Phonon-Coupled Electron Tunneling in Two and Three-Dimensional Tunneling Configurations

We treat a tunneling electron coupled to acoustical phonons through a realistic electron phonon interaction: deformation potential and piezoelectric, in two or three-dimensional tunneling configurations. Making use of slowness of the phonon system compared to electron tunneling, and using a Green function method for imaginary time, we are able to calculate the change in the transition probability due to the coupling to phonons. It is shown using standard renormalization procedure that, contrary to the one-dimensional case, second order perturbation theory is sufficient in order to treat the deformation potential coupling, which leads to a small correction to the transmission coefficient prefactor. In the case of piezoelectric coupling, which is found to be closely related to the piezoelectric polaron problem, vertex corrections need to be considered. Summing leading logarithmic terms, we show that the piezoelectric coupling leads to a significant change of the transmission coefficient.Comment: 17 pages, 4 figure

Polycystin-1 Surface Localization Is Stimulated by Polycystin-2 and Cleavage at the G Protein-coupled Receptor Proteolytic Site

The localization of polycystin (PC)1) to the plasma membrane requires coexpression with PC2 and cleavage at the PC1 G protein-coupled receptor proteolytic site. Neither the PC1 binding capacity of PC2 nor its channel function is required for this effect

Compact CdZnTe-based gamma camera for prostate cancer imaging

In this paper, we discuss the design of a compact gamma camera for high-resolution prostate cancer imaging using Cadmium Zinc Telluride (CdZnTe or CZT) radiation detectors. Prostate cancer is a common disease in men. Nowadays, a blood test measuring the level of prostate specific antigen (PSA) is widely used for screening for the disease in males over 50, followed by (ultrasound) imaging-guided biopsy. However, PSA tests have a high false-positive rate and ultrasound-guided biopsy has a high likelihood of missing small cancerous tissues. Commercial methods of nuclear medical imaging, e.g. PET and SPECT, can functionally image the organs, and potentially find cancer tissues at early stages, but their applications in diagnosing prostate cancer has been limited by the smallness of the prostate gland and the long working distance between the organ and the detectors comprising these imaging systems. CZT is a semiconductor material with wide band-gap and relatively high electron mobility, and thus can operate at room temperature without additional cooling. CZT detectors are photon-electron direct-conversion devices, thus offering high energy-resolution in detecting gamma rays, enabling energy-resolved imaging, and reducing the background of Compton-scattering events. In addition, CZT material has high stopping power for gamma rays; for medical imaging, a few-mm-thick CZT material provides adequate detection efficiency for many SPECT radiotracers. Because of these advantages, CZT detectors are becoming popular for several SPECT medical-imaging applications. Most recently, we designed a compact gamma camera using CZT detectors coupled to an application-specific-integrated-circuit (ASIC). This camera functions as a trans-rectal probe to image the prostate gland from a distance of only 1-5 cm, thus offering higher detection efficiency and higher spatial resolution. Hence, it potentially can detect prostate cancers at their early stages. The performance tests of this camera have been completed. The results show better than 6-mm resolution at a distance of 1 cm. Details of the test results are discussed in this paper

CMS physics technical design report : Addendum on high density QCD with heavy ions

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