21 research outputs found
Factors related to perceived needs of primary caregivers of patients with schizophrenia
- Author
- Publication venue
- Asia University
- Publication date
- Field of study
[[abstract]]Background/Purpose: Schizophrenia is a chronic mental illness, and sufferers are usually dependent on family, primary caregivers in particular. The present study was designed to assess the perceived needs of caregivers so that adequate services can be provided for them in the community.
Methods: A total of 177 primary caregivers were interviewed with the structured burden-and-need schedules to determine their perceived needs, and the related clinical and demographic factors. Four-teen perceived needs were identified and classified into different need clusters using the generalized association plots. A multiple regression of logistic model was adopted to explore the relationships between the related factors and perceived needs.
Results: Four clusters of perceived needs were identified, which included assistant patient care (77.6%), access to relevant information (66.1%), societal support (68.2%), and burden release (27.2%). These needs were significantly related to number of admissions, duration of illness, relationship between caregiver and patient, and education level of the caregiver.
Conclusion: Four clusters of caregivers' perceived needs were identified and found to be related to psychopathologic and demographic factors. These data are of value in designing appropriate community psychiatric programs to improve the quality of care and enhance the capacity of primary caregivers to care for patients
Cancer Biomarker Discovery: The Entropic Hallmark
- Author
- A Alcaraz
- A Arabzadeh
- A Bagri
- A Balbin
- A Bantis
- A Ben-Naim
- A Bolander
- A Buhmeida
- A Burykin
- A Chetcuti
- A de Baey
- A Efeyan
- A Eroglu
- A Fabarius
- A Forget
- A Fujita
- A Geirsson
- A Geirsson
- A Geirsson
- A Guffanti
- A Hugel
- A Inoue
- A Isidoro
- A Jang
- A Kollara
- A Kuzmanov
- A Lundqvist
- A Maria McCrohan
- A Marreiros
- A Mendes
- A Mitra
- A Nassar
- A Petitjean
- A Petitjean
- A Pinzon-Charry
- A Richmond
- A Roesch
- A Santinelli
- A Schmidt
- A Shapiro
- A Sreekumar
- A Takeno
- A Urbanucci
- A Winter
- A Yemelyanov
- AA Babiker
- AA Babiker
- AA Tarhini
- AC Dudley
- AD Judge
- AD Ortega
- AG Puebla-Mora
- AH Fox
- AH Fox
- AI Riker
- AJ Liu
- AK Meeker
- AK Panigrahi
- AK Witkiewicz
- AL Cheung
- AL Fachin
- AL Gartel
- AL Okorokov
- AM Craig
- AM Lena
- AM Levin
- AM Tokes
- AP South
- AS Payne
- AS Verkman
- AS Verkman
- AS Verkman
- AS Wierzbicki
- AV Skamrov
- AW Maniccia
- B Cinar
- B Gao
- B Ouyang
- B Ren
- B Ryu
- B Tycko
- B Vukovic
- B Wu
- B Wu
- BD Dimitrov
- BF Gilmore
- BF Goncalves
- BF Skinnider
- BK Zehentner
- BL Adamsen
- BL de Groot
- BR Johnson
- BR Middleman
- BS Strauss
- C Adami
- C Bastide
- C Cao
- C Cybulski
- C Haqq
- C Hayashi
- C Hornig
- C Ivorra
- C Kumar-Sinha
- C Langner
- C Magi-Galluzzi
