Imaging of Hepatocellular Carcinoma by Computed Tomography and Magnetic Resonance Imaging: State of the Art

Hepatocellular carcinoma (HCC) is a very frequent tumor worldwide. Its incidence is linked to the distribution of liver cirrhosis and viral hepatitis, which are the main risk factors for the development of HCC. For the evaluation of the cirrhotic liver and for the diagnosis of HCC, multidetector computed tomography (MDCT) proved to be a robust and reliable tool. In MDCT the diagnosis of HCC can be made based on neovascularization with increased arterial and decreased portal venous supply. With modern magnetic resonance imaging (MRI), spatial resolution and robustness increased dramatically. Beside the evaluation of neovascularization by means of gadolinium-enhanced early dynamic MRI, the main advantages of MRI are additional information on tissue composition and liver-specific function. With diffusion-weighted imaging or plain T(1)- and T(2)-weighted sequences, different tissue elements like fat, hemorrhage, glycogen, edema and cellular density can be evaluated. Liver-specific contrast agents give insight into the Kupffer cell density or the hepatocellular function. The integration of all these parts into the MR examination allows for a very high detection rate for overt HCC nowadays, although very small HCCs are still a challenge. Moreover, insight into the different stages of hepatocarcinogenesis can be possible with MRI. Despite its limited availability in some countries, it has to be rendered to be the modality of choice for the distinct evaluation of the cirrhotic liver. Copyright (C) 2009 S. Karger AG, Base

Scanning Tunneling Spectroscopy and Vortex Imaging in the Iron-Pnictide Superconductor BaFe1.8_{1.8}Co0.2_{0.2}As2_2

We present an atomic resolution scanning tunneling spectroscopy study of superconducting BaFe$_{1.8}$Co$_{0.2}$As$_2$ single crystals in magnetic fields up to $9 \text{Tesla}$. At zero field, a single gap with coherence peaks at $\overline{\Delta}=6.25 \text{meV}$ is observed in the density of states. At $9 \text{T}$ and $6 \text{T}$, we image a disordered vortex lattice, consistent with isotropic, single flux quantum vortices. Vortex locations are uncorrelated with strong scattering surface impurities, demonstrating bulk pinning. The vortex-induced sub-gap density of states fits an exponential decay from the vortex center, from which we extract a coherence length $\xi=27.6\pm 2.9 \text{\AA}$, corresponding to an upper critical field $H_{c2}=43 \text{T}$.Comment: 4 pages, 4 figure

Proceedings of the European MOOC stakeholder summit 2015

RESCIF is a French-speaking network with 14 faculties of technology from the North and from the South. One of their research themes is water and four partner institutions decided to build together a MOOC as tentative tool for disseminating knowledge and contribute to education of southern engineers. This MOOC “Rivers and Men” is thus an example of collaborative work. The paper gives some facts about the building process and the success of the course. Some reflections are proposed about the target and the actual audience and some preliminary conclusions are drawn about advantages and limitations of such collaborative approach

A Function of Nuclear Capability: India's Emergence as a Global Power

India is a growing economic, military, and technological force in the twenty-first century. It is now the fastest growing state in Asia, and subsequently increased its military budget, allowing for the development of better nuclear technology and capability. India’s recent geopolitical engagement includes attempting to establish relations with powerful neighboring China, establish itself as a global power, and continual tensions with Pakistan. These elements of economic and military development and geopolitical relations together create the conditions for India’s current rising geopolitical profile. Nuclear capability is a primary focus in twenty-first century international affairs, and through the primary lens and perspective of the theory of realism in international relations, I will analyze the ways in which the elements of India’s nuclear doctrine that delineate India’s resolve not to use nuclear weapons against non-nuclear states and its No First Use stance and amendments to this stance under major, biological, or chemical weapons attack aid India on its path to emergence as a key actor in international affairs

