicity

Introduction: Politics, Geographies and Histories in Workers’ Education

Tamboukou, M., Introduction: Politics, Geographies and Histories in Workers’ Education, 2016, reproduced with permission of Palgrave Macmillan. This extract is taken from the author's original manuscript and has not been edited. The definitive, published, version of record is available here: http://www.palgrave.com/gb/book/9781137490148#aboutBoo

Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study

Background Early mobilisation (EM) is an intervention that may improve the outcome of critically ill patients. There is limited data on EM in COVID-19 patients and its use during the first pandemic wave. Methods This is a pre-planned subanalysis of the ESICM UNITE-COVID, an international multicenter observational study involving critically ill COVID-19 patients in the ICU between February 15th and May 15th, 2020. We analysed variables associated with the initiation of EM (within 72 h of ICU admission) and explored the impact of EM on mortality, ICU and hospital length of stay, as well as discharge location. Statistical analyses were done using (generalised) linear mixed-effect models and ANOVAs. Results Mobilisation data from 4190 patients from 280 ICUs in 45 countries were analysed. 1114 (26.6%) of these patients received mobilisation within 72 h after ICU admission; 3076 (73.4%) did not. In our analysis of factors associated with EM, mechanical ventilation at admission (OR 0.29; 95% CI 0.25, 0.35; p = 0.001), higher age (OR 0.99; 95% CI 0.98, 1.00; p ≤ 0.001), pre-existing asthma (OR 0.84; 95% CI 0.73, 0.98; p = 0.028), and pre-existing kidney disease (OR 0.84; 95% CI 0.71, 0.99; p = 0.036) were negatively associated with the initiation of EM. EM was associated with a higher chance of being discharged home (OR 1.31; 95% CI 1.08, 1.58; p = 0.007) but was not associated with length of stay in ICU (adj. difference 0.91 days; 95% CI − 0.47, 1.37, p = 0.34) and hospital (adj. difference 1.4 days; 95% CI − 0.62, 2.35, p = 0.24) or mortality (OR 0.88; 95% CI 0.7, 1.09, p = 0.24) when adjusted for covariates. Conclusions Our findings demonstrate that a quarter of COVID-19 patients received EM. There was no association found between EM in COVID-19 patients' ICU and hospital length of stay or mortality. However, EM in COVID-19 patients was associated with increased odds of being discharged home rather than to a care facility. Trial registration ClinicalTrials.gov: NCT04836065 (retrospectively registered April 8th 2021)

Management-driven evolution in a domesticated ecosystem

Millennia of human land-use have resulted in the widespread occurrence of what have been coined ‘domesticated ecosystems’. The anthropogenic imprints on diversity, composition, structure and functioning of such systems are well documented. However, evolutionary consequences of human activities in these ecosystems are enigmatic. Calluna vulgaris (L.) is a keystone species of coastal heathlands in northwest Europe, an ancient semi-natural landscape of considerable conservation interest. Like many species from naturally fire-prone ecosystems, Calluna shows smoke-adapted germination, but it is unclear whether this trait arose prior to the development of these semi-natural landscapes or is an evolutionary response to the anthropogenic fire regime. We show that smoke-induced germination in Calluna is found in populations from traditionally burnt coastal heathlands but is lacking in naturally occurring populations from other habitats with infrequent natural fires. Our study thus demonstrates evolutionary imprints of human land-use in semi-natural ecosystems. Evolutionary consequences of historic anthropogenic impacts on wildlife have been understudied, but understanding these consequences is necessary for informed conservation and ecosystem management

Marine renewable energy development:Assessing the Benthic Footprint at multiple scales

Increasing concerns over global climate change and sustainable fuel procurement are driving the search for new ways to derive energy from the seas. Globally, the offshore wind energy sector has progressed rapidly, and wave and tidal-current energy converters are now approaching deployment at commercial scales. To date, most studies of the ecological effects of marine renewable energy development have concentrated on birds and marine mammals. Here, we focus on the consequences for benthic flora and fauna, and for benthic habitats across a variety of scales. We use a "Benthic Footprint" concept to discuss the potential for species-specific environmental responses, and to consider the poorly understood cumulative effects of wind, wave, and tidalcurrent energy operations on marine ecosystems. Collaborations between ecologists, industry specialists, and government bodies, as well as better designs for devices, arrays, and developments consisting of multiple arrays, can contribute to the goal of reducing the Benthic Footprint of marine renewable energy, thereby facilitating large-scale implementation of these technologies.</p

Data from: Management-driven evolution in a domesticated ecosystem

Millennia of human land-use have resulted in the widespread occurrence of what have been coined ‘domesticated ecosystems’. The anthropogenic imprints on diversity, composition, structure and functioning of such systems are well documented. However, evolutionary consequences of human activities in these ecosystems are enigmatic. Calluna vulgaris (L.) is a keystone species of coastal heathlands in northwest Europe, an ancient semi-natural landscape of considerable conservation interest. Like many species from naturally fire-prone ecosystems, Calluna shows smoke-adapted germination, but it is unclear whether this trait arose prior to the development of these semi-natural landscapes or is an evolutionary response to the anthropogenic fire regime. We show that smoke-induced germination in Calluna is found in populations from traditionally burnt coastal heathlands but is lacking in naturally occurring populations from other habitats with infrequent natural fires. Our study thus demonstrates evolutionary imprints of human land-use in semi-natural ecosystems. Evolutionary consequences of historic anthropogenic impacts on wildlife have been understudied, but understanding these consequences is necessary for informed conservation and ecosystem management

Calluna smoke induced germination

Calluna smoke induced germinatio