- C Magi-Galluzzi
- C Muller-Tidow
- C Nessler-Menardi
- C Nunez
- C Pequeux
- C Rajesh
- C Xu
- C Yuli
- CD Sturgis
- CD Truong
- CG Pham
- CG Rogers
- CG Rogers
- CJ Hutchison
- CJ Pronk
- CK Mavis
- CL Stewart
- CL Wu
- CM Caves
- CM Caves
- CM Clemson
- CM Perou
- CP Gray
- CP Gray
- CP Gray
- CR Mangahas
- CS Bond
- D Acehan
- D Bonn
- D Denhardt
- D Fu
- D Gilley
- D Gisselsson
- D Hanahan
- D Javelaud
- D Kroepfl
- D Lodygin
- D Maraldo
- D Ouazia
- D Scadden
- D Wang
- D Wang
- D Wang
- D Weckermann
- D Wodarz
- DA Shoskes
- DA Tennant
- DE Hansel
- DF Gleason
- DG Albertson
- DG Tenen
- DH Palmer
- DJ Darley
- DJ Grignon
- DJ Smit
- DJ Son
- DJ Wong
- DJC MacKay
- DK Koynova
- DK Lee
- DM Kube
- DM Peehl
- DR Wonsey
- DS Perez
- DV Makarov
- DV Makarov
- E Beitz
- E Beitz
- E Cabuy
- E Fagiani
- E Flannery
- E Geissinger
- E Kikuchi
- E Kruse
- E Sbisa
- E Sprecher
- E Tajkhorshid
- EA Ostrander
- EH Feng
- EH Feng
- EM Rosen
- EM Rosen
- EM Schaeffer
- EO Kehinde
- ET Canepa
- EV Vykhovanets
- EY Lin
- EY Tan
- F Bai
- F Bonetto
- F Boralevi
- F Buback
- F Colotta
- F Langer
- F Saad
- F Tas
- F Yang
- FS Krause
- G Benga
- G Bhanot
- G Blandino
- G Buchanan
- G Kaic
- G Kristiansen
- G Kristiansen
- G Kroemer
- G Murugaiyan
- G Petrovics
- G Pirtskhalaishvili
- G Russo
- G Sardana
- G Stirling
- G Tscheudschilsuren
- G Untergasser
- G Venkataraman
- G von Figura
- GA Jarvis
- GE Crooks
- GF Azzone
- GF Ding
- GL Shen-Ong
- GP Bienert
- GQ Daley
- GR Ribeiro
- GS Palapattu
- GV Glinsky
- GV Glinsky
- H Chang-zheng
- H Chen
- H Dzojic
- H Gronberg
- H Haghnegahdar
- H Harant
- H Harlin
- H Kida
- H Li
- H Liu
- H Miyake
- H Nemoto
- H Ostrer
- H Pilch
- H Rangaswami
- H Rangaswami
- H Rangaswami
- H Ren
- H Roca
- H Roca
- H Samaratunga
- H Savli
- H Schlechte
- H Schoder
- H Sheng
- H Sunwoo
- H Then
- H Wang
- H Wang
- HC Lee
- HG Thomas
- HJ Worman
- HL Winfield
- HS Leff
- HT Quan
- HY Vu
- HZ Zhang
- I Agalliu
- I Bae
- I Ben-Porath
- I Grosse
- I Haritoglou
- I Leav
- I Marinescu
- I Moll
- I Sakai
- IE Wertz
- IK Lim
- IL Tourkova
- IM Bachmann
- IM Shih
- IW Reiniger
- IY Dodin
- J Bartkova
- J Edwards
- J Fellenberg
- J Gille
- J Graells
- J Jaeger
- J Johnson
- J Lammerding
- J Laoukili
- J Lapointe
- J Linden
- J Luo
- J Luo
- J Luo
- J Mandelin
- J Melamed
- J Moser
- J Rangel
- J Rapley
- J Reimand
- J Ruiz-Ederra
- J Schmitz
- J Schultz
- J Soikkeli
- J Stewart
- J Suh
- J Walter-Yohrling
- J Wang
- J Wang
- J Weiske
- J Xu
- J Yang
- J Yang
- J Zheng
- JA Camargo
- JA Douglas
- JA Hackett
- JA Karam
- JA McGrath
- JA McGrath
- JA McGrath
- JA McGrath
- JA Mobley
- JA Pettus
- JB Roche
- JC Cheville
- JD French
- JD Licchesi
- JD Owen
- JE Lai-Cheong
- JE Sleeman
- JE Wilusz
- JG Wen
- JH Lee
- JH Luo
- JJ Brey
- JJ Park
- JJ Raffoul
- JJ Tseng
- JJ Van den Oord
- JK Wahl 3rd
- JL Broers
- JL Herrmann
- JL Phillips
- JM Brandner
- JM Bridger
- JM Cummins
- JM Gonzalez
- JM Lizcano
- JM Muller
- JM Muller
