15 research outputs found
ジャイロトニックメソードにおける三次元的解析の事例研究
This research is the one that Juliu Horvath invented and developed in 1982. The purpose is rehabilitation and performance improvement for the dancers. We wanted to learn this method and whether it was effective. Therefore, we did some experiments in 1997-1998. The result, Weight, Fat(%), Fat(kg), Form and body composition have decreased. Moreover, the leg is raised and the ability, which is kept and done, has improved with forward and side. Ability on a joint movable region and the leg have also improved. At this time, we did the operation analysis of three dimensions of this method. The subject is a female as a sample. Result: 1. ARCH/CURL and TWIST & PULL exercise of the upper half of the body could be executed operated the one\u27s dominant arm large and smoothly. However, the operation of the student\u27s non-dominant arm had blurring compared with the student\u27s dominant arm. 2. ABDOMINAL exercise also had a right and left difference of the door pull and the student\u27s non-dominant arm had blurring compared with the student\u27s dominant arm. 3. As for SCISSOR and FULLCIRCLE exercise of lower limbs, the expansion degree of movement became a peak at about 50% of the maximum load muscular power. And, it is thought that the maintenance of the operation that aims of the load of 80% or more is difficult concerning these exercises
Analysis of the mechanism of radiation-induced upregulation of mitochondrial abundance in mouse fibroblasts.
Mitochondria strongly contribute to the maintenance of cellular integrity through various mechanisms, including oxidative adenosine triphosphate production and calcium homeostasis regulation. Therefore, proper regulation of the abundance, distribution and activity of mitochondria is crucial for the maintenance of cellular homeostasis. Previous studies have shown that ionizing radiation (IR) alters mitochondrial functions, suggesting that mitochondria are likely to be an important target of IR. Though IR reportedly influences cellular mitochondrial abundance, the mechanism remains largely unknown. In this study, we examined how IR influences mitochondrial abundance in mouse fibroblasts. When mouse NIH/3T3 cells were exposed to X-rays, a time-dependent increase was observed in mitochondrial DNA (mtDNA) and mitochondrial mass, indicating radiation-induced upregulation of mitochondrial abundance. Meanwhile, not only did we not observe a significant change in autophagic activity after irradiation, but in addition, IR hardly influenced the expression of two mitochondrial proteins, cytochrome c oxidase subunit IV and cytochrome c, or the mRNA expression of Polg, a component of DNA polymerase γ. We also observed that the expression of transcription factors involved in mitochondrial biogenesis was only marginally affected by IR. These data imply that radiation-induced upregulation of mitochondrial abundance is an event independent of macroautophagy and mitochondrial biogenesis. Furthermore, we found evidence that IR induced long-term cell cycle arrest and cellular senescence, indicating that these events are involved in regulating mitochondrial abundance. Considering the growing significance of mitochondria in cellular radioresponses, we believe the present study provides novel insights into understanding the effects of IR on mitochondria
