Can MRI related patient anxiety be prevented?

Purpose: To evaluate the effectivity of a combined intervention of information and communication to reduce magnetic resonance imaging (MRI) anxiety using prolactin and cortisol as biochemical markers and State Trait Anxiety Inventory (STAI)

Multistage dolomitization in Late Jurassic-Early Cretaceous platform carbonates (Berdiga Formation), Basoba Yayla (Trabzon), NE Turkey: Implications of the generation of magmatic arc on dolomitization

KANDEMIR, RAIF/0000-0002-0344-9159; Ozyurt, Merve/0000-0003-1596-5916WOS: 000418971300001Late Jurassic-Early Cretaceous Berdiga Formation, which is widely distributed in an E-W trending belt in the Eastern Pontides (NE Turkey), is composed of platform carbonates. the formation shows varying lithofacies changing from supratidal to platform margin reef both laterally and vertically. the studied Baioba Yayla (Trabzon, NE Turkey) area comprises one of the typical exposures of formation in the northern zone of Eastern Pontides. in this area, the lower parts of the formation are pervasively dolomitized by fabric-destructive and fabric-preserving replacive dolomites that are Ca rich and nonstoichiometric (Ca56-60Mg40-44). Replacement dolomites (Rd) are represented by delta O-18 values of -15.3 to -4.2 (VPDB), delta C-13 values of -3.7-1.5 parts per thousand (VPDB), and Sr-87/Sr-86 ratios of 0.70675-0.70731. Petrographic and geochemical evidence implies that Rd dolomites are formed before compaction at shallow-moderate burial depths from Late Jurassic-Early Cretaceous seawater and/or partly modified seawater as a consequence of rock/water interaction, and they are recrystallized at elevated temperatures during subsequent burial. During subsequent Late Cretaceous diagenetic process when the region became a magmatic arc, Rd1a and Rd3 dolomite were recrystallized by hydrothermal fluids of marine origin. the dolomite cements (Cd) overlying the low-amplitude stylolites have similar geochemical charasteristics than Rd1a and Rd3 dolomite and are characterized by high homogenization temperatures (Th). This might indicate that Cd dolomite was precipitated from hydrothermal fluids of marine origin that recrystallized the Rd1a and Rd3 dolomite. the fact that Cd dolomite comprising the latest phase of dolomitization is overlain by coarsely crystalline mosaic calcite and silica cements may indicate that diagenetic fluids were undersaturated with respect to dolomite and oversaturated with respect to calcite and silica.Scientific Research Unit of the Karadeniz Technical University [8400]This study was financially supported by the Scientific Research Unit of the Karadeniz Technical University under contract no 8400. the appreciation is extended to Dr. Emin Ciftci (Istanbul Technical University) for his help for microscopic studies

Lidocaine treatment in pediatric convulsive status epilepticus

Backgound: Convulsive status epilepticus (CSE) may end fatally or leave serious sequelae. CSE treatment, invariably an emergency case, is based upon i.v. benzodiazepines as well as phenytoin, barbiturates or both. The present paper reports efficiency of lidocaine in CSE

COVID-19 Disease in Presenting to the Pediatric Emergency Department: A Multicenter Study of 8886 Cases.

Background: The aim was to evaluate the epidemiological, clinical, laboratory, and radiologic data of children with SARS-CoV-2 positivity by polymerase chain reaction (PCR) together with treatment strategies and clinical out-comes and to evaluate cases of multisystem inflammatory syndrome in children (MIS-C) in this population.Methods: This was a multicenter retrospective observational cohort study performed in the pediatric emergency departments of 19 tertiary hospitals. From March 11, 2020, to May 31, 2021, children who were diagnosed with confirmed nasopharyngeal/tracheal specimen SARS-CoV-2 PCR positivity or positivity for serum-specific anti-bodies against SARS-CoV-2 were included. Demographics, presence of chronic illness, symptoms, history of con-tact with SARS-CoV-2 PCR-positive individuals, laboratory and radiologic investigations, clinical severity, hospital admissions, and prognosis were recorded.Results: A total of 8886 cases were included. While 8799 (99.0%) cases resulted in a diagnosis of SARS-CoV-2 with PCR positivity, 87 (1.0%) patients were diagnosed with MIS-C. Among SARS-CoV-2 PCR-positive patients, 51.0% were male and 8.5% had chronic illnesses. The median age was 11.6 years (IQR: 5.0-15.4) and 737 (8.4%) patients were aged <1 year. Of the patients, 15.5% were asymptomatic. The most common symptoms were fever (48.5%) and cough (30.7%) for all age groups. There was a decrease in the rate of fever as age increased (p < 0.001); the most common age group for this symptom was <1 year with the rate of 69.6%. There was known contact with a SARS-CoV-2 PCR-positive individual in 67.3% of the cases, with household contacts in 71.3% of those cases. In terms of clinical severity, 83 (0.9%) patients were in the severe-critical group. There was hospital admission in 1269 (14.4%) cases, with 106 (1.2%) of those patients being admitted to the pediatric intensive care unit (PICU). Among patients with MIS-C, 60.9% were male and the median age was 6.4 years (IQR: 3.9-10.4). Twelve (13.7%) patients presented with shock. There was hospital admission in 89.7% of these cases, with 29.9% of the patients with MIS-C being admitted to the PICU.Conclusion: Most SARS-CoV-2 PCR-positive patients presented with a mild clinical course. Although rare, MIS-C emerges as a serious consequence with frequent PICU admission. Further understanding of the characteristics of COVID-19 disease could provide insights and guide the development of therapeutic strategies for target groups.(c) 2022 Elsevier Inc. All rights reserved

Structure and properties of polydiacetylene-containing peptide amphiphile fibres

Contains fulltext : 83167.pdf (publisher's version ) (Open Access)Radboud Universiteit Nijmegen, 10 februari 2011Promotor : Hest, J.C.M. van Co-promotor : Lowik, D.W.P.M.184 p