- JM Parrondo
- JM Saffin
- JN Hutchinson
- JN Mubiru
- JN Mubiru
- JN Mubiru
- JP Arbitrario
- JP Clark
- JP Ehlers
- JP Fruehauf
- JP Struewing
- JR Cansino Alcaide
- JR McMillan
- JS Butler
- JS Butler
- JS Fang
- JS Hub
- JS Lee
- JS Mattick
- JS Mattick
- JS Mattick
- JT Bishoff
- JT Chang
- JW Denham
- K Armstrong
- K Fujita
- K Ishibashi
- K Ishitani
- K Kami
- K Kasuno
- K Kumagai
- K Mizutani
- K Namiki
- K Ruan
- K Ruan
- K Shilo
- K Sircar
- K Suzuki
- K Swisshelm
- K Takahara
- K Tani
- K Tokunaga
- K Tomkova
- K Trpkov
- K Yamada
- KA Tasken
- KA Zuhlke
- KH Hoffmann
- KH Tsui
- KL Nastiuk
- KL Simpson
- KL van Golen
- KN Ekdahl
- KP Porkka
- KR Ghani
- KV Prasanth
- L Capparuccia
- L Carlsson
- L Cheng
- L de Meis
- L Galluzzi
- L Kneisel
- L Lessard
- L Li
- L Moro
- L Moro
- L O'Regan
- L Packer
- L Pasini
- L True
- L Verdoucq
- L Verschooten
- L Xu
- L Zheng
- LA Diaz-Martinez
- LB Mora
- LE Clarke
- LE Finlan
- LF Brown
- LF Zerbini
- LL Chen
- LL Smith
- LL Smith
- LM Godsel
- LP Kunju
- M Aalamian-Matheis
- M Aghaei
- M Bakhanashvili
- M Boury-Jamot
- M Boury-Jamot
- M Buxade
- M Chellaiah
- M Cimitan
- M Craig
- M Dumas
- M Dundr
- M Esteller
- M Estler
- M Fabbri
- M Fukunaga-Kalabis
- M Fukunaga-Kalabis
- M Furuno
- M Gilbert
- M Hara-Chikuma
- M Hara-Chikuma
- M Hara-Chikuma
- M Hara-Chikuma
- M Hatzfeld
- M Hatzfeld
- M Heenen
- M Ismail
- M Karaivanov
- M Kashani-Sabet
- M Kato
- M Katoh
- M Kinoshita
- M Korabiowska
- M Kulesz-Martin
- M Lei
- M Lisovsky
- M Marko
- M Mellado
- M Mishima
- M Mockenhaupt
- M Moghaddami
- M Moghaddami
- M Nessling
- M Olsson
- M Onaitis
- M Parisi
- M Schostak
- M Tischkowitz
- M Traka
- M Tribus
- M Varma
- M Venoux
- M Watanabe
- M Yang
- M Yasui
- M Zhou
- M Zhou
- M Zhou
- MA Castro
- MA Chekmareva
- MA Chellaiah
- MA Ficazzola
- MA Halsey
- MA Roder
- MA Rubin
- MA Rubin
- MA Rubin
- MB Martens
- MB Rettig
- MC Caino
- MC Schumacher
- MD Desrosiers
- MD Duff
- MD Lloyd
- ME Blank
- ME Grossmann
- ME Grossmann
- ME Laski
- ME Morrison
- MF Fraga
- MH Vaarala
- MK Thomsen
- MK Thomsen
- MM Petrovic
- MM Rashid
- MR Rosner
- MS O'Connor
- MS Tretiakova
- MT Kalcioglu
- MT Ling
- MT Martin
- MT Sung
- MV Blagosklonny
- MY Lee
- N Bahamontes-Rosa
- N Donin
- N Konishi
- N Lapteva
- N Maeda
- N Nadiminty
- N Rabiau
- N Singh
- NG Hussein
- NI Andreyev
- NJ Fisch
- NV Whittock
- NV Whittock
- O Bettendorf
- O Canbolat
- O Itzhaki
- O Kwon
- OA Rosso
- OW Rokhlin
- P Agre
- P Agre
- P Agre
- P Agre
- P Allavena
- P Berthon
- P Boukamp
- P Cossu-Rocca
- P Dhawan
- P Dhawan
- P Duesberg
- P Duesberg
- P Duesberg
- P Hainaut
- P Ji
- P Karakiewicz
- P Koivisto
- P Roy-Burman
- P Rustin
- P Sini
- P Slijepcevic
- P Sotomayor
- P Sotomayor
- P Steigemann
- P Zhang
- Pablo Moscato
- PD Walden
- PG Gallagher
- PH Gumerlock
- PH Konig
- PI Nedvetsky
- PJ Gray Jr
- PJ Zielie
- PL Chang
- PM Lacal
- PM Lacal
- PM Mordaka
- PM Steijlen
- PT Landsberg
- PT Went
- PU Malmstrom
