Reversible tricolour luminescence switching based on a piezochromic iridium(iii) complex

On the basis of rational molecular design, the tricolour luminescence switching of an Ir(III) complex is achieved for the first time. The transformation between two crystalline states and an amorphous state is responsible for the switching behaviour of this complex between blue, green and yellow states. Solvent molecules are shown to play a crucial role in the crystallization and luminescence processes

New ionic dinuclear Ir(III) Schiff base complexes with aggregation-induced phosphorescent emission (AIPE)

Two new ionic dinuclear Ir(III) Schiff base complexes which are straightforward to synthesise have luminescence quantum yields as high as 37% in neat films. These are the first examples of dinuclear ionic Ir(III) complexes that display aggregation-induced phosphorescent emission (AIPE)

Intraosseous Nerve Sheath Tumors in the Jaws

Although the head and neck region is recognized as the most common location for peripheral nerve sheath tumors, central involvement, particularly in the jaw bones, is quite unusual. Neurofibroma is one of the most common nerve sheath tumors occurring in the soft tissue and generally appears in neurofibromatosis 1 (NF1 or von Recklinghausen's disease). Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon sarcomas that almost always arise in the soft tissue. Here, we report four cases of intraosseous peripheral nerve sheath tumors occurring in the jaw bones and compare the clinical, radiologic, and pathologic findings in order to make a differential diagnosis

Impact Resistance of Rubberized Alkali-Activated Concrete Incorporating Recycled Aggregate and Recycled Steel Fiber

Alkali-activated concrete (AAC) features excellent mechanical properties and sustainability. The incorporation of crumb rubber (CR), recycled concrete aggregates (RCAs), and recycled steel fibers (RSFs) can further enhance environmental sustainability. This paper mainly investigated the dynamic behaviors of a novel rubberized AAC incorporating RCAs and RSFs (RuAAC) through Split-Hopkinson Pressure Bar (SHPB) tests. The variables included three types of RSF content (1%, 2% and 3%), five types of rubber content (0%, 5%, 20%, 35% and 50%) and five impact pressures (0.5 MPa, 0.6 MPa, 0.7 MPa, 0.8 MPa and 0.9 MPa). Dynamic stress–strain curves, dynamic strength, the dynamic increase factor (DIF), impact toughness and the synergistic effects of RSF and CR were discussed. The results show that increasing RSF and CR contents could improve the impact resistance of RuAAC under impact loading. The RuAAC exhibited significant strain rate sensitivity, and the sensitivity increased with larger contents of RSF and CR. The increase in strain rate sensitivity was more pronounced with higher CR contents, which was reflected in larger dynamic increase factor (DIF) values. Under high impact pressure, the impact toughness was obviously enhanced with higher RSF contents, while the contribution of increased CR content to impact toughness was not apparent, which may be attributed to the fact that this study only calculated the integral under the dynamic stress–strain curve before the peak stress to determine impact toughness, neglecting the potential contribution of CR particles after the peak point. The obvious strain sensitivity exhibited by the RuAAC in the SHPB tests indicated superior impact performance, making it particularly suitable for architectural structures prone to seismic or explosive impacts

Polyurethane Derivatives for Highly Sensitive and Selective Fluorescent Detection of 2,4,6-Trinitrophenol (TNP)

A series of luminescent non-conjugated polyurethane derivatives (PUs) has been obtained in a facile way in high yields. The polymers show highly selective and sensitive detection of 2,4,6-trinitrophenol (TNP) (picric acid). The selectivity for TNP is accomplished via combination of a strong inner filter effect (IFE), Förster resonance energy transfer (FRET) and photoinduced electron transfer (PET). A convenient indicator paper for the visual detection of TNP has been constructed by immobilization of the polymer PU1 on filter paper. The PU1-coated filter paper presents a rapid detection of TNP in water with a low concentration limit of 10−10 M, ∼0.229 ag cm−2. This is a simple, low-cost and highly efficient method for the detection of TNP

New AIE-active dinuclear Ir(III) complexes with reversible piezochromic phosphorescence behaviour

Two new AIE-active dinuclear Schiff base Ir(III) complexes exhibit highly reversible piezochromic phosphorescence behaviour enabling the construction of a re-writable phosphorescence data recording device

Bright red aggregation-induced emission nanoparticles for multifunctional applications in cancer therapy

Developing multifunctional photosensitizers (PSs) is needed to effectively simplify cancer treatment, but it remains a big challenge. Here, two red-emitting AIE-active, donor–acceptor (D–A) PSs with small ΔEST and their AIE nanoparticles, are rationally designed and synthesized. The PS1 NPs exhibit bright red-emission with high quantum yield, appropriate 1O2 generation ability and good biocompatibility. More importantly, PS1 NPs can strongly light up the cytoplasm by gently shaking the cells for only 5 s at room temperature, indicating ultrafast staining and mild incubation conditions. In vitro and in vivo cell tracing demonstrate that PS1 NPs can track cells over 14 days, and effectively inhibit tumor growth upon irradiation. To the best of our knowledge, this work is the first example of a PS that integrates image-guided PDT, ultrafast staining and long-term tracing functions, demonstrating the “all-in-one” concept which offers great advantages for potential clinical application

AIE Multinuclear Ir(III) Complexes for Biocompatible Organic Nanoparticles with Highly Enhanced Photodynamic Performance

The singlet oxygen (1O2) generation ability of a photosensitizer (PS) is pivotal for photodynamic therapy (PDT). Transition metal complexes are effective PSs, owing to their high 1O2 generation ability. However, non‐negligible cellular toxicity, poor biocompatibility, and easy aggregation in water limit their biomedical applications. In this work, a series of red‐emitting aggregation‐induced emission (AIE) Ir(III) complexes containing different numbers of Ir centers (mono‐, di‐, and trinuclear) and the corresponding nanoparticles (NPs) AIE‐NPs, are designed and synthesized. The increase of 1O2 generation ability is in line with the increasing number of Ir centers. Compared with the pure Ir(III) complexes, the corresponding NPs offer multiple advantages: (i) brighter emission; (ii) higher phosphorescence quantum yields; (iii) longer excited lifetime; (iv) higher 1O2 generation ability; (v) better biocompatibility; and (vi) superior cellular uptake. Both in vitro and in vivo experiments corroborate that AIE‐NPs with three iridium centers possess potent cytotoxicity toward cancer cells and effective inhibition of tumor growth. To the best of knowledge, this work is the first example of NPs of multinuclear AIE Ir(III) complexes as PSs for enhanced PDT. This study offers a new method to improve the efficiency of PSs for clinical cancer treatments