New AGNs discovered by H.E.S.S

During the last year, six new Active Galactic Nuclei (AGN) have been discovered and studied by H.E.S.S. at Very High Energies (VHE). Some of these recent discoveries have been made thanks to new enhanced analysis methods and are presented at this conference for the first time. The three blazars 1ES 0414+009, SHBL J001355.9-185406 and 1RXS J101015.9-311909 have been targeted for observation due to their high levels of radio and X-ray fluxes, while the Fermi/LAT catalogue of bright sources triggered the observation of PKS 0447-439 and AP Librae. Additionally, the BL Lac 1ES 1312-423 was discovered in the field-of-view (FoV) of Centaurus A thanks to the large exposure dedicated by H.E.S.S. to this particularly interesting source. The newly-discovered sources are presented here and in three companion presentations at this conference.Comment: 8 pages, 3 figures, proceeding from the 25th Texas Symposium on Relativistic Astrophysics (Heidelberg, Germany, 2010

Significant subsoil accumulation of mineral nitrogen under perennial crops in a ferralitic Amazonian upland soil: effects of land use systems and single-tree patterns.

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Water and nutrient flux measurements.

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Distribution of throughfall and stemflow in agroforestry, perennial monoculture, fallow and primary forest in the central Amazon, Brazil.

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SST-GATE: A dual mirror telescope for the Cherenkov Telescope Array

The Cherenkov Telescope Array (CTA) will be the world's first open observatory for very high energy gamma-rays. Around a hundred telescopes of different sizes will be used to detect the Cherenkov light that results from gamma-ray induced air showers in the atmosphere. Amongst them, a large number of Small Size Telescopes (SST), with a diameter of about 4 m, will assure an unprecedented coverage of the high energy end of the electromagnetic spectrum (above ~1TeV to beyond 100 TeV) and will open up a new window on the non-thermal sky. Several concepts for the SST design are currently being investigated with the aim of combining a large field of view (~9 degrees) with a good resolution of the shower images, as well as minimizing costs. These include a Davies-Cotton configuration with a Geiger-mode avalanche photodiode (GAPD) based camera, as pioneered by FACT, and a novel and as yet untested design based on the Schwarzschild-Couder configuration, which uses a secondary mirror to reduce the plate-scale and to allow for a wide field of view with a light-weight camera, e.g. using GAPDs or multi-anode photomultipliers. One objective of the GATE (Gamma-ray Telescope Elements) programme is to build one of the first Schwarzschild-Couder prototypes and to evaluate its performance. The construction of the SST-GATE prototype on the campus of the Paris Observatory in Meudon is under way. We report on the current status of the project and provide details of the opto-mechanical design of the prototype, the development of its control software, and simulations of its expected performance.Comment: In Proceedings of the 33rd International Cosmic Ray Conference (ICRC2013), Rio de Janeiro (Brazil). All CTA contributions at arXiv:1307.223

Fundamental Properties of the Highly Ionized Plasmas in the Milky Way

The cooling transition temperature gas in the interstellar medium (ISM), traced by the high ions, Si IV, C IV, N V, and O VI, helps to constrain the flow of energy from the hot ISM with T >10^6 K to the warm ISM with T< 2x10^4 K. We investigate the properties of this gas along the lines of sight to 38 stars in the Milky Way disk using 1.5-2.7 km/s resolution spectra of Si IV, C IV, and N V absorption from the Space Telescope Imaging Spectrograph (STIS), and 15 km/s resolution spectra of O VI absorption from the Far Ultraviolet Spectroscopic Explorer (FUSE). The absorption by Si IV and C IV exhibits broad and narrow components while only broad components are seen in N V and O VI. The narrow components imply gas with T<7x10^4 K and trace two distinct types of gas. The strong, saturated, and narrow Si IV and C IV components trace the gas associated with the vicinities of O-type stars and their supershells. The weaker narrow Si IV and C IV components trace gas in the general ISM that is photoionized by the EUV radiation from cooling hot gas or has radiatively cooled in a non-equilibrium manner from the transition temperature phase, but rarely the warm ionized medium (WIM) probed by Al III. The broad Si IV, C IV, N V, and O VI components trace collisionally ionized gas that is very likely undergoing a cooling transition from the hot ISM to the warm ISM. The cooling process possibly provides the regulation mechanism that produces N(C IV)/N(Si IV) = 3.9 +/- 1.9. The cooling process also produces absorption lines where the median and mean values of the line widths increase with the energy required to create the ion.Comment: Accepted for publication in the ApJ. Only this PDF file contains all the figures and tables in a single fil