- PW Kuchel
- PW Lamberti
- Q Lu
- Q Zhou
- R Agarwal
- R Berretta
- R Birnie
- R Bordoni
- R Casalini
- R Das
- R Dobson
- R Halaban
- R Horuk
- R Klimek
- R Klimek
- R Kuefer
- R Lin
- R Mazzucchelli
- R Mukherjee
- R Radosavljevic
- R Rai
- R Sougrat
- RA Craven
- RA Hegele
- RA Sturm
- RA Weinberg
- RC Lee
- RD Ballal
- RD Loberg
- RD Loberg
- RD Loberg
- RD Loberg
- Regina Berretta
- RG Uzzo
- RJ Jin
- RJ Urban
- RJ Webster
- RL Boguslavsky
- RL Shattuck
- RMH Lopez-Ruiz
- RP Ciavarra
- RP Ciavarra
- RP Singh
- RS Weinstein
- RT Nitta
- RW DeVere White
- S Ashida
- S Brychtova
- S Cardinale
- S Das
- S Das
- S Dettwiler
- S Di Cesare
- S Doratiotto
- S Ersoy-Evans
- S Fan
- S Gagos
- S Ghosh
- S Gunia
- S Hanada
- S Hauptmann
- S Hiratsuka
- S Horsburgh
- S Huerta-Yepez
- S Jhavar
- S Jhavar
- S Kuwahara
- S Kyle
- S Landreville
- S Makovets
- S Morohashi
- S Olgac
- S Philip
- S Philip
- S Prislei
- S Rankin
- S Rankin
- S Satoh
- S Sur
- S Takahashi
- S Takahashi
- S Tancharoen
- S Verdier-Sevrain
- S Yeh
- S Zha
- S Zha
- S Zha
- SA Narod
- SH Lin
- SJ Yeung
- SK Kang
- SL Kong
- SL Zheng
- SM Edwards
- SM Ho
- SM Saparov
- SQ Xie
- SR Alonso
- SS Kadkol
- SV Setzer
- T Dalmay
- T Drewa
- T Hoevel
- T Ishiyama
- T Jamaspishvili
- T Kusumi
- T Litman
- T Ma
- T Mirtti
- T Murakami
- T Oyama
- T Schlomm
- T Schlomm
- T Sheridan
- T Shimizu
- T Sobolik-Delmaire
- T Sun
- T Takahashi
- T Takeda
- T Thornburg
- T Watanabe
- T Yu
- TB Lewis
- TD Prickett
- TH Ecke
- TJ McDonnell
- TJ Park
- TL Schmit
- TL Schmit
- TO Nielsen
- TR Mercer
- U Brinck
- U Graeven
- U Gruneberg
- UV Wesley
- V Ambros
- V Barak
- V Fradet
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Molinie
- V Pekovic
- V Rajaram
- V Samanna
- V Wessagowit
- V Winnepenninckx
- VD Acevedo
- VK Vanguri
- VL Verstraeten
- W Chen
- W Cosme-Blanco
- W Gade
- W Ritchie
- W Spirkl
- W Tettelbach
- W Wang
- W Weichert
- W Weichert
- W Weichert
- WB Isaacs
- WD Dunsmuir
- WE Naugler
- William C. S. Cho
- WK Kaufmann
- WK Lee
- X Chen
- X Cheng
- X Dong
- X Dong
- X Huang
- X Li
- X Liu
- X Liu
- X Meng
- X Ouyang
- X Tang
- X Wu
- X Zhang
- XJ Yang
- XQ Wang
- Y Bu
- Y Cai
- Y Deng
- Y Ito
- Y Katagiri
- Y Kozuka
- Y Lai
- Y Liu
- Y Lu
- Y Lu
- Y Ohyama
- Y Shav-Tal
- Y Sugiyama
- Y Sun
- Y Wang
- Y Wang
- Y Wu
- Y Yamamoto
- Y Yang
- Y Zhou
- YB Lim
- YC Chao
- YJ Ko
- YL Liu
- YN Liu
- YT Sasaki
- YT Sasaki
- YU Katagiri
- Z Jiang
- Z Jiang
- Z Jiang
- Z Jiang
- Z Jiang
- Z Rudzki
- ZA Dotan
- ZR Yurkovetsky
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Background: It is a commonly accepted belief that cancer cells modify their transcriptional state during the progression of the disease. We propose that the progression of cancer cells towards malignant phenotypes can be efficiently tracked using high-throughput technologies that follow the gradual changes observed in the gene expression profiles by employing Shannon's mathematical theory of communication. Methods based on Information Theory can then quantify the divergence of cancer cells' transcriptional profiles from those of normally appearing cells of the originating tissues. The relevance of the proposed methods can be evaluated using microarray datasets available in the public domain but the method is in principle applicable to other high-throughput methods. Methodology/Principal Findings: Using melanoma and prostate cancer datasets we illustrate how it is possible to employ Shannon Entropy and the Jensen-Shannon divergence to trace the transcriptional changes progression of the disease. We establish how the variations of these two measures correlate with established biomarkers of cancer progression. The Information Theory measures allow us to identify novel biomarkers for both progressive and relatively more sudden transcriptional changes leading to malignant phenotypes. At the same time, the methodology was able to validate a large number of genes and processes that seem to be implicated in the progression of melanoma and prostate cancer. Conclusions/Significance: We thus present a quantitative guiding rule, a new unifying hallmark of cancer: the cancer cell's transcriptome changes lead to measurable observed transitions of Normalized Shannon Entropy values (as measured by high-throughput technologies). At the same time, tumor cells increment their divergence from the normal tissue profile increasing their disorder via creation of states that we might not directly measure. This unifying hallmark allows, via the the Jensen-Shannon divergence, to identify the arrow of time of the processes from the gene expression profiles, and helps to map the phenotypical and molecular hallmarks of specific cancer subtypes. The deep mathematical basis of the approach allows us to suggest that this principle is, hopefully, of general applicability for other diseases
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
- Ab Majid MA
- Ab Rahman AS
- Ab Rahman R
- Abayasinghe C
- Abbott T
- Abdullah NH
- Abdur-Rahman L
- Abeloos J
- Abernethy C
- Abidin UN
- Abrunhosa A
- Absar M
- Adam S
- Adams D
- Adams G
- Adamson M
- Adekola O
- Adelaja Y
- Ademola A
- Adenekan A
- Adenike O
- Adeolu AA
- Adetoye A
- Adewale B
- Adigun T
- Adolfsson A
- Aflori L
- Africander C
- Afshari A
- Agarwal V
- Agodirin O
- Aguero Vera M
- Aguzzoli C
- Ahmad A
- Ahmad N
- Ahmad T
- Ahmad T
- Ahmad Y
- Ahmed A
- Ahmed J
- Ai Y
- Aignatoaie M
- Aimoniotou-Georgiou E
- Akanmu O
- Akerman N
- Akinwale M
- Akring I
- Al 'Amri K
- Al Anizi M
- Al hussaini S
- Al-Soudaine Y
- Aladin H
- Alagbe-Briggs O
- Alaman Laguarda G
- Albaj S
- Alcock D
- Alcock L
- Aldecoa C
- Aldecoa C
- Aleixo FB
- Alexander H
- Alexander M
- Alexander-Sefre F
- Alherz F
- Ali H
- Ali M
- Ali S
- Alias A
- Alias AH
- Alias RLR
- Alit MA
- Allen S
- Allen SJ
- Allison J
- Alloj C
- Allorto NL
- Allsop J
- Almeida W
- Alonso E
- Alphonsus C
- Alvares D
- Alves MJ
- Amador JCB
- Ameer Y
- Amendola CP
- Ami N
- Amstrup-Hansen L
- Anagnou A
- Andersen C
- Anderson C
- Anderson C
- Anderson F
- Anderson P
- Andreadaki E
- Andreou A
- Andreou P
- Andrew A
- Andrews E
- Angermair S
- Angus K
- Anillo V
- Antal O
- Antill P
- Antoniadou E
- Antonina W
- Apagaki E
- Apostolou K
- Applewhaite C
- Aquino LPG
- Ar P
- Arawwawala D
- Ardern D
- Argue R
- Arkalaki E
- Armaganidis A
- Armstrong J
- Armstrong R
- Arnaoutoglou C
- Arnaoutoglou E
- Arnold G
- Arrandale L
- Arrich J
- Arrigo M
- Arshad H
- Arshad MA
- Arumugam S
- Arustei M
- Arvaniti K
- Arya A
- Arya S
- Asimakos A
- Asudo F
- Athanasakis E
- Atiku M
- Attrill E
- Attwood C
- Auer P
- Avidan M
- Avila Sanchez FJ
- Avila EJD
- Avis J
- Awad H
- Axioti E
- Ayyaz H
- Azam UAA
- Azambuja P
- Azevedo C
- Aziz FZ
- Baas P
- Baghirzada L
- Bai H-P
- Bai Y
- Baillie S
- Baines D
- Baio TH
- Bairaktari A
- Baker G
- Baker K-A
- Baker P
- Balain B
- Balaji P
- Balajonda N
- Balanescu A
- Balasubramaniam M
- Baldisserotto S
- Baldwin J
- Baldwin M
- Balfoussia D
- Bali C
- Bandeira ME
- Banerjee R
- Bankewitz C
- Banner-Goodspeed V
- Bao Q
- Barcraft-Barnes H
- Barneto L
- Barnett A
- Baroselli A
- Barraclough J
- Barras J-P
- Barrett S
- Barrett WJ
- Basanth S
- Batchelor N
- Bateman B
- Bates A
- Bates S
- Batista HD
- Bauchmuller K
- Bauer M
- Baumgarten G
- Baxter L
- Beaton C
- Beattie S
- Beavis V
- Bechan S
- Bejia T
- Belciu I
- Belda MT
- Bell G
- Bell R
- Bell S
- Bellandi M
- Bello J
- Beloeil H
- Belskiy V
- Ben-Menachem E
- Benavent P
- Benevento A
- Bengeri S
- Bennett C
- Bennett M
- Bennett R
- Bennett V
- Bentley C
- Beretta L
- Berg A
- Bergin C
- Bernard A
- Berntsen E
- Bertram W
- Bester D
- Bester M
- Bettega F
- Bettinelli A
- Bhardwaj N
- Bhatia K
- Bhula C
- Bi Y
- Biais M
- Biccard BM
- Bidd H
- Bidgoli J
- Biffen A
- Bignami E
- Bilolikar A
- Bin Mustapha MT
- Birch J
- Bishop DG
- Biyase T
- Bizios C
- Blackwell C
- Blackwood D
- Blaj M
- Blakemore SP
- Bland M
- Blunt M
- Blyth K
- Bocchino S
- Bodansky D
- Bodger P
- Boer C
- Boereboom C
- Boggiano V
- Bogner G
- Bolaji B
- Bolton D
- Boone M
- Boschi L
- Boshier P
- Botes M
- Botis I
- Bottini C
- Bottrill F
- Bouchez S
- Boulton K
- Bouris V
- Bourner L
- Boutsikos G
- Bouwman A
- Bouwman RA
- Bowrey S
- Boxall L
- Boyd C
- Bradburn M
- Bradley J
- Branagan G
- Branco T
- Brand B
- Brandsborg B
- Breitenstein S
- Brennan A
- Brennan E
- Brenner L
- Brincat M
- Briscoe R
- Bristogiannis S
- Brooke J
- Brookes J
- Brookes M
- Brooks C
- Broomby R
- Brotto AF
- Brown A
- Brown CW
- Brown G
- Brown J
- Brown J
- Brown L
- Brown R
- Brown R
- Browning J
- Bruma D
- Brunete T
- Brunswicker A
- Bryant H
- Bua E
- Buccimazza I
- Buckley S
- Buerkle C
- Buhre W
- Buhre W
- Buhrer T
- Builu PM
- Buise M
- Bullock C
- Bunwarie B
- Burns K
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- Zonneveldt H
- Zou X
- Zoulamoglou M
- Zsisku L
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain A.
- Ajith Parameswaran
- Akutsu Tomotada
- Albanesi S.
- Alfaidi R. A.
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Amato Alex
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Arif Shaikh Md
- Aritomi Naoki
- Arnaud Nicolas
- Arogeti M.
- Aronson S. M.
- Arène M.
- Asada Hideki
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Aubin Florian
- Babak Stanislav
- Badaracco Francesca
- Badger C.
- Bae S.
- Bae Y.
- Bagnasco Stefano
- Bai Y.
- Baier J. G.
- Baird J.
- Bajpai Rishabh
- Baka T.
- Ball M.
- Ballardin G.
- Ballmer S. W.
- Baltus Grégory
- Banagiri Sharan
- Banerjee Biswajit
- Bankar Deepak
- Barayoga J. C.
- Barish B. C.
- Barker D.
- Barneo Pablo
- Barone Fabrizio
- Barr Bryan
- Barsotti Lisa
- Barsuglia Matteo
- Barta Dániel
- Bartlett J.
- Barton Mark Andrew
- Bartos I.
- Basak S.
- Bassiri Riccardo
- Basti A.
- Bawaj Mateusz
- Bayley Joseph
- Bazzan M.
- Beatrice Cummings Rebecca
- Bedakihale V. M.
- Beirnaert Freija
- Bejger Michał
- Belahcene I.
- Bell Angus
- Benedetto V.
- Beniwal D.
- Benoit William
- Bentley Joe
- BenYaala M.
- Bera S.
- Berbel Marina
- Bergamin F.
- Berger Beverly
- Bernuzzi Sebastiano
- Beroiz Martin
- Berry Christopher P. L.
- Bersanetti Diego
- Bertolini A.
- Betzwieser Joseph
- Beveridge Damon
- Bhandare R.
- Bhandari A. V.
- Bhardwaj Uddipta
- Bhatt R.
- Bhattacharjee Dripta
- Bhaumik Shubhagata
- Bianchi A.
- Bilenko I. A.
- Bilicki Maciej
- Billingsley GariLynn
- Bini S.
- Birnholtz Ofek
- Biscans S.
- Bischi M.
- Bisht A.
- Biswas Bhaskar
- Bitossi M.
- Blackburn Kent
- Blair C. D.
- Blair D. G.
- Blair R. M.
- Bobba F.
- Bode Nina
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- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 王谨
- 都丸 隆行
- Publication venue
- Publication date
- 01/04/2023
- Field of study
Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects
Accuracy versus precision in boosted top tagging with the ATLAS detector
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- Aakvaag E
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- Da Fonseca Pinto JV
- Da Silva GG
- Da Via C
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- De Carvalho ALM
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- De Regie JBDV
- de Renstrom PAB
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- Dumitriu AE
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- Zhemchugov A
- Zheng J
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- Zhong D
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- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- IOP Publishing
- Publication date
- 01/08/2024
- Field of study
Abstract
The identification of top quark decays where the top quark has a large momentum transverse to the beam axis, known as top tagging, is a crucial component in many measurements of Standard Model processes and searches for beyond the Standard Model physics at the Large Hadron Collider.
Machine learning techniques have improved the performance of top tagging algorithms, but the size of the systematic uncertainties for all proposed algorithms has not been systematically studied.
This paper presents the performance of several machine learning based top tagging algorithms on a dataset constructed from simulated proton-proton collision events measured with the ATLAS detector at √
s
= 13 TeV.
The systematic uncertainties associated with these algorithms are estimated through an approximate procedure that is not meant to be used in a physics analysis, but is appropriate for the level of precision required for this study.
The most performant algorithms are found to have the largest uncertainties, motivating the development of methods to reduce these uncertainties without compromising performance.
To enable such efforts in the wider scientific community, the datasets used in this paper are made publicly available.</jats:p
Needs and Demands for Community Psychiatric Rehabilitation Programs from the Perspectives of Patients and Caregivers
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Patient- and treatment-related risk factors associated with neck muscle spasm in nasopharyngeal carcinoma patients after intensity-modulated radiotherapy
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Utilization of dental care among patients with severe mental illness: a study of a National Health Insurance database
- Author
- A Abbott
- A Azarpazhooh
- A Khocht
- A Mago
- AA Bahekar
- AH Friedlander
- AH Friedlander
- AH Friedlander
- B Hede
- B Hede
- B Molendijk
- C Hilton
- CD Mueller
- CM Chang
- CR Farnam
- D Locker
- DJ Stiefel
- E Jackson
- E Velasco
- F Scheutz
- FB Dickerson
- H Syrjälä A-M
- H Syrjälä A-M
- I Mirza
- IF Angelillo
- IL Chapple
- J Nielsen
- J Sheridan
- JM Chalmers
- K Persson
- KH Lee
- KY Chu
- Ling-Ling Yeh
- LJ Heaton
- LL Humphrey
- M Dawkes
- Miao-Jean Lin
- MP Cullinan
- MW Woolfolk
- O Gurbuz
- Po-Ren Teng
- PR Teng
- R Patel
- RC Williams
- RG McCreadie
- RJ Manski
- RP Roca
- S Kisely
- T Janardhanan
- T Ramon
- V Bertaud-Gounot
- V Pohjola
- WA Shultis
- Y Qiu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Correlation of cumulus gene expression of GJA1, PRSS35, PTX3, and SERPINE2 with oocyte maturation, fertilization, and embryo development
- Author
- A Salustri
- AM Simon
- AP Montfoort van
- CH Lu
- Chung-Hao Lu
- D Loutradis
- F Cillo
- G Leonardsson
- GM Kidder
- H Diao
- HX Wang
- I Edry
- J Ekart
- J Hasegawa
- JJ Eppig
- KJ Livak
- KM Gebhardt
- Ling-Yu Yeh
- LJ McKenzie
- LL Veeck
- LM Gui
- M Hamel
- M Hamel
- M Yokoo
- MC Scholtes
- Ming-Huei Lin
- MJ Carabatsos
- MM Matzuk
- P Feuerstein
- P Feuerstein
- P Wahlberg
- R Devjak
- RA Anderson
- Robert Kuo-Kuang Lee
- S Assou
- S Varani
- S Wathlet
- S Wathlet
- Sheng-Hsiang Li
- T Burnik Papler
- TY Li
- WJ Yang
- X Zhang
- Ying-Jie Chen
- YQ Su
- Yuh-Ming Hwu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Toxicological effect of TiO2 nanoparticle-induced myocarditis in mice
- Author
- A Nakagomi
- A Seaton
- A Seaton
- B Li
- B Li
- B Wang
- BW Seymour
- C Lang
- D Xiong
- DB Warheit
- ETH Yeh
- F Amiri
- Fashui Hong
- G Kania
- G Oberdörster
- HH Wang
- HT Liu
- IS Anand
- J Rengarajan
- J Wei
- JG Li
- JH Schefe
- JH Shannahan
- Jie Hong
- JJ Wang
- JL Alonso-Martinez
- JL Kang
- JR Teerlink
- JS Kim
- JT Willerson
- JZ Zhao
- JZ Zhao
- KM Murphy
- L Ding
- L Mikkelsen
- L Sheng
- Lei Sheng
- Ling Wang
- LL Ma
- LM Faddah
- M Bujak
- M Nimata
- MB Sporn
- N Paolocci
- NIOSH
- NL Mills
- NL Tsakadze
- P Yang
- PM Ridker
- PO Bonetti
- PV AshaRani
- R Baan
- RD Brook
- RJ Delfino
- RK Li
- RM Mroz
- RP Hu
- S Malek
- S Verma
- SA Bustin
- SG Han
- SJ Szabo
- SJ Szabo
- SM Dunlay
- SS Palaniyandi
- TA Pearson
- VV Patrov
- W Roberts
- W Wojakowski
- WG Kreyling
- XH Yu
- Xiaohong Yu
- Y Huo
- Y Morimoto
- YG Ze
- Yingjun Zhou
- ZQ Yan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study